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Temporal arteritis

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https://www.readbyqxmd.com/read/28810043/amalric-triangular-syndrome-associated-with-outer-nuclear-layer-infarction
#1
Sean T Garrity, Eric J Holz, David Sarraf
An 85-year-old man presented with temporal headache and bilateral paracentral scotomas. Clinical examination, laboratory testing, and temporal artery biopsy confirmed the diagnosis of giant cell arteritis. Fluorescein angiography illustrated Amalric triangular choroidal infarction of the left eye. Spectral-domain optical coherence tomography of the left eye demonstrated outer nuclear layer abnormalities adjacent to the choroidal infarct. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:668-670.].
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28799318/giant-cell-arteritis-presenting-as-puo
#2
Sham Santhanam, Sampath Kumar Mani
Giant cell arteritis(GCA) is a primary granulomatous vasculitis affecting the large and medium sized arteries. We present here a case of GCA with pyrexia of unknown origin (PUO) as the presenting manifestation in the absence of other typical features. On evaluation, the patient had raised inflammatory markers with features of large vessel vasculitis on whole body PET-CT scan. The colour doppler ultrasonography(CDUS) of the temporal arteries showed bilateral halo sign. Since bilateral 'halo sign' is more specific for the diagnosis of GCA, temporal artery biopsy is not mandatory...
August 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28783392/occult-giant-cell-arteritis-with-an-abnormal-temporal-artery-finding-and-normal-blood-markers
#3
Simon Madge, Emma Samia-Aly
No abstract text is available yet for this article.
August 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28758156/varicella-zoster-virus-and-large-vessel-vasculitis-the-absence-of-an-association
#4
Gary W Procop, Charis Eng, Alison Clifford, Alexandra Villa-Forte, Leonard H Calabrese, Eric Roselli, Lars Svensson, Douglas Johnston, Gosta Pettersson, Edward Soltesz, Lisa Lystad, Julian D Perry, Alexander Blandford, Deborah A Wilson, Gary S Hoffman
OBJECTIVE: It is controversial whether microorganisms play a role in the pathogenesis of large and medium vessel vasculitides (eg, giant cell arteritis [GCA], Takayasu arteritis [TAK] and focal idiopathic aortitis [FIA]). Recent studies have reported the presence of Varicella Zoster Virus (VZV) within formalin-fixed, paraffin-embedded temporal arteries and aortas of about three-quarters or more of patients with these conditions, and in a minority of controls. In a prospective study, we sought to confirm these findings using DNA extracted from vessels that were harvested under surgically aseptic conditions and snap frozen...
2017: Pathogens & Immunity
https://www.readbyqxmd.com/read/28747747/involvement-of-monocyte-subsets-in-the-immunopathology-of-giant-cell-arteritis
#5
Yannick van Sleen, Qi Wang, Kornelis S M van der Geest, Johanna Westra, Wayel H Abdulahad, Peter Heeringa, Annemieke M H Boots, Elisabeth Brouwer
Monocytes/macrophages are critical in systemic and local inflammation in giant cell arteritis (GCA) and possibly in clinically overlapping polymyalgia rheumatica (PMR). Therefore, we aimed to understand the contribution of monocyte subsets and the CX3CR1-CX3CL1 and CCR2-CCL2 migratory pathways, to the pathology of GCA. Peripheral blood monocytes were enumerated in samples from newly-diagnosed, untreated GCA and PMR patients and after prednisone-induced remission. The distribution of classical (CD14(bright)CD16(neg)) and the more pro-inflammatory, intermediate (CD14(bright)CD16+) and non-classical (CD14(dim)CD16+) monocyte subsets was analysed by flow cytometry...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28688260/soil-aggregate-stability-and-size-selective-sediment-transport-with-surface-runoff-as-affected-by-organic-residue-amendment
#6
Pu Shi, Christian Arter, Xingyu Liu, Martin Keller, Rainer Schulin
Aggregate breakdown influences the availability of soil particles for size-selective sediment transport with surface runoff during erosive rainfall events. Organic matter management is known to affect aggregate stability against breakdown, but little is known about how this translates into rainfall-induced aggregate fragmentation and sediment transport under field conditions. In this study, we performed field experiments in which artificial rainfall was applied after pre-wetting on three pairs of arable soil plots (1...
July 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28680624/giant-cell-arteritis-with-polymyalgia-rheumatica-on-fdg-pet-ct
#7
Akira Baba, Kimiichi Uno, Yumi Okuyama, Yohei Munetomo, Shintaro Nakajima, Kennosuke Mizushina, Hideto Kameda
If there is no pain in the temporal artery, the diagnosis of giant cell arteritis (GCA) may be delayed and blindness may occur. Therefore, FDG-PET/CT is important as a modality for diagnosis of GCA. When GCA is suspected and F-18 FDG-PET/CT is performed, it is worthwhile to pay attention to shoulder and hip joints as polymyalgia rheumatica commonly presents with GCA.
July 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28675180/temporal-artery-biopsies-in-south-east-scotland-a-five-year-review
#8
S Gajree, S Borooah, N Dhillon, C Goudie, C Smith, P Aspinall, B Dhillon
Temporal artery biopsy is the gold standard investigation for the diagnosis of giant cell arteritis. The aim of this retrospective study was to investigate the use of temporal artery biopsy in diagnosing giant cell arteritis in south-east Scotland over a five-year period. We aimed to quantify success rates, and predictive factors for a positive biopsy, as well as compare the different specialities performing the biopsies. The data should enable the development of better criteria for referral for investigation of giant cell arteritis...
June 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/28663795/temporal-artery-biopsy-in-the-diagnosis-of-giant-cell-arteritis-does-the-end-justify-the-means
#9
K Bowling, J Rait, J Atkinson, G Srinivas
BACKGROUND: Early temporal artery biopsy is recommended in all patients with suspected cranial GCA (Giant Cell Arteritis) by the BSR (British Society of Rheumatology) and BHPR (British Health Professionals in Rheumatology) guidelines. This should be performed within one week ideally. AIM: To assess ACR (American College of Rheumatology) score at presentation and whether temporal artery biopsy result affects clinical management of the clinically suspected GCA patient...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28658131/polymyalgia-rheumatica-and-giant-cell-arteritis-three-challenges-consequences-of-the-vasculitis-process-osteoporosis-and-malignancy-a-prospective-cohort-study-protocol
#10
Amir Emamifar, Søren Hess, Oke Gerke, Anne Pernille Hermann, Helle Laustrup, Per Syrak Hansen, Peter Thye-Rønn, Niels Marcussen, Frank Svendstrup, Rannveig Gildberg-Mortensen, Jacob Christian Bang, Ziba Ahangarani Farahani, Stavros Chrysidis, Pia Toftegaard, Rikke Asmussen Andreasen, Sebastian le Greves, Hanne Randi Andersen, Rudolf Nezlo Olsen, Inger Marie Jensen Hansen
INTRODUCTION: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are common inflammatory conditions. The diagnosis of PMR/GCA poses many challenges since there are no specific diagnostic tests. Recent literature emphasizes the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to assess global disease activity in inflammatory diseases. 18F-FDG PET/CT may lead to the diagnosis at an earlier stage than conventional imaging and may also assess response to therapy...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28652258/response-to-artery-tertiary-lymphoid-organs-in-giant-cell-arteritis-are-not-exclusively-located-in-the-media-of-temporal-arteries-by-graver-et-al
#11
Francesco Ciccia, Aroldo Rizzo, Carlo Salvarani, Giovanni Triolo
No abstract text is available yet for this article.
June 26, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28638968/-large-vessel-vasculitis-giant-cell-arteritis-and-takayasu-arteritis
#12
P M Villiger
According to the Chapel Hill Classification, large vessel vasculitides encompass giant cell arteritis (GCA) and the histologically related Takakaysu arteritis (TAK). The two diseases lack autoantibodies and present with a systemic inflammatory response. GCA typically shows a sudden onset with profound sickness, loss of appetite and of body weight, and temporal headache. Due to the substantial risk of sudden blindness, diagnostic work-up has to be performed immediately and treatment started without delay. A close association between polymyalgia rheumatica (PMR) and GCA is well established...
June 21, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28638694/giant-cell-arteritis-polymyalgia-rheumatica-and-late-onset-rheumatoid-arthritis-can-they-be-components-of-a-single-disease-process-in-elderly-patients
#13
REVIEW
Cengiz Korkmaz, Pınar Yıldız
OBJECTIVE: To report two patients with giant cell arteritis (GCA) who developed rheumatoid arthritis (RA) and to review the literature in terms of coexistence of RA, GCA, and polymyalgia rheumatica (PMR). METHODS: We conducted a comprehensive review of the English literature from 1980 to 2015 to analyze data on the coexistence of GCA and RA. The PubMed, Web of Science, Proquest, and Ovid databases were searched for articles using the term RA combined with temporal arteritis, GCA, and PMR...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28608042/-granulomatous-reaction-pattern-of-the-skin-interstitial-granulomatous-dermatitis-lymphoma-vasculitis
#14
REVIEW
C Rose, K Holl-Ulrich
A particular diagnostic situation in the classification of a granulomatous dermatitis results when no circumscribed granulomas but instead a diffuse interstitial histiocytic inflammatory infiltrate, a granulomatous vasculitis or a neoplastic lymphocytic infiltrate is found. Interstitial granulomatous dermatitis was originally described in patients with arthritis. Later, it was recognized that there are also associations with other usually immunological diseases. Differentiating between interstitial granulomatous dermatitis and the interstitial form of granuloma annulare, early morphea and variants of borreliosis or scleromyxedema as well as interstitial granulomatous drug reaction can be very difficult...
June 12, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28606962/endothelin-1-promotes-vascular-smooth-muscle-cell-migration-across-the-artery-wall-a-mechanism-contributing-to-vascular-remodelling-and-intimal-hyperplasia-in-giant-cell-arteritis
#15
Ester Planas-Rigol, Nekane Terrades-Garcia, Marc Corbera-Bellalta, Ester Lozano, Marco A Alba, Marta Segarra, Georgina Espígol-Frigolé, Sergio Prieto-González, José Hernández-Rodríguez, Sara Preciado, Rodolfo Lavilla, Maria C Cid
BACKGROUND: Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced vascular remodelling leads to vaso-occlusive events. Circulating endothelin-1 (ET-1) is increased in patients with GCA with ischaemic complications suggesting a role for ET-1 in vascular occlusion beyond its vasoactive function. OBJECTIVE: To investigate whether ET-1 induces a migratory myofibroblastic phenotype in human TA-derived vascular smooth muscle cells (VSMC) leading to intimal hyperplasia and vascular occlusion in GCA...
June 12, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28588807/eosinophilic-angiitis-presenting-with-a-true-fusiform-temporal-artery-aneurysm
#16
Megan MacDiarmid, Dmitri Nepogodiev, Alok Tiwari, Martin Duddy, Martyn Carey, Paresh Jobanputra
Temporal artery aneurysm is a rare cause of temporal artery swelling in the absence of preceding trauma. Vasculitis other than giant cell arteritis, such as eosinophilic granulomatosis with polyangiitis, should be considered in such cases and a careful assessment of other medium-sized arteries undertaken.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28571674/gillies-temporal-incision-an-alternate-approach-to-superficial-temporal-artery-biopsy
#17
G Markose, R M Graham
The main complications of a biopsy of the superficial temporal artery using a standard preauricular approach include scars on the face, weakness of the temporal branch of the facial nerve, and the possible harvest of a disease-free segment of artery. We describe a modification of the Gillies temporal approach, which when placed at the junction of the frontal and parietal branch can be easily modified to harvest either branch. It avoids scarring to the face as it is hidden within the hairline. The incision placed with specific measurements and palpation is easily reproducible...
May 29, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28559710/cutaneous-nocardiosis-manifesting-as-a-frontal-mass-in-a-patient-with-giant-cell-arteritis
#18
Violeta Tincuta Briciu, Mirela Flonta, Mihaela Lupse, Laura Damian
We report the case of a subcutaneous abscess due to Nocardia spp. mimicking a spontaneous hematoma or an aneurysm of the temporal artery branch, in a giant cell arteritis patient treated with methylprednisolone and azathioprine. Ultrasonography, incision and drainage with cultures helped in the diagnosis. This case highlights the importance of considering rare pathogens in immunosuppressed patients, besides the more frequent disease complications.
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28523333/giant-cell-arteritis-with-arteritic-anterior-ischemic-optic-neuropathy
#19
Horia Tudor Stanca, Elena Suvac, Mihnea Munteanu, Dragoş Cătălin Jianu, Andrei Gheorghe Marius Motoc, Gavril Cosmin Roşca, Ovidiu Boruga
Giant cell arteritis (GCA) is an inflammatory vasculitis of unknown etiology that mainly involves large and medium arteries, particularly the cranial branches of the aorta. GCA with consecutive arteritic-anterior ischemic optic neuropathy (A-AION) has rarely been diagnosed in Romania. Recently, we encountered an 83-year-old patient who presented with left eye visual impairment and corresponding optic disc diffusely swollen and pale. He also had typical manifestations of GCA, such as malaise, and temporal headache, and a highly elevated erythrocyte sedimentation rate and C-reactive protein level...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28503707/the-value-of-ultrasound-in-diagnosing-extracranial-large-vessel-vasculitis-compared-to-fdg-pet-ct-a-retrospective-study
#20
Christian Löffler, Johannes Hoffend, Urs Benck, Bernhard K Krämer, Raoul Bergner
Large-vessel vasculitis (LVV) is a group of diseases mainly comprised of giant-cell arteritis (GCA), Takayasu arteritis, and a series of rare diseases like Behçet's disease, IgG4-related disease, infectious aortitis, and other unfrequent entities. Besides clinical and laboratory features, Doppler sonography (DS) can assist in establishing the diagnosis. Its diagnostic sensitivity has been evaluated in various studies, most of them, however, in temporal arteritis (TA) respectively in LVV with involvement of the temporal artery...
May 15, 2017: Clinical Rheumatology
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