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https://www.readbyqxmd.com/read/27867809/fixation-of-split-thickness-skin-graft-using-fast-clotting-fibrin-glue-containing-undiluted-high-concentration-thrombin-or-sutures-a-comparison-study
#1
Hyun Ho Han, Daiwon Jun, Suk-Ho Moon, In Sook Kang, Min Cheol Kim
OBJECTIVE: For skin defects caused by full-thickness burns, trauma, or tumor tissue excision, skin grafting is one of the most convenient and useful treatment methods. In this situation, graft fixation is important in skin grafting. This study was performed to compare the effectiveness of skin graft fixation between high-concentration fibrin sealant and sutures. There have been numerous studies using fibrin sealant for graft fixation, but they utilized slow-clotting fibrin sealant containing less than 10 IU/mL thrombin...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27779376/bio-inspired-single-walled-carbon-nanotubes-as-a-spider-silk-structure-for-ultra-high-mechanical-property
#2
Chengzhi Luo, Fangying Li, Delong Li, Qiang Fu, Chun-Xu Pan
Due to its unique hierarchical structure, natural spider silk features exceptional mechanical properties such as high tensile strength and great extensibility, making it one of the toughest materials. Herein, we design a bio-inspired spider silk single-walled carbon nanotubes (BISS-SWCNTs) that combine the hierarchical structure of spider silk and the high strength and conductivity of SWCNTs. To imitate the hierarchical structure, Fe nanoparticles are embedded on the surface of directly synthesized SWCNTs skeleton, and then followed by coating an amorphous carbon layer...
October 25, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27752035/application-of-compont-medical-adhesive-glue-for-tension-reduced-duraplasty-in-decompressive-craniotomy
#3
Yujia Zhou, Gesheng Wang, Jialin Liu, Yong Du, Lei Wang, Xiaoyong Wang
BACKGROUND The aim of this study was to evaluate the application of medical adhesive glue for tension-reduced duraplasty in decompressive craniotomy. MATERIAL AND METHODS A total of 56 cases were enrolled for this study from Jan 2013 to May 2015. All patients underwent decompressive craniotomy and the dura was repaired in all of them with tension-reduced duraplasty using the COMPONT medical adhesive to glue artificial dura together. The postoperative complications and the healing of dura mater were observed and recorded...
October 14, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27690705/refinement-of-tissue-engineering-chamber-implantation-in-the-rat
#4
Fabian Medved, Robert Haas, Cedric Bösch, Roderick F Pronk, Till Fischborn, Hans-Eberhard Schaller, Laurenz Weitgasser
PURPOSE: Rodent in vivo models that successfully generate new adipose, muscle, or vascular tissue in a tissue-engineering chamber (TEC) has advanced in the last decade. In this article, technical refinements in these operative foreign body implantations have been described to improve the execution of animal models in a way so that they can reduce wastage of time and resources. MATERIALS & METHODS: Male Sprague-Dawley rats were studied and randomly divided into two equal sized groups...
October 3, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27624413/effect-of-skin-coverage-method-following-subcuticular-suturing-on-wound-infection-rates-at-cesarean-delivery
#5
Jill M Westcott, Libby Crockett, Fang Qiu, Teresa G Berg
OBJECTIVE: The objective of this study was to determine whether use of cyanoacrylate skin glue following subcuticular skin closure was associated with a decrease in wound outcomes in comparison with subcuticular closure plus Steri-strips at cesarean delivery. METHODS: This was a retrospective cohort study of patients undergoing cesarean delivery at a single center over a two year period. The primary outcome of wound infection and secondary outcomes of wound separation and composite wound complication rate were assessed throughout the six week postpartum period...
September 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27593503/cosmetic-components-causing-contact-urticaria-a-review-and-update
#6
REVIEW
Lien Verhulst, An Goossens
Immediate skin reactions are common in dermatological practice, but may often be overlooked. The main objective of this article is to provide an update of the literature concerning immediate-type reactions or contact urticaria/contact urticaria syndrome caused by cosmetic ingredients in terms of immediate clinical symptoms, positive reactions following open, scratch or, most often, prick testing, and sometimes the detection of specific IgE antibodies. To this end, a selective search in different medical literature databases was performed...
December 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27563560/circumcision-with-glubran-%C3%A2-2-in-children-experience-of-italian-center
#7
Rossella Angotti, Elisa Cerchia, Francesco Molinaro, Anna Lavinia Bulotta, Francesco Ferrara, Edoardo Bindi, Mario Messina
BACKGROUND: Circumcision is one of the most common surgical procedures in the world. Despite it is known its wide prevalence for religious and medical reasons in children, it remains a controversial practice in paediatric age. To date, there is no described the gold standard technique to circumcise paediatric patients. We started to use glue for circumcision about 2 years ago. We designed this prospective study with the aim to compare two surgical techniques, which were used in our hospital to perform circumcision in children...
August 2016: Gland Surgery
https://www.readbyqxmd.com/read/27384972/comparison-of-the-wound-healing-efficacy-of-polyglycolic-acid-sheets-with-fibrin-glue-and-gelatin-sponge-dressings-in-a-rat-cranial-periosteal-defect-model
#8
Shinya Koshinuma, Shoko Murakami, Masaharu Noi, Takuya Murakami, Ken-Ichi Mukaisho, Hiroyuki Sugihara, Gaku Yamamoto
Oral surgical procedures occasionally require removal of the periosteum due to lesions, and these raw bone surfaces are prone not only to infection but also to scar formation during secondary healing. The objective of this study was to identify successful methods for reconstruction using periosteal defect dressings. We created 1-cm(2) defects in the skin and cranial periosteum of 10-week-old male Wistar rats under isoflurane anesthesia. The animals were assigned to three defect treatment groups: (1) polyglycolic acid sheets with fibrin glue dressing (PGA-FG), (2) Spongel® gelatin sponge dressing (GS), and (3) open wound (control)...
November 1, 2016: Experimental Animals
https://www.readbyqxmd.com/read/27384096/novel-approach-of-treatment-of-pilonidal-sinus-disease-with-thrombin-gelatin-matrix-as-a-sealant
#9
Hosam G Elbanna, Sameh Hany Emile, Mohamed Youssef, Waleed Thabet, Tito M Abd El-Hamed, Wagih M Ghnnam
BACKGROUND: Sacrococcygeal pilonidal sinus disease is a condition caused by insertion of fallen hair shafts into the skin. Different types of operations have been described for the management of pilonidal sinus, yet none of them have proven to be superior to the others. Recently, sealants like fibrin glue have been successfully used. OBJECTIVE: This study aimed to assess the efficacy of thrombin gelatin matrix as a new sealant for pilonidal sinus treatment. DESIGN: This was a prospective study conducted from March 2013 to March 2015...
August 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27373491/early-experience-in-the-management-of-postoperative-lymphatic-leakage-using-lipiodol-lymphangiography-and-adjunctive-glue-embolization
#10
Saebeom Hur, Ji Hoon Shin, In Joon Lee, Seung-Kee Min, Sang-Il Min, Sanghyun Ahn, Jinoo Kim, Sang Youn Kim, Minuk Kim, Myungsu Lee, Hyo-Cheol Kim, Hwan Jun Jae, Jin Wook Chung, Hyun Beom Kim
PURPOSE: To evaluate the safety and efficacy of Lipiodol lymphangiography and 3 adjunctive N-butyl cyanoacrylate (NBCA) glue embolization techniques for the management of postoperative lymphatic leakage. MATERIALS AND METHODS: This retrospective study included 27 patients with postoperative lymphatic leakage (17 with ascites, 3 with chylothorax, 6 with lymphoceles, and 1 with a skin fistula) who underwent Lipiodol lymphangiography for diagnostic and therapeutic purposes in 3 tertiary referral centers between August 2010 and January 2016...
August 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27254241/breast-rash-after-breast-reduction-a-case-study
#11
Alison E Evans, Emily B Ridgway
Breast reduction surgery is one of the most common procedures done by plastic surgeons. Although not detrimental to the final outcome, allergic reaction can negatively impact the postoperative course. This case presentation paints the classic picture of allergic reaction after breast surgery, likely due to skin glue. The typical signs of intense pruritus and erythematous rash surrounding incisions bilaterally are present. The patient was treated with our institutional protocol with good results. Our protocol is presented and further questions posed...
April 2016: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/27197606/a-new-method-for-skin-grafting-in-murine-model
#12
Mohammadreza Pakyari, Ali Farokhi, Mohsen Khosravi-Maharlooei, Ruhangiz T Kilani, Aziz Ghahary, Erin Brown
Skin transplantation provides an excellent potential model to investigate the immunology of allograft rejection and tolerance induction. Despite the theoretical ease of performing skin transplantation, as well as the potential of directly observing the reaction to the transplanted tissue, the poor reliability of skin transplantation in the mouse has largely precluded the use of this model. Furthermore, there is controversy regarding the most appropriate skin graft donor site due to poor success of back skin transplantation, as compared with the thinner ear or tail skin...
July 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27025812/comparison-of-2-ethyl-cyanoacrylate-and-2-butyl-cyanoacrylate-for-use-on-the-calvaria-of-cd1-mice
#13
Joanne J Sohn, Theresa M Gruber, Joanne L Zahorsky-Reeves, Greg W Lawson
Short-chain cyanoacrylates (SCCA), such as ethyl-2-cyanoacrylate (KrazyGlue, Aron Alpha, Columbus, OH) are commonly used as commercial fast-acting glues. Although once used in clinical medicine as skin adhesives, these products caused tissue toxicity and thus their use in live tissue was discontinued. SCCA were replaced by longer-chain versions (LCCA), such as butyl-cyanoacrylate (Vetbond, 3M, St Paul, Minnesota), which were found to be less toxic than the short-chain formulations. Some researchers prefer to use SCCA due to the belief that they create a stronger bond than do the longer-chain counterparts...
March 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27021482/antibiotics-and-antiseptics-for-surgical-wounds-healing-by-secondary-intention
#14
REVIEW
Gill Norman, Jo C Dumville, Devi Prasad Mohapatra, Gemma L Owens, Emma J Crosbie
BACKGROUND: Following surgery, incisions are usually closed by fixing the edges together with sutures (stitches), staples, adhesives (glue) or clips. This process helps the cut edges heal together and is called 'healing by primary intention'. However, a minority of surgical wounds are not closed in this way. Where the risk of infection is high or there has been significant loss of tissue, wounds may be left open to heal by the growth of new tissue rather than by primary closure; this is known as 'healing by secondary intention'...
March 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26932970/effects-of-a-fibrin-sealant-on-skin-graft-tissue-adhesion-in-a-rodent-model
#15
Mark D Balceniuk, Nicholas A Wingate, Howard Krein, Joseph Curry, David Cognetti, Ryan Heffelfiner, Adam Luginbuhl
OBJECTIVE: To establish a rodent model for skin grafting with fibrin glue and examine the effects of fibrin glue on the adhesive strength of skin grafts without bolsters. STUDY DESIGN: Animal cohort. SETTING: Academic hospital laboratory. SUBJECTS AND METHODS: Three skin grafts were created using a pneumatic microtome on the dorsum of 12 rats. Rats were evenly divided into experimental (n = 6) and control (n = 6) groups...
July 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26903733/scleral-necrosis-in-congenital-erythropoietic-porphyria-a-case-report-and-review-of-the-literature
#16
Shweta Agarwal, Parthopratim Dutta Majumder, Bhaskar Srinivasan, Geetha Iyer
A 28-year-old presented with complaints of severe pain and redness in the left eye since 2 weeks. He had similar complaints in the right eye 2 years back for which he had undergone a scleral patch graft. Best corrected visual acuity was 20/20 in both eyes. The right had a well vascularized scleral graft and rest of the anterior segment was normal. The left eye had inferior conjunctival congestion with an area of the scleral melt with uveal show just temporal to the limbus in the interpalbebral area. The cornea was clear and anterior chamber was quiet in the left eye...
September 2015: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/26850148/a-mussel-inspired-double-crosslinked-tissue-adhesive-intended-for-internal-medical-use
#17
Changjiang Fan, Jiayin Fu, Wenzhen Zhu, Dong-An Wang
UNLABELLED: It has been a great challenge to develop aldehyde-free tissue adhesives that can function rapidly and controllably on wet internal tissues with fine adhesion strength, sound biocompatibility and degradability. To this end, we have devised a mussel-inspired easy-to-use double-crosslink tissue adhesive (DCTA) comprising a dopamine-conjugated gelatin macromer, a rapid crosslinker (namely, Fe(3+)), and a long-term acting crosslinker (namely, genipin). As a mussel-inspired gluing macromer, dopamine is grafted onto gelatin backbone via an one-step reaction, the catechol groups of which are capable of performing strong wet adhesion on tissue surfaces...
March 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/26804594/the-proposed-use-of-radiofrequency-ablation-for-the-treatment-of-fistula-in-ano
#18
Kenneth M Keogh, Neil J Smart
Fistula in ano is a very common presentation to colorectal clinic. Embarrassment due to the symptoms makes accurate estimations of incidence difficult. It is estimated that up to 40% of peri-anal abscess will be accompanied by or preceded by a fistula. Fistulae can be classified into simple fistulae that involve no or minimal sphincter muscle and complex, which involve significant amounts of the anal sphincter muscle, possibly with multiple tracts. For complex fistulae a seton suture is usually placed through the tract and out through the anus to form a loop allowing pockets of sepsis to drain internally and externally and a mature tract of fibrous tissue to develop...
January 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/26777605/full-thickness-burns-caused-by-cyanoacrylate-nail-glue-a-case-series
#19
Noemi Kelemen, Eleni Karagergou, Sarah L Jones, Andrew N Morritt
Artificial (acrylic) nails are popular cosmetic enhancements that provide the user with the appearance of manicured nails, do not chip or crack, and are generally considered very safe to apply. We report three cases where full thickness thermal burns were sustained from nail glue adhesive (cyanoacrylate) during the application of artificial nails. All three cases underwent surgical debridement and split skin graft reconstruction. We carried out an experiment to characterize the exothermic reaction between nail glue and cotton leggings...
June 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/26747220/skin-glue-reduces-the-failure-rate-of-emergency-department-inserted-peripheral-intravenous-catheters-a-randomized-controlled-trial
#20
Simon Bugden, Karla Shean, Mark Scott, Gabor Mihala, Sean Clark, Christopher Johnstone, John F Fraser, Claire M Rickard
STUDY OBJECTIVE: Peripheral intravenous catheters are the most common invasive device in health care yet have very high failure rates. We investigate whether the failure rate could be reduced by the addition of skin glue to standard peripheral intravenous catheter care. METHODS: We conducted a single-site, 2-arm, nonblinded, randomized, controlled trial of 380 peripheral intravenous catheters inserted into 360 adult patients. The standard care group received standard securement...
August 2016: Annals of Emergency Medicine
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