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Quadriceps inhibition

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https://www.readbyqxmd.com/read/28533620/benefits-of-using-transcranial-magnetic-stimulation-as-a-tool-to-facilitate-the-chronic-knee-injury-rehabilitation
#1
Jae-Moo Lee, Ji-Hang Lee
[Purpose] While primary motor cortex activation has been implicated as a key factor in the arthrogenic muscle inhibition after knee joint injury, no viable rehabilitation protocol has been developed to accommodate this factor. In this study, transcranial magnetic stimulation was applied as a means of dissipating arthrogenic muscle inhibition by introducing temporary motor cortex excitation prior to the rehabilitation. [Subjects and Methods] Twenty-four subjects who have underwent the surgery due to knee injury were recruited, and randomly assigned to the control or the simulation groups...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533420/igf1-stimulates-greater-muscle-hypertrophy-in-the-absence-of-myostatin-in-male-mice
#2
Alexander Hennebry, Jenny M Oldham, Tea Shavlakadze, Miranda Grounds, Philip Sheard, Marta Fiorotto, Shelley J Falconer, Heather K Smith, Carole Berry, Ferenc Jeanplong, Jeremy Bracegirdle, Kenneth G Matthews, Gina Nicholas, Monica Senna-Salerno, Trevor Watson, Christopher D McMahon
Insulin-like growth factors (IGFs) and myostatin have opposing roles in regulating the growth and size of skeletal muscle, with IGF1 stimulating, and myostatin inhibiting, growth. However, it remains unclear whether these proteins have mutually dependent, or independent, roles. To clarify this issue, we crossed myostatin null (Mstn-/-) mice with mice over-expressing Igf1 in skeletal muscle (Igf1+) to generate six genotypes of male mice; wild-type (Mstn+/+), Mstn+/-, Mstn-/-, Mstn+/+:Igf1+, Mstn+/-:Igf1+ and Mstn-/-:Igf1+...
May 22, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28528818/patellar-tendon-vibration-reduces-the-increased-facilitation-from-quadriceps-to-soleus-in-post-stroke-hemiparetic-individuals
#3
Eric Maupas, Joseph-Omer Dyer, Sibele de Andrade Melo, Robert Forget
BACKGROUND: Stimulation of the femoral nerve in healthy people can facilitate soleus H-reflex and electromyography (EMG) activity. In stroke patients, such facilitation of transmission in spinal pathways linking the quadriceps and soleus muscles is enhanced and related to co-activation of knee and ankle extensors while sitting and walking. Soleus H-reflex facilitation can be depressed by vibration of the quadriceps in healthy people, but the effects of such vibration have never been studied on the abnormal soleus facilitation observed in people after stroke...
May 18, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28432421/the-effect-of-nitric-oxide-synthase-inhibition-with-and-without-inhibition-of-prostaglandins-on-blood-flow-in-different-human-skeletal-muscles
#4
Ilkka Heinonen, Bengt Saltin, Ylva Hellsten, Kari K Kalliokoski
PURPOSE: Animal studies suggest that the inhibition of nitric oxide synthase (NOS) affects blood flow differently in different skeletal muscles according to their muscle fibre type composition (oxidative vs glycolytic). Quadriceps femoris (QF) muscle consists of four different muscle parts: vastus intermedius (VI), rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) of which VI is located deep within the muscle group and is generally regarded to consist mostly of oxidative muscle fibres...
April 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28223939/no-influence-of-transcutaneous-electrical-nerve-stimulation-on-exercise-induced-pain-and-5-km-cycling-time-trial-performance
#5
Andrew W Hibbert, François Billaut, Matthew C Varley, Remco C J Polman
Introduction: Afferent information from exercising muscle contributes to the sensation of exercise-induced muscle pain. Transcutaneous electrical nerve stimulation (TENS) delivers low-voltage electrical currents to the skin, inhibiting nociceptive afferent information. The use of TENS in reducing perceptions of exercise-induced pain has not yet been fully explored. This study aimed to investigate the effect of TENS on exercise-induced muscle pain, pacing strategy, and performance during a 5-km cycling time trial (TT)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28217421/rapid-knee-extensions-to-increase-quadriceps-muscle-activity-in-patients-with-total-knee-arthroplasty-a-randomized-cross-over-study
#6
Rasmus Skov Husted, Lousia Wilquin, Thomas Linding Jakobsen, Anders Holsgaard-Larsen, Thomas Bandholm
BACKGROUND: Inhibition of the quadriceps muscle and reduced knee-extension strength is common shortly following total knee arthroplasty (weeks to months), due to reduced voluntary activation of the quadriceps muscle. In healthy subjects, strength training with heavy loads is known to increase agonist muscle activity, especially if the exercise is conducted using rapid muscle contractions. PURPOSE: The purpose of this study was to examine if patients with total knee arthroplasty could perform rapid knee-extensions using a 10 RM load four to eight weeks after surgery, and the degree to which rapid knee-extensions were associated with greater voluntary quadriceps muscle activity during an experimental strength training session, compared to that elicited using slow knee-extensions...
February 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28192829/tens-alleviates-muscle-weakness-attributable-to-attenuation-of-ia-afferents
#7
Y Konishi, P J McNair, D A Rice
Quadriceps weakness is a notable problem following knee damage. Research has shown effectiveness of TENS in improving Quadriceps weakness associated with arthrogenic muscle inhibition. However, these studies were not focused upon short term delivery of TENS, nor did they examine the potential mechanism(s). The present study examined the effect of 25-30 s of TENS upon weakness induced temporarily by a prolonged vibration. Subjects performed eccentric MVCs under 2 conditions (TENS and no-TENS). First, MVC was measured at baseline...
March 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28144695/greater-intracortical-inhibition-associates-with-lower-quadriceps-voluntary-activation-in-individuals-with-acl-reconstruction
#8
Brittney A Luc-Harkey, Matthew S Harkey, Derek N Pamukoff, Rebecca H Kim, Troy K Royal, J Troy Blackburn, Jeffery T Spang, Brian Pietrosimone
Decreased voluntary activation contributes to quadriceps weakness following anterior cruciate ligament reconstruction (ACLR). Alterations in neural excitability are likely responsible for reductions in quadriceps voluntary activation, and may be due to specific alterations in intracortical inhibition and facilitation. Therefore, we sought to determine if intracortical inhibition (SICI) and intracortical facilitation (ICF) associate with quadriceps voluntary activation in individuals with ACLR. Twenty-seven participants with a primary, unilateral ACLR were enrolled in this study...
April 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28142073/attentional-focusing-instructions-influence-quadriceps-activity-characteristics-but-not-force-production-during-isokinetic-knee-extensions
#9
David C Marchant, Matt Greig
The attentional focus emphasised in verbal instruction influences movement and muscle recruitment characteristics, with an external focus (onto movement effects) typically benefiting performance. However, contrasting findings suggest either a selective isolation or spreading activation effect on associated muscles as a result of internally focused instruction (movement characteristics). In the present experiment, participants completed maximal isokinetic concentric leg extension exercise using internally (muscle specific: vastus medialis oblique) or externally (outcome specific) focused instructions...
April 2017: Human Movement Science
https://www.readbyqxmd.com/read/28126423/effects-of-kinesio-taping-in-patients-with-quadriceps-inhibition-a-randomized-single-blinded-study
#10
RANDOMIZED CONTROLLED TRIAL
Kyung-Min Kim, Brandon Davis, Jay Hertel, Joseph Hart
OBJECTIVE: To determine effects of Kinesio taping (KT) on quadriceps activation and maximal voluntary isometric contraction (MVIC) in patients with quadriceps inhibition. DESIGN: Randomized, single-blinded. SETTING: Laboratory. PATIENTS: Sixteen participants (9 males, 7 females) with quadriceps inhibition, as determined by 90% or lower in central activation ratio (CAR), participated. MAIN OUTCOME MEASURES: Hoffmann reflex (H-reflex) of the vastus medialis and quadriceps CAR and MVIC were measured before taping, and participants were randomly allocated to either KT (KT application with tension) or sham (non-elastic tape application without tension) group...
March 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28060035/etiology-and-recovery-of-neuromuscular-fatigue-after-simulated-soccer-match-play
#11
Kevin Thomas, Jack Dent, Glyn Howatson, Stuart Goodall
PURPOSE: We profiled the etiology and recovery of neuromuscular fatigue after simulated soccer match play. METHODS: Fifteen semiprofessional players completed a 90-min simulated soccer match. Before, immediately after, and at 24, 48, and 72 h, participants completed a battery of neuromuscular, physical, and perceptual tests. Perceived fatigue and muscle soreness were assessed via visual analog scales. Maximum voluntary contraction (MVC) and twitch responses to electrical (femoral nerve) and magnetic (motor cortex) stimulation during isometric knee extensor contractions and at rest were measured to assess central (voluntary activation) and peripheral (quadriceps potentiated twitch force, Qtw,pot) fatigue, and responses to single and paired magnetic stimuli were assessed to quantify corticospinal excitability and short intracortical inhibition, respectively...
May 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27983542/pentoxifylline-attenuates-the-local-and%C3%A2-systemic-inflammatory-response-after%C3%A2-infrarenal-abdominal-aortic-ischemia-reperfusion
#12
Tibor Nagy, Péter Hardi, Ildikó Takács, Mónika Tóth, Laura Petrovics, Gábor Jancsó, László Sínay, Gábor Fazekas, Örs Pintér, Endre Arató
AIMS: We studied the new anti-inflammatory effects of non-specific phosphodiesterase (PDE) inhibitor pentoxifylline (PTX) on ischaemia-reperfusion injury and postconditioning of the lower extremities. We aimed to examine the oxidative stress parameters (OSP), the inflammatory response and the changes in structure of skeletal muscle after revascularization surgery. METHODS: 50 Wistar rats in five groups underwent a 60 min infrarenal aortic cross clamping. After the ischaemia in IR+PC group ischemic postconditioning was performed, intermittent 15 seconds reperfusion, 15 seconds ischaemic periods were applied four times...
2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27928123/consumption-of-japanese-yam-improves-lipid-metabolism-in-high-cholesterol-diet-fed-rats
#13
Yuri Kusano, Nobuko Tsujihara, Hironori Masui, Hana Kozai, Wakako Takeuchi
We investigated the effects of dietary Japanese yam (Dioscorea japonica Thunb.) on lipid metabolism. Male Wistar rats (6 wk old) were fed a high-cholesterol diet for 6 wk and then supplemented with 26% of Japanese yam or 0.5% of its constituent diosgenin for a further 4 wk of high-cholesterol feeding (C6-J4 and C6-D4 groups, respectively). In the C6-J4 group, body weight gains significantly decreased, but skeletal muscle fiber sizes in quadriceps significantly increased compared with the other groups. Furthermore, Japanese yam supplementation resulted in the reduction of triglyceride contents in their liver, quadriceps, and intra-abdominal visceral fat...
2016: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/27906065/dystrophin-deficient-dogs-with-reduced-myostatin-have-unequal-muscle-growth-and-greater-joint-contractures
#14
Joe N Kornegay, Daniel J Bogan, Janet R Bogan, Jennifer L Dow, Jiahui Wang, Zheng Fan, Naili Liu, Leigh C Warsing, Robert W Grange, Mihye Ahn, Cynthia J Balog-Alvarez, Steven W Cotten, Monte S Willis, Candice Brinkmeyer-Langford, Hongtu Zhu, Joe Palandra, Carl A Morris, Martin A Styner, Kathryn R Wagner
BACKGROUND: Myostatin (Mstn) is a negative regulator of muscle growth whose inhibition promotes muscle growth and regeneration. Dystrophin-deficient mdx mice in which myostatin is knocked out or inhibited postnatally have a less severe phenotype with greater total mass and strength and less fibrosis and fatty replacement of muscles than mdx mice with wild-type myostatin expression. Dogs with golden retriever muscular dystrophy (GRMD) have previously been noted to have increased muscle mass and reduced fibrosis after systemic postnatal myostatin inhibition...
April 4, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27865881/modulation-of-quadriceps-corticospinal-excitability-by-femoral-nerve-stimulation
#15
Dan Río-Rodríguez, Eliseo Iglesias-Soler, Miguel Fernandez-Del-Olmo
INTRODUCTION: We explored the conditioning effect of a percutaneous electrical pulse of the femoral nerve on cortical motor evoked responses in the rectus femoris muscle. METHODS: Corticospinal excitability of rectus femoris muscle was measured in sixteen healthy subjects, when a single transcranial magnetic pulse was preceded by an electrical femoral nerve stimulus, using twelve inter-stimulus intervals (from 10 to 275ms). We also evaluated the effects of the intensities of the transcranial magnetic and of the electrical pulses...
January 10, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/27834612/the-effectiveness-of-neuromuscular-electrical-stimulation-in-improving-voluntary-activation-of-the-quadriceps-a-critically-appraised-topic
#16
Cody B Bremner, William R Holcomb, Christopher D Brown, Melanie E Perreault
Clinical Scenario: Orthopedic knee conditions are regularly treated in sports medicine clinics. Rehabilitation protocols for these conditions are often designed to address the associated quadriceps strength deficits. Despite these efforts, patients with orthopedic knee conditions often fail to completely regain their quadriceps strength. Disinhibitory modalities have recently been suggested as a clinical tool that can be used to counteract the negative effects of arthrogenic muscle inhibition (AMI), which is believed to limit the effectiveness of therapeutic exercise...
November 11, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27813347/early-high-intensity-versus-low-intensity-rehabilitation-after-total-knee-arthroplasty-a-randomized-controlled-trial
#17
Michael Bade, Tamara Struessel, Michael Dayton, Jared Foran, Raymond Kim, Todd Miner, Pamela Wolfe, Wendy Kohrt, Douglas Dennis, Jennifer Stevens-Lapsley
OBJECTIVE: The purpose of this study was to examine the safety and efficacy of a high-intensity progressive rehabilitation protocol (HI) beginning 4 days after total knee arthroplasty (TKA) compared to a low-intensity (LI) rehabilitation protocol. METHODS: One hundred sixty-two participants (aged 63±7 years; 89 females) were randomized to either the HI group or LI group after TKA. Key components of the HI intervention were the utilization of progressive resistance exercises and a rapid progression to weight-bearing exercises and activities...
November 3, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27807421/cancer-and-chemotherapy-contribute-to-muscle-loss-by-activating-common-signaling-pathways
#18
Rafael Barreto, Giorgia Mandili, Frank A Witzmann, Francesco Novelli, Teresa A Zimmers, Andrea Bonetto
Cachexia represents one of the primary complications of colorectal cancer due to its effects on depletion of muscle and fat. Evidence suggests that chemotherapeutic regimens, such as Folfiri, contribute to cachexia-related symptoms. The purpose of the present study was to investigate the cachexia signature in different conditions associated with severe muscle wasting, namely Colon-26 (C26) and Folfiri-associated cachexia. Using a quantitative LC-MS/MS approach, we identified significant changes in 386 proteins in the quadriceps muscle of Folfiri-treated mice, and 269 proteins differentially expressed in the C26 hosts (p < 0...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27803618/effect-of-3-different-applications-of-kinesio-taping-denko%C3%A2-on-electromyographic-activity-inhibition-or-facilitation-of-the-quadriceps-of-males-during-squat-exercise
#19
Júlio C Serrão, Bruno Mezêncio, João G Claudino, Rafael Soncin, Pedro L Sampaio Miyashiro, Eric P Sousa, Eduardo Borges, Vinícius Zanetti, Igor Phillip, Luiz Mochizuki, Alberto C Amadio
Kinesio taping consists of a technique which uses the application of an elastic adhesive tape. It has become a widely used rehabilitation modality for the prevention and treatment of musculoskeletal disorders. The objective of this study was to verify the effect of the application of Kinesio Taping Denko(®) in three conditions (facilitation, inhibition, and placebo) on the electromyographic activity of the quadriceps and hamstrings muscles on facilitating or inhibiting the muscle function and on the perceived exertion during the barbell back squat exercise in healthy male subjects...
September 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/27753147/grape-pomace-improves-antioxidant-capacity-and-faecal-microflora-of-lambs
#20
I Kafantaris, B Kotsampasi, V Christodoulou, E Kokka, P Kouka, Z Terzopoulou, K Gerasopoulos, D Stagos, C Mitsagga, I Giavasis, S Makri, K Petrotos, D Kouretas
Grape pomace is a by-product of winemaking process and rich in bioactive compounds such as plant polyphenols having antioxidant and antimicrobial activities. As known, oxidative stress may cause a number of pathological conditions in farm animals and thus affecting animal welfare and production. Moreover, pathogenic bacteria affect animals' health status. Thus, the objective of this study was to investigate whether lambs' feed supplemented with grape pomace enhances the antioxidant mechanisms and reduces the growth of pathogenic bacteria...
October 18, 2016: Journal of Animal Physiology and Animal Nutrition
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