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Coarctation of aorta

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https://www.readbyqxmd.com/read/29777298/aortic-elasticity-deterioration-proves-intrinsic-abnormality-of-the-ascending-aorta-in-pediatric-turner-syndrome-unrelated-to-the-aortic-valve-morphology
#1
Christiane Pees, Julian A Heno, Gabriele Häusler, Diana-Alexandra Ertl, Talin Gulesserian, Ina Michel-Behnke
Turner syndrome (TS) is a common genetic disorder in females with high incidence of ascending aortic dilatation and even dissection occurring as early as in the second decade. Known risk factors (RF) are bicuspid aortic valves (BAV), coarctation of the aorta (CoA), and arterial hypertension. Since 10% of dissections occur in patients without RF, an intrinsic aortic wall abnormality has been postulated. This study aimed to investigate the elasticity of the ascending aorta as a surrogate marker of aortic wall texture...
May 18, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29772586/custom-made-stent-grafts-for-the-treatment-of-pseudoaneurysms-after-childhood-coarctation-surgery
#2
Mario Lescan, Andreas Hornung, Michael Hofbeck, Christian Schlensak
BACKGROUND:  Post-coarctation of the aorta (CoA) pseudoaneurysms is a complication of open repair. Thoracic endovascular repair (TEVAR) is feasible but complicated by proximity to the supra-aortic trunks and severe arch angulation. METHODS:  We describe three cases of post-CoA pseudoaneurysms treated with custom-made Relay stent grafts (Vascutek, Scotland). RESULTS:  Technical and clinical success was achieved in all three cases with no mortality, morbidity, endoleaks, or complications...
May 17, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29769512/turner-s-syndrome-with-severe-coarctation-of-the-aorta-a-case-report
#3
N Sheikh, J Arzu
Cardiovascular abnormalities are frequently encountered in patients with Turner's syndrome. A 12-year-old girl with Turner's syndrome (TS) was referred from the endocrinology department for management of hypertension. After Echocardiography and CT angiography, we confirmed that she had severe coarctation of the aorta, just distal to the left subclavian artery. Due to high-pressure gradient in the coarct segment, in presence of hypertension, we made the decision for percutaneous intervention of coarctation of aorta...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29754919/balloon-expandable-stents-for-recoarctation-of-the-aorta-in-small-children-two-centre-experience
#4
K Gendera, P Ewert, D Tanase, S Georgiev, T Genz, P Bambul Heck, T Moszura, I Malcic, J Cleuziou, A Eicken
BACKGROUND: In young patients with native aortic coarctation (CoA), the management of choice is surgery. However, in re-coarctation (re-CoA) surgery is associated with increased morbidity and even mortality. Some children with native CoA present relative contraindications for surgery. METHODS: From 2006 to 2017, thirty-four patients (male n = 20; 59%) from two centres with re-CoA (31) and native CoA (3) were managed by stent implantation with premounted balloon expandable stents...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29753817/arch-augmentation-via-median-sternotomy-for-coarctation-of-aorta-with-proximal-arch-hypoplasia
#5
W Hampton Gray, Winfield J Wells, Vaughn A Starnes, S Ram Kumar
BACKGROUND: Coarctation of the aorta can be associated with hypoplasia of the proximal transverse aortic arch. One approach to manage this condition is via left thoracotomy and extended end-to-end anastomosis with the expectation that the proximal arch will grow over time. Our preferred approach is to augment the aorta via midline sternotomy. We hypothesized that this approach is safe, durable and allows reliable growth of the aorta. METHODS: We identified the records of patients with biventricular anatomy who had coarctation of the aorta, hypoplasia of the proximal transverse arch, and no other cardiac lesion that would mandate cardiopulmonary bypass use and midline sternotomy...
May 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29752138/effect-of-stent-implantation-on-blood-pressure-control-in-adults-with-coarctation-of-the-aorta
#6
Jennifer J van der Burg, Evangeline G Warmerdam, Gregor J Krings, Folkert J Meijboom, Arie P van Dijk, M C Post, Gerrit Veen, Michiel Voskuil, Gertjan Tj Sieswerda
BACKGROUND: Stenting of coarctation of the aorta (CoA) generally results in good angiographic results and a decrease in transcoarctation pressure gradient. However, effect on blood pressure control is less clear. The goal of the current retrospective analysis was to investigate the effects of CoA stenting on blood pressure control. METHODS: A retrospective analysis was conducted in consecutive adult patients with a CoA who underwent a percutaneous intervention at one of the three participating hospitals...
April 10, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29739732/inherited-deletion-of-1q-hyperparathyroidism-and-signs-of-y-chromosomal-influence-in-a-patient-with-turner-syndrome
#7
Alejandro F Siller, Alex Shimony, Marwan Shinawi, Ina Amarillo, Louis P Dehner, Katherine Semenkovich, Ana María Arbeláez
We report a detailed phenotypic, cytogenetic, and molecular characterization of a patient diagnosed prenatally with Turner syndrome (TS). In addition to having typical TS clinical characteristics such as a webbed neck, high arched palate, and coarctation of the aorta, the patient had features less frequently seen in TS, including recurrent parathyroid adenomas, growth along the 75th-90th centiles on the TS height curve despite a minimal treatment with growth hormone, behavioral problems, and evidence of gonadal dysgenesis with testicular-like structures, such as seminiferous tubules lined by Sertoli cells and a contiguous nodule of Leydig cells...
May 9, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29733824/preoperative-aortic-arch-size-and-late-outcome-following-coarctation-repair-via-lateral-thoracotomy
#8
Preeti Ramachandran, Philip R Khoury, Robert H Beekman, Erik C Michelfelder, Peter B Manning, James S Tweddell, James F Cnota
BACKGROUND: The approach (lateral thoracotomy vs median sternotomy) to repair coarctation of aorta is frequently based on arch dimensions from the preoperative echocardiogram. Few studies have assessed the relationship between preoperative arch dimensions and late postoperative outcome. This study aims to define how preoperative arch dimensions relate to late outcomes and identify long term predictors of successful surgery. METHODS: We performed a retrospective review of 102 neonates and infants undergoing isolated coarctation repair via lateral thoracotomy between 2003-2012...
May 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29731787/mycotic-aneurysm-a-lesser-known-complication-of-coarctation-repair-in-a-child-managed-by-endovascular-aneurysm-repair
#9
M Tomar, R Parakh, A Bhan
We report a 12-year-old child diagnosed with mycotic aneurysm at the site of coarctation of aorta (CoA) repair. Surgical intervention, though very high risk, is the mainstay of management. In selected cases endovascular stenting is being reported in adults. Here we report the use of an endovascular stent in a child.
October 2017: Images in Paediatric Cardiology
https://www.readbyqxmd.com/read/29731785/aortic-coarctation-never-too-late-to-diagnose-never-too-late-to-treat
#10
L Conti, S Borg Savona, T Spiteri, J Degiovanni, A Borg, M Caruana
We present two cases of severe aortic coarctation detected in adulthood and who underwent successful relief by transcatheter stent deployment using a new covered stent, Optimus® stent (AndraTec GmbH Koblenz, Germany). One patient is a 46-year old female with resistant arterial hypertension, in whom coarctation was suspected on a follow-up transthoracic echocardiogram for bicuspid aortic valve disease and subsequently confirmed on magnetic resonance imaging. The second patient is a 68-year old male whose coarctation was diagnosed incidentally at coronary angiography being performed as part of the preoperative work-up for severe aortic stenosis...
July 2017: Images in Paediatric Cardiology
https://www.readbyqxmd.com/read/29731027/prognostic-role-of-hypertensive-response-to-exercise-in-patients-with-repaired-coarctation-of-aorta
#11
Vidhushei Yogeswaran, Heidi M Connolly, Mohamad Al-Otaibi, Naser M Ammash, Carole A Warnes, Sameh M Said, Alexander C Egbe
BACKGROUND: This study aimed to determine the prevalence of hypertensive response to exercise (HRE) and its association with cardiovascular adverse events (CAEs) in patients with repaired coarctation of aorta (rCOA). METHODS: We retrospectively reviewed records of adult patients with rCOA who had cardiopulmonary exercise tests (CPETs) and follow-up from 1994 to 2014 at Mayo Clinic. Patients with residual COA, defined as aortic isthmus peak velocity >2.5 m/s, were excluded...
May 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29730347/extra-anatomic-bypass-of-a-complex-adult-coarctation-how-i-do-it
#12
EDITORIAL
Eric N Feins, Arminder S Jassar, Luis F Tapias, Eric M Isselbacher, Thoralf M Sundt
Complex adult coarctations associated with arch hypoplasia and aneurysms require a range of surgical approaches depending upon anatomy. Extra-anatomic bypass is an important strategy that enables the surgeon to avoid the risks of extensive dissection/mobilization. Extra-anatomic bypass can be accomplished from the ascending to lower descending thoracic aorta via an intra-pericardial route lateral to the right atrium and posterior to the IVC; however, this approach incompletely addresses post-stenotic aneurysmal disease...
May 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29726634/successful-exclusion-of-an-aortic-aneurysm-with-a-novel-ptfe-tube-covered-cobalt-chromium-stent-in-a-pediatric-patient-with-native-coarctation-of-the-aorta
#13
Johannes Nordmeyer, Peter Kramer, Felix Berger, Stephan Schubert
Treatment of aneurysmal lesions in the context of coarctation of the aorta (CoA) is a challenging task and these lesions are rare in children. An 11-year-old boy was incidentally diagnosed with native CoA and concomitant complex aneurysmal lesions during medical check-up for arterial hypertension. Pre-catheterization imaging was performed with computed tomography (CT), which showed a mild CoA and two native aneurysms that were juxtaposed to the origin of the left subclavian artery. For planning and guidance of the catheter procedure, image fusion software was used with an overlay from pre-registered three-dimensional reconstruction images on live fluoroscopy...
May 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29720173/clinical-validation-and-assessment-of-aortic-hemodynamics-using-computational-fluid-dynamics-simulations-from-computed-tomography-angiography
#14
Yulei Zhu, Rui Chen, Yu-Hsiang Juan, He Li, Jingjing Wang, Zhuliang Yu, Hui Liu
BACKGROUND: Hemodynamic information including peak systolic pressure (PSP) and peak systolic velocity (PSV) carry an important role in evaluation and diagnosis of congenital heart disease (CHD). Since MDCTA cannot evaluate hemodynamic information directly, the aim of this study is to provide a noninvasive method based on a computational fluid dynamics (CFD) model, derived from multi-detector computed tomography angiography (MDCTA) raw data, to analyze the aortic hemodynamics in infants with CHD, and validate these results against echocardiography and cardiac catheter measurements...
May 2, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29719804/unilateral-pulmonary-artery-agenesis-an-unusual-cause-of-unilateral-ards
#15
Lakshmi Saladi, Swati Roy, Gilda Diaz-Fuentes
Unilateral pulmonary artery agenesis (UPAA) is a rare malformation that can present as an isolated anomaly or may be associated with certain congenital cardiac anomalies, such as tetralogy of Fallot, atrial septal defect, coarctation of aorta, right aortic arch, truncus arteriosus and pulmonary atresia. Clinical presentation is non-specific which makes the diagnosis elusive; chronic dyspnea, hemoptysis or recurrent infections are the most common manifestations. Patients may remain asymptomatic until adulthood...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29695645/non-invasive-measurement-of-cardiac-output-in-children-with-repaired-coarctation-of-the-aorta-using-electrical-cardiometry-compared-to-transthoracic-doppler-echocardiography
#16
Luis Altamirano-Diaz, Eva Welisch, Adam A Dempsey, Teresa Sohee Park, Michael Grattan, Kambiz Norozi
Objective
 To evaluate the equivalence of the ICON® electrical cardiometry (EC) haemodynamic monitor to measure cardiac output (CO) relative to transthoracic Doppler echocardiography (TTE) in paediatric patients with repaired coarctation of the aorta (CoA). 
 
 Approach
 A group of n=28 CoA patients and n=27 matched controls were enrolled. EC and TTE were performed synchronously on each participant and CO measurements compared using linear regression and Bland-Altman analysis...
April 26, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29691159/a-cross-sectional-study-of-the-prevalence-of-exercise-induced-hypertension-in-childhood-following-repair-of-coarctation-of-the-aorta
#17
Taryn L Luitingh, Melissa G Y Lee, Bryn Jones, Remi Kowalski, Sofia Weskamp Aguero, Jane Koleff, Diana Zannino, Michael M H Cheung, Yves d'Udekem
BACKGROUND: Exercise-testing may be a more tolerable method of detecting hypertension in children after coarctation repair compared to gold-standard 24-hour ambulatory blood pressure (BP) monitoring (ABPM). This study aims to determine the prevalence of exercise-induced hypertension and end-organ damage in children after coarctation repair, and the effectiveness of exercise-testing compared to 24-hour ABPM in this population. METHODS: Exercise-testing (Bruce protocol), transthoracic echocardiogram, 24-hour ABPM, and pulse wave velocity were performed in 41 patients aged 8 to 18 years with previous coarctation repair...
March 27, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29688517/complex-coarctation-of-the-aorta-requiring-a-third-redo-operation
#18
Damian Gimpel, David J McCormack, A El-Gamel
Coarctation of the aorta can require multiple redo surgeries. It is extremely pertinent to plan for this and ensure that each operation is performed with future repair in mind. We present a rare case and the subsequent management of competitive flow in coarctation of the aorta requiring a fourth operation for repair.
April 24, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29687876/the-intervention-of-enalapril-maleate-and-folic-acid-tablet-on-the-expressions-of-the-grp78-and-chop-and-vascular-remodeling-in-the-vascular-smooth-muscle-cells-of-h-hypertensive-rats-with-homocysteine
#19
F Lu, L-Y Zhao, Z-M Zhang, Q Zou, X-L Yu, C-Y Wei
OBJECTIVE: GRP78 and CHOP play essential roles in endoplasmic reticulum stress (ERS) of the vascular smooth muscle cells. We aim to investigate the effect of enalapril maleate and folic acid tablet on the expressions of GRP78 and CHOP and vascular remodeling in a homocysteine (HCY)-treated hypertensive rat model. MATERIALS AND METHODS: The hypertensive rat model was established with the technique of coarctation in the abdominal aorta, and the blood pressure of the rat was measured with the non-destructive tail-cuff method two weeks after operation...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29673637/arterial-switch-ventricular-septation-and-fontan-takedown-for-double-inlet-left-ventricle
#20
Shu-Chien Huang, Shyh-Jye Chen, Yi-Chia Wang, Chi-Hsiang Huang, Shuenn-Nan Chiu, Yih-Sharng Chen
A patient with double inlet left ventricle with transposition of great arteries, and severe coarctation of the aorta received aortoplasty and pulmonary artery banding, followed by bidirectional Glenn shunt and extracardiac total cavopulmonary connection(TCPC). Severe subaortic stenosis and increased atrio-ventricular valve regurgitation were noted 4 years after TCPC.
April 16, 2018: Annals of Thoracic Surgery
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