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Vesicoureteral reflux

İsa Yılmaz, Harun Peru, Fatma H Yılmaz, Tamer Sekmenli, İlhan Çiftçi, Fatih Kara
INTRODUCTION: The aim was to investigate the relationship between vesicoureteral reflux (VUR) and renal damage in non-febrile, febrile for the first time and recurrent urinary tract infection (UTI) patients. The secondary aim was to determine whether C-reactive protein (CRP) in febrile UTIs could be a predictor of renal scarring. POPULATION AND METHODS: This prospective study included non-febrile, febrile for the first time and recurrent pediatric UTI cases. The routine lab analyses comprised a complete blood count, urea, creatinine, fully automated urinalysis, urine culture and CRP analyses...
August 1, 2018: Archivos Argentinos de Pediatría
Maria Veronica Rodriguez, William R Boysen, Mohan S Gundeti
OBJECTIVE: To describe surgical tips for robot-assisted laparoscopic (RAL) common sheath ureteral reimplantation using the previously reported LUAA technique in patients with duplex renal collecting systems, and to assess the efficacy of this technique by reviewing operative outcomes in a single-institution case series. METHODS: We retrospectively reviewed a consecutive series of patients with duplicated collecting systems and vesicoureteral reflux (VUR) who underwent RAL extravesical common sheath ureteral reimplantation at a single medical center from 2010 to 2017...
July 2, 2018: Journal of Pediatric Urology
Susanna Negrisolo, Andrea Carraro, Giulia Fregonese, Elisa Benetti, Franz Schaefer, Marta Alberti, Salvatore Melchionda, Rita Fischetto, Mario Giordano, Luisa Murer
Nail Patella syndrome (NPS) is a rare autosomal dominant disease characterized by varying degrees of patella, nail, and elbows dysplasia and also ocular and renal congenital abnormalities. The renal involvement, ranging from hematuria and proteinuria to end-stage renal disease, is present in 22-60% of NPS cases. Heterozygous variants in LMX1B are known to be responsible of NPS and it has been hypothesized that the variable expressivity is due to the interaction of LMX1B with other developmental genes. We reported a case of co-presence of LMX1B and PAX2 variants in a child with extrarenal manifestation of NPS and end-stage renal disease but congenital bilateral renal hypodysplasia and vesicoureteral reflux...
July 4, 2018: European Journal of Human Genetics: EJHG
Matthew A Thimm, Daniel Rhee, Clifford M Takemoto, Wikrom Karnsakul, Carmen Cuffari, Anthony L Guerrerio, Alejandro Garcia, John Gearhart, Thierry A G M Huisman, Misun Hwang
Contrast-enhanced ultrasound (CEUS) is a versatile imaging modality that improves the diagnostic potential of conventional ultrasound. It allows for portable imaging at the bedside. In this paper, we illustrate how CEUS can be used in evaluating several focal lesions in the pediatric population, including liver hemangioma, telangiectasias, splenic hamartomas, and bladder lesions. We describe the ultrasound findings and contrast enhancement patterns associated with these lesions. Findings are correlated with MRI, CT, and/or pathology when available...
July 3, 2018: European Journal of Pediatrics
Rachel E Selekman, Daniel J Shapiro, John Boscardin, Gabrielle Williams, Jonathan C Craig, Per Brandström, Marco Pennesi, Gwenalle Roussey-Kesler, Pankaj Hari, Hillary L Copp
CONTEXT: Limited data exist regarding uropathogen resistance in randomized controlled trials of urinary tract infection (UTI) prevention and antibiotic prophylaxis. OBJECTIVE: To assess the effect of prophylaxis on developing a multidrug-resistant first recurrent UTI among children with vesicoureteral reflux. DATA SOURCES: Cochrane Kidney and Transplant Specialized Register through May 25, 2017. STUDY SELECTION: Randomized controlled trials of patients ≤18 years of age with a history of vesicoureteral reflux being treated with continuous antibiotic prophylaxis compared with no treatment or placebo with available antibiotic sensitivity profiles...
June 28, 2018: Pediatrics
T Kawal, A K Srinivasan, J Chang, C Long, D Chu, A R Shukla
OBJECTIVE: Urinary retention following robotic-assisted laparoscopic extravesical ureteral reimplantation (RALUR) is proposed to be due to traction or injury of the pelvic parasympathetic nerve plexus during distal ureteral dissection. Nerve-sparing techniques have been employed to avoid injury to the pelvic plexus, either directly or indirectly. This single-center study assessed postoperative urinary retention rates after extravesical RALUR and investigated whether demographic or operative factors could predict this occurrence...
June 7, 2018: Journal of Pediatric Urology
Veerbhadra Radhakrishna, Krishna Kumar Govindarajan, Kumaravel Sambandan, Bibekanand Jindal, BikashKumar Naredi
INTRODUCTION: Children with solitary functioning kidney (SFK) are prone to develop long term problems, which are not well represented in the literature. The extent to which the presence of associated congenital anomalies of kidney and urinary tract (CAKUT) further de-stabilize renal function is to be addressed. OBJECTIVE: This study was conducted to evaluate the etiology, presentation, presence of CAKUT, and renal damage in children with SFK. METHODS: All children with SFK who presented to the department of pediatric surgery from March 2014 to May 2016 were included in the study...
June 18, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
Gheorghe Adrian Bumbu, Mihail Claudius Berechet, Karim Nacer, Gheorghe Bumbu, Nina Ionovici, Bogdan Andrei Bumbu
Congenital hydronephrosis caused by ureteral anomalies, like ureteral duplicity, megaureter, ureteral ectopy and ureterocele, must be differentiated from ureteropelvic junction obstruction (UJO) hydronephrosis and from the hydronephrosis caused by vesicoureteral reflux. These represent a differentiated branch of congenital abnormalities in children even if not so common, but this fact should not be disconsidered. Over a five years period, from 111 operated children in our Clinic, we performed 13 interventions for congenital hydronephrosis, 11 (84...
2018: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
Luis A Guerra, Melise A Keays, M J Purser, S Y Wang, Michael P Leonard
INTRODUCTION: There are a small number of reports in the literature describing bladder rupture during cystograms in children. We hypothesized that children undergoing cystograms may have their bladder overfilled during the test. We aimed to evaluate the current practice when performing cystograms in our institution, contrasting actual volume used to fill the bladder to the age-adjusted bladder capacity. METHODS: We performed a retrospective review of all voiding cystourethrograms(VCUG) and radionuclide cystograms (RNC) performed at the Children's Hospital of Eastern Ontario from 2006-2013...
June 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Jonathan C Routh
No abstract text is available yet for this article.
June 20, 2018: Journal of Urology
Coral Hanevold, Susan Halbach, Jin Mou, Karyn Yonekawa
BACKGROUND: We have noted a large number of referrals for abnormal kidney imaging and laboratory tests and postulated that such referrals have increased significantly over time. Understanding changes in referral patterns is helpful in tailoring education and communication between specialists and primary providers. METHODS: We performed a retrospective chart review of new patient referrals to Mary Bridge Children's Nephrology clinic for early (2002 to 2004) and late (2011 to 2013) cohorts...
June 19, 2018: BMC Pediatrics
Emmanuel Ademola Anigilaje
BACKGROUND: Although urinary tract infection (UTI) resolves with prompt treatment in a majority of children, some children, especially those aged less than 5 years, also develop renal parenchymal scarring (RPS). RPS causes high blood pressure that may lead to severe chronic kidney disease and end-stage renal disease (ESRD). Although the risk of UTI is higher in white children than in black children, it is unknown whether RPS is more common in white children than in black children as data are scarce in this regard...
June 14, 2018: JMIR Research Protocols
Sara Fuentes, Andrés Gómez-Fraile, Isabel Carrillo-Arroyo, Daniel Cabezalí-Barbancho, Cristina Tordable-Ojeda
OBJECTIVES: In recent years, different studies have mentioned the recurrence of vesicoureteral reflux (VUR) endoscopically resolved, an exceptional event after open surgery. The aim of this study is to describe the evolution of the cases of recurrence identified in our center to assess the importance of this event. METHOD: We have identified the cases of VUR that recurred after successful endoscopic treatment in our anesdepartment. We have analyzed diagnostic tests, management and final outcome...
June 2018: Archivos Españoles de Urología
B Chertin, E Mele, S Kocherov, S Zilber, S Gerocarni Nappo, N Capozza
BACKGROUND: It is extremely important to not only address the short-term success following endoscopic correction of vesicoureteral reflux (VUR) but also the long-term efficacy and safety of the tissue augmenting substance utilized for endoscopic correction. OBJECTIVE: This study retrospectively evaluated all cases of ureterovesical junction (UVJ) obstruction following endoscopic treatment of VUR over the last 5 years utilizing two tissue augmenting substances, with special emphasis on the safety of Vantris® , and performed clinical and histological review of these patients...
May 25, 2018: Journal of Pediatric Urology
Jonathan S Ellison, Geolani W Dy, Benjamin C Fu, Sarah K Holt, John L Gore, Paul A Merguerian
BACKGROUND: Boys with urinary tract abnormalities may derive a greater benefit from newborn circumcision for prevention of urinary tract infection (UTI) than the general population. However, the effect of newborn circumcision on UTI is not well characterized across the etiological spectrum of hydronephrosis. We hypothesized that boys with an early diagnosis of hydronephrosis who undergo newborn circumcision will have reduced rates of UTI. METHODS: The MarketScan data set, an employer-based claims database, was used to identify boys with hydronephrosis or hydronephrosis-related diagnoses within the first 30 days of life...
July 2018: Pediatrics
Kazuya Matsumura, Kyoko Sugii, Midori Awazu
BACKGROUND/AIMS: Children with a solitary functioning kidney have a risk of renal injury caused by hyperfiltration. Timely intervention with renin-angiotensin inhibitors may be beneficial. We examined whether trajectory of estimated glomerular filtration rate (eGFR) would predict renal injury, defined as microalbuminuria/proteinuria, hypertension, and/or a decline in eGFR. METHODS: Seventeen patients (male 7, female 10) with multicystic dysplastic kidney (MCDK; median age 13 years, range 6-19 years) followed in our clinic were examined retrospectively...
June 7, 2018: Nephron
Çağla Serpil Doğan, Nevin Semerci Koyun, Gülşah Kaya Aksoy, Bülent Çekiç, Murat Savaş, Elif Çomak
OBJECTIVE: In this study, we aimed to assess renal outcomes of delayed diagnosis of dilating primary vesicoureteral reflux (VUR) following recurrent febrile urinary tract infections (fUTIs) and its diagnostic imaging procedures. MATERIAL AND METHODS: The medical records of patients who underwent ultrasonography (US), non- acute dimercaptosuccinic acid (Tc-99mDMSA) scintigraphy and voiding cystourethrography (VCUG), and who were older than 2 years at the time of VUR diagnosis were retrospectively reviewed...
May 31, 2018: Turkish Journal of Urology
Rabea A Gadelkareem, Ahmed A Shahat, Mohamed F Abdelhafez, Ahmed M Moeen, Abdelrady S Ibrahim, Ahmed S Safwat
OBJECTIVES: The study aimed to present our center's experience with long-standing urethral stones in male children with normal urethra. MATERIALS AND METHODS: Retrospective search of our center data was done for the cases of long-standing urethral stones with normal urethra in male children during the period July 2001 - June 2016. Demographic and clinical data were studied. RESULTS: Of more than 54,000 urolithiasis procedures, 17 male children (0...
June 6, 2018: Urologia Internationalis
Eda Tokat, Serhat Gurocak, Iyimser Ure, Cenk Acar, Zafer Sınık, Mustafa Ozgur Tan
BACKGROUND/PURPOSE: The "European Association of Urology (EAU) Guidelines on Vesicoureteral Reflux (VUR) in Children (September 2012)" established risk classification by analyzing and defining risk factors for each patient. In this study we aimed to investigate how our initial treatment procedures were affected by EAU/ESPU guideline vesicoureteral reflux risk grouping and to compare the early clinical results of treatments performed before and after the risk classification in our patients with VUR...
June 2, 2018: Journal of Pediatric Surgery
Aslihan Kara, Metin Kaya Gurgoze, Mustafa Aydin, Zehra Pinar Koc
BACKGROUND: To evaluate the clinical features of patients with multicystic dysplastic kidney (MCDK) and present our data on these children. METHODS: The medical files of children diagnosed with MCDK between January 2008 and November 2015 were retrospectively reviewed. Their demographic, clinical, laboratory and radiological data were evaluated. RESULTS: Of 128 children with MCDK enrolled into study, 82 (64.1%) were male, and 46 (35.9%) were female (p<0...
June 1, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
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