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https://www.readbyqxmd.com/read/29326848/the-knowledge-of-eye-physicians-on-local-anesthetic-toxicity-and-intravenous-lipid-treatment-questionnaire-study
#1
Aykut Urfalıoğlu, Selma Urfalıoğlu, Gözen Öksüz
Objectives: To evaluate the knowledge of ophthalmologists regarding local anesthesia toxicity syndrome (LATS) and intravenous lipid emulsion used in treatment, and to raise awareness of this issue. Materials and Methods: A questionnaire comprising 14 questions about demographics, local anesthesia (LA) use, toxicity, and treatment methods was administered to ophthalmologists at different hospitals. Results: The study included 104 ophthalmologists (25% residents, 67...
December 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29324426/a-sweet-solution-the-use-of-medical-grade-honey-on-oral-mucositis-in-the-pediatric-oncology-patient
#2
Ferne T Elsass
INTRODUCTION: Pediatric patients develop mucositis when receiving treatments such as chemotherapy and radiation; the most common and sensitive is oral mucositis. Mouth rinses containing antimicrobial, antihistamine, and analgesic medications are the mainstay for pediatric patients; however, patients often refuse these rinses due to the taste or texture. Also, patients under 1 year of age are unable to use these products. OBJECTIVE: Herein, the improvement of oral mucositis with standard oral care and additional use of active Leptospermum honey in pediatric oncology patients after chemotherapy is demonstrated...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29317281/an-assessment-of-the-use-of-antihistamines-in-the-management-of-atopic-dermatitis
#3
Alice He, Steven R Feldman, Alan B Fleischer
BACKGROUND: Antihistamines are often used to treat pruritus associated with atopic dermatitis (AD) despite lack of evidence for their efficacy. The American Academy of Dermatology does not recommend the general use of antihistamines in the management of AD, although the value of short-term sedating antihistamine use for insomnia secondary to itch is recognized. OBJECTIVE: To assess the use of sedating and non-sedating antihistamines for AD from 2003-2012. METHODS: The National Ambulatory Medical Care Survey (NAMCS) provided data on physician visits from 2003-2012...
January 6, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29314223/delayed-type-hypersensitivity-to-vaccine-aluminum-adjuvant-causing-subcutaneous-leg-mass-and-urticaria-in-a-child
#4
Samantha C Gordon, Diana W Bartenstein, Shahein H Tajmir, Johanna S Song, Elena B Hawryluk
A 3-year-old girl presented with a 7-month history of a waxing and waning left thigh mass associated with pruritus and erythema at the site of two previous DTaP-HepB-IPV vaccinations. Patch testing was positive to aluminum chloride, supporting a diagnosis of vaccine granuloma secondary to aluminum allergy; her symptoms had been well controlled with antihistamines and topical steroids. Injection site granulomas are a benign but potentially bothersome reaction to aluminum-containing immunizations that can be supportively managed, and we encourage strict adherence to the recommended vaccine schedule in this setting...
January 4, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29314003/atopic-allergic-conditions-and-pancreatic-cancer-risk-results-from-the-multiethnic-cohort-study
#5
Brian Z Huang, Loic Le Marchand, Christopher A Haiman, Kristine R Monroe, Lynne R Wilkens, Zuo-Feng Zhang, Veronica Wendy Setiawan
Previous case-control studies have suggested that atopic allergic conditions (AACs) are inversely associated with pancreatic cancer, but this relationship has not been supported in many prospective settings. In this study, we investigated the influence of AACs (asthma, hay fever, or allergy) and the treatment of these conditions on pancreatic cancer risk among participants of the Multiethnic Cohort Study (MEC). AACs and antihistamine use were assessed via a baseline questionnaire when participants joined the MEC in 1993-1996...
January 4, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29310760/the-paradox-of-antihistamine-hypersensitivity
#6
EDITORIAL
Krzysztof Rutkowski, Philip H Li, Annette Wagner
No abstract text is available yet for this article.
January 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29309271/current-epidemiology-and-management-of-radiocontrast-associated-acute-and-delayed-onset-hypersensitivity-a-review-of-the-literature
#7
Eric M Macy
Radiocontrast-associated acute-onset hypersensitivity reactions now occur less frequently than before 1990, when high-osmolar, ionic, radiocontrast agents were widely used. Premedication with corticosteroids and antihistamines does not reliably prevent recurrent low-osmolar radiocontrast-associated acute hypersensitivity reactions. Corticosteroid prophylaxis for acute hypersensitivity currently causes more morbidity than benefit. The specific radiocontrast agent that is associated with a patient's adverse reaction must be displayed in the drug intolerance or drug "allergy" field of their electronic health record to enable effective management and prevention of future reactions...
2018: Permanente Journal
https://www.readbyqxmd.com/read/29308115/etiology-of-chronic-urticaria-the-ecuadorian-experience
#8
I Cherrez Ojeda, E Vanegas, M Felix, V Mata, S Cherrez, D Simancas-Racines, L Greiding, J Cano, A Cherrez, Juan Carlos Calderon
Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its treatment. Methods: We performed a retrospective study involving 112 patients diagnosed with CU using a Checklist for a complete chronic urticaria medical history. Demographic and clinical variables were collected. The etiology of CU was classified using the EAACI/GA2LEN/EDF/WAO guideline...
2018: World Allergy Organization Journal
https://www.readbyqxmd.com/read/29301162/milbenallergie-im-hno-bereich-bedeutung-diagnostik-und-therapieoptionen
#9
Ludger Klimek, Moritz Gröger, Sven Becker
Allergic rhinitis (AR) affects ca. 20% of the population. Approximately one third of patients affected by AR are suffering from perennial rhinitis due to mite allergy. Perennial rhinitis is the form of the disease that is most frequently associated with other allergy-related comorbidities such as asthma and atopic dermatitis, sleep disorders, chronic sinusitis, eustachian tube dysfunction and others.The often non-specific symptoms and the insidious course may lead to misinterpretations in diagnosing the disease...
January 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29295722/clinical-analysis-of-hypersensitivity-reactions-to-oxaliplatin-among-colorectal-cancer-patients
#10
Yuping Shen, Chunyan Li, Weixing Liu, Wei Mao, Hong Qian, Hui Wang, Qing Xu
The study investigated the characteristics of oxaliplatin-induced hypersensitivity reactions (HSR) and evaluated the efficacy of premedication for controlling HSR among colorectal cancer patients. A retrospective study was performed on the clinical records of 291 patients with colorectal cancer in the Tenth People's Hospital of Shanghai from January 2008 and January 2016. Patients who experienced hypersensitivity reactions to oxaliplatin were compared with those who did not. A total of 291 colorectal cancer patients received oxaliplatin, with 39 (13...
January 2, 2018: Oncology Research
https://www.readbyqxmd.com/read/29291397/the-brazilian-portuguese-version-of-the-pediatric-trigger-toolkit-is-applicable-to-measure-the-occurrence-of-adverse-drug-events-in-brazilian-pediatric-inpatients
#11
Lunara Teles Silva, Ana Carolina Figueiredo Modesto, Renato Rocha Martins, Gabriela Guimarães Bessa, Flavio Marques Lopes
OBJECTIVE: To describe the process of translation, adaptation, and validation of the Brazilian Portuguese version of the Pediatric Trigger Toolkit: Measuring Adverse Drug Events in the Children's Hospital. METHODS: The validation process for the research instrument was carried out in five steps: (I) translation from English into Brazilian Portuguese by two independent translators; (II) synthesis of the translated versions; (III) adaptation of the triggers to the Brazilian context using a modified Delphi method carried out in two rounds; (IV) application of the research instrument in the review of 240 hospitalizations during 2014; and (V) back-translation from Brazilian Portuguese to English...
December 29, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29279438/-rotational-isomers-of-diphenhydramine
#12
Matsue Ebitani, Toshiaki Ebitani
  Diphenhydramine(DP), an antihistaminic agent, may become colored and daker or more fluorescent during storage. Herein, we spectroscopically examined the causes of this phenomenon under various DP storage conditions and durations. The infrared vibration-rotation spectrum shows multiple Gauche (G )-type conformers with different intramolecular n→π* interaction strengths. The splitting pattern of the dimethylamino group protons in the 1H-NMR spectrum indicates that DP is mainly in the G-type with a small portion in the Trans(T)-type...
December 27, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29278624/allergic-reactions-and-anesthesia
#13
Danijela Glibo Bevanda, Marko Čačić, Slobodan Mihaljević, Mateo Bevanda, Ante Bogut, Maja Karin
The diagnosis of allergic reactions during anesthesia is difficult. For example, cardio-respiratory symptoms may be due to the accompanying pharmacological effects of anesthetics and poor interpretation of the reaction during anesthesia. It is important to distinguish whether a real allergic reaction has occurred. Accidents with anesthetics and muscle relaxants are observed more often than we expect. Proper anaphylaxis rarely occurs during anesthesia (1: 20000). Muscle relaxants are the most common causes, followed by latex, chlorhexidine, antibiotics and opioids...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29273134/reliability-of-allergy-skin-testing
#14
Maria Shtessel, Jody Tversky
BACKGROUND: Percutaneous allergen skin testing remains an established benchmark for diagnosing atopic disease. The reliability of skin testing depends greatly on the performance of allergen extracts used, methods used, and the presence of antihistamine medications. OBJECTIVE: To determine the differential effect of cetirizine on 2 different concentrations of histamine control solution and 5 common allergens used for percutaneous skin testing. METHODS: Twelve individuals underwent skin testing with histamine (1 and 6 mg/mL), control diluent, and 5 common aeroallergens...
January 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29273103/emerging-unconventional-therapies-for-alopecia-areata
#15
Natasha Atanaskova Mesinkovska
Alopecia areata is a prevalent autoimmune skin disease with no cure or indicated treatment options. In the absence of an approved treatment, some patients are eager to try unconventional therapies, despite the very limited research evaluating their safety and efficacy. Recently emerging unconventional therapies for alopecia areata discussed include antihistamines, cryotherapy, and low-dose naltrexone.
January 2018: Journal of Investigative Dermatology. Symposium Proceedings
https://www.readbyqxmd.com/read/29260784/-the-role-of-local-immunotherapy-in-the-treatment-of-the-patients-presenting-with-virus-associated-allergic-rhinitis
#16
N S Tataurshchikova, B Sangidorzh
The objective of the present study was to evaluate the clinical effectiveness of intranasal immunotherapy with the use of сycloferon in the patients presenting with seasonal virus-associated allergic rhinitis during the period of pollination. The results of the treatment of 50 patients with virus-associated allergic rhinitis (i.e. those allergic to the sagebrush pollen) were analyzed. The patients were divided into two groups depending on the therapeutic modality being used. Those comprising the main group (21 patients) received immunotherapy with сycloferon in addition to allergen-specific immunotherapy (by sublingual administration)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29260783/-possibilities-of-azelastine-in-the-treatment-of-chronic-rhinitis
#17
D S Smirnov, O M Kurbacheva
There is considered modern classification of rhinitis and the accents in diagnostic and therapeutic approaches to patients with this disease are indicated, as well as the possibilities of using topical intranasal antihistamines in the treatment of allergic, vasomotor and medicamentous rhinitis.
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29249139/omalizumab-for-refractory-chronic-spontaneous-urticaria-during-concurrent-immunomodulatory-therapy-for-multiple-sclerosis
#18
N Syrigos, D Grapsa, E Syrigou
Data derived from previous clinical trials and real-life studies have shown that omalizumab may represent an effective third-line treatment option for patients with chronic spontaneous urticaria (CSU) refractory to standard antihistamine treatment. Nevertheless, the safety and efficacy of omalizumab treatment for CSU, when administered concurrently with other immunomodulatory agents remains largely unknown. We herein present the case of a female patient with relapsing-remitting multiple sclerosis (RRMS), under treatment with interferon beta-1a, azathioprine and gabapentin, who was successfully treated with omalizumab for refractory CSU...
November 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29249138/transient-hair-loss-in-patients-with-chronic-spontaneous-urticaria-treated-with-omalizumab
#19
M Noshela Ghazanfar, S F Thomsen
Omalizumab (anti-IgE) is used as add-on therapy for antihistamine refractory chronic urticaria patients. The most commonly reported adverse effects were headache, arthralgia, upper respiratory infections, fatigue, nausea and injection-site reactions. However, lately a few cases of hair loss have been reported. We describe a case of transient hair loss in a young female patient after initiating treatment with omalizumab. Despite this side effect, the patient continued with omalizumab treatment for 10 months with good effect...
November 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29249111/-hereditary-angioedema-by-c1-inhibitor-deficit-diagnostic-and-therapeutic-challenges-case-report
#20
Álvaro José Mayorga, Gerardo José Ayestas-Moreno
BACKGROUND: Hereditary angioedema is a disease which manifests itself with episodes of spontaneous edema on skin, mucosal and airway. Treatment includes acute and prophylactic approach to minimize the attacks and severity. In many parts of the world, androgen derivatives, antifibrinolytic and fresh frozen plasma are the therapies available for prophylaxis. CLINICAL REPORT: 16 years old teenager of without history of immune decease, has in the course of 1-year repetitive episodes of painless, non-pruritic angioedema, does not respond to antihistamine therapy, corticosteroids or adrenaline; fresh frozen plasma is applied in 1 occasion exacerbating episode with severity...
October 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
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