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https://www.readbyqxmd.com/read/28346866/prevalence-and-potential-risk-factors-for-bartonella-infection-in-tunisian-stray-dogs
#1
Jaber Belkhiria, Bruno B Chomel, Taoufik Ben Hamida, Rickie W Kasten, Matthew J Stuckey, Drew A Fleischman, Mary M Christopher, Henri-Jean Boulouis, Thomas B Farver
Bartonellae are blood-borne and vector-transmitted pathogens, some are zoonotic, which have been reported in several Mediterranean countries. Transmission from dogs to humans is suspected, but has not been clearly demonstrated. Our objectives were to determine the seroprevalence of Bartonella henselae, Bartonella vinsonii subsp. berkhoffii, Bartonella clarridgeiae, and Bartonella bovis (as a proxy for Candidatus Bartonella merieuxii) in stray dogs from Tunisia, identify the Bartonella species infecting the dogs and evaluate potential risk factors for canine infection...
March 27, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28346729/comparison-of-the-safety-of-electrotome-harmonic-scalpel-and-ligasure-for-management-of-thyroid-surgery
#2
Xiaodong Yang, Jian Cao, Yichao Yan, Fangfang Liu, Tao Li, Long Han, Chunxiang Ye, Shuying Zheng, Shan Wang, Yingjiang Ye, Kewei Jiang
BACKGROUND: Energy-based surgical devices, including electrotome, the Harmonic scalpel, and LigaSure, have been widely applied in thyroid surgery, although a comparison of their safety and efficacy has not been reported yet. In this study, we investigated the feasibility of using hemostatic energy-based surgical devices during thyroid surgery in a canine model. METHODS: Twenty-four beagle dogs were randomly divided into the following groups: electrotome (30 kW), electrotome (15 kW), the Harmonic scalpel (output level 3), and LigaSure (middle gear)...
March 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28346702/evaluation-of-the-effects-of-time-temperature-and-specimen-storage-on-in-vitro-lactate-concentrations-in-healthy-dogs
#3
Colin F Reich, Jonathan F Bach, Julie M Walker
BACKGROUND: Lactate concentrations increase significantly under certain storage conditions, except for when glycolysis-arresting agents are used. Evaluation of time and storage conditions on heparinized whole blood lactate concentrations without glycolysis-arresting agents have not been evaluated in dogs. OBJECTIVES: The purpose of the study was to determine the effects of preanalytic storage conditions on the in vitro concentration of lactate in heparinized canine venous blood specimens...
March 27, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28346125/canine-neutrophil-extracellular-traps-enhance-clot-formation-and-delay-lysis
#4
Unity Jeffery, Dana N LeVine
Autoimmune diseases increase the risk of thrombosis. Neutrophil extracellular traps (NETs) are webs of DNA and protein that may mediate thrombosis in autoimmune diseases. Human and murine studies show NET-releasing neutrophils within a thrombus promote its growth, but it is unclear to what extent NET fragments released into circulation during inflammation are prothrombotic. This study hypothesized that canine NETs promote clot formation and impair lysis even in the absence of neutrophils. NETs were prepared from PMA-stimulated neutrophils and added to fibrinogen and thrombin or to recalcified pooled canine platelet-poor plasma, tissue factor, and tissue plasminogen activator...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346124/pax8-napsin-a-and-cd10-as-immunohistochemical-markers-of-canine-renal-cell-carcinoma
#5
Tyler J Peat, Elijah F Edmondson, Margaret A Miller, Dee M DuSold, José A Ramos-Vara
Pax8, napsin A, and CD10 are useful immunohistochemical markers of human renal cell carcinoma (RCC); however, their diagnostic utility in canine RCC is unclear. Forty formalin-fixed paraffin-embedded renal cell carcinomas from dogs (15 papillary, 12 solid, and 13 tubular) and 10 metastases were evaluated for expression of Pax8, napsin A, and CD10. Thirty-nine (98%), 24 (60%), and 19 (50%) tumors expressed Pax8 (nuclear labeling), napsin A (cytoplasmic labeling), and CD10 (cytoplasmic and membranous labeling), respectively...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346123/panfungal-polymerase-chain-reaction-for-identification-of-fungal-pathogens-in-formalin-fixed-animal-tissues
#6
Courtney Meason-Smith, Erin E Edwards, Caitlin E Older, Mackenzie Branco, Laura K Bryan, Sara D Lawhon, Jan S Suchodolski, Gabriel Gomez, Joanne Mansell, Aline Rodrigues Hoffmann
Identification of fungal organisms often poses a problem for pathologists because the histomorphology of some fungal organisms is not specific, fresh tissues may not be available, and isolation and identification in culture may take a long time. The purpose of this study was to validate the use of panfungal polymerase chain reaction (PCR) to identify fungal organisms from formalin-fixed paraffin-embedded (FFPE) tissues. Formalin-fixed paraffin-embedded curls were tested from 128 blocks containing canine, feline, equine, and bovine tissues with cutaneous, nasal, pulmonary, and systemic fungal infections, identified by the presence of fungi in histologic sections...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346050/perception-of-canine-welfare-concerns-among-veterinary-students-practitioners-and-behavior-specialists-in-spain
#7
Isabel Luño, Jorge Palacio, Sylvia García-Belenguer, Ángela González-Martínez, Belén Rosado
Veterinarians are well placed to supervise and ensure canine welfare. However, the perception of animal welfare among veterinarians may vary depending on the level of training and professional practice, including the specialization in animal behavior and welfare. The aim of this study was to survey the perception of canine welfare among veterinarians, including students, practitioners, and behavior specialists. A scale-based questionnaire including 12 issues affecting canine welfare was adapted from Yeates and Main and distributed to first-year (n=50) and fifth-year veterinary students (n=50), as well as veterinary practitioners (n=260) and specialists in behavioral medicine (n=50)...
March 27, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28346006/magnetic-resonance-imaging-susceptibility-artifacts-in-the-cervical-vertebrae-and-spinal-cord-related-to-monocortical-screw-polymethylmethacrylate-implants-in-canine-cadavers
#8
Brian G Jones, Geoffrey T Fosgate, Eric M Green, Amy M Habing, Bianca F Hettlich
OBJECTIVE To characterize and compare MRI susceptibility artifacts related to titanium and stainless steel monocortical screws in the cervical vertebrae and spinal cord of canine cadavers. SAMPLE 12 canine cadavers. PROCEDURES Cervical vertebrae (C4 and C5) were surgically stabilized with titanium or stainless steel monocortical screws and polymethylmethacrylate. Routine T1-weighted, T2-weighted, and short tau inversion recovery sequences were performed at 3.0 T. Magnetic susceptibility artifacts in 20 regions of interest (ROIs) across 4 contiguous vertebrae (C3 through C6) were scored by use of an established scoring system...
April 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28346000/assessment-of-the-potential-efficacy-of-blind-perineural-injection-techniques-for-blockade-of-the-saphenous-obturator-and-lateral-cutaneous-femoral-nerves-in-dog-cadavers
#9
Diego F Echeverry-Bonilla, Jessica T Pelaez, Edwin F Buriticá, Francisco G Laredo
OBJECTIVE To evaluate the potential efficacy of blind perineural injection techniques to provide nerve blockade of the saphenous, obturator, and lateral cutaneous femoral nerves by assessing the distribution along those nerves of 3 volumes of an injected staining solution in dog cadavers. ANIMALS 18 canine cadavers. PROCEDURES The anatomic characteristics of the target nerves were evaluated by dissection in 3 cadavers. The saphenous nerve was located by the use of superficial anatomic landmarks and a loss-of-resistance test...
April 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28345997/evaluation-of-a-new-method-to-determine-the-tibial-tuberosity-advancement-distance-required-to-reduce-the-patellar-tendon-tibial-plateau-angle-to-90%C3%A2-with-the-modified-maquet-technique-in-dogs
#10
Paul Pillard, Veronique Livet, Quentin Cabon, Camille Bismuth, Juliette Sonet, Denise Remy, Didier Fau, Claude Carozzo, Eric Viguier, Thibaut Cachon
OBJECTIVE To assess use of a new radiographic method to determine the distance by which the tibial tuberosity should be advanced to reduce the patellar tendon-tibial plateau angle (PTA) to 90° by means of the modified Maquet technique (MMT) in dogs. SAMPLE 24 pelvic limbs from 12 adult medium-sized to large-breed canine cadavers. PROCEDURES Radiographs of stifle joints at 135° extension in true lateral position were used to determine tibial tuberosity advancement distances for use in the MMT. A method was devised to incorporate the planned osteotomy axis; distal patellar translations of 0, 3, 5, or 10 mm; and advancement cage implant application level along the osteotomy site in advancement planning measurements...
April 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28345758/biodegradable-gelatin-beta-tricalcium-phosphate-sponges-incorporating-recombinant-human-fibroblast-growth-factor-2-for-treatment-of-recession-type-defects-a-split-mouth-study-in-dogs
#11
A Shujaa Addin, T Akizuki, S Hoshi, T Matsuura, T Ikawa, S Fukuba, M Matsui, Y Tabata, Y Izumi
BACKGROUND AND OBJECTIVE: Tissue engineering by using recombinant human (rh) growth factor technology may offer a promising therapeutic approach for treatment of gingival recession. Fibroblast growth factor-2 (FGF-2) has shown the ability to promote periodontal regeneration. Gelatin/beta-tricalcium phosphate (gelatin/β-TCP) sponges have been developed to control the release of growth factors. The present study evaluated the periodontal regenerative efficacy of rhFGF-2 by comparing gelatin/β-TCP sponges incorporated with rhFGF-2 to the scaffolds alone in artificially created recession-type defects in dogs...
March 27, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28345412/effect-of-glucosamine-sulfate-on-osteoarthritis-in-the-cruciate-deficient-canine-model-of-osteoarthritis
#12
Wolfram Wenz, Christian Hornung, Christopher Cramer, Malte Schroeder, Michael Hoffmann
Objective Osteoarthritis (OA) is a major cause of musculoskeletal pain and disability worldwide. The investigation of disease-modifying treatment options for OA has become an important aspect of orthopedic care. To assess the effect of intra-articular and oral glucosamine sulfate (GS) versus placebo on osteoarthritis in a canine model. Materials In this randomized, placebo-controlled, double-blinded study, OA was induced by anterior cruciate ligament transection (ACLT) according to the Pond-Nuki model in 32 canines...
April 2017: Cartilage
https://www.readbyqxmd.com/read/28344992/mechanism-of-deletion-removing-all-dystrophin-exons-in-a-canine-model-for-dmd-implicates-concerted-evolution-of-x-chromosome-pseudogenes
#13
D Jake VanBelzen, Alock S Malik, Paula S Henthorn, Joe N Kornegay, Hansell H Stedman
Duchenne muscular dystrophy (DMD) is a lethal, X-linked, muscle-wasting disorder caused by mutations in the large, 2.4-Mb dystrophin gene. The majority of DMD-causing mutations are sporadic, multi-exon, frameshifting deletions, with the potential for variable immunological tolerance to the dystrophin protein from patient to patient. While systemic gene therapy holds promise in the treatment of DMD, immune responses to vectors and transgenes must first be rigorously evaluated in informative preclinical models to ensure patient safety...
March 17, 2017: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/28344412/clinical-and-hematobiochemical-response-in-canine-monocytic-ehrlichiosis-seropositive-dogs-of-punjab
#14
Manasa R Kottadamane, Pritpal Singh Dhaliwal, Lachhman Das Singla, Baljinder Kumar Bansal, Sanjeev Kumar Uppal
AIM: As in India especially, the Punjab state sero-prevalence and distribution of ehrlichiosis in relation to clinico-hematobiochemical response remains largely unexplored. Thus, this study was designed to determine the prevalence of vector (tick)-borne tropical canine pancytopenia caused by Ehrlichia canis through enzyme labeled ImmunoComb(®) (IC) assay in dogs from in and around Ludhiana, Punjab. Correlation of prevalence was made with various clinico-hematobiochemical parameters. MATERIALS AND METHODS: Seroprevalence study was carried out using IC(®) test kit (Biogal, Galed Labs)...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28343157/isolated-unilateral-upper-alveolar-numbness-in-silent-sinus-syndrome
#15
Hung Tuan Lau, Keng Hua Lim
We present a case of a 59-year-old man with left upper alveolar numbness of 2 years' duration in the absence of sinonasal symptoms. On physical examination, he demonstrated mild left facial asymmetry and diminished sensation of his left upper alveolus from the left second upper incisor to first canine. CT imaging revealed chronic sinusitis changes of the left maxillary sinus, with reduced volume and depressed anterior wall. The patient underwent functional endoscopic sinus surgery to re-establish maxillary sinus ventilation...
March 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28342271/more-bark-than-bite-comparative-studies-are-needed-to-determine-the-importance-of-canine-zoonoses-in-aboriginal-communities-a-critical-review-of-published-research
#16
REVIEW
F Smout, L Schrieber, R Speare, L F Skerratt
The objective of this review was to identify and critique over forty years of peer-reviewed literature concerned with the transmission of canine zoonoses to Aboriginal people and determine the zoonotic organisms documented in dogs in Australian Aboriginal communities. A systematic literature search of public health, medical and veterinary databases identified 19 articles suitable for critical appraisal. Thirteen articles documented the occurrence of recognized zoonotic organisms in dogs in Aboriginal communities, including Toxocara canis, Dirofilaria immitis, Streptococcus dysgalactiae, Rickettsia felis, Sarcoptes scabiei and Giardia...
March 25, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28339756/molecular-diagnosis-of-pneumocystis-pneumonia-in-dogs
#17
Patrizia Danesi, Silvia Ravagnan, Lynelle R Johnson, Tommaso Furlanello, Adelaide Milani, Patricia Martin, Susan Boyd, Matthew Best, Bradley Galgut, Peter Irwin, Paul J Canfield, Mark B Krockenberger, Catriona Halliday, Wieland Meyer, Richard Malik
Pneumocystis pneumonia (PCP) is a life-threatening fungal disease that can occur in dogs. The aim of this study was to provide a preliminary genetic characterisation of Pneumocystis carinii f.sp.'canis' (P. canis) in dogs and thereby develop a reliable molecular protocol to definitively diagnose canine PCP. We investigated P. canis in a variety of lung specimens from dogs with confirmed or strongly suspected PCP (Group 1, n = 16), dogs with non-PCP lower respiratory tract problems (Group 2, n = 65) and dogs not suspected of having PCP or other lower respiratory diseases (Group 3, n = 11)...
February 23, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28339469/non-invasive-evaluation-of-muscle-disease-in-the-canine-model-of-duchenne-muscular-dystrophy-by-electrical-impedance-myography
#18
Chady H Hakim, Alex Mijailovic, Thais B Lessa, Joan R Coates, Carmen Shin, Seward B Rutkove, Dongsheng Duan
Dystrophin-deficient dogs are by far the best available large animal models for Duchenne muscular dystrophy (DMD), the most common lethal childhood muscle degenerative disease. The use of the canine DMD model in basic disease mechanism research and translational studies will be greatly enhanced with the development of reliable outcome measures. Electrical impedance myography (EIM) is a non-invasive painless procedure that provides quantitative data relating to muscle composition and histology. EIM has been extensively used in neuromuscular disease research in both human patients and rodent models...
2017: PloS One
https://www.readbyqxmd.com/read/28339384/evaluation-of-the-most-frequently-prescribed-extemporaneously-compounded-veterinary-medications-at-a-large-independent-community-pharmacy
#19
Adel H Karara, Ryan Hines, Zehra Demir, Bethran Nnorom, Robert Horsey, Geoffrey Twigg
Extemporaneous drug formulation is essential to provide optimal pharmaceutical care to veterinary patients. The need for this is exacerbated by the fact that commercially produced veterinary-specific products, without a human indication, require specialty veterinary manufacturing facilities and a new animal drug application process to gain marketing approval. This study examined the prescription patterns of extemporaneously compounded veterinary preparations in the compounding department at a large independent community pharmacy...
November 2016: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28339112/canine-penile-hirudiniasis-an-unusual-cause-of-bleeding-from-the-prepuce
#20
H Salari Sedigh, M Rajabioun
No abstract text is available yet for this article.
March 24, 2017: Journal of Small Animal Practice
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