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https://www.readbyqxmd.com/read/28430887/measurement-of-forces-and-moments-around-the-maxillary-arch-for-treatment-of-a-simulated-lingual-incisor-and-high-canine-malocclusion-using-straight-and-mushroom-archwires-in-fixed-lingual-appliances
#1
Brandon Owen, Geoffry Gullion, Giseon Heo, Jason P Carey, Paul W Major, Dan L Romanyk
Introduction: An Orthodontic SIMulator (OSIM) was used to investigate the propagation of forces and moments around a simulated archform for a gingival displaced canine and lingual displaced lateral incisor using fixed lingual orthodontic appliances. Methods: In-Ovation L self-ligating lingual brackets were bonded to anatomically shaped teeth on the OSIM, and the teeth were positioned such that a G4 NiTi 0.016" large maxillary mushroom archwire could be ligated in passive position...
April 20, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28429414/evaluation-of-t2-weighted-versus-short-tau-inversion-recovery-sagittal-sequences-in-the-identification-and-localization-of-canine-intervertebral-disc-extrusion-with-low-field-magnetic-resonance-imaging
#2
Daniel Housley, Abby Caine, Giunio Cherubini, Olivier Taeymans
Sagittal T2-weighted sequences (T2-SAG) are the foundation of spinal protocols when screening for the presence of intervertebral disc extrusion. We often utilize sagittal short-tau inversion recovery sequences (STIR-SAG) as an adjunctive screening series, and experience suggests that this combined approach provides superior detection rates. We hypothesized that STIR-SAG would provide higher sensitivity than T2-SAG in the identification and localization of intervertebral disc extrusion. We further hypothesized that the parallel evaluation of paired T2-SAG and STIR-SAG series would provide a higher sensitivity than could be achieved with either independent sagittal series when viewed in isolation...
April 20, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28429096/differences-in-problem-solving-between-canid-populations-do-domestication-and-lifetime-experience-affect-persistence
#3
Lauren Brubaker, Sandipan Dasgupta, Debottam Bhattacharjee, Anindita Bhadra, Monique A R Udell
Past research has suggested that a variety of factors, phylogenetic and ontogenetic, play a role in how canines behave during problem-solving tasks and the degree to which the presence of a human influences their problem-solving behaviour. While comparisons between socialized wolves and domestic dogs have commonly been used to tease apart these predictive factors, in many cases a single dog population, often pets, have been used for these comparisons. Less is understood about how different populations of dogs may behave when compared with wolves, or with each other, during an independent problem-solving task...
April 20, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28428308/genome-sequence-of-canine-adenovirus-type-1-isolated-from-a-wolf-canis%C3%A2-lupus-in-southern-italy
#4
Federica Pizzurro, Maurilia Marcacci, Guendalina Zaccaria, Massimiliano Orsini, Francesca Cito, Alfonso Rosamilia, Ludovica Di Renzo, Daniela Malatesta, Daria Di Sabatino, Alessio Lorusso
Canine adenovirus type 1 (CAdV-1), a DNA virus of the family Adenoviridae, causes infectious canine hepatitis, a highly contagious disease primarily affecting canids. In this report, we describe the isolation and whole-genome sequence of a CAdV-1 isolate from the liver of a free-ranging wolf (Canis lupus).
April 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28427962/first-report-of-a-rickettsia-asembonensis-related-infecting-fleas-in-brazil
#5
Arannadia Barbosa Silva, Vinicius Figueiredo Vizzoni, Andréa Pereira Costa, Francisco Borges Costa, Jonas Moraes-Filho, Marcelo Bahia Labruna, Gilberto Salles Gazêta, Rita de Maria Seabra Nogueira
The present study was performed in a non-endemic area for spotted fever (SF) in Imperatriz microregion, state of Maranhão, Brazil. Blood samples and ectoparasites were collected from 300 dogs of the Imperatriz microregion. Canine serum samples were tested individually by indirect immunofluorescence assay (IFA), using five Rickettsia isolates from Brazil. Antibodies reactive to at least one of the five species of Rickettsia were detected in 1.6% of the dogs (5/300). These sera were considered reactive to Rickettsia rickettsii and Rickettsia amblyommatis or very closely related species...
April 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28427438/canine-%C3%AE-defensin-1-cbd1-gene-as-a-possible-marker-for-leishmania-infantum-infection-in-dogs
#6
Lidiane Gomes da Silva, César Raimundo Lima Costa-Júnior, Carlos Alberto Santiago Figueiredo-Júnior, Tereza Cristina Leal-Balbino, Sergio Crovella, Domenico Otranto, Valdir de Queiroz Balbino, Filipe Dantas-Torres
BACKGROUND: Canine leishmaniasis caused by Leishmania infantum is a parasitic disease of great veterinary significance. Some dogs infected by L. infantum may mount a strong cellular immune response and clear the infection, while others may respond with exaggerated antibody production against the parasite and develop an overt disease, which may be fatal, if left untreated. The initial factors triggering the polarization of the immune response towards a predominantly T-helper 1 or T-helper 2 cytokines, as well as the markers of resistance and susceptibility to L...
April 20, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28427401/ki-67-protein-expression-and-tumor-associated-inflammatory-cells-macrophages-and-mast-cells-in-canine-colorectal-carcinoma
#7
M Woldemeskel, I Hawkins, L Whittington
BACKGROUND: Ki67 index, tumor associated macrophages (TAMs) and mast cells (MCs) are associated with malignancies in animal and human neoplasms including colorectal carcinomas (CRC). This has not been assessed in canine CRC. Given similar genetic abnormalities between human and canine CRC, we assessed Ki-67 and mitotic indices, TAMs and MC count (MCC) in canine CRC (n = 17). TAMs and MCC were compared with those in adenomas (n = 13) and control (n = 9). RESULTS: Ki-67 index in CRC (17...
April 20, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28426554/barking-up-the-right-tree-advancing-our-understanding-and-treatment-of-lymphoma-with-a-spontaneous-canine-model
#8
Dania Villarnovo, Angela L McCleary-Wheeler, Kristy L Richards
PURPOSE OF REVIEW: Spontaneous lymphoma in pet dogs is increasingly recognized as an ideal model for studying the disease in humans and for developing new targeted therapeutics for patients. Increasing interest by funding agencies, the private sector, and multidisciplinary academic collaborations between different disciplines and sectors now enables large knowledge gaps to be addressed and provides additional proof-of-concept examples to showcase the significance of the canine model. RECENT FINDINGS: The current review addresses the rationale for a canine lymphoma model including the valuable role it can play in drug development, serving as a link between mouse xenograft models and human clinical trials and the infrastructure that is now in place to facilitate these studies...
April 19, 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/28426425/the-role-of-domestic-dogs-in-the-transmission-of-zoonotic-helminthes-in-a-rural-area-of-mekong-river-basin
#9
Marcello Otake Sato, Megumi Sato, Tippayarat Yoonuan, Tiengkham Pongvongsa, Surapol Sanguankiat, Sengchanh Kounnavong, Wanna Maipanich, Yuichi Chigusa, Kazuhiko Moji, Jitra Waikagul
Dogs have been bred since ancient times for companionship, hunting, protection, shepherding and other human activities. Some canine helminth parasites can cause significant clinical diseases in humans as Opisthorchis viverrini causing cholangiocarcinoma in Southeast Asian Countries. In this study, socio-cultural questionnaire, canine parasitological analysis, necropsy, parasite molecular confirmation and dog roaming data were evaluated in Savannakhet, Lao-PDR, a typical Mekong Basin area. Dog owners comprised 48...
June 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28426340/a-novel-recombinant-canine-adenovirus-type-1-detected-from-acute-lethal-cases-of-infectious-canine-hepatitis
#10
Magdelene Wong, Lucy Woolford, Noor Haliza Hasan, Farhid Hemmatzadeh
In this study, canine adenoviruses (CAdVs) from two acute fatal cases of infectious canine hepatitis (ICH) were analyzed using molecular detection and sequencing of the pVIII, E3, and fiber protein genes. Pathological findings in affected dogs were typical for CAdV-1 associated disease, characterized by severe centrilobular to panlobular necrohemorrhagic hepatitis and the development of disseminated intravascular coagulation in the terminal stages of disease. Comparison of partial genome sequences revealed that although these newly detected viruses mainly had CAdV-1 genome characteristics, their pVIII gene was more similar to that of CAdV-2...
April 20, 2017: Viral Immunology
https://www.readbyqxmd.com/read/28424777/influence-of-cellular-composition-and-exogenous-activation-on-growth-factor-and-cytokine-concentrations-in-canine-platelet-rich-plasmas
#11
Samuel P Franklin, Kate E Birdwhistell, Alena Strelchik, Bridget C Garner, Benjamin M Brainard
OBJECTIVE: The purposes of this study were to (1) evaluate correlations among platelet, leukocyte, growth factor, and cytokine concentrations in canine platelet-rich plasmas (PRPs) produced from five different canine PRP-concentrating systems and (2) compare the effects of different activation protocols on platelet activation and growth factor release from one of these PRPs. METHODS: PRP was made using blood from 15 dogs and each of 5 different PRP systems in a cross-over design...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28424536/rifapentine-linezolid-loaded-plga-microspheres-for-interventional-therapy-of-cavitary-pulmonary-tuberculosis-preparation-and-in-vitro-characterization
#12
Jieyun Huang, Zhi Chen, Ying Li, Li Li, Guangyu Zhang
In this study, we aimed to design controlled-release microspheres for the treatment of cavitary pulmonary tuberculosis (TB) for solving the issues of poor drug delivery and short duration maintained at effective drug concentration during bronchoscopic interventional therapy. We fabricated rifapentine-linezolid-loaded poly(lactic acid-co-glycolic acid) microspheres (RLPMs) using the oil-in-water emulsion solvent evaporation method and assessed their in vitro release as well as the bronchial mucosal retention characteristics...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28424002/enzyme-linked-immunosorbent-assays-for-coproantigen-detection-of-ancylostoma-caninum-and-toxocara-canis-in-dogs-and-toxocara-cati-in-cats
#13
David A Elsemore, Jinming Geng, Jennifer Cote, Rita Hanna, Araceli Lucio-Forster, Dwight D Bowman
We report the development and field validation of 2 ELISAs for the detection of Ancylostoma caninum or Toxocara canis coproantigens in the feces of dogs with experimental and natural infections, and evidence of cross-reactivity with respective feline counterparts. A. caninum-specific coproantigens were detected in feces of experimentally infected dogs starting at 9 d post-infection (dpi), whereas eggs were not seen until 23 dpi. T. canis-specific coproantigens were detected in 3 of 5 experimentally infected dogs by 31 dpi, and 4 of the 5 animals by 38 dpi...
April 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28421625/factors-affecting-platelet-concentration-in-platelet-concentrates-from-canine-blood-donors
#14
J S Raleigh, K E Jandrey, J Burges, M S Kent
BACKGROUND: Physiologic factors in dogs that might contribute to enhanced platelet yield in platelet concentrates (PCs) are largely unknown. OBJECTIVE: To determine whether individual differences in weight, age, preprocessing blood chemistry, and CBC variables predict the final platelet concentrations in PCs. Our hypotheses were (1) increased lipemic indices would be positively associated with increased platelet concentrations in PCs and (2) increased preprocessing platelet concentrations would be associated with higher platelet concentrations in the PCs...
April 19, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28421298/dog-rivalry-impacts-following-behavior-in-a-decision-making-task-involving-food
#15
Christy L Hoffman, Malini Suchak
Dogs learn a great deal from humans and other dogs. Previous studies of socially influenced learning between dogs have typically used a highly trained demonstrator dog who is unfamiliar to the observer. Because of this, it is unknown how dynamics between familiar dogs may influence their likelihood of learning from each other. In this study, we tested dogs living together in two-dog households on whether individual dogs' rivalry scores were associated with performance on a local enhancement task. Specifically, we wanted to know whether dog rivalry impacted whether an observer dog would approach a plate from which a demonstrator dog had eaten all available food, or whether the observer dog would approach the adjacent plate that still contained food...
April 18, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28421186/cost-description-and-comparative-cost-efficiency-of-post-exposure-prophylaxis-and-canine-mass-vaccination-against-rabies-in-n-djamena-chad
#16
Rolande Mindekem, Monique Sarah Lechenne, Kemdongarti Service Naissengar, Assandi Oussiguéré, Bidjeh Kebkiba, Daugla Doumagoum Moto, Idriss Oumar Alfaroukh, Laurent Tinoanga Ouedraogo, Sahidou Salifou, Jakob Zinsstag
Rabies claims approximately 59,000 human lives annually and is a potential risk to 3.3 billion people in over 100 countries worldwide. Despite being fatal in almost 100% of cases, human rabies can be prevented by vaccinating dogs, the most common vector, and the timely administration of post-exposure prophylaxis (PEP) to exposed victims. For the control and prevention of human rabies in N'Djamena, the capital city of Chad, a free mass vaccination campaign for dogs was organized in 2012 and 2013. The campaigns were monitored by parallel studies on the incidence of canine rabies based on diagnostic testing of suspect animals and the incidence of human bite exposure recorded at selected health facilities...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28419841/buffered-1-lidocaine-with-epinephrine-can-be-as-effective-as-nonbuffered-2-lidocaine-with-epinephrine-for-maxillary-field-block
#17
James A Phero, Victor T Warren, Anson G Fisher, Eric M Rivera, Pooja T Saha, Glenn Reside, Ceib Phillips, Raymond P White
PURPOSE: Buffering local anesthetics with epinephrine (Epi) offers clinicians options not often considered. This study assessed outcomes for pulpal anesthesia, pain on injection, and time to midface numbness for buffered 1% lidocaine with 1:100,000 Epi versus nonbuffered 2% lidocaine with 1:100,000 Epi. MATERIALS AND METHODS: In this trial with a randomized, crossover design, buffered 1% lidocaine was compared with nonbuffered 2% lidocaine. Participants were adult volunteers who served as their own controls...
March 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28419683/geographical-differences-in-survival-of-dogs-with-non-hodgkin-lymphoma-treated-with-a-chop-based-chemotherapy-protocol
#18
H Wilson-Robles, C M Budke, T Miller, N Dervisis, A Novosad, Z Wright, D H Thamm, K Vickery, K Burgess, M Childress, J Lori, C Saba, S Rau, M Silver, G Post, K Reeds, S Gillings, S Schleis, T Stein, B Brugmann, C DeRegis, O Smrkovski, J Lawrence, T Laver
BACKGROUND: In humans geographical differences in the incidence and presentation of various cancers have been reported. However, much of this information has not been collected in veterinary oncology. AIM: The purpose of this study was to determine if a geographic difference in progression free survival exists for dogs with lymphoma treated within the US. MATERIALS AND METHODS: Medical records of 775 cases of canine lymphoma from 3 US regions (west, south and north), treated with CHOP chemotherapy, were retrospectively evaluated...
April 17, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28419676/efficacy-of-dacarbazine-as-a-rescue-agent-for-histiocytic-sarcoma-in-dogs
#19
K A Kezer, L G Barber, S H Jennings
BACKGROUND: Canine histiocytic sarcoma (HS) is an aggressive neoplasm that is generally associated with a poor prognosis. CCNU is considered first-line medical therapy, although the majority of dogs ultimately develop progressive disease. The objective of this study was to evaluate the efficacy of dacarbazine as a rescue agent for HS. MATERIALS AND METHODS: Medical records of dogs diagnosed with HS that received at least one dose of dacarbazine were reviewed. Information collected and analyzed included signalment, disease distribution, treatment history, dacarbazine treatments (including dose, interval and total number of cycles), adverse events, and response to treatment...
April 17, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28419635/canine-histiocytic-sarcoma-presenting-as-a-target-lesion-on-brain-magnetic-resonance-imaging-and-as-a-solitary-pulmonary-mass
#20
Jill Hicks, Renee Barber, Bronwen Childs, Shannon Gm Kirejczyk, Elizabeth W Uhl
A 6-year-old spayed female miniature schnauzer presented with generalized seizures and progressive multifocal intracranial neurologic disease. Thoracic radiographs and computed tomography (CT) revealed a large solitary pulmonary mass within the right cranial lung lobe. On brain magnetic resonance imaging (MRI), a solitary intraparenchymal mass within the left piriform lobe had a "target" appearance on both pre- and postcontrast sequences. Cerebrospinal fluid was unremarkable and histopathology indicated both masses represented histiocytic sarcoma...
April 17, 2017: Veterinary Radiology & Ultrasound
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