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Viral hepatitis, hepatitis C, hepatitis B, crohn's disease, colitis, drug induced liver disease,

María Rojas-Feria, Manuel Castro, Emilio Suárez, Javier Ampuero, Manuel Romero-Gómez
Abnormal liver biochemical tests are present in up to 30% of patients with inflammatory bowel disease (IBD), and therefore become a diagnostic challenge. Liver and biliary tract diseases are common extraintestinal manifestations for both Crohn's disease and ulcerative colitis (UC), and typically do not correlate with intestinal activity. Primary sclerosing cholangitis (PSC) is the most common hepatobiliary manifestation of IBD, and is more prevalent in UC. Approximately 5% of patients with UC develop PSC, with the prevalence reaching up to 90%...
November 14, 2013: World Journal of Gastroenterology: WJG
C Loras, J P Gisbert, M Mínguez, O Merino, L Bujanda, C Saro, E Domenech, J Barrio, M Andreu, I Ordás, L Vida, G Bastida, F González-Huix, M Piqueras, D Ginard, X Calvet, A Gutiérrez, A Abad, M Torres, J Panés, M Chaparro, I Pascual, M Rodriguez-Carballeira, F Fernández-Bañares, J M Viver, M Esteve
BACKGROUND: There is no information about the frequency of liver dysfunction in patients with inflammatory bowel disease (IBD) treated with immunosuppressants and infected with hepatitis B (HBV) and/or C virus (HCV). AIM: To assess the influence of immunosuppressants on the course of HBV and HCV infection in IBD. METHODS: Patients with IBD with HBV and/or HCV infection from 19 Spanish hospitals were included. Clinical records were reviewed for the type of immunosuppressant used, treatment duration, liver function tests and viral markers before, during and after each immunosuppressant...
October 2010: Gut
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