keyword
MENU ▼
Read by QxMD icon Read
search

Papillary Thyroid Carcinoma

keyword
https://www.readbyqxmd.com/read/28238469/role-of-laminin-332-in-lymph-node-metastasis-of-papillary-thyroid-carcinoma
#1
Kyoung Ho Oh, June Choi, Jeong-Soo Woo, Seung Kuk Baek, Kwang Yoon Jung, Min Ji Koh, Young-Sik Kim, Soon Young Kwon
OBJECTIVE: The invasiveness of papillary thyroid carcinoma (PTC), including the occurrence of cervical lymph node metastasis, is the main determining factors contributing to recurrence and poor prognosis. Laminin 332 is a glycoprotein involved in cell migration and cancer cell invasion into surrounding tissues and is therefore related to poor prognosis in many cancers. Here, we investigated the expression and role of laminin 332 in PTC and examine the possibility that laminin 332 could be involved in the invasiveness of PTC...
February 23, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28237641/sternal-metastasis-as-first-presentation-of-a-well-differentiated-papillary-thyroid-carcinoma
#2
Eleftherios Spartalis, Demetrios Moris, Periklis Tomos
No abstract text is available yet for this article.
February 22, 2017: Surgery
https://www.readbyqxmd.com/read/28236537/efficiency-of-intraoperative-neuromonitoring-on-voice-outcomes-after-thyroid-surgery
#3
Seung-Kuk Baek, Kijeong Lee, Dongju Oh, Sung Hoon Kang, Soon-Young Kwon, Jeong-Soo Woo, Jae-Gu Cho, Kyung Ho Oh, Doh Young Lee, Kwang-Yoon Jung
OBJECTIVE: Voice disturbance is an important problem after thyroidectomy. The aim of this study was to evaluate the efficiency of intraoperative neuromonitoring (IONM) in reducing early phonation change by comparing postoperative voice outcomes. METHODS: The study retrospectively enrolled 68 consecutive female patients who had undergone IONM thyroidectomy for papillary thyroid carcinoma occurring between January 2014 and November 2014. A historical group of 117 similar female patients not receiving IONM thyroidectomy was used as an external control...
February 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28236059/ewsr1-rearrangement-is-a-frequent-event-in-papillary-thyroid-carcinoma-and-in-carcinoma-of-the-thyroid-with-ewing-family-tumor-elements-cefte
#4
G Oliveira, A Polónia, J M Cameselle-Teijeiro, D Leitão, S Sapia, M Sobrinho-Simões, C Eloy
Carcinomas of the thyroid with Ewing family tumor element (CEFTEs) are small-cell thyroid tumors with epithelial differentiation that disclose p63 expression and EWSR1-FLI1 rearrangement, carry a favorable prognosis and may co-exist with papillary thyroid carcinoma (PTC) foci. Two histogenetic hypotheses have been advanced regarding the origin of CEFTEs: arising in PTCs or in solid cell nests (SCN). A total of 3 CEFTEs, 54 PTCs, and 10 SCNs were reviewed, and fluorescence in situ hybridization (FISH) technique was performed in all cases to search for the presence of EWSR1 rearrangements...
February 24, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28235652/ultrasonographic-findings-of-thyroglossal-duct-papillary-carcinoma-a-case-report
#5
Chonticha Srivanitchapoom, Pichit Sittitrai, Kedsaraporn Yata, Piyadara Khongpiboonkit
INTRODUCTION: Reports on thyroglossal duct cyst carcinoma (TGDCCa) are rare, occurring in approximately 1% of thyroglossal duct cyst (TGDC) cases. The origin and treatment of carcinoma arising in TGDC are controversy. PRESENTATION OF CASE: A 38-year-old woman presented with a midline neck mass at the thyrohyoid level for 3 years. Ultrasound revealed a 2.4cm cystic mass with a solid mural component and microcalcification. A small right thyroid nodule was also detected...
February 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28231576/molecular-markers-involved-in-tumorigenesis-of-thyroid-carcinoma-focus-on-aggressive-histotypes
#6
Gustavo C Penna, Fernanda Vaisman, Mario Vaisman, Manuel Sobrinho-Simões, Paula Soares
Thyroid cancer derived from follicular cells (TCDFC) comprises well-differentiated (papillary and follicular) carcinoma, poorly differentiated carcinoma, and anaplastic carcinoma. Papillary thyroid carcinoma is the most common endocrine cancer, and its incidence is steadily increasing. Lethality and aggressiveness of TCDFC is inversely correlated with differentiation degree. In this review, an emphasis has been put on molecular markers involved in tumorigenesis of thyroid carcinoma with a focus on aggressive histotypes and the role of such biomarkers in predicting thyroid cancer outcome...
February 24, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28228903/i-131-uptake-in-fat-necrosis-of-the-breast
#7
Malak Itani, David H Lewis
I-131 uptake in the breast has been described with a variety of normal and pathologic conditions. We present the case of a 38-year-old female who received 317 millicuries of radioactive I-131 treatment for papillary thyroid carcinoma. Post-treatment scan demonstrated I-131 uptake in an area of fat necrosis in the breast.
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28226001/recombinant-human-tsh-versus-thyroid-hormone-withdrawal-in-adjuvant-therapy-with-radioactive-iodine-of-patients-with-papillary-thyroid-carcinoma-and-clinically-apparent-lymph-node-metastases-not-limited-to-the-central-compartment-cn1b
#8
Pedro Weslley Rosario, Gabriela Franco Mourão, Maria Regina Calsolari
Objective: To compare the short- and long-term outcomes of adjuvant therapy with radioactive iodine (RAI) preceded by the administration of recombinant human TSH (rhTSH) versus thyroid hormone withdrawal (THW) in patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central neck compartment (cN1b). Subjects and methods: The sample consisted of 178 cN1b patients at intermediate risk who underwent total thyroidectomy with apparently complete tumor resection [including postoperative ultrasonography (US) without anomalies] and who received adjuvant therapy with RAI (30-100 mCi) preceded by the administration of rhTSH (n = 91) or THW (n = 87)...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225995/clinical-impact-of-thyroglobulin-tg-and-tg-autoantibody-tgab-measurements-in-needle-washouts-of-neck-lymph-node-biopsies-in-the-management-of-patients-with-papillary-thyroid-carcinoma
#9
M Cecilia Martins-Costa, Rui M B Maciel, Teresa S Kasamatsu, Claudia C D Nakabashi, Cleber P Camacho, Felipe Crispim, Elza S Ikejiri, M Conceição O Mamone, Danielle M Andreoni, Rosa Paula M Biscolla
Objectives: The presence of thyroglobulin (Tg) in needle washouts of fine needle aspiration biopsy (Tg-FNAB) in neck lymph nodes (LNs) suspected of metastasis has become a cornerstone in the follow-up of patients with papillary thyroid carcinoma (PTC). However, there are limited data regarding the measurement of anti-Tg antibodies in these washouts (TgAb-FNAB), and it is not clear whether these antibodies interfere with the assessment of Tg-FNAB or whether there are other factors that would more consistently justify the finding of low Tg-FNAB in metastatic LNs...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225863/radiation-exposure-and-thyroid-cancer-a-review
#10
Maria Laura Iglesias, Angelica Schmidt, Abir Al Ghuzlan, Ludovic Lacroix, Florent de Vathaire, Sylvie Chevillard, Martin Schlumberger
The association between radiation exposure and the occurrence of thyroid cancer has been well documented, and the two main risk factors for the development of a thyroid cancer are the radiation dose delivered to the thyroid gland and the age at exposure. The risk increases after exposure to a mean dose of more than 0.05-0.1 Gy (50-100mGy). The risk is more important during childhood and decreases with increased age at exposure, being low in adults. After exposure, the minimum latency period before the appearance of thyroid cancers is 5 to 10 years...
February 16, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28224716/fine-needle-aspiration-cytology-of-the-papillary-thyroid-carcinoma-with-a-solid-component-a-cytological-and-clinical-correlation
#11
Ryuji Ohashi, Yukihiro Murase, Miyuki Matsubara, Yasuhiko Watarai, Takehito Igarashi, Iwao Sugitani, Zenya Naito
BACKGROUND: Solid variant of papillary thyroid carcinoma is a rare subtype of papillary thyroid carcinoma (PTC) containing a solid component (SC), and thus its cytological and clinicopathological features remain elusive. We examined fine needle aspiration (FNA) cytological features of PTC with variable degrees of SC (20-80% of the tumor)(PTCSC) in comparison to well-differentiated PTC (WPTC). METHODS: Twenty-six cases of PTCSC were histologically stratified into major-SC (SC >50% of the tumor) and minor-SC (<49%) groups...
February 22, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28224278/the-need-of-prophylactic-central-lymph-node-dissection-is-controversial-in-terms-of-postoperative-thyroglobulin-follow-up-of-patients-with-cn0-papillary-thyroid-cancer
#12
Mehmet Hakan Korkmaz, Bülent Öcal, Güleser Saylam, Erman Çakal, Ömer Bayır, Esra Tutal, Emel Çadallı Tatar
PURPOSE: The objective of this study was to investigate whether prophylactic central lymph node dissection (pCLND) facilitates postoperative thyroglobulin (Tg) follow-up in the patients with papillary thyroid carcinoma (PTC). We also questioned whether radioactive iodine (RAI) remnant ablation provides any further advantage in this regard. METHODS: The records of patients with low-intermediate risk PTC who underwent either only total thyroidectomy (TT) or TT in conjunction with pCLND were reviewed...
February 21, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28223766/cutaneous-implantation-metastasis-of-papillary-thyroid-carcinoma-following-fine-needle-aspiration-biopsy
#13
Chan Ho Na, Dong Jin Kim, Min Sung Kim, Bong Seok Shin
No abstract text is available yet for this article.
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28223546/skip-lateral-lymph-node-metastasis-leaping-over-the-central-neck-compartment-in-papillary-thyroid-carcinoma
#14
Jianyong Lei, Jinjing Zhong, Ke Jiang, Zhihui Li, Rixiang Gong, Jingqiang Zhu
OBJECTIVE: This study was performed to investigate the frequency and pattern as well as the predictive factors of skip metastasis (lateral cervical lymph node metastasis without central lymph node metastasis) in papillary thyroid carcinoma (PTC). METHODS: 450 PTC patients who received total thyroidectomy with central neck dissection(CND) combined with modified radical lateral neck dissection(LND) were divided into two groups: with or without skip metastases. The clinicopathological characteristics were statistically compared and analyzed, and univariate and multivariate analyses were performed to detect the risk factors of skip metastasis...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28223310/overexpression-of-vitamin-d-receptor-mrna-correlates-with-poor-prognosis-in-ptc
#15
June Young Choi, Jin Wook Yi, Joon-Hyop Lee, Ra-Yeong Song, Hyeong Won Yu, Hyungju Kwon, Young Jun Chai, Su-Jin Kim, Kyu Eun Lee
The purpose of this study was to assess the relationship between vitamin D receptor (VDR) mRNA expression and prognosis in papillary thyroid cancer. RNA sequencing and somatic mutation data from TCGA (the Cancer Genome Atlas) were analyzed. VDR mRNA expression was compared to clinicopathologic variables by linear regression. Tree-based classification was applied to find VDR cutoff and patients were split into low and high VDR group. Logistic regression, Kaplan-Meier analysis, differentially expressed gene (DEG) test, and pathway analysis were performed to assess differences between groups...
February 21, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28222967/clinical-implications-of-microscopic-extrathyroidal-extension-in-patients-with-papillary-thyroid-carcinoma
#16
Ji Su Park, Jae Won Chang, Lihua Liu, Seung-Nam Jung, Bon Seok Koo
BACKGROUND: Extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). However, the impact of the degree of ETE, especially microscopic ETE, has not been well established. The purpose of present study was to compare differences in clinicopathological characteristics and clinical outcomes according to the presence or extent of ETE. METHODS: Data from 381 patients who underwent total thyroidectomy with/without lymph node (LN) dissection for PTC between 2004 and 2010 were analyzed...
February 17, 2017: Oral Oncology
https://www.readbyqxmd.com/read/28222584/ultrasonographic-imaging-of-papillary-thyroid-carcinoma-variants
#17
Jung Hee Shin
Ultrasonography (US) is routinely used to evaluate thyroid nodules. The US features of papillary Epub ahead of print thyroid carcinoma (PTC), the most common thyroid malignancy, include hypoechogenicity, spiculated/microlobulated margins, microcalcifications, and a nonparallel orientation. However, many PTC variants have been identified, some of which differ from the classic type of PTC in terms of biological behavior and clinical outcomes. This review describes the US features and clinical implications of the variants of PTC...
January 12, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28222412/low-risk-papillary-thyroid-carcinoma-patients-who-underwent-near-total-thyroidectomy-without-prophylactic-central-compartment-lymph-node-dissection-and-were-ablated-with-low-dose-50mci-rai-had-excellent-10-year-prognosis
#18
Marina Michalaki, Panagiotis Bountouris, Nikolaos D Roupas, Anastasia Theodoropoulou, Niki Agalianou, Theodoros Alexandrides, Kostas Markou
BACKGROUND: The current trend in the management of low risk differentiated thyroid carcinoma is to follow less aggressive strategies. OBJECTIVE: To assess the long-term morbidity and mortality outcomes of low-risk papillary thyroid carcinoma (PTC) patients undergoing minimal intervention. DESIGN: We retrospectively analyzed 137 patients with low-risk PTC (stage I: n=77; stage II: n=60). Of these patients, 107 (Group 1) had macro-PTC and underwent near-total thyroidectomy and received postoperatively 50mCi RAI...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28221211/a-rare-case-of-ck20-ck7-double-negative-merkel-cell-carcinoma
#19
Mary D Le, Luke H OʼSteen, David S Cassarino
The authors present a case of Merkel cell carcinoma (MCC) with unique immunohistochemical staining characteristics. A 57-year-old woman presented with a firm 0.3 cm tan papule on her left nasal-labial fold that was reportedly increasing in size and bleeding. She had a history of multiple head and neck actinic keratoses, papillary thyroid carcinoma, and a family history of an uncle with melanoma. The clinical differential diagnosis was "non-melanoma skin cancer." Histological examination showed a markedly atypical-appearing basaloid neoplasm, present mostly in the dermis, with focal pagetoid spread into the epidermis...
March 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28219937/a-meta-analysis-of-prognostic-roles-of-molecular-markers-in-papillary-thyroid-carcinoma
#20
Huy Gia Vuong, Uyen N P Duong, Ahmed M A Altibi, Hanh T T Ngo, Thong Quang Pham, Hung Minh Tran, Greta Gandolfi, Lewis Hassell
The prognostic role of molecular markers in papillary thyroid carcinoma (PTC) is a matter of ongoing debate. The aim of our study is to investigate the impact of RAS, BRAF, TERT promoter mutations and RET/PTC rearrangements on prognosis of PTC patients. We performed a search in four electronic databases: PubMed, Scopus, Web of Science and Virtual Health Library (VHL). Data of hazard ratio (HR) and its 95% confidence interval (CI) for Disease-specific survival (DSS) and Disease-free survival (DFS) were directly obtained from original papers or indirectly estimated from Kaplan Meier curve (KMC)...
February 20, 2017: Endocrine Connections
keyword
keyword
14577
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"