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https://www.readbyqxmd.com/read/29232592/the-impact-of-oral-arsenic-and-all-trans-retinoic-acid-on-coagulopathy-in-acute-promyelocytic-leukemia
#1
Hong-Hu Zhu, Zhi-Ping Guo, Jin-Song Jia, Qian Jiang, Hao Jiang, Xiao-Jun Huang
The aim of our study was to evaluate the impact of oral arsenic (the realgar-indigo naturalis formula, RIF) and all-trans retinoic acid (ATRA) on coagulopathy in acute promyelocytic leukemia (APL) compared with intravenous arsenic trioxide (ATO) and ATRA during induction. Mitoxantrone was added to all the patients at a dose of 1.4mg/m2 per day for 5-7 days. D-dimer levels, prothrombin time (PT), fibrinogen (Fbg) levels and the platelet count were comparably analyzed among 83 newly diagnosed APL patients treated with RIF (n=45) or with ATO (n=38)...
November 15, 2017: Leukemia Research
https://www.readbyqxmd.com/read/29232381/effects-of-experimental-nitrogen-fertilization-on-planktonic-metabolism-and-co2-flux-in-a-hypereutrophic-hardwater-lake
#2
Matthew J Bogard, Kerri Finlay, Marley J Waiser, Vijay P Tumber, Derek B Donald, Emma Wiik, Gavin L Simpson, Paul A Del Giorgio, Peter R Leavitt
Hardwater lakes are common in human-dominated regions of the world and often experience pollution due to agricultural and urban effluent inputs of inorganic and organic nitrogen (N). Although these lakes are landscape hotspots for CO2 exchange and food web carbon (C) cycling, the effect of N enrichment on hardwater lake food web functioning and C cycling patterns remains unclear. Specifically, it is unknown if different eutrophication scenarios (e.g., modest non point vs. extreme point sources) yield consistent effects on auto- and heterotrophic C cycling, or how biotic responses interact with the inorganic C system to shape responses of air-water CO2 exchange...
2017: PloS One
https://www.readbyqxmd.com/read/29231722/selenium-iv-sorption-onto-%C3%AE-al2o3-a-consistent-description-of-the-surface-speciation-by-spectroscopy-and-thermodynamic-modeling
#3
Natalia Mayordomo, Harald Foerstendorf, Johannes Lutzenkirchen, Karsten Heim, Stephan Weiss, Ursula Alonso, Tiziana Missana, Katja Schmeide, Norbert Jordan
The sorption processes of Se(IV) onto γ-Al2O3 were studied by in situ Infrared spectroscopy, batch sorption studies, zeta potential measurements and Surface Complexation Modeling (SCM) in the pH range from 5 to 10. In situ Attenuated Total Reflection Fourier-transform Infrared (ATR FT-IR) spectroscopy revealed the predominant formation of a single inner-sphere surface species at the alumina surface, supporting previously reported EXAFS results, irrespective of the presence or absence of atmospherically derived carbonate...
December 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29229402/full-field-strain-distribution-in-multi-vertebra-spine-segments-an-in-vitro-application-of-digital-image-correlation
#4
Marco Palanca, Miguel Marco, Maria Luisa Ruspi, Luca Cristofolini
The biomechanics of the spine is experimentally assessed in terms of range of motion and overall stiffness. Quantification of the surface strain distribution is currently limited either to the vertebrae or the discs, whereas a full-field approach to measure the strain distribution in a multi-vertebra segment is currently missing. The aim of this work was to explore the feasibility of using Digital Image Correlation (DIC) to measure the strain distribution simultaneously on the vertebral bodies and the intervertebral discs of spine segments in different loading configurations...
December 8, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29221057/statistical-model-for-speckle-pattern-optimization
#5
Yong Su, Qingchuan Zhang, Zeren Gao
Image registration is the key technique of optical metrologies such as digital image correlation (DIC), particle image velocimetry (PIV), and speckle metrology. Its performance depends critically on the quality of image pattern, and thus pattern optimization attracts extensive attention. In this article, a statistical model is built to optimize speckle patterns that are composed of randomly positioned speckles. It is found that the process of speckle pattern generation is essentially a filtered Poisson process...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29220594/modification-of-immunological-features-in-human-platelets-during-sepsis
#6
Valle-Jiménez Xareni Raque, Sánchez-García Juan Carlos, Revilla-Rodríguez Eduardo, Baltierrez-Hoyos Rafael, Romero-Tlalolini María de Los Ángeles, Ramírez-Cosmes Adriana, Torres-Aguilar Honorio, Bustos-Arriaga José, Aguilar-Ruiz Sergio Roberto
Sepsis is an organic dysfunction that puts at risk the life of patients suffering this disorder due to an exacerbated immunological response to the infection mediated by the host. Platelets have been largely researched on sepsis owing to its role in Disseminated Intracellular Coagulation (DIC) and because thrombocytopenia is an important clinical feature of these patients. Nevertheless, a great number of evidence shows that platelets have also an important role in immunological response since they have pattern recognition receptors, chemokine receptors and granules with stored soluble mediators...
December 8, 2017: Immunological Investigations
https://www.readbyqxmd.com/read/29216953/-significance-of-heparin-in-the-treatment-of-patients-with-sepsis
#7
Qinlong Sun, Erzhen Chen
The latest definition of sepsis (Sepsis-3) is the life-threatening organ dysfunction due to overreaction of immune system caused by infection. The situation can develop into multiple organ dysfunction syndromes (MODS). In the pathological process of pathogen invasion, a large number of inflammatory factors directly damage organ function, while dysfunction of coagulation system is also involved in this process. With the overreaction of inflammation, disseminated intravascular coagulation (DIC) occurred, which further exacerbated organ damage...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29215847/-pathogenic-peculiarities-of-disseminated-intravascular-coagulation-of-various-ethiology
#8
E V Guzovskaya, S N Serebrennikova
DIC is a severe complication, often resulting in multi-organ failure and fatal outcome. As any syndrome, it is polyethiologic, while a big number of its causes logically leads to various mechanisms of its forming. Main manifestations of the disseminated intravascular blood coagulation syndrome are clottage and haemorrhage. A result of a massive clottage in microcirculatory bed of internal organs is development of dystrophic changes in them and organ failure. Haemorrhage in its turn, results in decreased volume of circulating blood, arterial hypotension and hemic hypoxia, in most severe cases leading to the fatal outcome...
April 2017: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
https://www.readbyqxmd.com/read/29215808/prognostic-performance-evaluation-of-the-international-society-on-thrombosis-and-hemostasis-and-the-korean-society-on-thrombosis-and-hemostasis-scores-in-the-early-phase-of-trauma
#9
Hong Sug Kim, Dong Hun Lee, Byung Kook Lee, Yong Soo Cho
BACKGROUND: Disseminated intravascular coagulation (DIC) contributes to poor outcome in the early phase of trauma. We aimed to analyze and compare the prognostic performances of the International Society on Thrombosis and Hemostasis (ISTH) and the Korean Society on Thrombosis and Hemostasis (KSTH) scores in the early phase of trauma. METHODS: Receiver operating characteristics analysis was used to examine the prognostic performance of both scores, and multivariate analysis was used to estimate the prognostic impact of the ISTH and KSTH scores in the early phase of trauma...
January 15, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29212728/coral-calcification-mechanisms-facilitate-adaptive-responses-to-ocean-acidification
#10
Verena Schoepf, Christopher P Jury, Robert J Toonen, Malcolm T McCulloch
Ocean acidification (OA) is a pressing threat to reef-building corals, but it remains poorly understood how coral calcification is inhibited by OA and whether corals could acclimatize and/or adapt to OA. Using a novel geochemical approach, we reconstructed the carbonate chemistry of the calcifying fluid in two coral species using both a pH and dissolved inorganic carbon (DIC) proxy (δ11B and B/Ca, respectively). To address the potential for adaptive responses, both species were collected from two sites spanning a natural gradient in seawater pH and temperature, and then subjected to three pHT levels (8...
December 6, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29208852/extremely-high-serum-ferritin-an-instrumental-marker-of-masquerading-adult-onset-still-s-disease-with-hemophagocytic-syndrome
#11
Shun Yamashita, Naoko E Furukawa, Tomoyo Matsunaga, Yuka Hirakawa, Masaki Tago, Shu-Ichi Yamashita
BACKGROUND Adult-onset Still's disease (AOSD) is a rare multi-systemic inflammatory disorder of unknown etiology characterized by spiking fever, characteristic rash, and arthritis. It often associates with high serum ferritin levels. CASE REPORT An 88-year-old woman had fever of over 39°C without response to extended-spectrum antibiotics for 6 days. She had non-specific erythema with infiltration on her trunk. She had leukocytosis with neutrophilia of 80%, mild hepatic dysfunction, normal level of rheumatoid factor and antinuclear antibody, thrombocytopenia, elevated d-dimer and soluble interleukin2 receptor, extremely high serum ferritin (78 662 ng/mL), and splenomegaly...
December 6, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29207788/hyperparathyroidism-during-pregnancy-a-diagnostic-and-therapeutic-challenge
#12
Richa Sharma, Bhanupriya, Vishnu Bhartiya, Kiran Guleria, Amita Suneja
Primary Hyperparathyroidism (PHP) is a rare event in pregnancy; Maternal complications in PHP patients can be as high as 67%. It can be overlooked easily because of many similar complaints shared by hyperparathyroidism and pregnancy such as nausea and vomiting, gastritis, bone aches, easy fatigability. Hypercalcemic crisis can develop resulting in coma and death. Neonatal effects are tetany and death in about 80% of cases. We report a case, of an antenatal woman at 30 weeks gestation with complains of painful swelling in left lower jaw and below right knee, pain over right hip joint and frequent episodes of gastritis...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205227/digital-image-correlation-techniques-for-strain-measurement-in-a-variety-of-biomechanical-test-models
#13
Sarah Hensley, Mackenzie Christensen, Scott Small, Derek Archer, Emily Lakes, Renee Rogge
PURPOSE: Previous biomechanical studies have estimated the strains of bone and bone substitutes using strain gages. However, applying strain gages to biological samples can be difficult, and data collection is limited to a small area under the strain gage. The purpose of this study was to compare digital image correlation (DIC) strain measurements to those obtained from strain gages in order to assess the applicability of DIC technology to common biomechanical testing scenarios. METHODS: Compression and bending tests were conducted on aluminum alloy, polyurethane foam, and laminated polyurethane foam specimens...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29202320/screening-itself-for-disseminated-intravascular-coagulation-may-reduce-mortality-in-sepsis-a-nationwide-multicenter-registry-in-japan
#14
Yutaka Umemura, Kazuma Yamakawa, Mineji Hayakawa, Toshimitsu Hamasaki, Satoshi Fujimi
OBJECTIVES: Screening of patients with sepsis for disseminated intravascular coagulation (DIC) has been recommended in several guidelines. However, DIC screening is still not widely accepted as an essential component of sepsis management, partly because of a lack of evidence that DIC screening has an effect on mortality. We investigated whether DIC screening was associated with a survival benefit in patients with sepsis. DESIGN: Post hoc analysis of a nationwide multicenter retrospective cohort study...
November 26, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29199627/selectively-electron-transparent-microstamping-toward-concurrent-digital-image-correlation-and-high-angular-resolution-electron-backscatter-diffraction-ebsd-analysis
#15
Timothy J Ruggles, Geoffrey F Bomarito, Andrew H Cannon, Jacob D Hochhalter
Digital image correlation (DIC) in a scanning electron microscope and high-angular resolution electron backscatter diffraction (HREBSD) provide valuable and complementary data concerning local deformation at the microscale. However, standard surface preparation techniques are mutually exclusive, which makes combining these techniques in situ impossible. This paper introduces a new method of applying surface patterning for DIC, namely a urethane microstamp, that provides a pattern with enough contrast for DIC at low accelerating voltages, but is virtually transparent at the higher voltages necessary for HREBSD and conventional EBSD analysis...
December 4, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/29197958/immunohaemostasis-a-new-view-on-haemostasis-during-sepsis
#16
REVIEW
Xavier Delabranche, Julie Helms, Ferhat Meziani
Host infection by a micro-organism triggers systemic inflammation, innate immunity and complement pathways, but also haemostasis activation. The role of thrombin and fibrin generation in host defence is now recognised, and thrombin has become a partner for survival, while it was seen only as one of the "principal suspects" of multiple organ failure and death during septic shock. This review is first focused on pathophysiology. The role of contact activation system, polyphosphates and neutrophil extracellular traps has emerged, offering new potential therapeutic targets...
December 2, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/29195202/exportation-of-dissolved-inorganic-and-organic-and-particulate-carbon-from-mangroves-and-its-implication-to-the-carbon-budget-in-the-indian-sundarbans
#17
R Ray, A Baum, T Rixen, G Gleixner, T K Jana
Mangroves are known for exchanging organic and inorganic carbon with estuaries and oceans but studies that have estimated their contribution to the global budget are limited to a few mangrove ecosystems which exclude world's largest the Sundarbans. Here, we worked in the Indian Sundarbans and in the Hooghly river/estuary in May (pre-monsoon) and December (post-monsoon), 2014. Aims were, i) to quantify the riverine export of particulate organic carbon (POC) and dissolved organic and inorganic carbon (DOC, DIC)) of the Hooghly into the Bay of Bengal (BoB), ii) to estimate the C export (DOC, DIC, POC) from the Sundarbans into the BoB by using a simple mixing model, as well as iii) to revise the existing C budget constructed for the mangroves...
November 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29194415/efficient-background-segmentation-and-seed-point-generation-for-a-single-shot-stereo-system
#18
Xiao Yang, Xiaobo Chen, Juntong Xi
Single-shot stereo 3D shape measurement is becoming more popular due to its advantages of noise robustness and short acquisition period. One of the key problems is stereo matching, which is related to the efficiency of background segmentation and seed point generation, etc. In this paper, a more efficient and automated matching algorithm based on digital image correlation (DIC) is proposed. The standard deviation of image gradients and an adaptive threshold are employed to segment the background. Scale-invariant feature transform (SIFT)-based feature matching and two-dimensional triangulation are combined to estimate accurate initial parameters for seed point generation...
December 1, 2017: Sensors
https://www.readbyqxmd.com/read/29192546/drip-infusion-cholangiography-with-ct-in-cats
#19
Toshiyuki Tanaka, Hideo Akiyoshi, Keiichiro Mie, Hitoshi Shimazaki, Fumihito Ohashi
Objectives Ultrasonography can detect extrahepatic biliary obstructions. However, visualisation of part of the bile duct using ultrasonography can be technically difficult if there is overlying bowel gas. This study investigated the safety and value of drip infusion cholangiography with computed tomography (DIC-CT) in the visualisation of the bile duct in healthy cats and extrahepatic biliary obstruction in cats with cholelithiasis. Methods DIC-CT was performed in three healthy cats and two cats with cholelithiasis...
November 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29188646/-application-of-temporomandibular-joint-dics-reduction-in-the-operation-of-condylar-sagittal-fracture
#20
Zeng Wenli, Zhou Wuchao, Zhang Jingkun, Shao Yisen, Xi Weihong
OBJECTIVE: To explore the selection of temporomandibular joint (TMJ) disc reduction and fixation methods in condylar sagittal fracture surgery. METHODS: A total of 36 patients with condylar fractures were chosen. The follow-up period was more 6 months. All 36 cases of condylar sagittal fracture were fixed with long screw. In the operation, the displaced joint disc was repositioned and fixed. The fixed method included direct suture (22 cases) and anchorage (14 cases)...
October 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
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