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Tan Bao, Garrett W Melenka, Megan K Ljubotina, Jason P Carey, James F Cahill
Rapidly determining root growth patterns is biologically important and technically challenging. Current methods focus on direct observation of roots and require destructive excavations or time-consuming root tracing. We developed a novel methodology based on analyzing soil particle displacement, rather than direct observation of roots. This inferred root growth method uses digital image correlation (DIC) analysis, an established and high-throughput method used in many engineering and science disciplines. By applying DIC analyses to repeated images of plants grown in clear window boxes, we produced visually intuitive and quantifiable strain maps, indicating the magnitude and direction of soil movement...
February 17, 2018: New Phytologist
Thibault Duburcq, Arthur Durand, Antoine Tournoys, Viviane Gnemmi, Valery Gmyr, François Pattou, Mercedes Jourdain, Fabienne Tamion, Emmanuel Besnier, Sebastien Préau, Erika Parmentier-Decrucq, Daniel Mathieu, Julien Poissy, Raphaël Favory
BACKGROUND: Sodium lactate seemed to improve fluid balance and avoid fluid overload. The objective of this study was to determine if these beneficial effects can be at least partly explained by an improvement in disseminated intravascular coagulation (DIC)-associated renal microvascular thrombosis. METHODS: Ancillary work of an interventional randomized open label controlled experimental study. Fifteen female "Large White" pigs (2 months old) were challenged with intravenous infusion of E...
February 14, 2018: Annals of Intensive Care
Yuan Zhang, Ying Wang, Ming-Qing Li, Jie Duan, Deng-Xuan Fan, Li-Ping Jin
Decidual immune cells (DICs), consisting of both innate and adaptive immune cells, have a pivotal role in maintaining immune tolerance for normal pregnancy. Our previous study demonstrated that interleukin (IL)-25 stimulates the proliferation of decidual stromal cells (DSCs) in an autocrine manner. However, the role of IL-25 in functional regulation of DICs is largely unknown. Flow cytometry was used to analyze the expression of IL-25 and its receptor (IL-17RB) in DICs, and the effect of IL-25 on the expression of Ki-67, IL-4, IL-10, interferon (IFN)-γ and transforming growth factor (TGF)-β in decidual γδT cells...
February 2018: Experimental and Therapeutic Medicine
T Nagy-Simon, M Potara, A-M Craciun, E Licarete, S Astilean
Due to the good transparency of the human tissue in the biological spectral window, near-infrared (NIR)-dye loaded nanosystems enable more effective light-activated therapy and better contrast imaging with major impact on nanomedicine. Herein, we prepare Pluronic coated gold nanoparticles incorporating the hydrophobic NIR dye, IR780 iodide (GNP-Plu-IR780) to provide water-solubility and stability and demonstrate the proficiency of combining photodynamic and photothermal therapeutic activity with surface-enhanced resonance Raman scattering (SERRS) imaging facility...
February 3, 2018: Journal of Colloid and Interface Science
Davide Vione, Angel Encinas, Debora Fabbri, Paola Calza
We predicted the possible direct and indirect phototransformation kinetics of carbamazepine (CBZ), ibuprofen (IBU) and diclofenac (DIC) in river water, based on data of water chemistry obtained for the Guadiana River near Badajoz (Southwestern Spain) during a year-round sampling campaign. The three compounds were chosen, (i) because they occurred at the outlet of the wastewater treatment plant (WWTP) in Badajoz, as well as in river water sampled 1 km downstream of the WWTP, and (ii) because their photochemical fate in surface waters is known well enough to be modelled...
February 3, 2018: Chemosphere
Belen Ferrer, David Mas
Digital Image Correlation (DIC) is a common tool for assessing the movement of objects in a scene. Among others, one of the most popular techniques consists of tracking a dotted texture imitating speckle patterns. In this work, we analyzed the individual dots that form this pattern in order to propose an optimum size, shape, and dynamic range that allows minimizing the tracking error. Tracking was accomplished by using normalized cross-correlation with peak interpolation in order to obtain subpixel accuracy...
February 9, 2018: Sensors
M Mezzelani, S Gorbi, D Fattorini, G d'Errico, G Consolandi, M Milan, L Bargelloni, F Regoli
Non-steroidal anti-inflammatory drugs (NSAIDs) represent a growing concern for marine ecosystems due to their ubiquitous occurrence and documented adverse effects on non-target organisms. Despite the remarkable efforts to elucidate bioaccumulation and ecotoxicological potential under short-term conditions, limited and fragmentary information is available for chronic exposures. In this study bioavailability, molecular and cellular effects of diclofenac (DIC), ibuprofen (IBU) and ketoprofen (KET) were investigated in mussels Mytilus galloprovincialis exposed to the realistic environmental concentration of 2...
February 2, 2018: Chemosphere
Sloan A Kulper, K Y Sze, Christian X Fang, Xiaodan Ren, Margaret Guo, Kerstin Schneider, Frankie Leung, William Lu, Alfonso Ngan
Many features of orthopaedic implants have been previously examined regarding their influence on migration in trabecular bone under axial loading, with screw thread design being one of the most prominent examples. There has been comparatively little investigation, however, of the influence that implant tip design has on migration under axial loads. We present a novel fracture mechanics model that explains how differences in tip design affect the force required for axial penetration of porous, compressible solids similar to trabecular bone...
February 3, 2018: Journal of the Mechanical Behavior of Biomedical Materials
C Ruiz de Arcaute, S Soloneski, M L Larramendy
Dicamba (DIC) and 2,4-dichlorophenoxyacetic acid (2,4-D) are two of the most applied auxinic herbicides worldwide, both individually and as part of a mixture. However, the toxicity and interactions achieved when applied as a mixture have not yet been characterised. The equitoxic and non-equitoxic acute toxicity exerted by binary mixtures of Banvel® (57.71% DIC) and DMA® (58.4% 2,4-D) on the Neotropical fish Cnesterodon decemmaculatus were evaluated. Results revealed mean values of 1.02 (range, 0.96-1.08) for the toxic unit (TU) that induced 50% mortality (TU50 96 h) to the fish exposed to binary equitoxic mixtures of the commercial formulations Banvel®-DMA®...
January 29, 2018: Environmental Pollution
Anna Gustafsson, Neashan Mathavan, Mikael J Turunen, Jonas Engqvist, Hanifeh Khayyeri, Stephen A Hall, Hanna Isaksson
The incidence of fragility fractures is expected to increase in the near future due to an aging population. Therefore, improved tools for fracture prediction are required to treat and prevent these injuries efficiently. For such tools to succeed, a better understanding of the deformation mechanisms in bone over different length scales is needed. In this study, an experimental setup including mechanical tensile testing in combination with digital image correlation (DIC) and small/wide angle x-ray scattering (SAXS/WAXS) was used to study deformation at multiple length scales in bovine cortical bone...
February 1, 2018: Acta Biomaterialia
Wen Cheng, Gurdiljot Singh Gill, John L Ensch, Jerry Kwong, Xudong Jia
Enhancement of safety for all transportation mode users plays an essential role in the implementation of multimodal transportation systems. Compared with crash frequency models dedicated to motorized mode users, the use of these models has been considerably scarce in the multimodal literature. To fill this research gap, the authors aimed to develop and evaluate three multivariate space-time models with different temporal trends and spatiotemporal interactions. The model estimates justified the use of mode-varying coefficients for explanatory variables as the impact of these factors varied across different crash modes...
February 2, 2018: Accident; Analysis and Prevention
Julie M Rosenthal, Mark W Johnson
Pregnancy leads to significant changes in the body, which potentially affect the retina. Pregnancy can induce disease, such as that seen in hypertensive retinopathy and choroidopathy. It can cause exudative retinal detachments in the HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), disseminated intravascular coagulation (DIC), and thrombotic thrombocytopenic purpura (TTP), and provoke arterial and venous retinal occlusive disease. Pregnancy may also exacerbate pre-existing retinal disease, such as idiopathic central serous chorioretinopathy (ICSC) and diabetic retinopathy...
January 2018: Journal of Ophthalmic & Vision Research
Danúbia Silva Dos Santos, Guilherme Visconde Brasil, Isalira Peroba Rezende Ramos, Fernanda Cristina Paccola Mesquita, Tais Hanae Kasai-Brunswick, Michelle Lopes Araújo Christie, Gustavo Monnerat Cahli, Raiana Andrade Quintanilha Barbosa, Sandro Torrentes da Cunha, Jonathas Xavier Pereira, Emiliano Medei, Antonio Carlos Campos de Carvalho, Adriana Bastos Carvalho, Regina Coeli Dos Santos Goldenberg
BACKGROUND: Doxorubicin (Dox) is a chemotherapy drug with limited application due to cardiotoxicity that may progress to heart failure. This study aims to evaluate the role of cardiomyocytes derived from mouse embryonic stem cells (CM-mESCs) in the treatment of Dox-induced cardiomyopathy (DIC) in mice. METHODS: The mouse embryonic stem cell (mESC) line E14TG2A was characterized by karyotype analysis, gene expression using RT-PCR and immunofluorescence. Cells were transduced with luciferase 2 and submitted to cardiac differentiation...
February 5, 2018: Stem Cell Research & Therapy
Ángel Jesús Molina-Viedma, Elías López-Alba, Luis Felipe-Sesé, Francisco A Díaz
The modal characterization of automotive lighting systems becomes difficult using sensors due to the light weight of the elements which compose the component as well as the intricate access to allocate them. In experimental modal analysis, high speed 3D digital image correlation (HS 3D-DIC) is attracting the attention since it provides full-field contactless measurements of 3D displacements as main advantage over other techniques. Different methodologies have been published that perform modal identification, i...
February 5, 2018: Materials
Zhenning Chen, Xinxing Shao, Xiangyang Xu, Xiaoyuan He
The technique of digital image correlation (DIC), which has been widely used for noncontact deformation measurements in both the scientific and engineering fields, is greatly affected by the quality of speckle patterns in terms of its performance. This study was concerned with the optimization of the digital speckle pattern (DSP) for DIC in consideration of both the accuracy and efficiency. The root-mean-square error of the inverse compositional Gauss-Newton algorithm and the average number of iterations were used as quality metrics...
February 1, 2018: Applied Optics
Yusuke Fujii, Noriyuki Hirahara, Shunsuke Kaji, Yoshiko Miyazaki, Takashi Kishi, Takahito Taniura, Ryoji Hyakudomi, Tetsu Yamamoto, Takeshi Nishi, Hikota Hayashi, Yasunari Kawabata, Yoshitsugu Tajima
A 60s-year-old Japanese male underwent curative resection for an advanced adenocarcinoma of the esophagogastric junction(Stage III C), followed by adjuvant chemotherapy.Twenty -one months later, he was admitted to our hospital with a complaint of marked decline in activities of daily living(ADL).The patient was diagnosed with pancytopenia, disseminated intravascular coagulation(DIC), multiple lymph node and bone metastases, and bone marrow carcinomatosis.After completing a sufficient informed consent process, he received chemotherapy along with blood transfusion, and then DIC, pancytopenia, and ADL of the patient improved...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Nobuhiko Ueda, Yoritaka Fujii, Seiko Miura, Jun Fujita, Yasuto Tomita, Toshio Ohnishi, Hideto Fujita, Shinichi Kinami, Kazuhiko Omote, Yasuharu Nakano, Takeo Kosaka, Yoshiharu Motoo
A 49-year-old man was referred to a neighboring hospital with a chief complaint of abdominal pain.He was diagnosed with locally advanced body-tail pancreatic cancer that had invaded the celiac artery and SMA.He came to our department after undergoing radiotherapy, 2.5 Gy×22 Fr, and chemotherapy with gemcitabine(GEM)and S-1.The same chemotherapy was continued for 15 months until DIC occurred.He was subsequently treated with GEM only and then S-1 only in sequence for 6 years.We decided to stop the chemotherapy because the original lesion had been stable for a long time...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Ángel Jesús Molina-Viedma, Elías López-Alba, Luis Felipe-Sesé, Francisco A Díaz, Javier Rodríguez-Ahlquist, Manuel Iglesias-Vallejo
In real aircraft structures the comfort and the occupational performance of crewmembers and passengers are affected by the presence of noise. In this sense, special attention is focused on mechanical and material design for isolation and vibration control. Experimental characterization and, in particular, experimental modal analysis, provides information for adequate cabin noise control. Traditional sensors employed in the aircraft industry for this purpose are invasive and provide a low spatial resolution...
February 2, 2018: Materials
Haoyu Wang, Ling Chang, Valeri Markine
Transition zones in railway tracks are locations with considerable changes in the rail-supporting structure. Typically, they are located near engineering structures, such as bridges, culverts and tunnels. In such locations, severe differential settlements often occur due to the different material properties and structure behavior. Without timely maintenance, the differential settlement may lead to the damage of track components and loss of passenger's comfort. To ensure the safety of railway operations and reduce the maintenance costs, it is necessary to consecutively monitor the structural health condition of the transition zones in an economical manner and detect the changes at an early stage...
January 31, 2018: Sensors
Qixin Wu, Guilin Han
In order to understand water chemistry after impoundment of the Three Gorges Reservoir (TGR), the authors assessed the hydrogeochemical parameters (water temperature, pH, conductivity, dissolved O2), major element composition, and the carbon stable isotopic value of dissolved inorganic carbon (δ13CDIC) in summer and winter at various depths in the water column at TGR in 2009. In reservoir water, the DO values are lower in winter than in summer, but the pH values and conductivity values are higher. Ca2+ and Na+ are the dominant cations and HCO3- and SO42- are the dominant anions...
January 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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