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https://www.readbyqxmd.com/read/29330781/a-review-of-the-methods-and-associated-mathematical-models-used-in-the-measurement-of-fat-free-mass
#1
REVIEW
Jaydeep Sinha, Stephen B Duffull, Hesham S Al-Sallami
Fat-free mass (FFM) represents the lean component of the body devoid of fat. It has been shown to be a useful predictor of drug dose requirements, particularly in obesity where the excess fat mass does not contribute to drug clearance. However, measuring FFM involves complex and/or expensive experimental methodologies that preclude their use in routine clinical practice. Thus, models to predict FFM from readily measurable variables, such as body weight and height, have been developed and are used in both population pharmacokinetic modelling and clinical practice...
January 12, 2018: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29330530/estimation-of-lean-body-mass-by-creatinine-kinetics-increases-the-prevalence-of-muscle-wasting-in-peritoneal-dialysis-patients-compared-to-bioimpedance
#2
Suree Yoowannakul, Andrew Davenport
Dialysis patients are at increased risk for muscle wasting, and time efficient screening tests are required for to allow for early detection. Creatinine kinetics have been advocated to estimate lean body mass (LBM) in peritoneal dialysis (PD) patients, and can be readily calculated in clinical practice from peritoneal dialysate effluent and urine collections. Bioimpedance is increasingly available, and we compared methods in 434 PD patients (55% men, 33.3% diabetics), mean age 55.2 ± 16.2 years. LBM was lower by creatinine kinetics (47...
January 12, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29330426/glucose-independent-segmental-phase-angles-from-multi-frequency-bioimpedance-analysis-to-discriminate-diabetes-mellitus
#3
Min-Ho Jun, Soochan Kim, Boncho Ku, JungHee Cho, Kahye Kim, Ho-Ryong Yoo, Jaeuk U Kim
We investigated segmental phase angles (PAs) in the four limbs using a multi-frequency bioimpedance analysis (MF-BIA) technique for noninvasively diagnosing diabetes mellitus. We conducted a meal tolerance test (MTT) for 45 diabetic and 45 control subjects stratified by age, sex and body mass index (BMI). HbA1c and the waist-to-hip-circumference ratio (WHR) were measured before meal intake, and we measured the glucose levels and MF-BIA PAs 5 times for 2 hours after meal intake. We employed a t-test to examine the statistical significance and the area under the curve (AUC) of the receiver operating characteristics (ROC) to test the classification accuracy using segmental PAs at 5, 50, and 250 kHz...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29319767/variables-associated-with-lung-congestion-as-assessed-by-chest-ultrasound-in-diabetics-undergoing-hemodialysis
#4
Paulo Roberto Santos, José Antonio de Lima Neto, Raimundo Aragão Aires Carneiro, Antônio Igor Taumaturgo Dias Soares, Wanessa Ribeiro de Oliveira, Juliana Oliveira Figueiredo, Narcélio Menezes Silva Filho, Thais Oliveira Silva
INTRODUCTION: Ultrasound is an emerging method for assessing lung congestion but is still seldom used. Lung congestion is an important risk of cardiac events and death in end-stage renal disease (ESRD) patients on hemodialysis (HD). OBJECTIVE: We investigated possible variables associated with lung congestion among diabetics with ESRD on HD, using chest ultrasound to detect extracellular lung water. METHODS: We studied 73 patients with diabetes as the primary cause of ESRD, undergoing regular HD...
October 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29318742/extracellular-water-excess-and-increased-self-reported-fatigue-in-chronic-hemodialysis-patients
#5
Kamonwan Tangvoraphonkchai, Andrew Davenport
Hemodialysis patients (HD) commonly report fatigue. Muscle wasting (sarcopenia) and extracellular water (ECW) excess have been reported to be associated with fatigue in other conditions. We wished to determine whether muscle loss and ECW excess were associated with fatigue in HD patients. Patients completed the Multidimensional Fatigue Inventory (MFI), Beck Depression Inventory-II (BDI-II), Patient Health Questionnaires (PHQ-9) and recorded their post-dialysis recovery time. Sessional dialysis data were recorded along with pre- and post-dialysis multi-frequency bioimpedance assessments (MFBIA)...
January 10, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29316025/impedance-spectroscopy-measurements-as-a-tool-for-distinguishing-different-luminal-content-during-bolus-transit-studies
#6
A Ruiz-Vargas, R Mohd Rosli, A Ivorra, J W Arkwright
BACKGROUND: Intraluminal electrical impedance is a well-known diagnostic tool used to study bolus movement in the human esophagus. However, it is use in the human colon it is hindered by the fact that the content cannot be controlled and may include liquid, gas, solid, or a mixture of these at any one time. This article investigates the use of complex impedance spectroscopy to study different luminal content (liquid and gas). METHODS: An excised section of guinea pig proximal colon was placed in an organ bath with Krebs solution at 37°C and a custom built bioimpedance catheter was placed in the lumen...
January 8, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29315019/time-and-intervention-effects-of-daily-almond-intake-on-the-changes-of-lipid-profile-and-body-composition-among-free-living-healthy-adults
#7
Yanan Liu, Hyo-Jeong Hwang, Hyun-Sook Kim, Hyunjin Park
Favorable health benefits of almond have been shown in several previous studies. However, repeated measures, randomized, controlled trials to investigate the changes due to almond intake based on the time effects have not yet been reported. The current study was conducted to evaluate the effects of daily almond intake on changes in body composition and lipid profiles for 20 weeks with four measurements among healthy adults. Participants in the almond group showed favorable changes on blood lipid profiles, including levels of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-high-density lipoprotein (non-HDL-C) after consuming 56 g of almond per day for 20 weeks compared with those at baseline...
January 9, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29314721/peritoneal-protein-losses-depend-on-more-than-just-peritoneal-dialysis-modality-and-peritoneal-membrane-transporter-status
#8
Suree Yoowannakul, Lauren S Harris, Andrew Davenport
Peritoneal protein clearance (PPCl) depends upon vascular supply and size selective permeability. Some previous reports suggested PPCl can distinguish fast peritoneal membrane transport due to local or systemic inflammation. However, as studies have been discordant, we wished to determine factors associated with an increased PPCl. Consecutive patients starting peritoneal dialysis (PD) who were peritonitis-free were studied. Data included a baseline peritoneal equilibration test (PET), measurement of dialysis adequacy, 24-h dialysate PPCl and body composition measured by multifrequency bioimpedance...
January 4, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29303992/relationships-between-breastfeeding-patterns-and-maternal-and-infant-body-composition-over-the-first-12-months-of-lactation
#9
Zoya Gridneva, Alethea Rea, Anna R Hepworth, Leigh C Ward, Ching T Lai, Peter E Hartmann, Donna T Geddes
Breastfeeding has been implicated in the establishment of infant appetite regulation, feeding patterns and body composition (BC). A holistic approach is required to elucidate relationships between infant and maternal BC and contributing factors, such as breastfeeding parameters. Associations between maternal and breastfed term infant BC (n = 20) and feeding parameters during first 12 months of lactation were investigated. BC was measured at 2, 5, 9 and/or 12 months postpartum with ultrasound skinfolds (US; infants only) and bioimpedance spectroscopy (infants and mothers)...
January 5, 2018: Nutrients
https://www.readbyqxmd.com/read/29303488/small-intestinal-ischemia-and-reperfusion-bioimpedance-measurements
#10
Runar James Strand-Amundsen, Christian Tronstad, Havard Kalvoy, Tom Erik Ruud, Jan Olav Hogetveit, Orjan Grottem Martinsen, Tor Inge Tønnessen
Trans-intestinal bioimpedance measurements have previously been used to investigate changes in electrical parameters during 6 hours of ischemia in the small intestine. Knowledge is lacking regarding the time course of trans-intestinal bioimpedance parameters during reperfusion. As reperfusion is an important part in the clinical treatment of intestinal ischemia, we need to know how it affects the bioimpedance measurements. Approach: We performed bioimpedance measurements, using a two-electrode setup on selected segments of the jejunum in 15 pigs...
January 5, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29301558/leucine-and-ace-inhibitors-as-therapies-for-sarcopenia-lace-trial-study-protocol-for-a-randomised-controlled-trial
#11
Margaret M Band, Deepa Sumukadas, Allan D Struthers, Alison Avenell, Peter T Donnan, Paul R Kemp, Karen T Smith, Cheryl L Hume, Adrian Hapca, Miles D Witham
BACKGROUND: Sarcopenia (the age-related loss of muscle mass and function) is a major contributor to loss of mobility, falls, loss of independence, morbidity and mortality in older people. Although resistance training is effective in preventing and reversing sarcopenia, many older people are sedentary and either cannot or do not want to exercise. This trial examines the efficacy of supplementation with the amino acid leucine and/or angiotensin converting enzyme inhibition to potentially improve muscle mass and function in people with sarcopenia...
January 4, 2018: Trials
https://www.readbyqxmd.com/read/29298736/multiple-frequency-bioimpedance-devices-for-fluid-management-in-people-with-chronic-kidney-disease-receiving-dialysis-a-systematic-review-and-economic-evaluation
#12
Graham Scotland, Moira Cruickshank, Elisabet Jacobsen, David Cooper, Cynthia Fraser, Michal Shimonovich, Angharad Marks, Miriam Brazzelli
BACKGROUND: Chronic kidney disease (CKD) is a long-term condition requiring treatment such as conservative management, kidney transplantation or dialysis. To optimise the volume of fluid removed during dialysis (to avoid underhydration or overhydration), people are assigned a 'target weight', which is commonly assessed using clinical methods, such as weight gain between dialysis sessions, pre- and post-dialysis blood pressure and patient-reported symptoms. However, these methods are not precise, and measurement devices based on bioimpedance technology are increasingly used in dialysis centres...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29284797/bedside-quantification-of-fat-free-mass-in-acute-spinal-cord-injury-using-bioelectrical-impedance-analysis-a-psychometric-study
#13
Maya G Panisset, Kate Desneves, Leigh C Ward, Jillian Rafferty, Helena Rodi, Geoff Roff, Doa El-Ansary, Mary P Galea
STUDY DESIGN: Psychometric. OBJECTIVES: Assess the validity of bioimpedance-based measures of fat-free mass (FFM) in acute SCI and of current definitions of obesity based on body mass index (BMI). SETTING: Australia. METHODS: All admissions within eight weeks of a new traumatic SCI were screened. 29% were eligible. 71% of those consented. Twenty participants (18 male) completed deuterium dilution (DD) and bioimpedance-based measurements of FFM...
December 28, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29282003/fluid-status-evaluation-by-inferior-vena-cava-diameter-and-bioimpedance-spectroscopy-in-pediatric-chronic-hemodialysis
#14
Xavier Torterüe, Laurène Dehoux, Marie-Alice Macher, Olivier Niel, Thérésa Kwon, Georges Deschênes, Julien Hogan
BACKGROUND: Evaluation of patient's dry weight remains challenging in chronic hemodialysis (HD) especially in children. Inferior Vena Cava (IVC) measurement was reported useful to assess fluid overload both in adults and children. METHODS: We performed a monocentric prospective study to evaluate the relation between predialytic IVC diameter measurements and hydration status evaluated by physicians and bioimpedance spectroscopy (BIS) and between IVC measurements and persistent hypertension...
December 28, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29280647/-relation-of-variant-rs180077-of-gen-cholesterol-ester-transfer-protein-variant-with-fat-mass-hdl-cholesterol-in-obese-subjects-with-diabetes-mellitus-type-2
#15
Daniel Antonio De Luis, Olatz Izaola, David Primo, Susana García Calvo, Emilia Gómez Hoyos, Juan José López Gómez, Ana Ortola, Cristina Serrano, Esther Delgado, Beatriz Torres Torres
BACKGROUND: There is few evidence of cholesterol ester transfer protein (CETP) in subjects with obesity and diabetes mellitus. OBJECTIVES: We examined the association of the polymorphism (rs1800777) of CETP gene on anthropometric parameters, lipid profile and adipokines in subjects with obesity and diabetes mellitus type 2. MATERIAL AND METHODS: A population of 229 obese subjects with diabetes mellitus type 2 was enrolled. An electrical bioimpedance, blood pressure, dietary intake, exercise and biochemical analyses were recorded...
November 14, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29279059/systemic-inflammation-mediates-the-detrimental-effects-of-obesity-on-asthma-control
#16
Xin Zhang, Jing Zheng, Li Zhang, Ying Liu, Gai Ping Chen, Hong Ping Zhang, Lei Wang, De Ying Kang, Lisa G Wood, Gang Wang
BACKGROUND: Obesity negatively impacts asthma control, but the inflammatory mechanisms are poorly understood. OBJECTIVE: To explore which systemic inflammatory mediators mediate the effects of obesity on asthma control. METHODS: The subjects with stable asthma (n = 108) underwent assessment of clinical characteristics, which included using The Asthma Control Questionnaire (ACQ)-6. Obesity was defined as a body mass index (BMI) of ≥30 kg/m2, overweight was defined as BMI between 25 to 29...
January 2, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29274919/use-of-lung-ultrasound-for-the-assessment-of-volume-status-in-ckd
#17
REVIEW
Adrian Covic, Dimitrie Siriopol, Luminita Voroneanu
Adequate assessment of fluid status is an imperative objective in the management of all types of patients in cardiology, intensive care, and especially nephrology. Fluid overload is one of the most common modifiable risk factors directly associated with hypertension, heart failure, left ventricular hypertrophy, and eventually, higher morbidity and mortality risk in these categories of patients. Different methods are commonly used to determine fluid status (eg, clinical assessment, natriuretic peptide concentrations, echocardiography, inferior vena cava measurements, or bioimpedance analysis)...
December 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29273924/changes-in-physical-activities-and-body-composition-after-roux-y-gastric-bypass-surgery
#18
Alex Harley Crisp, Rozangela Verlengia, Michele Novaes Ravelli, Irineu Rasera Junior, Maria Rita Marques de Oliveira
PURPOSE: Given the importance of physical activities for health outcomes, it is still unclear whether bariatric surgery per se and the standard care after surgery would result in an increase of physical activity level. This study aimed to determine physical activities preoperatively and at 6 and 12 months postoperatively among female patients who underwent bariatric surgery, and to investigate its relationship with body composition changes. MATERIAL AND METHODS: Thirty-four women who had Roux-Y gastric bypass (RYGB) surgery completed the study...
December 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29242410/adiposity-and-cortisol-response-to-stress-in-indian-adolescents
#19
G V Krishnaveni, A Jones, S R Veena, R Somashekara, S C Karat, C H D Fall
OBJECTIVE: Greater adiposity is a risk factor for altered hypothalamic-pituitary-adrenal axis reactivity to stress. We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN: Cohort study. SETTING: Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS: Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...
December 14, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29236911/assessment-of-the-quality-of-life-muscle-strength-and-dynamic-balance-of-elderly-kendo-players
#20
Dário Lucas Costa de Mendonça, Angelica Castilho Alonso, Júlia Maria D'Andrea Greve, Luiz Eugênio Garcez-Leme
OBJECTIVE: To compare Kendo players with active elderly adults in terms of quality of life, functional aspects (muscle strength, postural balance) and body composition. METHODS: This was a controlled cross-sectional study. Twenty elderly individuals were divided into two groups: the Kendo group, with an average age of 71.8 (5.4) years, and the Control group, with an average age of 73.1 (4.8) years. Quality of life was evaluated using a questionnaire (WHOQOL-bref and WHOQOL-old); body composition was evaluated with a bioimpedance scale (InBody230); hand-grip strength was assessed with a portable manual dynamometer (Jamar SH 5001); flexor and extensor muscle strength of the knees was evaluated with an isokinetic device (Biode® System 3 model Biodex Multi Joint System, BIODEX); and dynamic balance was assessed using a force platform (Balance Master System, Neurocom International, Inc...
November 2017: Clinics
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