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https://www.readbyqxmd.com/read/28228001/fabrication-of-progesterone-loaded-nanofibers-for-the-drug-delivery-applications-in-bovine
#1
Chitra Karuppannan, Mehnath Sivaraj, J Ganesh Kumar, Rangasamy Seerangan, S Balasubramanian, Dhinakar Raj Gopal
Progesterone is a potent drug for synchronization of the estrus and ovulation cycles in bovine. At present, the estrus cycle of bovine is controlled by the insertion of progesterone-embedded silicone bands. The disadvantage of nondegradable polymer inserts is to require for disposal of these bands after their use. The study currently focuses on preparation of biodegradable progesterone-incorporated nanofiber for estrus synchronization. Three different concentrations (1.2, 1.9, and 2.5 g) of progesterone-impregnated nanofibers were fabricated using electrospinning...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28227997/an-autoclavable-wireless-palpation-instrument-for-minimally-invasive-surgery
#2
Anish S Naidu, Abelardo Escoto, Omar Fahmy, Rajni V Patel, Michael D Naish, Anish S Naidu, Abelardo Escoto, Omar Fahmy, Rajni V Patel, Michael D Naish, Abelardo Escoto, Omar Fahmy, Michael D Naish, Anish S Naidu, Rajni V Patel
Minimally invasive surgery prevents surgeons from manually palpating organs to locate subsurface tumors and other structures. One solution is to use ultrasound; however, it is not always reliable. Various minimally invasive surgery instruments that provide tactile feedback have been proposed to augment ultrasound sensing for tumor localization; however, current designs have limitations such as cumbersome wiring, difficulty in manipulation, lack of sterilizability and high cost. This paper presents a novel, autoclavable, wireless, hand-held palpation instrument that uses a custom, low-cost, disposable tactile sensor to provide tactile and kinesthetic force feedback...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227992/modeling-and-design-of-antennas-for-implantable-telemetry-applications
#3
Arun Venkatasubramanian, Brandon Gifford, Arun Venkatasubramanian, Brandon Gifford, Brandon Gifford, Arun Venkatasubramanian
Incorporating an RF communications link in an implanted medical device can increase its range of applicability and improve quality of life for the patient. Developments in support electronics decrease design risk, but the implanted antenna remains a critical component of a communications link that operates at very low received power. Transmitted power is limited both by regulatory restrictions and, for most implanted devices, by power source capacity. Dielectric losses and wave trapping in the body result in transmission losses much greater than seen in free space communications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227957/bidirectional-peripheral-nerve-interface-and-applications
#4
Nitish V Thakor, Qihong Wang, Elliot Greenwald, Nitish V Thakor, Qihong Wang, Elliot Greenwald, Elliot Greenwald, Nitish V Thakor, Qihong Wang
Peripheral nerves, due to their small size and complex innervation to organs and complex physiology, pose particularly significant challenges towards interfacing electrodes and electronics to enable neuromodulation. Here, we present a review of the technology for building such interface, including recording and stimulating electrodes and low power electronics, as well as powering. Of particular advantage to building a miniature implanted device is a "bidirectional" system that both senses from the nerves or surrogate organs and stimulates the nerves to affect the organ function...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227955/cmos-based-opto-electronic-neural-interface-devices-for-optogenetics
#5
Takashi Tokuda, Satoki Noguchi, Satoru Iwasaki, Hiroaki Takehara, Toshihiko Noda, Kiyotaka Sasagawa, Jun Ohta, Takashi Tokuda, Satoki Noguchi, Satoru Iwasaki, Hiroaki Takehara, Toshihiko Noda, Kiyotaka Sasagawa, Jun Ohta, Toshihiko Noda, Kiyotaka Sasagawa, Satoru Iwasaki, Takashi Tokuda, Satoki Noguchi, Hiroaki Takehara, Jun Ohta
CMOS-based opto-electronic neural interface devices are presented. The devices are designed with target application of in vitro and in vivo optogenetics. Two types of the opto-electronic neural interface devices are presented. One is single-chip type device for on-chip optogenetics, and the other is multi-chip type device with flexibility and wide-area coverage for in vivo optogenetics on brain. Design, packaging and functional evaluations are presented.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227855/simultaneous-reconstruction-and-segmentation-with-the-mumford-shah-functional-for-electron-tomography
#6
Li Shen, Eric Todd Quinto, Shiqiang Wang, Ming Jiang, Li Shen, Eric Todd Quinto, Shiqiang Wang, Ming Jiang, Ming Jiang, Eric Todd Quinto, Shiqiang Wang, Li Shen
Electron micrography (EM) is an important method for determining the three-dimensional (3D) structure of macromolecular complexes and biological specimens. But there are several limitations such as poor signal-to-noise, limitation on range of tilt angles and sub-region subject to electron exposure, unintentional movements of the specimen, with EM systems that make the reconstruction procedure a severely ill-posed problem. A different choice of reconstruction method may lead to different results and create different additional artifacts in reconstructed images...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227814/embedded-cmos-basecalling-for-nanopore-dna-sequencing
#7
Chengjie Wang, Junli Zheng, Sebastian Magierowski, Ebrahim Ghafar-Zadeh, Chengjie Wang, Junli Zheng, Sebastian Magierowski, Ebrahim Ghafar-Zadeh, Junli Zheng, Chengjie Wang, Ebrahim Ghafar-Zadeh, Sebastian Magierowski
DNA sequencing based on nanopore sensors is now entering the marketplace. The ability to interface this technology to established CMOS microelectronics promises significant improvements in functionality and miniaturization. Among the key functions to benefit from this interface will be basecalling, the conversion of raw electronic molecular signatures to nucleotide sequence predictions. This paper presents the design and performance potential of custom CMOS base-callers embedded alongside nanopore sensors. A basecalliing architecture implemented in 32-nm technology is discussed with the ability to process the equivalent of 20 human genomes per day in real-time at a power density of 5 W/cm(2) assuming a 3-mer nanopore sensor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227779/revealing-oral-medication-patterns-from-reconstructed-long-term-medication-history-of-type-2-diabetes
#8
Purnomo Husnul Khotimah, Yuichi Sugiyama, Masatoshi Yoshikawa, Akihiro Hamasaki, Kazuya Okamoto, Tomohiro Kuroda, Purnomo Husnul Khotimah, Yuichi Sugiyama, Masatoshi Yoshikawa, Akihiro Hamasaki, Kazuya Okamoto, Tomohiro Kuroda, Kazuya Okamoto, Purnomo Husnul Khotimah, Yuichi Sugiyama, Akihiro Hamasaki, Masatoshi Yoshikawa, Tomohiro Kuroda
With the growing attention to evidence-based medical guideline development, longitudinal analysis of Electronic Medical Records (EMR) has become a good tool for providing insight into and new knowledge on the existing therapy. For chronic diseases, longitudinal analysis of medication history plays a key role in reaching this goal. However, raw medication data in EMR are not suitable for longitudinal analysis for several reasons. First, many prescriptions have a short duration. Second, the prescription duration may have a gap or overlap with other prescription durations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227724/location-aware-distributed-file-allocation-for-low-delay-access-to-electronic-medical-records
#9
Ziyang Chen, Mohammad Shikh-Bahaei, Ziyang Chen, Mohammad Shikh-Bahaei, Mohammad Shikh-Bahaei, Ziyang Chen
A new distributed file allocation method using femtocaching is designed to decrease the delay in accessing the Electronic Medical Records (EMR). The simulation results show that the proposed scheme can reduce the delay by 41.11% to 93.3%.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227680/a-mobile-platform-for-automated-screening-of-asthma-and-chronic-obstructive-pulmonary-disease
#10
Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher, Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher, Daniel B Chamberlain, Richard Ribon Fletcher, Rahul Kodgule
Chronic Obstructive Pulmonary Disease (COPD) and asthma each represent a large proportion of the global disease burden; COPD is the third leading cause of death worldwide and asthma is one of the most prevalent chronic diseases, afflicting over 300 million people. Much of this burden is concentrated in the developing world, where patients lack access to physicians trained in the diagnosis of pulmonary disease. As a result, these patients experience high rates of underdiagnosis and misdiagnosis. To address this need, we present a mobile platform capable of screening for Asthma and COPD...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227665/hardware-design-for-a-cable-free-fully-insertable-wireless-laparoscopic-robotic-camera
#11
Ning Li, Gregory J Mancini, Jindong Tan, Ning Li, Gregory J Mancini, Jindong Tan, Gregory J Mancini, Ning Li, Jindong Tan
The field of insertable laparoscopic robotic camera is gaining increasing attentions from researchers, surgeons, and also patients. Although many insertable laparoscope prototypes have been introduced, few of them get rid of the encumbrance tethering cable. In this paper, we proposed a hardware architecture for a magnetic actuated robotic surgical (MARS) camera, which facilitates a cable-free fully insertable laparoscopic surgical robotic camera with adequate in-vivo mobility. Modular design and preliminary test of on-board functional payloads have shown feasibility of a cable-free insertable wireless laparoscopic surgical camera based on off-the-shelf electronics and industrial wireless standards operating in ISM frequency bands at 2...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227589/uhf-wearable-battery-free-sensor-module-for-activity-and-falling-detection
#12
Nam Trung Dang, Thang Viet Tran, Wan-Young Chung, Nam Trung Dang, Thang Viet Tran, Wan-Young Chung, Thang Viet Tran, Wan-Young Chung, Nam Trung Dang
Falling is one of the most serious medical and social problems in aging population. Therefore taking care of the elderly by detecting activity and falling for preventing and mitigating the injuries caused by falls needs to be concerned. This study proposes a wearable, wireless, battery free ultra-high frequency (UHF) smart sensor tag module for falling and activity detection. The proposed tag is powered by UHF RF wave from reader and read by a standard UHF Electronic Product Code (EPC) Class-1 Generation-2 reader...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227506/a-pdms-based-optical-waveguide-for-transcutaneous-powering-of-microelectrode-arrays
#13
Ali Ersen, Mesut Sahin, Ali Ersen, Mesut Sahin, Ali Ersen, Mesut Sahin
Implantable microelectrode arrays (MEAs) usually have on-site electronics that need to be powered, both in neural recording and stimulation applications. Interconnecting wires between implanted electrodes and the outside world constitute a major source of complications. Our solution to this tethering problem is to design a light waveguide that can collect the optical power transcutaneously and transmit it to the microelectrode array where it is to be converted to an electric current. A polydimethylsiloxane (PDMS)-based waveguide was fabricated and its attenuation was measured in vitro and found to be 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227497/a-wireless-system-with-stimulation-and-recording-capabilities-for-interfacing-peripheral-nerves-in-rodents
#14
P Schonle, F Michoud, N Brun, A Guex, S P Lacour, Q Wang, Q Huang, P Schonle, F Michoud, N Brun, A Guex, S P Lacour, Q Wang, Q Huang, N Brun, A Guex, P Schonle, Q Huang, Q Wang, S P Lacour, F Michoud
Considerable progress has been made in the last decade in implantable bioelectronic neurosystems. Yet most neural implants are used in acute and tethered experimental conditions. Here, we present a preliminary prototype of a multichannel system for simultaneous peripheral nerve stimulation and neural recording. The system comprises miniaturized electronics with a total volume of less then 1.4cm(3) including a 3.7V battery which is expected to last for 94 days of standby operation or 18 hours of continuous recording and stimulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227479/a-low-cost-3-d-printed-stethoscope-connected-to-a-smartphone
#15
Carlos Aguilera-Astudillo, Marx Chavez-Campos, Alan Gonzalez-Suarez, Jose L Garcia-Cordero, Carlos Aguilera-Astudillo, Marx Chavez-Campos, Alan Gonzalez-Suarez, Jose L Garcia-Cordero, Jose L Garcia-Cordero, Alan Gonzalez-Suarez, Marx Chavez-Campos
We demonstrate the fabrication of a digital stethoscope using a 3D printer and commercial off-the-shelf electronics. A chestpiece consists of an electret microphone embedded into the drum of a 3D printed chestpiece. An electronic dongle amplifies the signal from the microphone and reduces any external noise. It also adjusts the signal to the voltages accepted by the smartphones headset jack. A graphical user interface programmed in Android displays the signals processed by the dongle. The application also saves the processed signal and sends it to a physician...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227441/novel-ti-nb-alloys-with-improved-wear-resistance-for-biomedical-implant-application
#16
Praveen Chapala, Swati Ghosh Acharyya, S M Shariff, Ganesh Naik, Praveen Chapala, Swati Ghosh Acharyya, S M Shariff, Ganesh Naik, Ganesh Naik, S M Shariff, Praveen Chapala, Swati Ghosh Acharyya
The present study involved fabrication of titanium niobium based alloys having elastic modulus close to that of human bone and subsequently determining the wear resistance of these alloys for biomedical application. In the present study three beta stabilized titanium niobium alloys having composition Ti-24Nb-4Zr-8Sn, Ti-35Nb-4Sn and Ti-29Nb-13Ta-7Zr were made by vacuum arc melting. The alloys were then aged at 1000 C for 6 hours in an argon atmosphere. Detailed microstructural characterization and phase identification was carried out using scanning electron microscopy and x-ray diffraction respectively...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227385/statistical-characterization-of-ensembles-of-symmetric-virus-particles-3-d-stochastic-signal-reconstruction-from-electron-microscope-images
#17
Nan Xu, Peter C Doerschuk, Nan Xu, Peter C Doerschuk, Nan Xu, Peter C Doerschuk
Stochastic models of nano-biomachines have been studied by 3-D reconstruction from cryo electron microscopy images in recent years. The image data is the projection of many heterogeneous instances of the object under study (e.g., a virus). Initial reconstruction algorithms require different instances of the object, while still heterogeneous, to have the same symmetry. This paper presents a maximum likelihood reconstruction approach which allows each object to lack symmetry while constraining the statistics of the ensemble of objects to have symmetry...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227238/design-and-development-of-a-sensorized-cylindrical-object-for-grasping-assessment
#18
F Cordella, F Taffoni, L Raiano, G Carpino, M Pantoni, L Zollo, E Schena, E Guglielmelli, D Formica, F Cordella, F Taffoni, L Raiano, G Carpino, M Pantoni, L Zollo, E Schena, E Guglielmelli, D Formica, M Pantoni, F Cordella, G Carpino, E Schena, L Zollo, D Formica, F Taffoni, L Raiano, E Guglielmelli
Aim of this work is to design and develop an instrumented cylindrical object equipped with force sensors, which is able to assess grasping performance of both human and robotic hands. The object is made of two concentric shells between which sixteen piezoresistive sensors have been located in order to measure the forces applied by the hand fingers during grasping. Furthermore, a magneto-inertial unit has been positioned inside the object for acquiring information about object orientation during manipulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227206/effects-of-phase-aberration-correction-methods-on-the-minimum-variance-beamformer
#19
Gustavo R Chau, Jeremy J Dahl, Roberto J Lavarello, Gustavo R Chau, Jeremy J Dahl, Roberto J Lavarello, Gustavo R Chau, Roberto J Lavarello
The minimum variance (MV) beamformer is a method that has the potential to enhance the resolution and contrast of ultrasound images. However, it suffers from sensitivity to speed of sound errors and aberration. Although there have been several studies on the application of phase aberration correction (PAC) methods to conventional delay-and-sum (DAS) beamforming, the benefits of PAC methods in mitigating the effects of phase aberration in MV beamformed images are not well understood. A study of this type would be helpful in designing a robust beamformer based on PAC knowledge present in the literature...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227188/conformai-electronics-for-longitudinal-bio-sensing-in-at-home-assistive-and-rehabilitative-devices
#20
John C Batchelor, Stephen G Yeates, Alexander J Casson, John C Batchelor, Stephen G Yeates, Alexander J Casson, Stephen G Yeates, John C Batchelor, Alexander J Casson
Wearable electronics are revolutionizing personalized and preventative healthcare by allowing the easy, unobtrusive, and long term monitoring of a range of body parameters. Conformal electronics which attach directly to the skin in a very robust and long term manner are envisioned as the next generation of highly portable miniaturized computing devices, beyond wearables. In this paper we overview the state-of-the-art in conformal electronics created using silver nanoparticle inkjet printed techniques for home assistive and rehabilitative devices...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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