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https://www.readbyqxmd.com/read/27921424/-mind-as-an-immunomodulator
#1
Cyril Höschl, Jiří Horáček
Review paper highlights the connection between psyche and the bodys immune defense mechanisms and summarizes new findings on the relations between nervous and immune systems. The article also briefly describes the outcome of authors own original works on the relationship between infections and schizophrenia, and their notice about possible immunomodulatory effects of antipsychoticsKey words: antipsychotics - immunity - infection - inflammation - mind - pain - schizophrenia.
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27914470/symptom-profiles-and-inflammatory-markers-in-moderate-to-severe-copd
#2
Huong Q Nguyen, Jerald R Herting, Kenneth C Pike, Sina A Gharib, Gustavo Matute-Bello, Soo Borson, Ruth Kohen, Sandra G Adams, Vincent S Fan
BACKGROUND: Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS: We conducted latent class analyses of three physical (dyspnea, fatigue, and pain) and two psychological symptoms (depression and anxiety) in 302 patients with moderate to severe COPD using baseline data from a longitudinal observational study of depression in COPD...
December 3, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27912936/effects-of-mind-body-exercises-on-the-physiological-and-psychosocial-well-being-of-individuals-with-parkinson-s-disease-a-systematic-review-and-meta-analysis
#3
REVIEW
JoJo Yan Yan Kwok, Kai Chow Choi, Helen Yue Lai Chan
OBJECTIVES: The effects of mind-body exercises on individuals with chronic illnesses have attracted increasing attention. However, little effort had been made to systematically review the effects of these mind-body exercises on individuals with Parkinson's disease (PD). This review aimed to appraise the current evidence of the effects of mind-body exercises on the physiological and psychological outcomes for the PD population. DESIGN: Systematic review and meta-analysis of randomized controlled trials...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27908212/are-crh-ngf-as-psychoneuroimmune-regulators-in-women-with-polycystic-ovary-syndrome
#4
F Z Zangeneh, M M Naghizadeh, M Bagheri, M Jafarabadi
PURPOSE: Polycystic ovary syndrome (PCOS) affects quality of life and can worsen anxiety and depression either due to the features of PCOS or due to the diagnosis of a chronic disease. Corticotrophin-releasing hormone (CRH) and nerves growth factor (NGF) are the modulator for the actions of the sympathetic nervous and immune systems. METHODS: In total, 171 women divided into two groups: study and control groups. Serum CRH, NGF, and interleukins: IL-1α. IL-1β, 17A, and TNFα were determined by ELISA Kits in both groups...
December 2, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27879043/uncovering-key-structural-features-of-an-enantioselective-peptide-catalyzed-acylation-utilizing-advanced-nmr-techniques
#5
Eliška Procházková, Andreas Kolmer, Julian Ilgen, Mira Schwab, Lukas Kaltschnee, Maic Fredersdorf, Volker Schmidts, Raffael C Wende, Peter R Schreiner, Christina M Thiele
We report on a detailed NMR spectroscopic study of the catalyst-substrate interaction of a highly enantioselective oligopeptide catalyst that is used for the kinetic resolution of trans-cycloalkane-1,2-diols via monoacylation. The extraordinary selectivity has been rationalized by molecular dynamics as well as density functional theory (DFT) computations. Herein we describe the conformational analysis of the organocatalyst studied by a combination of nuclear Overhauser effect (NOE) and residual dipolar coupling (RDC)-based methods that resulted in an ensemble of four final conformers...
November 23, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27876820/a-method-to-customize-population-specific-arrays-for-genome-wide-association-testing
#6
Erik A Ehli, Abdel Abdellaoui, Iryna O Fedko, Charlie Grieser, Sahar Nohzadeh-Malakshah, Gonneke Willemsen, Eco Jc de Geus, Dorret I Boomsma, Gareth E Davies, Jouke J Hottenga
As an example of optimizing population-specific genotyping assays using a whole-genome sequence reference set, we detail the approach that followed to design the Axiom-NL array which is characterized by an improved imputation backbone based on the Genome of the Netherlands (GoNL) reference sequence and, compared with earlier arrays, a more comprehensive inclusion of SNPs on chromosomes X, Y, and the mitochondria. Common variants on the array were selected to be compatible with the Illumina Psych Array and the Affymetrix UK Biobank Axiom array...
November 23, 2016: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/27870943/longitudinal-monitoring-of-heartbeat-dynamics-predicts-mood-changes-in-bipolar-patients-a-pilot-study
#7
Claudio Gentili, Gaetano Valenza, Mimma Nardelli, Antonio Lanatà, Gilles Bertschy, Luisa Weiner, Mauro Mauri, Enzo Pasquale Scilingo, Pietro Pietrini
OBJECTIVES: Recent research indicates that Heart Rate Variability (HRV) is affected in Bipolar Disorders (BD) patients. To determine whether such alterations are a mere expression of the current mood state or rather contain longitudinal information on BD course, we examined the potential influence of states adjacent in time upon HRV features measured in a target mood state. METHODS: Longitudinal evaluation of HRV was obtained in eight BD patients by using a wearable monitoring system developed within the PSYCHE project...
November 12, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27862747/ultrahigh-resolution-diffusion-ordered-spectroscopy
#8
Mohammadali Foroozandeh, Laura Castañar, Lucas G Martins, Davy Sinnaeve, Guilherme Dal Poggetto, Claudio F Tormena, Ralph W Adams, Gareth A Morris, Mathias Nilsson
Diffusion-ordered spectroscopy (DOSY) is an effective method for the analysis of intact mixtures, but the quality of results is critically limited by resolution in the NMR dimension. A new experiment integrating diffusion weighting into the PSYCHE method for pure shift NMR spectroscopy allows DOSY spectra to be measured with ultrahigh NMR resolution at improved sensitivity.
November 10, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27859181/the-analyst-s-narrative-function-inventing-a-possibility
#9
Maria Cecília Pereira da Silva
This article describes a psychic function common to analysts that was gradually revealed through clinical work with children. It is a psychic quality derived from function α, which involves analysts' capacity for reverie - their narrative function. The author presents two clinical situations where this function developed in the analytic field in relation to patients' difficulty in symbolizing. In the first case there was an early traumatic experience unavailable for representation. The analyst lent the patient her ability to represent and produced a narrative that made it possible to create a world of phantasies and transform nightmares into 'dreamable' dreams...
November 17, 2016: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/27859149/psyche-and-culture-perspectives-based-on-the-contributions-and-limits-of-ethnopsychiatry
#10
Rajaa Stitou
The unconscious often appears in the form of a question or answer to the difficult relationship between the psyche and culture, a difficulty that becomes exacerbated when we are dealing with cultural difference. This difficulty, evidenced for example by Freud's thoughts on Islam, reappears, albeit in a very different way, in ethnopsychiatric theory. The author discusses the blind spots of the binary logic of the unconscious present in the work of George Devereux, a logic that eventually leads him into the same trap he had himself criticized...
November 17, 2016: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/27772740/prolonged-release-fampridine-treatment-improved-subject-reported-impact-of-multiple-sclerosis-item-level-analysis-of-the-msis-29
#11
Claudio Gasperini, Raymond Hupperts, Jan Lycke, Christine Short, Manjit McNeill, John Zhong, Lahar R Mehta
Prolonged-release (PR) fampridine is approved to treat walking impairment in persons with multiple sclerosis (MS); however, treatment benefits may extend beyond walking. MOBILE was a phase 2, 24-week, double-blind, placebo-controlled exploratory study to assess the impact of 10mg PR-fampridine twice daily versus placebo on several subject-assessed measures. This analysis evaluated the physical and psychological health outcomes of subjects with progressing or relapsing MS from individual items of the Multiple Sclerosis Impact Scale (MSIS-29)...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27763673/jung-s-psychoid-concept-and-bion-s-proto-mental-concept-a-comparison
#12
Ann Addison
Jung and Bion both developed theoretical concepts propounding a deeply unknowable area of the psyche in which body and mind are undifferentiated and the individual has no distinct identity, from which a differentiated consciousness arises. In Jung's case, this is enshrined in his psychoid concept and the associated notion of synchronicity and, in Bion's case, in his proto-mental concept and his ideas on group dynamics. It is by means of these two concepts that Jung and Bion approach and locate a combined body-mind, a monism, in which body and mind are seen as different aspects of the same thing...
November 2016: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/27760134/audiovisual-interval-size-estimation-is-associated-with-early-musical-training
#13
Mary Kathryn Abel, H Charles Li, Frank A Russo, Gottfried Schlaug, Psyche Loui
Although pitch is a fundamental attribute of auditory perception, substantial individual differences exist in our ability to perceive differences in pitch. Little is known about how these individual differences in the auditory modality might affect crossmodal processes such as audiovisual perception. In this study, we asked whether individual differences in pitch perception might affect audiovisual perception, as it relates to age of onset and number of years of musical training. Fifty-seven subjects made subjective ratings of interval size when given point-light displays of audio, visual, and audiovisual stimuli of sung intervals...
2016: PloS One
https://www.readbyqxmd.com/read/27744473/-measuring-orofacial-pain
#14
R S G M Perez
Pain is a complex neuro-physiological phenomenon affecting mind and behaviour, and is in turn also affected by psyche and behaviour. Differences among individuals in modulation, interpretation and expression complicate the comparison of pain between patients. Pain is a subjective experience and can be expressed by the patient in many different ways. In addition, influential factors from a bio-psycho-social perspective have to be taken into consideration: the interaction among somatic, psychological and social factors determines the ultimate pain experience and pain behaviour...
October 2016: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/27741440/use-of-simulated-patients-to-develop-communication-skills-in-nursing-education-an-integrative-review
#15
REVIEW
Sharon MacLean, Michelle Kelly, Fiona Geddes, Phillip Della
BACKGROUND: Registered nurses are expected to communicate effectively with patients. To improve on this skill education programmes in both hospital and tertiary settings are increasingly turning to simulation modalities when training undergraduate and registered nurses. The roles simulated patients (SPs) assume can vary according to training purposes and approach. AIMS: The first aim is to analyse how SPs are used in nursing education to develop communication skills...
January 2017: Nurse Education Today
https://www.readbyqxmd.com/read/27727495/hadamard-homonuclear-broadband-decoupled-tocsy-nmr-improved-efficacy-in-detecting-long-range-chemical-shift-correlations
#16
Veera Mohana Rao Kakita, Ramakrishna V Hosur
The importance of Hadamard encoding pulses in one-dimensional pure shift yielded by the chirp excitation version of selective total correlation spectroscopy (1D PSYCHE-TOCSY) experiments is discussed for chemical-shift analysis of complex natural products at ultrahigh resolution. Herein, we adapted Hn Hadamard matrices to 1D PSYCHE-TOCSY and observed an overall circa square root of n-fold enhancement in the signal-to-noise (S/N) ratio when compared to conventional 1D PSYCHE-TOCSY recorded by refocusing only one spin at a time...
October 11, 2016: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/27717943/pediatric-pain-management-what-are-we-able-to-do-in-polish-emergency-medical-services
#17
Beata Rybojad, Mariusz Goniewicz, Daniel Sieniawski
Pain management in emergency medical care remains underestimated, especially in pediatric patients. This is due to neglecting the issue, lack of knowledge in the appropriate use of analgesics and finally- the fear of being criticized by physicians in hospital departments. Moreover, it is difficult to objectively assess a child with acute pain. Even experienced "adult" anesthesiologists wonder how to recognize if a child suffers strong pain or is just anxious. Many different pain scales are available and some of them may be used in emergency medical care...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27708823/what-are-health-professionals-intentions-toward-using-research-and-products-of-research-in-clinical-practice-a-systematic-review-and-narrative-synthesis
#18
Ben Appleby, Carolyn Roskell, William Daly
AIM: To explore health professionals' intentional behaviour and what determines their intention to use products of research in clinical practice. BACKGROUND: Trying to get research and products of research into clinical practice is an enduring problem. A clearer picture is emerging as to how individual practitioners respond toward practical problems of changing clinical practice, but this does not include health professionals' intentions to use products of research and what influences their intentions...
July 2016: Nursing Open
https://www.readbyqxmd.com/read/27693942/psych-verbs-the-linking-problem-and-the-acquisition-of-language
#19
Joshua K Hartshorne, Timothy J O'Donnell, Yasutada Sudo, Miki Uruwashi, Miseon Lee, Jesse Snedeker
In acquiring language, children must learn to appropriately place the different participants of an event (e.g., causal agent, affected entity) into the correct syntactic positions (e.g., subject, object) so that listeners will know who did what to whom. While many of these mappings can be characterized by broad generalizations, both within and across languages (e.g., semantic agents tend to be mapped onto syntactic subjects), not all verbs fit neatly into these generalizations. One particularly striking example is verbs of psychological state: The experiencer of the state can appear as either the subject (Agnes fears/hates/loves Bartholomew) or the direct object (Agnes frightens/angers/delights Bartholomew)...
December 2016: Cognition
https://www.readbyqxmd.com/read/27693903/reliability-and-validity-of-the-spanish-version-of-the-memorial-symptom-assessment-scale-in-oncology-patients
#20
Inés Llamas Ramos, Rocío Llamas Ramos, Ana María Martín Nogueras, Jorge Juan Alvarado Omenat, José Ignacio Calvo Arenillas, Emilio Fonseca Sánchez, María Cortés Rodríguez
CONTEXT: Memorial Symptom Assessment Scale (MSAS) is a multidimensional tool developed to evaluate frequency, severity and distress of common symptoms present in cancer patients. OBJECTIVE: To translate the original English version of MSAS and prove the reliability and validity of the Spanish version. METHODS: MSAS scale was translated into Spanish and administered to 246 cancer patients aged between 18 and 85. They attended the Day Hospital to receive chemotherapy...
September 29, 2016: Journal of Pain and Symptom Management
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