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https://www.readbyqxmd.com/read/29768597/anthropometric-changes-and-their-effects-on-cardiometabolic-risk-factors-in-rural-populations-in-brazil
#1
Tatiane Géa-Horta, Mark Anthony Beinner, Andrea Gazzinelli, Mariana Santos Felisbino Mendes, Gustavo Velasquez-Melendez
This article aims to evaluate associations between anthropometric changes in five years with lipid and blood pressure levels in Brazilian rural population. This longitudinal study evaluated 387 individuals aged 18 to 75 residents of two rural communities. Demographic, lifestyle, anthropometric, biochemical and hemodynamic characteristics were assessed in 2004 and repeated in 2009. Multivariate linear regression was used. Positive change in BMI was associated with increased diastolic blood pressure (DBP) (β = 0...
May 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29768534/impact-of-dexmedetomidine-on-hemodynamics-in-rabbits
#2
Jianjun Ren, Changfa Li, Shuxian Ma, Jiangli Wu, Yanjie Yang
PURPOSE: To evaluate the effects of single intravenous administration of Dexmedetomidine (DEX) on hemodynamics in rabbits. METHODS: A total of 32 New Zealand white rabbits were randomly divided into the control group (Group C), Group D1 (2.75 μg/kg), Group D2 (5.5 μg/kg), and Group D3 (8.25 μg/kg) to compare systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), central venous pressure (CVP), left ventricular systolic pressure (LVSP), left ventricular end-stage diastolic pressure (LVEDP), left ventricular developmental pressure (LVDP), +dp/dtmax, -dp/dtmax, and t-dp/dtmax at different time points...
April 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29768300/the-hemodynamic-response-to-constant-dobutamine-infusion-the-effect-of-adrb1-389-polymorphism-and-sex
#3
Dotan Yogev, Maamoun Basheer, Amichai Perlman, Simcha Blotnick, Yoseph Caraco, Mordechai Muszkat
OBJECTIVES: Prolonged activation of the β-1 adrenergic receptor (ADRB1) is associated with receptor desensitization. This process has been suggested to have important pathophysiological and clinical implications in conditions such as congestive heart failure. The contribution of genetic factors to this process is a patient of ongoing research. We have previously shown that the ADRB1 389 polymorphism affects the response to incremental dose infusion of the ADRB agonist dobutamine. The aim of the current study was to determine whether the ADRB1 389 polymorphism affects the hemodynamic response to constant dose infusion of dobutamine in healthy patients...
June 2018: Pharmacogenetics and Genomics
https://www.readbyqxmd.com/read/29767851/risk-factors-for-vitamin-d-deficiency-in-sickle-cell-disease
#4
Jin Han, Xu Zhang, Santosh L Saraf, Michel Gowhari, Robert E Molokie, Johara Hassan, Shivi Jain, Binal N Shah, Taimur Abbasi, Roberto F Machado, Victor R Gordeuk
Vitamin D deficiency (VDD), 25-OHD levels <20 ng/ml, is prevalent among patients with sickle cell disease (SCD) and is linked to acute and chronic pain and bone fracture in this population. There is limited literature regarding VDD-associated risk factors for SCD. We examined potential clinical and genomic parameters associated with VDD in 335 adults with SCD in a cross-sectional study. VDD was present in 65% of adult SCD patients, and 25-OHD levels independently and positively correlated with older age (P < 0·001) and vitamin D supplementation (P < 0·001)...
May 16, 2018: British Journal of Haematology
https://www.readbyqxmd.com/read/29767674/optimal-blood-pressure-in-elderly-hypertensive-subjects-a-korean-national-health-insurance-service-health-examinee-cohort-study
#5
Jiwon Seo, Chan Joo Lee, Jinseub Hwang, Jaewon Oh, Sang-Hak Lee, Seok-Min Kang, Donghoon Choi, Hyeon-Chang Kim, Sungha Park
Background: To describe the association between mean blood pressure (BP) and clinical outcomes and to investigate the optimal BP in elderly hypertensive subjects. Methods: This study used the National Health Insurance Service health examinee sample cohort. Subjects aged >60 years with a new diagnosis of hypertension from 2003 to 2006 were selected. Patients with previous major cardiovascular events were excluded. The remaining 23,523 subjects were divided into 3 groups according to mean systolic BP (SBP) and diastolic BP (DBP): average SBP <130 mmHg (n=6,893), 130-140 mmHg (n=8,676), and ≥140 mmHg (n=7,954) or 2) average DBP <80 mmHg (n=9,273), 80-90 mmHg (n=11,607), and ≥90 mmHg (n=2,643)...
May 15, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29767671/significance-of-an-increase-in-diastolic-blood-pressure-during-a-stress-test-in-terms-of-comorbidities-and-long-term-total-and-cv-mortality
#6
Nóra Sydó, Tibor Sydó, Karina A Gonzalez Carta, Nasir Hussain, Béla Merkely, Joseph G Murphy, Ray W Squires, Francisco Lopez-Jimenez, Thomas G Allison
Background: A decrease in diastolic blood pressure (DBP) with exercise is considered normal, but the significance of an increase in DBP has not been validated. Our aim was to determine the relationship of DBP increasing on a stress test regarding comorbidities and mortality. Methods: Our database was reviewed from 1993-2010 using the first stress test of a patient. Non-Minnesota residence, baseline CV disease, rest DBP <60 or >100 mmHg, and age <30 or ≥80 were exclusion criteria...
May 15, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29765674/photocatalytic-degradation-properties-of-%C3%AE-fe-2-o-3-nanoparticles-for-dibutyl-phthalate-in-aqueous-solution-system
#7
Yue Liu, Nan Sun, Jianshe Hu, Song Li, Gaowu Qin
The phthalate ester compounds in industrial wastewater, as kinds of environmental toxic organic pollutants, may interfere with the body's endocrine system, resulting in great harm to humans. In this work, the photocatalytic degradation properties of dibutyl phthalate (DBP) were investigated using α-Fe2 O3 nanoparticles and H2 O2 in aqueous solution system. The optimal parameters and mechanism of degradation were discussed by changing the morphology and usage amount of catalysts, the dosage of H2 O2 , pH value and the initial concentration of DBP...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29765328/long-term-consumption-of-cuban-policosanol-lowers-central-and-brachial-blood-pressure-and-improves-lipid-profile-with-enhancement-of-lipoprotein-properties-in-healthy-korean-participants
#8
Suk-Jeong Kim, Dhananjay Yadav, Hye-Jeong Park, Jae-Ryong Kim, Kyung-Hyun Cho
Metabolic syndrome is closely associated with higher risk of hypertension, cardiovascular disease (CVD), diabetes and stroke. The aim of the present study was to investigate the long-term effects of policosanol supplementation on blood pressure (BP) and the lipid profile in healthy Korean participants with pre-hypertension (systolic 120-139 mmHg, diastolic 85-89 mmHg). This randomized, double-blinded, and placebo-controlled trial included 84 healthy participants who were randomly assigned to three groups receiving 10 mg of policosanol, 20 mg of policosanol, or placebo for 24 weeks...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29762842/the-role-of-commonly-used-clinical-indicators-in-the-diagnosis-of-acute-heart-failure
#9
X-L Wang, J-M Lei, Y Yuan, L Feng, Y Ning, Y-F Liu
OBJECTIVE: Acute heart failure (AHF) is one of the most commonly seen clinical cases, with a high rate of re-hospitalization and mortality. AHF can be divided into two categories based on the systolic function of the left ventricle, which are heart failure with reduced ejection fraction (HFREF) and heart failure with preserved ejection fraction (HFPEF). Pathogenesis and treatment of the two are quite different. In this article we attempted to explore the value of combined use of clinical and laboratory indicators in the differential diagnosis of AHFREF and AHFPEF...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29760682/daily-gene-expression-rhythms-in-rat-white-adipose-tissue-do-not-differ-between-subcutaneous-and-intra-abdominal-depots
#10
Rianne van der Spek, Eric Fliers, Susanne E la Fleur, Andries Kalsbeek
White adipose tissue (WAT) is present in different depots throughout the body. Although all depots are exposed to systemic humoral signals, they are not functionally identical. Studies in clock gene knockout animals and in shift workers suggest that daily rhythmicity may play an important role in lipid metabolism. Differences in rhythmicity between fat depots might explain differences in depot function; therefore, we measured mRNA expression of clock genes and metabolic genes on a 3-h interval over a 24-h period in the subcutaneous inguinal depot and in the intra-abdominal perirenal, epididymal, and mesenteric depots of male Wistar rats...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29757049/prevalence-of-indicators-of-low-energy-availability-in-elite-female-sprinters
#11
Jennifer Sygo, Alexandra M Coates, Erik Sesbreno, Margo L Mountjoy, Jamie F Burr
Low energy availability (LEA), and subsequent relative energy deficiency in sport (RED-S), has been observed in endurance, aesthetic, and team sport athletes, with limited data on prevalence in athletes in short-burst activities such as sprinting. We examined prevalence of signs and symptoms of LEA in elite female sprinters at the start of the training season (PRE), and at the end of a 5-month indoor training period (POST). Four of 13 female sprinters (31%) presented at PRE testing with at least one primary (amenorrhea, low BMD, low FSH, LH, or estradiol, RMR ≤ 29kcal/kg FFM, Low Energy Availability in Females Questionnaire (LEAF-Q) score ≥8) and one secondary indicator of LEA (fasting blood glucose < 4mmol/L, free triiodothyronine < 3...
May 14, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29755411/time-of-day-effects-on-metabolic-and-clock-related-adjustments-to-cold
#12
Frederico Sander Mansur Machado, Zhi Zhang, Yan Su, Paul de Goede, Remi Jansen, Ewout Foppen, Cândido Celso Coimbra, Andries Kalsbeek
Background: Daily cyclic changes in environmental conditions are key signals for anticipatory and adaptive adjustments of most living species, including mammals. Lower ambient temperature stimulates the thermogenic activity of brown adipose tissue (BAT) and skeletal muscle. Given that the molecular components of the endogenous biological clock interact with thermal and metabolic mechanisms directly involved in the defense of body temperature, the present study evaluated the differential homeostatic responses to a cold stimulus at distinct time-windows of the light/dark-cycle...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29755228/effect-of-1-week-yoga-based-residential-program-on-cardiovascular-variables-of-hypertensive-patients-a-comparative-study
#13
Kashinath G Metri, Balaram Pradhan, Amit Singh, H R Nagendra
Introduction: Hypertension (HTN) is an important public health concern and a leading cause of morbidity and mortality worldwide. Yoga is a form of mind-body medicine shown to be effective in controlling blood pressure (BP) and reduces cardiac risk factors in HTN. Integrated approach of Yoga therapy (IAYT) is a residential yoga-based lifestyle intervention proven to be beneficial in several health conditions. Aim: To study the efficacy of 1 week of residential IAYT intervention on cardiovascular parameters in hypertensive patients...
May 2018: International Journal of Yoga
https://www.readbyqxmd.com/read/29754908/an-operational-definition-of-shats-systemic-hemodynamic-atherosclerotic-syndrome-role-of-arterial-stiffness-and-blood-pressure-variability-in-elderly-hypertensive-subjects
#14
Angelo Scuteri, Valentina Rovella, Danilo Alunni Fegatelli, Manfredi Tesauro, Marco Gabriele, Nicola Di Daniele
BACKGROUND: CV risk exponentially increases as the number of damaged organs increases The Systemic Hemodynamic Atherosclerotic Syndrome (SHATS) represents a novel conceptualization of the CV continuum focusing on simultaneous multi-organ alteration. This is the first study operationally defining SHATS and aimed at identifying its determinants. METHODS: Left Ventricular Hypertrophy (echocardiography), Common Carotid Artery plaque and increased thickness (ultrasound), and Chronic Kidney Disease (estimated Glomerular Filtration Rate) indexed selective target organ damage...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29753975/the-dependence-of-chlorine-decay-and-dbp-formation-kinetics-on-pipe-flow-properties-in-drinking-water-distribution
#15
Yingying Zhao, Y Jeffrey Yang, Yu Shao, Jill Neal, Tuqiao Zhang
Simultaneous chlorine decay and disinfection byproduct (DBP) formation have been discussed extensively because of their regulatory and operational significance. This study further examines chemical reaction variability in the water quality changes under various hydrodynamic conditions in drinking water distribution. The variations of kinetic constant for overall chlorine decay (kE ) and trihalomethane (THM) formation were determined under stagnant to turbulent flows using three devices of different wall demand and two types of natural organic matters (NOM) in water...
April 27, 2018: Water Research
https://www.readbyqxmd.com/read/29753739/effect-of-cisplatin-on-the-clock-genes-expression-in-the-liver-heart-and-kidney
#16
Bei-Bei Cao, Dengfeng Li, Xiaoliang Xing, Yaguang Zhao, Kunyang Wu, Fang Jiang, Wei Yin, Jia-Da Li
Cisplatin is a platinum-based chemotherapy drug is widely used to treat various types of malignancies. Although the involvement of circadian clock in cisplatin metabolism and excretion has been reported, the effect of cisplatin on circadian rhythm remains unclear. In the present study, we investigated the effects of cisplatin on clock genes expression in mouse peripheral tissues. Cisplatin induced severe nephrotoxicity, as revealed by the significant increase of blood urea nitrogen and serum creatinine levels...
May 10, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29752165/hypertension-and-its-correlate-with-general-and-central-adiposity-a-study-among-urban-population-of-delhi
#17
Meenal Dhall, Kshetrimayum Surmala Devi, Nilupher, Urvashi Gupta, Renu Tyagi, Satwanti Kapoor
AIM: Study aims to assess the association of various adiposity markers with blood pressure levels. STUDY DESIGN: The present study was a cross-sectional study conducted in Delhi. A total of 568 (males- 250, females- 318) participants aged 20-55 years were enrolled for the study. RESULT: Mean height (167.35 ± 7.59) and weight (73.76 ± 15.08) was found to be significantly higher in males. Mean values of minimum waist circumference (183...
May 5, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29751936/effect-of-vitamin-d-on-the-variability-of-blood-pressure-in-premenopausal-and-menopausal-hypertensive-women-in-the-area-of-blida-algeria
#18
A Bachir Cherif, M Temmar, S Bennouar, A Bouamra, A Taleb, A Bouraghda, M T Bouafia
OBJECTIVE: To evaluate the effect of 25 (OH) vitamin D supplementation on blood pressure (BP) variability in hypertensive women in the pre-menopausal and post-menopausal periods. MATERIALS AND METHODS: 881 hypertensive women prospectively followed for an interventional study between January 2016 and September 2017, in specialized consultation at the department of internal medicine at the Blida University Hospital (Algeria). Four hundred and thiry nine premenopausal women (group I) and 442 menopausal women (group II)...
May 8, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29751583/blood-pressure-lowering-effect-of-cuban-policosanol-is-accompanied-by-improvement-of-hepatic-inflammation-lipoprotein-profile-and-hdl-quality-in-spontaneously-hypertensive-rats
#19
Kyung-Hyun Cho, Dhananjay Yadav, Suk-Jeong Kim, Jae-Ryong Kim
We investigated the antihypertensive effect of policosanol on spontaneously hypertensive rats (SHR). For this, we analyzed blood pressure, blood lipid, and lipoprotein properties in male SHR after consumption of Cuban policosanol (PCO). The experimental groups were as follows: normotensive Wistar Kyoto (WKY) control, SHR group fed normal diet (ND), SHR group fed 20 mg of PCO, SHR group fed 100 mg of PCO, and SHR group fed 200 mg of PCO per kg of body weight. After eight weeks, the SHR control group showed gradual increases up to 21% in systolic blood pressure (SBP) and diastolic blood pressure (DBP) compared with values at week 0...
May 3, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29751268/catalytic-ozonation-of-di-n-butyl-phthalate-degradation-using-manganese-ferrite-reduced-graphene-oxide-nanofiber-as-catalyst-in-the-water
#20
Yueming Ren, Huiyu Zhang, Hongze An, Ying Zhao, Jing Feng, Lili Xue, Tianzhu Luan, Zhuangjun Fan
Graphene oxide doping MnFe2 O4 (rGO-MnFe2 O4 ) nanofibers were synthesized via electrospinning method and applied to degrade refractory Di-n-butyl Phthalate (DBP) by catalytic ozonation in the water. Characterizations and effect of various conditions on DBP removal were investigated. Meanwhile, the mechanism of enhanced DBP degradation after rGO incorporation was explored intensively. Results showed that 5 wt% GO doping into MnFe2 O4 improved the concentration of surface hydroxyl sites (SHSC), the oxidation potential, material diffusion and charge electronic transfer ability in contrast to MnFe2 O4 nanofibers, resulting in significantly enhanced DBP degradation compared with ozonation alone...
April 18, 2018: Journal of Colloid and Interface Science
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