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https://www.readbyqxmd.com/read/29334639/vestibular-schwannoma-and-hearing-preservation-usefulness-of-level-specific-ce-chirp-abr-monitoring-a-retrospective-study-on-25-cases-with-preoperative-socially-useful-hearing
#1
Luciano Mastronardi, Ettore Di Scipio, Guglielmo Cacciotti, Raffaelino Roperto
BACKGROUND AND OBJECTIVES: Decision-making regarding the therapy of vestibular schwannoma (VS) changed over the last decades, during which curative microsurgery has been promoted. Goals of VS microsurgery are: extensive resection, facial nerve (FN) preservation and, in selected cases, hearing preservation (HP). The aim of this study is to evaluate postoperative HP with reference to tumor size in patients operated on with Level Specific (LS)-CE-Chirp® ABR monitoring. PATIENTS AND METHODS: Twentyfive consecutive patients with socially useful hearing (SUH) underwent VS microneurosurgery by retrosigmoid (RS) approach...
January 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29334296/the-experience-of-hearing-loss-journey-through-aural-rehabilitation
#2
Christopher Lind
No abstract text is available yet for this article.
January 15, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29334277/validation-of-dpoae-screening-conducted-by-village-health-workers-in-a-rural-community-with-real-time-click-evoked-tele-auditory-brainstem-response
#3
Vidya Ramkumar, C S Vanaja, James W Hall, K Selvakumar, Roopa Nagarajan
OBJECTIVE: This study assessed the validity of DPOAE screening conducted by village health workers (VHWs) in a rural community. Real-time click evoked tele-auditory brainstem response (tele-ABR) was used as the gold standard to establish validity. DESIGN: A cross-sectional design was utilised to compare the results of screening by VHWs to those obtained via tele-ABR. Study samples: One hundred and nineteen subjects (0 to 5 years) were selected randomly from a sample of 2880 infants and young children who received DPOAE screening by VHWs...
January 15, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29332169/measuring-cochlear-duct-length-in-asian-population-worth-giving-a-thought
#4
Mohnish Grover, Shitanshu Sharma, Shashank Nath Singh, Tanmaya Kataria, Rajendra Singh Lakhawat, Man Prakash Sharma
INTRODUCTION: The anatomy of the cochlea forms the basis for a successful cochlear implantation. Cochlear duct length (CDL) is defined as the length of the scala media as measured from the middle of the round window to helicotrema. Preoperative measurement of CDL is particularly important when precise intracochlear electrode array placement is desired. It can be done both histologically and radiologically. Preoperative high-resolution computed tomography (HRCT) scan which forms an integral part of cochlear implant workup is a useful tool to calculate CDL using 3D reconstructions...
January 13, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29332068/the-role-of-preoperative-steroids-for-hearing-preservation-cochlear-implantation-results-of-a-randomized-controlled-trial
#5
Jafri Kuthubutheen, Samidha Joglekar, Leah Smith, Lendra Friesen, Kari Smilsky, Tara Millman, Amy Ng, David Shipp, Harvey Coates, Christoph Arnoldner, Julian Nedzelski, Joseph Chen, Vincent Lin
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI). METHODS: This is a randomized controlled trial involving 30 postlingual deaf CI patients. Subjects had preoperative thresholds of better than or equal to 80 dB at 125 and 250 Hz, and better than or equal to 90 dB at 500 and 1,000 Hz. The subjects were randomized to a control group, an oral steroid group (receiving 1 mg/kg/day of prednisolone for 6 days prior to surgery), or a transtympanic steroid group (receiving a single dose of 0...
January 13, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29331749/paediatric-dysgerminoma-results-of-three-consecutive-french-germ-cell-tumours-clinical-studies-tgm-85-90-95-with-late-effects-study
#6
Gwénaëlle Duhil de Bénazé, Hélène Pacquement, Cécile Faure-Conter, Catherine Patte, Daniel Orbach, Nadège Corradini, Claire Berger, Hélène Sudour-Bonnange, Cécile Vérité, Hélène Martelli, Brice Fresneau
METHODS: French patients (≤18years) treated for dysgerminoma between 1985 and 2005 in TGM-85, 90, 95 protocols were included. Treatment was based on primary unilateral oophorectomy followed by prophylactic lymph node irradiation (1985-1998) or a wait-and-see strategy (1998-2005) for localised completely resected tumours (pS1) or by platinum-based chemotherapy for advanced diseases. RESULTS: Forty-eight patients (median age 12.8 years) were included. Six patients had gonadal dysgenesis...
January 10, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29331590/setting-mechanism-of-a-new-injectable-dicalcium-phosphate-dihydrate-dcpd-forming-cement
#7
Weiping Ren, Wei Song, Sally Yurgelevic, David C Markel
We previously described the gelation mechanism of calcium polyphosphate (CPP) in the presence of water. In this study, we developed novel and injectable poly-dicalcium phosphate dihydrate (P-DCPD) forming cement by the reaction of acidic CPP gel with alkali tetracalcium phosphate (TTCP). The setting reaction mechanism of P-DCPD is due to the intermolecular interaction between CPP gel and TTCP that was supported by XRD, AFM, Raman spectra analysis and SEM. The setting mechanism of P-DCPD is completely different from the classical calcium phosphate cement (CPC) that achieves crystallization by monophosphates reaction...
January 4, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29331570/meningeal-marginal-zone-b-cell-lymphoma-the-meningioma-trap
#8
Alexandre Villeneuve, François Rubin, Pierre Bonfils
OBJECTIVE: To report a case of marginal zone MALT lymphoma of the temporal dura mater, initially mistaken for temporal meningioma. CASE REPORT: A 60-year-old immunocompetent woman, followed for more than 10 years for temporal meningioma causing vertigo and mixed hearing loss, presented with cervical lymphadenopathy, revealing marked progression of an intracranial lesion, leading to a diagnosis of marginal zone MALT lymphoma based on histological examination of a cervical lymph node...
January 10, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29331482/genetic-basis-of-hearing-loss-in-spanish-hispanic-and-latino-populations
#9
REVIEW
Rahul Mittal, Amit P Patel, Desiree Nguyen, Debbie R Pan, Vasanti M Jhaveri, Jason R Rudman, Arjuna Dharmaraja, Denise Yan, Yong Feng, Prem Chapagain, David J Lee, Susan H Blanton, Xue Zhong Liu
Hearing loss (HL) is the most common neurosensory disorder affecting humans. The screening, prevention and treatment of HL require a better understanding of the underlying molecular mechanisms. Genetic predisposition is one of the most common factors that leads to HL. Most HL studies include few Spanish, Hispanic and Latino participants, leaving a critical gap in our understanding about the prevalence, impact, unmet health care needs, and genetic factors associated with hearing impairment among Spanish, Hispanic and Latino populations...
January 10, 2018: Gene
https://www.readbyqxmd.com/read/29331307/risk-factors-of-sensorineural-hearing-loss-in-patients-with-unilateral-safe-chronic-suppurative-otitis-media
#10
Abd Elrheem Ahmed Singer, Osama G Abdel-Naby Awad, Rafeek Mohamed Abd El-Kader, Ahmed Rabeh Mohamed
PURPOSE: Chronic suppurative otitis media (CSOM) is the major cause of hearing impairment, especially conductive hearing loss. Few patients also had sensorineural component, the sensorineural hearing loss (SNHL) in CSOM is controversial, especially for safe mucosal type. This study aims to assess the relationship between the frequency of SNHL development in patients with safe mucosal CSOM and its relation to patient's age, sex, duration of disease, size of perforation and different audiological findings...
January 5, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29331002/genetics-of-human-hereditary-hearing-impairment
#11
Rahat Meena, Muhammad Ayub
Hereditary hearing impairment is heterogeneous type of disorder which can be caused due to environmental as well as genetical factors. Two distinct types of hereditary hearing loss are syndromic or non-syndromic. Non-syndromic hearing loss is further categorized as autosomal recessive, autosomal dominant, X-linked and mitochondrial deafness. Autosomal recessive occurs more frequently as compared to autosomal dominant. Mutations in various genes are responsible for hereditary hearing impairment. To date, about 99 autosomal recessives and 67 autosomal dominant genes for deafness have been discovered...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330883/genotype-phenotype-correlations-in-individuals-with-pathogenic-rere-variants
#12
Valerie K Jordan, Brieana Fregeau, Xiaoyan Ge, Jessica Giordano, Ronald J Wapner, Tugce B Balci, Melissa T Carter, John A Bernat, Amanda N Moccia, Anshika Srivastava, Donna M Martin, Stephanie L Bielas, John Pappas, Melissa D Svoboda, Marlène Rio, Nathalie Boddaert, Vincent Cantagrel, Andrea M Lewis, Fernando Scaglia, Jennefer N Kohler, Jonathan A Bernstein, Annika M Dries, Jill A Rosenfeld, Colette DeFilippo, Willa Thorson, Yaping Yang, Elliott H Sherr, Weimin Bi, Daryl A Scott
Heterozygous variants in the arginine-glutamic acid dipeptide repeats gene (RERE) have been shown to cause neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH). Here we report nine individuals with NEDBEH who carry partial deletions or deleterious sequence variants in RERE. These variants were found to be de novo in all cases in which parental samples were available. An analysis of data from individuals with NEDBEH suggests that point mutations affecting the Atrophin-1 domain of RERE are associated with an increased risk of structural eye defects, congenital heart defects, renal anomalies and sensorineural hearing loss when compared to loss-of-function variants that are likely to lead to haploinsufficiency...
January 13, 2018: Human Mutation
https://www.readbyqxmd.com/read/29330858/long-term-outcomes-of-cochlear-implantation-in-patients-with-high-frequency-hearing-loss
#13
J Thomas Roland, Bruce J Gantz, Susan B Waltzman, Aaron J Parkinson
OBJECTIVE: To demonstrate the long-term benefits of implantation in patients with high-frequency sensorineural hearing loss, this report provides 5-year follow-up on a group of implant recipients who were subjects of the Cochlear™ Nucleus® Hybrid™ L24 Implant System pivotal clinical study. METHODS: The results of three related clinical studies were compiled to provide outcome data after 1, 3, and 5 years of implant use in a group of subjects who presented with preoperative high-frequency hearing loss and were implanted with a Nucleus Hybrid L24 (Cochlear Ltd...
January 13, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29330597/inpatient-treatment-of-patients-with-idiopathic-sudden-sensorineural-hearing-loss-a-population-based-healthcare-research-study
#14
Anne Heuschkel, Katharina Geißler, Daniel Boeger, Jens Buentzel, Dirk Esser, Kerstin Hoffmann, Peter Jecker, Andreas Mueller, Gerald Radtke, Orlando Guntinas-Lichius
PURPOSE: The aim was to determine inpatient treatment rates of idiopathic sudden sensorineural hearing loss (ISSNHL) with focus on diagnostics, treatment, and outcome. METHODS: A retrospective population-based study in the federal state Thuringia in 2011 and 2012 was performed on all 490 inpatients (51% females, median age: 60 years) treated for ISSNHL (Median duration: 7 days). The association between analyzed parameters and the probability of recovery was tested using univariable and multivariable statistics...
January 12, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29330554/accuracy-of-a-screening-tool-for-early-identification-of-language-impairment
#15
Noëlle Uilenburg, Karin Wiefferink, Paul Verkerk, Margot van Denderen, Carla van Schie, Anne-Marie Oudesluys-Murphy
Purpose: A screening tool called the VTO Language Screening Instrument (VTO-LSI) was developed to enable more uniform and earlier detection of language impairment. This report, consisting of 2 retrospective studies, focuses on the effects of using the VTO-LSI compared to regular detection procedures. Method: Study 1 retrospectively compared VTO-LSI with regular detection procedures. Outcome measure was the detection rate of language impairment among 24-month-old children...
January 12, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29330553/remote-microphone-system-use-at-home-impact-on-caregiver-talk
#16
Carlos R Benítez-Barrera, Gina P Angley, Anne Marie Tharpe
Purpose: The purpose of this study was to investigate the effects of home use of a remote microphone system (RMS) on the spoken language production of caregivers with young children who have hearing loss. Method: Language Environment Analysis recorders were used with 10 families during 2 consecutive weekends (RMS weekend and No-RMS weekend). The amount of talk from a single caregiver that could be made accessible to children with hearing loss when using an RMS was estimated using Language Environment Analysis software...
January 12, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29330315/outcome-of-preterm-infants-with-postnatal-cytomegalovirus-infection
#17
Julia Gunkel, Linda S de Vries, Marian Jongmans, Corine Koopman-Esseboom, Ingrid C van Haastert, Maria C J Eijsermans, Carolien van Stam, Bert G A van Zanten, Tom F W Wolfs, Joppe Nijman
OBJECTIVES: To assess whether preterm infants with postnatal cytomegalovirus infection develop neurologic sequelae in early childhood. METHODS: Infants <32 weeks' gestation were prospectively screened for cytomegalovirus (CMV) at term-equivalent age. Neurodevelopment was compared between CMV-positive and CMV-negative infants by using the Griffiths Mental Development Scales (GMDS) at 16 months' corrected age (CA); the Bayley Scales of Infant and Toddler Development, Third Edition or the GMDS at 24 to 30 months' CA; and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition and Movement Assessment Battery for Children, Second Edition at 6 years of age...
January 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29330026/sound-shock-response-in-larval-zebrafish-a-convenient-and-high-throughput-assessment-of-auditory-function
#18
Xiuyun Liu, Jia Lin, Yinglan Zhang, Ning Guo, Qiang Li
Given that hearing ability can be challenged in diverse ways, it is necessary to develop an easily conducted, high-throughput method for assessing potential auditory risks. Measuring the acoustic startle response (ASR) has become a critical behavioral method in hearing research using zebrafish (Danio rerio). In this study, changes in the activity of zebrafish larvae (10 days post fertilization (dpf)) due to exposure to a sudden easily-generated broad-band noise were automatically and objectively recorded and analyzed without building sophisticated equipments...
January 9, 2018: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29329983/attenuation-of-noise-induced-hyperactivity-in-the-dorsal-cochlear-nucleus-by-pre-treatment-with-mk-801
#19
M W Criddle, D A Godfrey, J A Kaltenbach
It has previously been hypothesized that hyperactivity of central auditory neurons following exposure to intense noise is a consequence of synaptic alterations. Recent studies suggest the involvement of NMDA receptors in the induction of this hyperactive state. NMDA receptors can mediate long term changes in the excitability of neurons through their involvement in excitotoxic injury and long term potentiation and depression. In this study, we examined the effect of administering an NMDA receptor blocker on the induction of hyperactivity in the dorsal cochlear nucleus (DCN) following intense sound exposure...
January 9, 2018: Brain Research
https://www.readbyqxmd.com/read/29329660/cochlea-ct-radiomics-predicts-chemoradiotherapy-induced-sensorineural-hearing-loss-in-head-and-neck-cancer-patients-a-machine-learning-and-multi-variable-modelling-study
#20
Hamid Abdollahi, Shayan Mostafaei, Susan Cheraghi, Isaac Shiri, Seied Rabi Mahdavi, Anoshirvan Kazemnejad
OBJECTIVES: Immediately or after head-and-neck (H&N) cancer chemoradiotherapy (CRT), patients may undergone significant sensorineural hearing loss (SNHL) which could affect their quality of life. Radiomic feature analysis is proposed to predict SNHL induced by CRT. MATERIAL AND METHODS: 490 image features of 94 cochlea from 47 patients treated with three dimensional conformal RT (3DCRT) for different H&N cancers were extracted from CT images. Different machine learning (ML) algorithms and also least absolute shrinkage and selection operator (LASSO) penalized logistic regression were implemented on radiomic features for feature selection, classification and prediction...
January 9, 2018: Physica Medica: PM
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