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https://www.readbyqxmd.com/read/28527575/coup-tf-genes-human-diseases-and-the-development-of-the-central-nervous-system-in-murine-models
#1
Xiong Yang, Su Feng, Ke Tang
COUP-TFI and -TFII are members of the steroid/thyroid nuclear receptor superfamily. Recent clinical studies reveal that COUP-TFI gene mutations are associated with Bosch-Boonstra-Schaaf optic atrophy syndrome displaying symptoms of optic atrophy, intellectual disability, hypotonia, seizure, autism spectrum disorders, oromotor dysfunction, thin corpus callosum, or hearing defects, and COUP-TFII gene mutations lead to congenital heart defects and/or congenital diaphragmatic hernia with developmental delay and mental defects...
2017: Current Topics in Developmental Biology
https://www.readbyqxmd.com/read/28527538/masking-release-with-changing-fundamental-frequency-electric-acoustic-stimulation-resembles-normal-hearing-subjects
#2
Alice Barbara Auinger, Dominik Riss, Rudolfs Liepins, Tobias Rader, Tilman Keck, Thomas Keintzel, Alexandra Kaider, Wolf-Dieter Baumgartner, Wolfgang Gstoettner, Christoph Arnoldner
It has been shown that patients with electric acoustic stimulation (EAS) perform better in noisy environments than patients with a cochlear implant (CI). One reason for this could be the preserved access to acoustic low-frequency cues including the fundamental frequency (F0). Therefore, our primary aim was to investigate whether users of EAS experience a release from masking with increasing F0 difference between target talker and masking talker. The study comprised 29 patients and consisted of three groups of subjects: EAS users, CI users and normal-hearing listeners (NH)...
May 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28527478/-translation-cultural-adaptation-and-validation-of-the-satisfaction-with-amplification-in-daily-life-scale-for-european-portuguese
#3
Luis Roque Dos Reis, Mariana Donato, Rita Sousa, Pedro Escada
INTRODUCTION: The scale Satisfaction with Amplification in Daily Life uses a simple and easily administered questionnaire to evaluate the adaptation of individuals to their hearing aids. The objective of this study is to validate the scale for European Portuguese speakers, by means of translation and cultural adaptation of the questionnaire. The study includes an evaluation of reproducibility and a description of the results of the administration of the questionnaire to patients fitted with hearing aids...
February 27, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28527170/oculo-otological-manifestations-in-a-case-of-granulomatosis-with-polyangiitis
#4
Archana Sonawale, Anjali Rajadhyaksha, Shreepriya Mangalgi
A 44 year old lady presented with acute onset of loss of vision in the right eye and cough with mucopurulent expectoration for two months. Ophthalmic examination revealed central retinal artery occlusion (CRAO). Chest radiograph showed multiple cavitatory nodules with fluid levels. Sputum was negative for AFB and ANCA was strongly positive suggestive of a diagnosis of Granulomatosis with Polyangiitis (GPA). Within the next few weeks the patient had rapid detenoration due to left eye CRAO, progressive bilateral hearing loss, facial palsy and retro orbital mass...
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28527079/endolymphatic-hydrops-in-idiopathic-intracranial-hypertension-prevalence-and-clinical-outcome-after-lumbar-puncture-preliminary-data
#5
Angelo Ranieri, Michele Cavaliere, Stefania Sicignano, Pietro Falco, Federico Cautiero, Roberto De Simone
Idiopathic intracranial hypertension is characterized by raised intracranial pressure (ICP) without any underlying pathology, presenting with (IIH) or without papilledema (IIHWOP). Headache, often on daily basis, is the most frequent symptom. Among audiovestibular symptoms, tinnitus and dizziness are commonly reported, while vertigo and hearing impairment are infrequent reports. Endolymphatic hydrops (ELH) is the typical histopathologic feature of Ménière disease, a condition featured by episodes of vertigo, dizziness, fluctuating hearing loss, tinnitus, and aural fullness...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526871/electro-tactile-stimulation-enhances-cochlear-implant-speech-recognition-in-noise
#6
Juan Huang, Benjamin Sheffield, Payton Lin, Fan-Gang Zeng
For cochlear implant users, combined electro-acoustic stimulation (EAS) significantly improves the performance. However, there are many more users who do not have any functional residual acoustic hearing at low frequencies. Because tactile sensation also operates in the same low frequencies (<500 Hz) as the acoustic hearing in EAS, we propose electro-tactile stimulation (ETS) to improve cochlear implant performance. In ten cochlear implant users, a tactile aid was applied to the index finger that converted voice fundamental frequency into tactile vibrations...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526828/gender-differences-in-the-association-between-moderate-alcohol-consumption-and-hearing-threshold-shifts
#7
Yuan-Yung Lin, Hsin-Chien Chen, Wen-Sen Lai, Li-Wei Wu, Chih-Hung Wang, Jih-Chin Lee, Tung-Wei Kao, Wei-Liang Chen
Hearing loss is a global public health problem with a high prevalence, significantly impairing communication and leading to a decrease in the quality of life. The association between moderate alcohol consumption (MAC) and hearing impairment has been addressed in several studies with inconsistent results. The intent of our study is to clarify the correlation between MAC and the hearing threshold and further investigate the interplay between MAC and the hearing threshold categorized by gender. The study included 4,075 participants aged 20-69 years from the 1999-2004 data of National Health and Nutrition Examination Survey (NHANES)...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526676/endometriosis-research-should-aim-to-improve-diagnosis-and-halt-progression-meeting-hears
#8
Susan Mayor
No abstract text is available yet for this article.
May 18, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28526588/adam10-and-%C3%AE-secretase-regulate-sensory-regeneration-in-the-avian-vestibular-organs
#9
Mark E Warchol, Jennifer Stone, Matthew Barton, Jeffrey Ku, Rose Veile, Nicolas Daudet, Michael Lovett
The loss of sensory hair cells from the inner ear is a leading cause of hearing and balance disorders. The mammalian ear has a very limited ability to replace lost hair cells, but the inner ears of non-mammalian vertebrates can spontaneously regenerate hair cells after injury. Prior studies have shown that replacement hair cells are derived from epithelial supporting cells and that the differentiation of new hair cells is regulated by the Notch signaling pathway. The present study examined molecular influences on regeneration in the avian utricle, which has a particularly robust regenerative ability...
May 16, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28526550/impact-of-first-eye-versus-second-eye-cataract-surgery-on-visual-function-and-quality-of-life
#10
Nakul S Shekhawat, Michael V Stock, Elizabeth F Baze, Mary K Daly, David E Vollman, Mary G Lawrence, Amy S Chomsky
PURPOSE: To compare the impact of first eye versus second eye cataract surgery on visual function and quality of life. DESIGN: Cohort study. PARTICIPANTS: A total of 328 patients undergoing separate first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the United States. Patients with previous ocular surgery, postoperative endophthalmitis, postoperative retinal detachment, reoperation within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug abuse were excluded...
May 16, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28525626/skin-pigmentation-and-risk-of-hearing-loss-in-women
#11
Brian M Lin, Wen-Qing Li, Sharon G Curhan, Konstantina M Stankovic, Abrar A Qureshi, Gary C Curhan
Black individuals have a lower risk of hearing loss than do whites, possibly because of differences in cochlear melanocytes. Previous studies have suggested that darker-skinned individuals tend to have more inner ear melanin, and cochlear melanocytes are important in generating the endocochlear potential. We investigated the relationship between self-reported hearing loss and skin pigmentation by using hair color, skin tanning ability, and skin reaction to prolonged sun exposure as surrogate measures of pigmentation among 49,323 white women in the Nurses' Health Study...
May 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28522981/perception-of-leitmotives-in-richard-wagner-s-der-ring-des-nibelungen
#12
David J Baker, Daniel Müllensiefen
The music of Richard Wagner tends to generate very diverse judgments indicative of the complex relationship between listeners and the sophisticated musical structures in Wagner's music. This paper presents findings from two listening experiments using the music from Wagner's Der Ring des Nibelungen that explores musical as well as individual listener parameters to better understand how listeners are able to hear leitmotives, a compositional device closely associated with Wagner's music. Results confirm findings from a previous experiment showing that specific expertise with Wagner's music can account for a greater portion of the variance in an individual's ability to recognize and remember musical material compared to measures of generic musical training...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28522895/a-hearing-loss-prevention-outreach-program-for-farmers-and-motorsports-enthusiasts
#13
REVIEW
Melanie Buhr-Lawler
Many farmers and motorsports enthusiasts in rural areas attend tractor pulls, which are loud motorsport competitions using tractors and trucks with powerful, modified engines. The high noise levels experienced by farmers and motorsports fans in their recreational and occupational activities are not addressed by traditional hearing conservation programs. The University of Wisconsin-Madison audiology group has established an annual hearing loss prevention outreach project at the Dairyland Super National Truck and Tractor Pull in Tomah, Wisconsin...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522894/interventional-audiology-to-address-hearing-health-care-disparities-oyendo-bien-pilot-study
#14
REVIEW
Nicole Marrone, Maia Ingram, Maria Somoza, Daisey Sánchez Jacob, Adriana Sanchez, Stephanie Adamovich, Frances P Harris
Interventional audiology, specifically community-based outreach, can connect people with the hearing health care system. Community-based participatory research methods were applied in two phases of research to: (1) investigate the needs of families affected by hearing loss in a rural Arizona community on the U.S.-Mexico border; and (2) evaluate an outreach program on hearing health. The needs assessment included interviews with persons with hearing loss and focus groups with family members and the greater community...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522893/hearcare-hearing-and-communication-assistance-for-resident-engagement
#15
REVIEW
Catherine V Palmer, Reem Mulla, Elizabeth Dervin, Kathleen Costigan Coyan
Impaired hearing is related to poor health outcomes, including compromised cognitive function, in aging individuals. Hearing loss is the third most common chronic health condition after arthritis and heart disease in older adults and the fourth most detrimental condition related to quality of life in older adults. Only 18% of aging adults who have impactful hearing loss actually use custom-fit amplification. Therefore, the majority of aging individuals entering senior living facilities will have untreated hearing loss...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522892/enhancing-communication-in-adults-with-dementia-and-age-related-hearing-loss
#16
REVIEW
Sara K Mamo, Esther Oh, Frank R Lin
For many adults with dementia, age-related hearing loss is undiagnosed and/or untreated. Untreated hearing loss can exacerbate common dementia-related behavioral symptoms, such as depression, apathy, agitation. Despite the potential benefits to the individual and the family, pursuing and adopting hearing aids for persons with dementia presents with many challenges. As such, this group of vulnerable older adults is well suited for alternative approaches that adopt an interventional audiology framework. This article reviews alternative hearing care models that we have tested when working with older adults with cognitive impairments...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522891/the-role-of-audiology-in-an-outpatient-interdisciplinary-post-trauma-clinic
#17
REVIEW
Lori Zitelli, Catherine V Palmer
Patients in the process of recovering from severe bodily injury will encounter several barriers to effective treatment. When present, untreated hearing loss can create additional obstacles in a process that is already difficult. This article describes an outpatient post-trauma clinic associated with a tertiary care hospital trauma unit that consolidates rehabilitation resources 2 weeks after inpatient discharge to help these patients on their path to recovery. The role of audiology in the interdisciplinary clinic is described and data related to services are presented...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522890/the-effect-of-outpatient-interventional-audiology-on-inpatient-audiology-services
#18
REVIEW
Lori Zitelli, Catherine V Palmer
Although older adults are likely to experience some degree of hearing loss that if untreated will interfere with treatment for other disorders and result in less-than-optimal health care outcomes, health care providers do not have a reliable and cost-effective way to identify these individuals when admitted to a hospital for inpatient care. This article addresses the impact of untreated hearing loss on health care in a hospital setting and shares how the implementation of interventional audiology in an outpatient clinic has impacted the inpatient audiology services provided at a large tertiary care hospital...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522889/hearing-and-health-outcomes-recognizing-and-addressing-hearing-loss-in-hospitalized-older-adults
#19
REVIEW
Elaine Mormer, Janet Cipkala-Gaffin, Kelsi Bubb, Kelly Neal
As age increases, the prevalence of hearing loss significantly increases, reaching up to 89% of those 80 years and older. Hearing loss in older patients is often unrecognized and its consequences are often underappreciated. Hearing loss can interfere with the ability to exchange important health information and to participate in health care decision-making. Hearing loss during hospitalization increases the risk of misdiagnosis. There is a lack of empirical data regarding prevalence and recognition of hearing loss in hospitalized older adults...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522090/hearing-loss-mediates-executive-function-impairment-in-sleep-disordered-breathing
#20
Catherine M Hill, Romola S Bucks, Colin R Kennedy, Dawn Harrison, Annette Carroll, Nicolas Upton, Alexandra M Hogan
BACKGROUND: Sleep-disordered breathing (SDB) is often co-morbid with conductive hearing loss in early childhood due to a shared aetiology of adenotonsillar hypertrophy. Hearing loss is independently associated with impairment of executive function and behavioural difficulties. We hypothesised that these impairments in children with SDB may be mediated through hearing loss. METHODS: Fifty-eight children including 37 snorers awaiting adenotonsillectomy and 21 healthy non-snoring controls, aged 3-5 years, were assessed with pure tone audiometry, Strengths and Difficulties (SDQ), Behaviour Rating of Executive Function (BRIEF-P), and Childhood Middle Ear Disease and Hearing questionnaires...
June 2017: Sleep Medicine
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