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https://www.readbyqxmd.com/read/29351614/a-membrane-g-protein-coupled-estrogen-receptor-is-necessary-but-not-sufficient-for-sex-differences-in-zebra-finch-auditory-coding
#1
Amanda A Krentzel, Matheus Macedo-Lima, Maaya Z Ikeda, Luke Remage-Healey
Estradiol acts as a neuromodulator in brain regions important for cognition and sensory processing. Estradiol also shapes brain sex differences, but rarely have these concepts been considered simultaneously. In male and female songbirds, estradiol rapidly increases within the auditory forebrain during song exposure and enhances local auditory processing. We tested whether GPER1, a membrane bound estrogen receptor, is necessary and sufficient for neuroestrogen regulation of forebrain auditory processing in male and female zebra finches (Taeniopygia guttata)...
January 17, 2018: Endocrinology
https://www.readbyqxmd.com/read/29351276/static-length-changes-of-cochlear-outer-hair-cells-can-tune-low-frequency-hearing
#2
Nikola Ciganović, Rebecca L Warren, Batu Keçeli, Stefan Jacob, Anders Fridberger, Tobias Reichenbach
The cochlea not only transduces sound-induced vibration into neural spikes, it also amplifies weak sound to boost its detection. Actuators of this active process are sensory outer hair cells in the organ of Corti, whereas the inner hair cells transduce the resulting motion into electric signals that propagate via the auditory nerve to the brain. However, how the outer hair cells modulate the stimulus to the inner hair cells remains unclear. Here, we combine theoretical modeling and experimental measurements near the cochlear apex to study the way in which length changes of the outer hair cells deform the organ of Corti...
January 19, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29350260/modulation-rate-transfer-functions-from-four-species-of-stranded-odontocete-stenella-longirostris-feresa-attenuata-globicephala-melas-and-mesoplodon-densirostris
#3
Adam B Smith, Aude F Pacini, Paul E Nachtigall
Odontocete marine mammals explore the environment by rapidly producing echolocation signals and receiving the corresponding echoes, which likewise return at very rapid rates. Thus, it is important that the auditory system has a high temporal resolution to effectively process and extract relevant information from click echoes. This study used auditory evoked potential methods to investigate auditory temporal resolution of individuals from four different odontocete species, including a spinner dolphin (Stenella longirostris), pygmy killer whale (Feresa attenuata), long-finned pilot whale (Globicephala melas), and Blainville's beaked whale (Mesoplodon densirostris)...
January 19, 2018: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/29350061/the-adverse-effects-of-environmental-noise-exposure-on-oxidative-stress-and-cardiovascular-risk
#4
Thomas Münzel, Mette Sørensen, Frank P Schmidt, Erwin Schmidt, Sebastian Steven, Swenja Kröller-Schön, Andreas Daiber
Epidemiological studies have provided evidence that traffic noise exposure is linked to cardiovascular diseases such as arterial hypertension, myocardial infarction and stroke. Noise is a non-specific stressor that activates the autonomous nervous system and endocrine signaling. According to the noise reaction model introduced by Babisch and colleagues, chronic low levels of noise can cause so called non-auditory effects, such as disturbances of activity, sleep and communication, which can trigger a number of emotional responses, including annoyance and subsequent stress...
January 19, 2018: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29348292/morbid-jealousy-reactivated-by-mood-episodes
#5
Ruziana Masiran, Nik Shaliza Hussin
A middle-aged man who has been enduring financial constraint experienced a period of irritability, increased goal-directed activities and insomnia occurring along with extreme jealousy with his current wife. The episode was followed by depressed mood and non-prominent auditory hallucination. His previous history revealed a forensic psychiatry case of a murder he committed 20 years ago.
January 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29348192/differential-contributions-of-nucleus-accumbens-subregions-to-cue-guided-risk-reward-decision-making-and-implementation-of-conditional-rules
#6
Stan B Floresco, David R Montes, Maric M T Tse, Mieke van Holstein
The nucleus accumbens (NAc) is a key node within cortico-limbic circuitry for guiding action selection and cost/benefit decision making in situations involving reward uncertainty. Preclinical studies have typically assessed risk/reward decision making using assays where decisions are guided by internally-generated representations of choice-outcome contingencies. Yet, real-life decisions are often influenced by external stimuli that inform about likelihoods of obtaining rewards. How different subregions of the NAc mediate decision making in such situations is unclear...
January 18, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29347892/pilot-study-on-the-use-of-data-mining-to-identify-cochlear-implant-candidates
#7
Jedidiah J Grisel, Erin Schafer, Anne Lam, Terry Griffin
OBJECTIVES: The goal of this pilot study was to determine the clinical utility of data-mining software that screens for cochlear implant (CI) candidacy. METHODS: The Auditory Implant Initiative developed a software module that screens for CI candidates via integration with a software system (Noah 4) that serves as a depository for hearing test data. To identify candidates, patient audiograms from one practice were exported into the screening module. Candidates were tracked to determine if any eventually underwent implantation...
January 19, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29347860/alteration-of-auditory-function-in-type-2-diabetic-and-pre-diabetic-patients
#8
Jin Li, Yi Zhang, Xinxing Fu, Jingtao Bi, Yanhong Li, Bo Liu, Luo Zhang
BACKGROUND: The association between type 2 diabetes mellitus (T2DM) and hearing loss has not been fully investigated and there is little information on the effects of pre-diabetes on alterations in auditory function in Chinese subjects. METHODS: The study recruited 51 patients with T2DM, 55 patients with pre-diabetes and 43 control subjects. Auditory function was assessed by pure tone audiometry (PTA) tests and distortion product of otoacoustic emissions (DPOAEs)...
January 18, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29346755/connecting-neural-codes-with-behavior-in-the-auditory-system-of-drosophila
#9
Jan Clemens, Cyrille C Girardin, Philip Coen, Xiao-Juan Guan, Barry J Dickson, Mala Murthy
No abstract text is available yet for this article.
January 17, 2018: Neuron
https://www.readbyqxmd.com/read/29346017/the-role-of-posterior-parietal-cortex-in-beat-based-timing-perception-a-continuous-theta-burst-stimulation-study
#10
Jessica M Ross, John R Iversen, Ramesh Balasubramaniam
There is a growing interest in how the brain's motor systems contribute to the perception of musical rhythms. The Action Simulation for Auditory Prediction hypothesis proposes that the dorsal auditory stream is involved in bidirectional interchange between auditory perception and beat-based prediction in motor planning structures via parietal cortex [Patel, A. D., & Iversen, J. R. The evolutionary neuroscience of musical beat perception: The Action Simulation for Auditory Prediction (ASAP) hypothesis. Frontiers in Systems Neuroscience, 8, 57, 2014]...
January 18, 2018: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29345531/how-tailoring-the-mode-of-information-presentation-influences-younger-and-older-adults-satisfaction-with-health-websites
#11
Minh Hao Nguyen, Ellen M A Smets, Nadine Bol, Eugène F Loos, Julia C M Van Weert
Although older adults are increasingly using online health information, many websites are not senior-friendly, which might lead to user-problems and dissatisfaction among older people. It has been suggested that websites targeted at older adults should take into account age-related abilities and limitations, for example by providing the opportunity to adjust the modality (i.e., "mode") of information presentation based on visual and auditory capabilities. This study investigates the effects of a mode-tailored website, allowing users to self-tailor the mode of information presentation, on younger and older adults' satisfaction with health websites...
January 18, 2018: Journal of Health Communication
https://www.readbyqxmd.com/read/29345019/a-vascular-mechanism-to-explain-thermally-mediated-variations-in-deep-body-cooling-rates-during-the-immersion-of-profoundly-hyperthermic-individuals
#12
Joanne N Caldwell, Anne M J van den Heuvel, Pete Kerry, Mitchell J Clark, Gregory E Peoples, Nigel A S Taylor
Physiologically trivial time differences for cooling the intrathoracic viscera of hyperthermic individuals have been reported between cold- and temperate-water immersion treatments. One explanation for that observation is reduced convective heat delivery to the skin during cold immersion, and this experiment was designed to test both the validity of that observation, and its underlying hypothesis. Eight healthy males participated in four head-out, water immersions: two when normothermic, and two following exercise-induced, moderate-profound hyperthermia...
January 18, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29344647/autophagy-regulates-the-degeneration-of-the-auditory-cortex-through-the-ampk-mtor-ulk1-signaling-pathway
#13
Jie Yuan, Xueyan Zhao, Yujuan Hu, Haiying Sun, Guoqing Gong, Xiang Huang, Xubo Chen, Mingyu Xia, Chen Sun, Qilin Huang, Yu Sun, Wen Kong, Weijia Kong
Presbycusis is the most common sensory impairment associated with aging; however, the underlying molecular mechanism remains unclear. Autophagy has been demonstrated to serve a key role in diverse diseases; however, no studies have examined its function in central presbycusis. The aim of the present study was to investigate the changes of autophagy in the physiological processes of the auditory cortex and its role in the degeneration of the auditory cortex, as well as the related mechanisms using naturally aging rats and a D‑galactose (D‑gal)‑induced mimetic rat model of aging...
January 17, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29343859/rate-after-effects-fail-to-transfer-cross-modally-evidence-for-distributed-sensory-timing-mechanisms
#14
Aysha Motala, James Heron, Paul V McGraw, Neil W Roach, David Whitaker
Accurate time perception is critical for a number of human behaviours, such as understanding speech and the appreciation of music. However, it remains unresolved whether sensory time perception is mediated by a central timing component regulating all senses, or by a set of distributed mechanisms, each dedicated to a single sensory modality and operating in a largely independent manner. To address this issue, we conducted a range of unimodal and cross-modal rate adaptation experiments, in order to establish the degree of specificity of classical after-effects of sensory adaptation...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343839/musical-auditory-stimulus-acutely-influences-heart-rate-dynamic-responses-to-medication-in-subjects-with-well-controlled-hypertension
#15
Eli Carlos Martiniano, Milana Drumond Ramos Santana, Érico Luiz Damasceno Barros, Maria do Socorro da Silva, David Matthew Garner, Luiz Carlos de Abreu, Vitor E Valenti
Music can improve the efficiency of medical treatment when correctly associated with drug action, reducing risk factors involving deteriorating cardiac function. We evaluated the effect of musical auditory stimulus associated with anti-hypertensive medication on heart rate (HR) autonomic control in hypertensive subjects. We evaluated 37 well-controlled hypertensive patients designated for anti-hypertensive medication. Heart rate variability (HRV) was calculated from the HR monitor recordings of two different, randomly sorted protocols (control and music) on two separate days...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343771/magnetoencephalographic-correlates-of-perceptual-state-during-auditory-bistability
#16
Robert D Sanders, Joel S Winston, Gareth R Barnes, Geraint Rees
Bistability occurs when two alternative percepts can be derived from the same physical stimulus. To identify the neural correlates of specific subjective experiences we used a bistable auditory stimulus and determined whether the two perceptual states could be distinguished electrophysiologically. Fourteen participants underwent magnetoencephalography while reporting their perceptual experience while listening to a continuous bistable stream of auditory tones. Participants reported bistability with a similar overall proportion of the two alternative percepts (52% vs 48%)...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343736/establishing-a-mental-lexicon-with-cochlear-implants-an-erp-study-with-young-children
#17
Niki K Vavatzanidis, Dirk Mürbe, Angela D Friederici, Anja Hahne
In the present study we explore the implications of acquiring language when relying mainly or exclusively on input from a cochlear implant (CI), a device providing auditory input to otherwise deaf individuals. We focus on the time course of semantic learning in children within the second year of implant use; a period that equals the auditory age of normal hearing children during which vocabulary emerges and extends dramatically. 32 young bilaterally implanted children saw pictures paired with either matching or non-matching auditory words...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343638/commissural-neurons-transgress-the-cns-pns-boundary-in-absence-of-ventricular-zone-derived-netrin-1
#18
Juan Antonio Moreno-Bravo, Sergi Roig Puiggros, Heike Blockus, Chloé Dominici, Pavol Zelina, Patrick Mehlen, Alain Chédotal
During the development of the central nervous system (CNS), only motor axons project into peripheral nerves. Little is known about the cellular and molecular mechanisms that control the development of a boundary at the CNS surface and prevent CNS neuron emigration from the neural tube. It has previously been shown that a subset of spinal cord commissural axons abnormally invades sensory nerves in Ntn1 hypomorphic embryos and Dcc knockouts. However, whether netrin 1 also plays a similar role in the brain is unknown...
January 17, 2018: Development
https://www.readbyqxmd.com/read/29343467/hearing-impairment-in-patients-with-myotonic-dystrophy-type-2
#19
Judith van Vliet, Alide A Tieleman, Baziel G M van Engelen, Guillaume Bassez, Laurent Servais, Anthony Béhin, Tanya Stojkovic, Jan Meulstee, Joost A M Engel, George Lamas, Bruno Eymard, Wim I M Verhagen, Elisabeth Mamelle
OBJECTIVE: To systematically assess auditory characteristics of a large cohort of patients with genetically confirmed myotonic dystrophy type 2 (DM2). METHODS: Patients with DM2 were included prospectively in an international cross-sectional study. A structured interview about hearing symptoms was held. Thereafter, standardized otologic examination, pure tone audiometry (PTA; 0.25, 0.5, 1, 2, 4, and 8 kHz), speech audiometry, tympanometry, acoustic middle ear muscle reflexes, and brainstem auditory evoked potentials (BAEP) were performed...
January 17, 2018: Neurology
https://www.readbyqxmd.com/read/29343230/the-sybil-aa-real-time-fmri-neurofeedback-study-protocol-of-a-single-blind-randomized-controlled-trial-in-alcohol-use-disorder
#20
Martin Fungisai Gerchen, Martina Kirsch, Nathalie Bahs, Patrick Halli, Sarah Gerhardt, Axel Schäfer, Wolfgang H Sommer, Falk Kiefer, Peter Kirsch
BACKGROUND: Alcohol Use Disorder is a highly prevalent mental disorder which puts a severe burden on individuals, families, and society. The treatment of Alcohol Use Disorder is challenging and novel and innovative treatment approaches are needed to expand treatment options. A promising neuroscience-based intervention method that allows targeting cortical as well as subcortical brain processes is real-time functional magnetic resonance imaging neurofeedback. However, the efficacy of this technique as an add-on treatment of Alcohol Use Disorder in a clinical setting is hitherto unclear and will be assessed in the Systems Biology of Alcohol Addiction (SyBil-AA) neurofeedback study...
January 17, 2018: BMC Psychiatry
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