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https://www.readbyqxmd.com/read/28934723/neural-mechanisms-underlying-the-disruption-of-male-courtship-behavior-by-adult-exposure-to-di-2-ethylhexyl-phthalate-in-mice
#1
Carlos Dombret, Daphné Capela, Kevin Poissenot, Caroline Parmentier, Emma Bergsten, Cédric Pionneau, Solenne Chardonnet, Hélène Hardin-Pouzet, Valérie Grange-Messent, Matthieu Keller, Isabelle Franceschini, Sakina Mhaouty-Kodja
BACKGROUND: Courtship behavior plays a critical role in attracting females and reproduction success. However, the effects of exposure to a ubiquitous contaminant di(2-ethylhexyl) phthalate (DEHP) on these behaviors and, in particular, on courtship vocalizations have not been examined. OBJECTIVE: The effects of adult exposure to DEHP on courtship and mating behaviors and gonadotropic axis and neural mechanisms involved in DEHP-induced effects were analyzed in male mice...
September 1, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934663/using-a-fluorescence-quenching-method-to-detect-dna-adsorption-onto-single-walled-carbon-nanotube-surfaces
#2
Kazuo Umemura, Shizuma Sato, Gilbert Bustamante, Jing Yong Ye
Surface modification of single-walled carbon nanotubes (SWNTs) with DNA molecules has attracted much attention in recent years to increase SWNT solubility and make various SWNT-based nanobiodevices. Therefore, there is a critical need to quantify the interaction between DNA molecules and SWNT surfaces, particularly the intermediate structures during DNA adsorption. In this study, we demonstrate the ability to detect the adsorption of DNA oligomers on SWNT surfaces by fluorescence spectroscopy. Fluorescein-labelled, 30mer, thymine oligonucleotides (F-T30) were employed as a fluorescent probe to study the interaction of DNA with SWNTs...
September 12, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28934653/mixed-sulfate-reducing-bacteria-enriched-microbial-fuel-cells-for-the-treatment-of-wastewater-containing-copper
#3
Waheed Miran, Jiseon Jang, Mohsin Nawaz, Asif Shahzad, Sang Eun Jeong, Che Ok Jeon, Dae Sung Lee
Microbial fuel cells (MFCs) have been widely investigated for organic-based waste/substrate conversion to electricity. However, toxic compounds such as heavy metals are ubiquitous in organic waste and wastewater. In this work, a sulfate reducing bacteria (SRB)-enriched anode is used to study the impact of Cu(2+) on MFC performance. This study demonstrates that MFC performance is slightly enhanced at concentrations of up to 20 mg/L of Cu(2+), owing to the stimulating effect of metals on biological reactions...
September 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934416/transporter-engineering-in-biomass-utilization-by-yeast
#4
Kiyotaka Y Hara, Jyumpei Kobayashi, Ryosuke Yamada, Daisuke Sasaki, Yuki Kuriya, Yoko Hirono-Hara, Jun Ishii, Michihiro Araki, Akihiko Kondo
Biomass resources are attractive carbon sources for bioproduction because of their sustainability. Many studies have been performed using biomass resources to produce sugars as carbon sources for cell factories. Expression of biomass hydrolyzing enzymes in cell factories is an important approach for constructing biomass-utilizing bioprocesses because external addition of these enzymes is expensive. In particular, yeasts have been extensively engineered to be cell factories that directly utilize biomass because of their manageable responses to many genetic engineering tools, such as gene expression, deletion and editing...
November 1, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/28934372/antibacterial-effects-of-the-artificial-surface-of-nanoimprinted-moth-eye-film
#5
Kiyoshi Minoura, Miho Yamada, Takashi Mizoguchi, Toshihiro Kaneko, Kyoko Nishiyama, Mari Ozminskyj, Tetsuo Koshizuka, Ikuo Wada, Tatsuo Suzutani
The antibacterial effect of a nanostructured film, known as "moth-eye film," was investigated. The moth-eye film has artificially formed nano-pillars, consisting of hydrophilic resin with urethane acrylate and polyethylene glycol (PEG) derivatives, all over its surface that replicates a moth's eye. Experiments were performed to compare the moth-eye film with a flat-surfaced film produced from the same materials. The JIS Z2801 film-covering method revealed that the two films produced a decrease in Staphylococcus aureus and Esherichia coli titers of over 5 and 3 logs, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28934363/sex-related-differences-in-the-risk-factors-for-in-hospital-mortality-and-outcomes-of-ischemic-stroke-patients-in-rural-areas-of-taiwan
#6
Cheung-Ter Ong, Yi-Sin Wong, Sheng-Feng Sung, Chi-Shun Wu, Yung-Chu Hsu, Yu-Hsiang Su, Ling-Chien Hung
BACKGROUND AND PURPOSE: Sex-related differences in the clinical presentation and outcomes of stroke patients are issues that have attracted increased interest from the scientific community. The present study aimed to investigate sex-related differences in the risk factors for in-hospital mortality and outcome in ischemic stroke patients. METHODS: A total of 4278 acute ischemic stroke patients admitted to a stroke unit between January 1, 2007 and December 31, 2014 were included in the study...
2017: PloS One
https://www.readbyqxmd.com/read/28934352/global-reaction-to-the-recent-outbreaks-of-zika-virus-insights-from-a-big-data-analysis
#7
Nicola Luigi Bragazzi, Cristiano Alicino, Cecilia Trucchi, Chiara Paganino, Ilaria Barberis, Mariano Martini, Laura Sticchi, Eugen Trinka, Francesco Brigo, Filippo Ansaldi, Giancarlo Icardi, Andrea Orsi
OBJECTIVE: The recent spreading of Zika virus represents an emerging global health threat. As such, it is attracting public interest worldwide, generating a great amount of related Internet searches and social media interactions. The aim of this research was to understand Zika-related digital behavior throughout the epidemic spreading and to assess its consistence with real-world epidemiological data, using a behavioral informatics and analytics approach. METHODS: In this study, the global web-interest and reaction to the recently occurred outbreaks of the Zika Virus were analyzed in terms of tweets and Google Trends (GT), Google News, YouTube, and Wikipedia search queries...
2017: PloS One
https://www.readbyqxmd.com/read/28934169/function-oriented-molecular-design-dendrimers-as-novel-antimicrobials
#8
REVIEW
Sandra García-Gallego, Gianluigi Franci, Annarita Falanga, Rafael Gómez, Veronica Folliero, Stefania Galdiero, Francisco Javier de la Mata, Massimiliano Galdiero
In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds...
September 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28934154/why-human-papillomaviruses-activate-the-dna-damage-response-ddr-and-how-cellular-and-viral-replication-persists-in-the-presence-of-ddr-signaling
#9
REVIEW
Molly L Bristol, Dipon Das, Iain M Morgan
Human papillomaviruses (HPV) require the activation of the DNA damage response (DDR) in order to undergo a successful life cycle. This activation presents a challenge for the virus and the infected cell: how does viral and host replication proceed in the presence of a DDR that ordinarily arrests replication; and how do HPV16 infected cells retain the ability to proliferate in the presence of a DDR that ordinarily arrests the cell cycle? This raises a further question: why do HPV activate the DDR? The answers to these questions are only partially understood; a full understanding could identify novel therapeutic strategies to target HPV cancers...
September 21, 2017: Viruses
https://www.readbyqxmd.com/read/28934149/oncolytic-reovirus-infection-is-facilitated-by-the-autophagic-machinery
#10
Vera Kemp, Iris J C Dautzenberg, Ronald W Limpens, Diana J M van den Wollenberg, Rob C Hoeben
Mammalian reovirus is a double-stranded RNA virus that selectively infects and lyses transformed cells, making it an attractive oncolytic agent. Despite clinical evidence for anti-tumor activity, its efficacy as a stand-alone therapy remains to be improved. The success of future trials can be greatly influenced by the identification and the regulation of the cellular pathways that are important for reovirus replication and oncolysis. Here, we demonstrate that reovirus induces autophagy in several cell lines, evident from the formation of Atg5-Atg12 complexes, microtubule-associated protein 1 light chain 3 (LC3) lipidation, p62 degradation, the appearance of acidic vesicular organelles, and LC3 puncta...
September 21, 2017: Viruses
https://www.readbyqxmd.com/read/28934132/surface-modification-of-polymer-substrates-for-biomedical-applications
#11
REVIEW
Oldřich Neděla, Petr Slepička, Václav Švorčík
While polymers are widely utilized materials in the biomedical industry, they are rarely used in an unmodified state. Some kind of a surface treatment is often necessary to achieve properties suitable for specific applications. There are multiple methods of surface treatment, each with their own pros and cons, such as plasma and laser treatment, UV lamp modification, etching, grafting, metallization, ion sputtering and others. An appropriate treatment can change the physico-chemical properties of the surface of a polymer in a way that makes it attractive for a variety of biological compounds, or, on the contrary, makes the polymer exhibit antibacterial or cytotoxic properties, thus making the polymer usable in a variety of biomedical applications...
September 21, 2017: Materials
https://www.readbyqxmd.com/read/28933959/what-makes-a-dog-adoptable-an-eye-tracking-investigation
#12
Sara Isgate, Justin J Couchman
Humans readily attribute personality and behavioral traits to dogs, and these attributions influence decisions about adoption. This study focused on how these attributions could be influenced by breed and pose by using pictures of four breeds (Doberman Pinscher, Golden Retriever, pit bull, and Rottweiler) in 4 poses (dog sitting alone, sitting with a human, standing alone, and walking on a leash with a human). Participants rated each picture on friendliness, aggressiveness, and adoptability. Eye-tracking technology identified which specific features were represented in each picture to determine whether they had any effect on the judgments...
September 21, 2017: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28933953/differential-programming-needs-of-college-students-preferring-web-based-versus-in-person-physical-activity-programs
#13
Stephanie P Goldstein, Evan M Forman, Meghan L Butryn, James D Herbert
College students report several barriers to exercise, highlighting a need for university-based programs that address these challenges. In contrast to in-person interventions, several web-based programs have been developed to enhance program engagement by increasing ease of access and lowering the necessary level of commitment to participate. Unfortunately, web-based programs continue to struggle with engagement and less-than-ideal outcomes. One explanation for this discrepancy is that different intervention modalities may attract students with distinctive activity patterns, motivators, barriers, and program needs...
September 21, 2017: Health Communication
https://www.readbyqxmd.com/read/28933894/category-structure-determines-the-relative-attractiveness-of-global-versus-local-averages
#14
Tobias Vogel, Evan W Carr, Tyler Davis, Piotr Winkielman
Stimuli that capture the central tendency of presented exemplars are often preferred-a phenomenon also known as the classic beauty-in-averageness effect. However, recent studies have shown that this effect can reverse under certain conditions. We propose that a key variable for such ugliness-in-averageness effects is the category structure of the presented exemplars. When exemplars cluster into multiple subcategories, the global average should no longer reflect the underlying stimulus distributions, and will thereby become unattractive...
September 21, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28933875/-sex-differences-in-left-handedness-a-meta-analysis-of-144-studies-correction-to-papadatou-pastou-et-al-2008
#15
(no author information available yet)
Reports an error in "Sex differences in left-handedness: A meta-analysis of 144 studies" by Marietta Papadatou-Pastou, Maryanne Martin, Marcus R. Munafò and Gregory V. Jones (Psychological Bulletin, 2008[Sep], Vol 134[5], 677-699). In the article the statistical evidence is weaker than reported for the moderating effect of writing hand compared to all the other instruments (reported finding: Q(1) = 8.36, p = .02; corrected finding: Q(1) = 3.17, p = .075). While the statistical evidence is thus somewhat weaker on this particular point, the broad conclusions of the article remain unchanged...
October 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28933857/giant-enhancement-of-cathodoluminescence-of-monolayer-transitional-metal-dichalcogenides-semiconductors
#16
Shoujun Zheng, Jinkyu So, Fucai Liu, Zheng Liu, Nikolay I Zheludev, Hong Jin Fan
Monolayer two-dimensional transitional metal dichalcogenides, such as MoS2, WS2 and WSe2, are direct band gap semiconductors with large exciton binding energy. They attract growing attentions for opto-electronic applications including solar cells, photo-detectors, light-emitting diodes and photo-transistors, capacitive energy storage, photodynamic cancer therapy and sensing on flexible platforms. While light-induced luminescence has been widely studied, luminescence induced by injection of free electrons could promise another important applications of these new materials...
September 21, 2017: Nano Letters
https://www.readbyqxmd.com/read/28933752/graphene-field-effect-transistors-for-biomedical-applications-current-status-and-future-prospects
#17
REVIEW
Rhiannan Forsyth, Anitha Devadoss, Owen J Guy
Since the discovery of the two-dimensional (2D) carbon material, graphene, just over a decade ago, the development of graphene-based field effect transistors (G-FETs) has become a widely researched area, particularly for use in point-of-care biomedical applications. G-FETs are particularly attractive as next generation bioelectronics due to their mass-scalability and low cost of the technology's manufacture. Furthermore, G-FETs offer the potential to complete label-free, rapid, and highly sensitive analysis coupled with a high sample throughput...
July 26, 2017: Diagnostics
https://www.readbyqxmd.com/read/28933528/inert-layered-silicate-improves-the-electrochemical-responses-of-a-metal-complex-polymer
#18
Miharu Eguchi, Masako Momotake, Fumie Inoue, Takayoshi Oshima, Kazuhiko Maeda, Masayoshi Higuchi
A chemically inert, insulating layered silicate (saponite; SP) and an iron(II)-based metallo-supramolecular complex polymer (polyFe) were combined via electrostatic attraction to improve the electrochromic properties of polyFe. Structural characterization indicated that polyFe was intercalated into the SP nanosheets. Interestingly, the redox potential of polyFe was lowered by combining it with SP, and the current was measurable despite the insulating nature of SP. X-ray photoelectron spectroscopy showed that the decrease of the redox potential observed in the SP-polyFe hybrid was caused by electrostatic neutralization of the Fe cation in polyFe by the negative charge on SP...
September 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28933500/significant-improvement-of-near-uv-electroluminescence-from-zno-quantum-dot-leds-via-coupling-with-carbon-nanodot-surface-plasmons
#19
Cen Zhang, Feifei Zhu, Haiyang Xu, Weizhen Liu, Liu Yang, Zhongqiang Wang, Jiangang Ma, Zhenhui Kang, Yichun Liu
Short-wavelength LEDs, a hot research topic in modern optoelectronics, have attracted tremendous attention in recent years because of their great application potential in both civil and military domains. Compared to conventional metallic surface-plasmons (SPs), carbon nanodot (CD) SPs with less optical loss and low cost, broader SP resonant frequency and good biocompatibility are expected to provide more prominent luminescence enhancement for light emitters. Herein, SP-enhanced near-UV emission quantum dot LEDs (Q-LED) were fabricated via introducing CDs into p-GaN/Al2O3/ZnO Q-LEDs by optimizing the molar ratio of ZnO quantum dots to CDs and a significant enhancement (∼20-fold) of the near-UV electroluminescence (EL) intensity from the ZnO-based Q-LEDs was achieved...
September 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28933477/a-cobalt-ii-heteroarylalkenolate-precursor-for-homogeneous-co3o4-coatings-by-atomic-layer-deposition
#20
Mehtap Büyükyazi, Thomas Fischer, Penmgei Yu, Mariona Coll, Sanjay Mathur
We present a new and efficient cobalt precursor, Co(II)(DMOCHCOCF3)2, to prepare Co3O4 thin films and conformal coatings. In the synthesis of this Co complex, heteroaryl moieties and CF3-groups were combined leading to the precursor with high thermal stability and volatility. The suitability of this precursor for ALD deposition was tested on flat silicon substrates and TiO2/C nanofibers upon process optimization. Deposition at 200 °C results in homogeneous and smooth Co3O4 thin films with a growth rate of 0...
September 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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