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https://www.readbyqxmd.com/read/29148903/an-onyx-tunnel-reconstructive-transvenous-balloon-assisted-onyx-embolization-for-dural-arteriovenous-fistula-of-the-transverse-sigmoid-sinus
#1
Mena G Kerolus, Joonho Chung, Stephen A Munich, Yoshikazu Matsuda, Hideo Okada, Demetrius K Lopes
Transvenous embolization is an effective method for treating dural arteriovenous fistulas (DAVFs) of the transverse-sigmoid sinus (TSS). However, in cases of complicated DAVFs, it is difficult to preserve the patency of the dural sinus. The authors describe the technical details of a new reconstructive technique using transvenous balloon-assisted Onyx embolization as another treatment option in a patient with an extensive and complex DAVF of the left TSS. A microcatheter and compliant balloon catheter were navigated into the left internal jugular vein and placed at the distal end of the DAVF in the transverse sinus...
November 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29130853/endovascular-treatment-of-12-cases-of-renal-arteriovenous-malformations-the-experience-of-1-center-and-an-overview-of-the-literature
#2
Zhen-Yu Jia, Chun-Gao Zhou, Jin-Guo Xia, Lin-Bo Zhao, Wen Zhang, Sheng Liu, Hai-Bin Shi
OBJECTIVES: Congenital renal arteriovenous malformations (rAVMs) represent rare vascular diseases. The heterogeneous vascular architecture of each rAVM determines the endovascular treatment techniques employed. We reported our experience with the endovascular treatment of a series of rAVMs. MATERIALS: This retrospective study consisted of 12 patients with 12 rAVMs who underwent renal arterial embolization (RAE) in our hospital. Embolic materials, including particles, liquid embolic agents (n-butyl 2-cyanoacrylate, Onyx, and ethanol), and coils, were selectively used based on the decisions of interventional radiologists...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29125026/delayed-and-incomplete-treatment-may-result-in-dural-fistula-development-in-children-with-vein-of-galen-malformation
#3
Dan Meila, Cynthia Schmidt, Katharina Melber, Dominik Grieb, Cornelius Jacobs, Collin Jacobs, Heinrich Lanfermann, Friedhelm Brassel
The association of dural arteriovenous fistulas (DAVF) in children with Vein of Galen malformation (VGM) has recently been reported for the first time. In a larger series of cases treated with transarterial NBCA embolization, 30% had DAVF. We wanted to analyze the development of DAVF in our cohort of children with VGM and to evaluate whether their occurrence depends on different treatment timing and embolic materials. We analyzed 43 VGM cases treated with a combined transarterial and transvenous approach between 2003 and 2016...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29123452/mechanical-extraction-of-a-refluxed-onyx-piece-from-the-sigmoid-sinus-using-a-solitaire-ab-stent-for-treating-a-dural-arteriovenous-fistula-technical-report
#4
Erdem Cayli, Sukru Oguz, Hasan Dinc
No abstract text is available yet for this article.
October 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29119877/direct-puncture-onyx-embolization-of-a-large-calvarial-metastasis-with-intracranial-extension-case-report
#5
Minerva H Zhou, Gavin P Dunn, Joshua W Osbun, DeWitte T Cross, Christopher J Moran, Ralph G Dacey, Akash P Kansagra
We report a case of renal cell carcinoma (RCC) metastasis to the calvarium and describe a strategy for percutaneous embolization of hypervascular calvarial tumors with intracranial extension. An elderly patient with history of RCC presented with left-sided weakness. Imaging studies showed a large right frontoparietal calvarial mass with intra- and extracranial extension. The tumor was devascularized by direct puncture tumor embolization using Onyx 18, allowing subsequent operative resection without significant blood loss or the need for flap reconstruction of the scalp...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29114088/unruptured-brain-arteriovenous-malformations-primary-onyx-embolization-in-aruba-a-randomized-trial-of-unruptured-brain-arteriovenous-malformations-eligible-patients
#6
Uri Singfer, Dimitri Hemelsoet, Peter Vanlangenhove, Frederic Martens, Luc Verbeke, Dirk Van Roost, Luc Defreyne
BACKGROUND AND PURPOSE: In light of evidence from ARUBA (A Randomized Trial of Unruptured Brain Arteriovenous Malformations), neurovascular specialists had to reconsider deliberate treatment of unruptured brain arteriovenous malformations (uBAVMs). Our objective was to determine the outcomes of uBAVM treated with primary embolization using ethylene vinyl alcohol (ONYX). METHODS: Patients with uBAVM who met the inclusion criteria of ARUBA and were treated with primary Onyx embolization were assigned to this retrospective study...
November 7, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29107898/negative-effects-of-microplastic-exposure-on-growth-and-development-of-crepidula-onyx
#7
Hau Kwan Abby Lo, Kit Yu Karen Chan
Microplastics exposure could be detrimental to marine organisms especially under high concentrations. However, few studies have considered the multiphasic nature of marine invertebrates' life history and investigated the impact of experiencing microplastics during early development on post-metamorphic stages (legacy effect). Many planktonic larvae can feed selectively and it is unclear whether such selectivity could modulate the impact of algal food-sized microplastic. In this two-stage experiment, veligers of Crepidula onyx were first exposed to additions of algae-sized micro-polystyrene (micro-PS) beads at different concentrations, including ones that were comparable their algal diet...
November 3, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29107165/transarterial-onyx-%C3%A2-embolization-of-bilateral-transverse-sigmoid-dural-arteriovenous-malformation-with-transvenous-balloon-assist-initial-us-experience-with-the-copernic-rc-venous-remodeling-balloon
#8
Abdulrahman Alturki, Alejandro Enriquez-Marulanda, Philip Schmalz, Christopher S Ogilvy, Ajith J Thomas
No abstract text is available yet for this article.
October 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29084067/a-randomized-control-trial-of-cardiopulmonary-feedback-devices-and-their-impact-on-infant-chest-compression-quality-a-simulation-study
#9
Andrea L Austin, Carmen N Spalding, Katrina N Landa, Brian R Myer, Cure Donald, Jason E Smith, Gerald Platt, Heather C King
OBJECTIVES: In effort to improve chest compression quality among health care providers, numerous feedback devices have been developed. Few studies, however, have focused on the use of cardiopulmonary resuscitation feedback devices for infants and children. This study evaluated the quality of chest compressions with standard team-leader coaching, a metronome (MetroTimer by ONYX Apps), and visual feedback (SkillGuide Cardiopulmonary Feedback Device) during simulated infant cardiopulmonary resuscitation...
October 27, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29056193/laser-assisted-transgraft-embolization-a%C3%A2-technique-for-the-treatment-of-type-ii-endoleaks
#10
Mark W Mewissen, M Fuad Jan, David Kuten, Zvonimir Krajcer
A transgraft embolization (TGE) technique was performed in a patient to treat a type II endoleak. Using a transfemoral arterial approach, the endograft was punctured using a coronary laser catheter aimed toward the type II endoleak nidus, which was treated with Onyx (Medtronic, Minneapolis, Minnesota). TGE resulted in successful embolization, as demonstrated on 1-year follow-up CT angiography, which showed complete elimination of the type II endoleak and shrinkage of the aneurysmal sac. TGE is an alternative to transarterial embolization, translumbar embolization, and transcaval embolization...
November 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29054956/indirect-carotid-cavernous-fistula-mimicking-ocular-myasthenia
#11
Lakshmi Leishangthem, Sudhakar Reddy Satti
71-year-old woman with progressive left-sided, monocular diplopia and ptosis. Her symptoms mimicked ocular myasthenia, but she had an indirect carotid cavernous fistula (CCF). She was diagnosed with monocular myasthenia gravis (negative acetylcholinesterase antibody) after a positive ice test and started on Mestinon and underwent a thymectomy complicated by a brachial plexus injury. Months later, she developed left-sided proptosis and ocular bruit. She was urgently referred to neuro-interventional surgery and was diagnosed with an indirect high-flow left CCF, which was treated with Onyx liquid and platinum coil embolisation...
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29026675/advantages-of-using-a-detachable-tip-microcatheter-and-liquid-embolic-agents-in-the-preoperative-embolization-of-a-recurrent-cerebellar-hemangioblastoma-a-case-report
#12
Nicolas Yanez, Luisa K Cifuentes, Marcela Mejia, Juan N Useche
BACKGROUND: The preferred treatment for intracranial hemangioblastomas is surgical resection with or without preoperative embolization, however, embolization remains controversial due to risks such as distal tip entrapment, vascular injury during navigation, and embolic agent migration. CASE DESCRIPTION: A 54-year-old woman was admitted for surgical resection and preoperative embolization of a cerebellar hemangioblastoma. Although experience using Onyx with detachable and nondetachable tip microcatheters has been well reported in a variety of clinical circumstances, we describe the first case of a presurgical embolization of an intra-axial tumor using a second-generation detachable-tip microcatheter and a nonadhesive liquid embolic agent...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28988940/dual-lumen-balloon-to-increase-onyx-venous-penetration-in-the-treatment-of-spinal-dural-arteriovenous-fistulas
#13
Felipe Padovani Trivelato, Marco Túlio Salles Rezende, Alexandre Cordeiro Ulhoa, Guilherme Seizem Nakiri, Daniel Giansante Abud
PURPOSE: Spinal dural arteriovenous fistulas (sDAVF) are the most common spinal vascular lesions. The arterialization of the recipient vein results in venous hypertension and chronic ischemia. Intravascular injection of acrylic glue in order to occlude the draining vein is the principle of endovascular treatment, but a significant portion of embolization procedures do not succeed. We present our initial experience of endovascular balloon augmented embolization of sDAVF using a dual-lumen balloon...
October 5, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28975855/treatment-of-cranial-dural-arteriovenous-fistulas-with-exclusive-cortical-venous-drainage-a-single-center-cohort-of-35-patients
#14
H G Kortman, G Bloemsma, I Boukrab, J P Peluso, M Sluzewski, B van der Pol, G N Beute, C B Majoie, W J van Rooij
Background and purpose Dural arteriovenous fistulas (DAVFs) with cortical venous drainage often present with hemorrhage or neurological deficits and prompt treatment is indicated. Disconnection of the draining vein is considered curative. We present the multimodality treatment results of 35 patients with cranial DAVFs with exclusive cortical venous drainage. Materials and methods Between January 2010 and January 2017, 35 consecutive patients with cranial dural fistulas with exclusive cortical venous drainage were treated...
December 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28963167/embolization-of-a-cavernous-carotid-fistula-through-the-vein-of-labb%C3%A3-a-new-alternative-transvenous-access-route
#15
Angelos Aristeidis Konstas, Alice Song, Julia Song, Aristomenis Thanos, Ian B Ross
Endovascular treatment of carotid cavernous fistulas (CCFs) via a transvenous approach is standard, but in rare cases this approach is challenging due to absence or thrombosis of the commonly used venous routes. A 61-year-old woman presented with a symptomatic CCF with all but one of the venous access routes to the CCF thrombosed, leaving an engorged superficial middle cerebral vein (SMCV) as the only venous outflow from the cavernous sinus. Access to the CCF was made possible after careful navigation of the sigmoid sinus, the vein of Labbé and the SMCV, bypassing the need for surgical access to the SMCV or for a direct transorbital puncture...
September 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28940882/safety-and-efficacy-of-the-next-generation-resolute-onyx-zotarolimus-eluting-stent-primary-outcome-of-the-resolute-onyx-core-trial
#16
Matthew J Price, Richard A Shlofmitz, Douglas J Spriggs, Thomas A Haldis, Paul Myers, Alexandra Popma Almonacid, Akiko Maehara, Michelle Dauler, Yun Peng, Roxana Mehran
OBJECTIVES: To assess the safety and efficacy of the novel Resolute (R-) Onyx drug-eluting stent (DES). BACKGROUND: The R-Onyx DES consists of a composite wire with an outer shell of cobalt chromium alloy and a platinum-iridium inner core to enhance radiopacity, with thinner, swaged struts and modified stent geometry compared with the predicate Resolute DES, resulting in a slightly lower total drug load in most sizes. METHODS: This was a prospective, single-arm non-inferiority trial compared with a historical control...
September 23, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28935906/resilience-of-the-larval-slipper-limpet-crepidula-onyx-to-direct-and-indirect-diet-effects-of-ocean-acidification
#17
Elizaldy A Maboloc, Kit Yu Karen Chan
Ocean acidification (OA) is known to directly impact larval physiology and development of many marine organisms. OA also affects the nutritional quality and palatability of algae, which are principal food sources for many types of planktonic larvae. This potential indirect effect of OA via trophic interactions, however, has not been fully explored. In this study, veligers of Crepidula onyx were exposed to different pH levels representing the ambient (as control) and low pH values (pH 7.7 and pH 7.3) for 14 days, and were fed with Isochrysis galbana cultured at these three respective pHs...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28929492/potent-antitumor-effect-of-tumor-microenvironment-targeted-oncolytic-adenovirus-against-desmoplastic-pancreatic-cancer
#18
Yan Li, JinWoo Hong, Joung-Eun Oh, A-Rum Yoon, Chae-Ok Yun
Pancreatic cancer is a leading cause of cancer-related death. Desmoplastic pancreatic tumors exhibit excessive extracellular matrix (ECM) and are thus highly resistant to anticancer therapeutics, since the ECM restricts drug penetration and dispersion. Here, we designed and generated two hypoxia-responsive and cancer-specific hybrid promoters, H(mT)E and H(E)mT. Transgene expression driven by each hybrid promoter was markedly higher under hypoxic conditions than normoxic conditions. Moreover, H(E)mT-driven transgene expression was highly cancer-specific and was superior to that of H(mT)E-driven expression...
September 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28890009/impact-of-onyx%C3%A2-embolization-on-radiosurgical-management-of-cerebral-avm-treatment-and-outcome
#19
Ido Strauss, Oz Haim, Daniel Umansky, Benjamin W Corn, Vladimir Frolov, Natan Shtraus, Shimon Maimon, Andrew A Kanner
BACKGROUND: Stereotactic radiosurgery (SRS) is a well-established treatment modality for cerebral arterio-venous malformations (AVMs). The main limiting factor in the radiosurgical treatment of AVMs is the volume of the nidus with high-grade lesions often requiring combined treatment to reduce the SRS target volume. To overcome this limitation, we have been using a combined treatment approach consisting of endovascular embolization with ONYX followed by SRS. OBJECTIVE: To evaluate our clinical experience for safety and feasibility of this multimodality treatment approach...
September 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28882716/remote-thoracic-myelopathy-from-a-spinal-dural-arteriovenous-fistula-at-the-cranio-cervical-junction-case-report-and-review-of-literature
#20
Michael J Lang, Stavropoula Tjoumakaris, Robert H Rosenwasser, Pascal Jabbour
BACKGROUND: The cranio-cervical junction is a rare location for spinal dural arteriovenous fistulas (dAVF). Typically, fistulas at this location present with findings related to intracranial cortical venous reflux or with cervical myelopathy. We present a case of cranio-cervical junction dAVF with isolated clinical and radiographic findings of thoracolumbar myelopathy. CASE DESCRIPTION: A 54 year-old male presented with subacute onset of lower extremity weakness, paresthesias and gait dysfunction...
September 4, 2017: World Neurosurgery
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