Alexandre Joushomme, André Garenne, Mélody Dufossée, Rémy Renom, Hermanus Johannes Ruigrok, Yann Loick Chappe, Anne Canovi, Lorenza Patrignoni, Annabelle Hurtier, Florence Poulletier de Gannes, Isabelle Lagroye, Philippe Lévêque, Noëlle Lewis, Muriel Priault, Delia Arnaud-Cormos, Yann Percherancier
It remains controversial whether exposure to environmental radiofrequency signals (RF) impacts cell status or response to cellular stress such as apoptosis or autophagy. We used two label-free techniques, cellular impedancemetry and Digital Holographic Microscopy (DHM), to assess the overall cellular response during RF exposure alone, or during co-exposure to RF and chemical treatments known to induce either apoptosis or autophagy. Two human cell lines (SH-SY5Y and HCT116) and two cultures of primary rat cortex cells (astrocytes and co-culture of neurons and glial cells) were exposed to RF using an 1800 MHz carrier wave modulated with various environmental signals (GSM: Global System for Mobile Communications, 2G signal), UMTS (Universal Mobile Telecommunications System, 3G signal), LTE (Long-Term Evolution, 4G signal, and Wi-Fi) or unmodulated RF (continuous wave, CW)...
January 8, 2022: International Journal of Molecular Sciences