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https://www.readbyqxmd.com/read/28899843/a-machine-learning-approach-for-the-identification-of-new-biomarkers-for-knee-osteoarthritis-development-in-overweight-and-obese-women
#1
N Lazzarini, J Runhaar, A C Bay-Jensen, C S Thudium, S M A Bierma-Zeinstra, Y Henrotin, J Bacardit
OBJECTIVE: Knee osteoarthritis (OA) is among the higher contributors to global disability. Despite its high prevalence, currently, there is no cure for this disease. Furthermore, the available diagnostic approaches have large precision errors and low sensitivity. Therefore, there is a need for new biomarkers to correctly identify early knee OA. METHOD: We have created an analytics pipeline based on machine learning to identify small models (having few variables) that predict the 30-months incidence of knee OA (using multiple clinical and structural OA outcome measures) in overweight middle-aged women without knee OA at baseline...
September 9, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28893573/measurement-of-nutritional-status-using-body-mass-index-waist-to-hip-ratio-and-waist-circumference-to-predict-treatment-outcome-in-females-and-males-with-acute-first-ever-ischemic-stroke
#2
Jan Paweł Bembenek, Michał Karlinski, Maciej Niewada, Iwona Kurkowska-Jastrzębska, Anna Członkowska
BACKGROUND: We aimed to investigate whether increased waist-to-hip ratio (WHR), waist circumference (WC), or improper body mass index (BMI) may differently predict short-term outcomes in females and males with first-ever acute ischemic stroke. METHODS: This was a retrospective study of consecutive patients (1109 females and 939 males) admitted for first-ever ischemic stroke between 2003 and 2015. Data were collected in a detailed hospital stroke registry. BMI of 18...
September 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28892239/impact-of-physical-activity-on-obesity-and-lipid-profile-of-adults-with-intellectual-disability
#3
Krystyna Gawlik, Anna Zwierzchowska, Diana Celebańska
INTRODUCTION: This study assessed overweight, obesity and lipid profiles in adults with intellectual disability and compared these metrics with their physical activity. MATERIALS AND METHOD: Basic somatic parameters, lipid profile and weekly physical activity were examined in 27 adults with moderate intellectual disability. Chi-square independence tests and Pearson's linear correlation coefficients were used. RESULTS: The participants had excess body mass, excess body fat and abdominal obesity...
September 11, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28818714/the-role-of-physical-activity-in-improving-physical-fitness-in-children-with-intellectual-and-developmental-disabilities
#4
Kyla Collins, Kerri Staples
BACKGROUND: One in three children in North America are considered overweight or obese. Children with intellectual and developmental disabilities (IDD) are at an increased risk for obesity than their typically developing peers. Decreased physical activity (PA) and low physical fitness may be contributing factors to this rise in obesity. AIM: Because children with IDD are at an increased risk of diseases related to inactivity, it is important to improve health-related physical fitness to complete activities of daily living and improve health...
August 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28818234/the-dutch-lymphedema-guidelines-based-on-the-international-classification-of-functioning-disability-and-health-and-the-chronic-care-model
#5
Robert J Damstra, Anne-Berth Halk
Lymphedema is a chronic and progressive condition due to an imbalance between lymphatic filtration and transport capacity. A relative overload of fluid is caused by lymphatic impairment (afterload impairment); an absolute overload is caused by increased filtration (preload raised). Lymphedema can result in considerable disability and loss of quality of life. The Dutch Society of Dermatology organized a task force to create guidelines using the International Classification of Functioning, Disability, and Health...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28803172/influence-of-obesity-on-complications-clinical-outcome-and-subsidence-following-anterior-lumbar-interbody-fusion-alif-prospective-observational-study
#6
Kevin Phan, Priya Rogers, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: The complications associated with obesity have been well described for posterior lumbar spinal surgery. However, the influence of obesity on anterior lumbar interbody fusion (ALIF) is not well established. We aimed to compare complication risks, functional outcomes and subsidence rates in normal, overweight and obese patients who underwent ALIF. METHODS: 137 consecutive patients undergoing ALIF surgery from 2012-2014 were prospectively followed. Patients were categorized into 3 groups according to their body mass index (BMI)...
August 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28802895/physical-activity-and-obesity-among-nine-year-old-children-with-and-without-chronic-health-problems-illness-or-disabilities-in-ireland
#7
Justin A Haegele, Sean Healy, Xihe Zhu
BACKGROUND: Regular engagement in physical activity can help youth control their weight during childhood while decreasing one's chances of developing chronic diseases (e.g., coronary heart disease, diabetes) throughout the lifespan. While numerous studies have explored physical activity participation and weight status among typically developing children, few epidemiological studies utilizing nationally representative data has focused on children with chronic health problems, illness, or disabilities (CHID)...
August 8, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28776243/burden-of-obesity-in-the-eastern-mediterranean-region-findings-from-the-global-burden-of-disease-2015-study
#8
Ali H Mokdad
OBJECTIVES: We used the Global Burden of Disease (GBD) 2015 study results to explore the burden of high body mass index (BMI) in the Eastern Mediterranean Region (EMR). METHODS: We estimated the prevalence of overweight and obesity among children (2-19 years) and adults (≥20 years) in 1980 and 2015. The burden of disease related to high BMI was calculated using the GBD comparative risk assessment approach. RESULTS: The prevalence of obesity increased for adults from 15...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28754212/health-promotion-research-in-active-duty-army-soldiers-the-road-to-a-fit-and-ready-force
#9
Mary S McCarthy, Evelyn B Elshaw, Barbara M Szekely, Bethann Pflugeisen
BACKGROUND: In the last decade the Military Health System has changed its paradigm to focus on health promotion and disease prevention. PURPOSE: This paper reviews a decade of research exploring the effects of military life on nutritional status and bone health of Army soldiers. METHOD: Descriptive and experimental approaches have assessed occupational demands on soldiers in variable environments that require optimal nutrition status and physical health...
July 5, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28719557/functional-gain-and-pain-relief-after-total-joint-replacement-according-to-obesity-status
#10
MULTICENTER STUDY
Wenjun Li, David C Ayers, Courtland G Lewis, Thomas R Bowen, Jeroan J Allison, Patricia D Franklin
BACKGROUND: Obesity has been associated with lower function and more pain before and after total hip or knee replacement (THR or TKR). We examined the changes between preoperative and postoperative function and pain in a large representative U.S. cohort to determine if there was a relationship to obesity status. METHODS: Preoperative and 6-month postoperative data on function (Short Form-36 Physical Component Summary [PCS] score), joint pain (Hip disability and Osteoarthritis Outcome Score and Knee injury and Osteoarthritis Outcome Score), and body mass index (BMI) were collected from a national sample of 2,040 patients who had undergone THR and 2,964 who had undergone TKR from May 2011 to March 2013...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28707359/the-feasibility-of-using-pedometers-for-self-report-of-steps-and-accelerometers-for-measuring-physical-activity-in-adults-with-intellectual-and-developmental-disabilities-across-an-18-month-intervention
#11
L T Ptomey, E A Willis, J Lee, R A Washburn, C A Gibson, J J Honas, J E Donnelly
BACKGROUND: Improving physical activity in adults with intellectual and developmental disabilities (IDDs) is recommended to improve weight loss and general health. However, in order to determine the success of physical activity interventions, identification of feasible methods for assessment of physical activities is necessary. The purpose of this study is to assess the feasibility of adults with IDD to track daily steps and wear an accelerometer. METHODS: Overweight/obese adults with mild to moderate IDD followed a diet and physical activity program for 18 months...
August 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28674135/mechanism-evaluation-of-a-lifestyle-intervention-for-patients-with-musculoskeletal-pain-who-are-overweight-or-obese-protocol-for-a-causal-mediation-analysis
#12
Hopin Lee, John Wiggers, Steven J Kamper, Amanda Williams, Kate M O'Brien, Rebecca K Hodder, Luke Wolfenden, Sze Lin Yoong, Elizabeth Campbell, Robin Haskins, Emma K Robson, James H McAuley, Christopher M Williams
INTRODUCTION: Low back pain (LBP) and knee osteoarthritis (OA) are highly prevalent and disabling conditions that cause societal and economic impact worldwide. Two randomised controlled trials (RCTs) will evaluate the effectiveness of a multicomponent lifestyle intervention for patients with LBP and knee OA who are overweight or obese. The key targets of this intervention are to improve physical activity, modify diet and correct pain beliefs. These factors may explain how a lifestyle intervention exerts its effects on key patient-relevant outcomes: pain, disability and quality of life...
July 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28661952/victimization-by-siblings-in-children-with-disability-or-weight-problems
#13
Corinna J Tucker, David Finkelhor, Heather Turner
OBJECTIVE: Children with a physical disability, psychological disorder, or of nonnormative weight are often targets of peer victimization. Sibling victimization, however, is more common than peer victimization, but rarely explored. We investigated linkages between sibling victimization and whether children had a physical disability, psychological disorder (i.e., internalizing disorder, attention deficit disorder/attention-deficit hyperactivity disorder), and were perceived by parents as being thinner than average or overweight...
July 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28637725/filling-the-gaps-in-sards-research-collection-and-linkage-of-administrative-health-data-and-self-reported-survey-data-for-a-general-population-based-cohort-of-individuals-with-and-without-diagnoses-of-systemic-autoimmune-rheumatic-disease-sards-from-british
#14
Natalie McCormick, Kathryn Reimer, Ali Famouri, Carlo A Marra, J Antonio Aviña-Zubieta
PURPOSE: Systemic autoimmune rheumatic diseases (SARDs) are a group of debilitating autoimmune diseases, including systemic lupus erythematosus and related disorders. Assessing the healthcare and economic burden of SARDs has been challenging: while administrative databases can be used to determine healthcare utilisation and costs with minimal selection and recall bias, other health, sociodemographic and economic data have typically been sourced from highly selected, clinic-based cohorts...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28636076/prevalence-and-impact-of-obesity-in-people-with-haemophilia-review-of-literature-and-expert-discussion-around-implementing-weight-management-guidelines
#15
REVIEW
S Kahan, A Cuker, R F Kushner, J Maahs, M Recht, T Wadden, T Willis, S Majumdar, D Ungar, D Cooper
Obesity affects more than 35% of Americans, increasing the risk of more than 200 comorbid conditions, impaired quality of life and premature mortality. This review aimed to summarize literature published over the past 15 years regarding the prevalence and impact of obesity in people with haemophilia (PWH) and to discuss implementing general guidelines for weight management in the context of the haemophilia comprehensive care team. Although few studies have assessed the effects of obesity on haemophilia-specific outcomes, existing evidence indicates an important impact of weight status on lower extremity joint range of motion and functional disability, with potentially important effects on overall quality of life...
June 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28608804/phytosterols-and-omega-3-supplementation-exert-novel-regulatory-effects-on-metabolic-and-inflammatory-pathways-a-proteomic-study
#16
Carmen Lambert, Judit Cubedo, Teresa Padró, Joan Sánchez-Hernández, Rosa M Antonijoan, Antonio Perez, Lina Badimon
Cardiovascular disease (CVD) remains one of the major causes of death and disability worldwide. In addition to drug treatment, nutritional interventions or supplementations are becoming a health strategy for CVD prevention. Phytosterols (PhyS) are natural components that have been shown to reduce cholesterol levels; while poly-unsaturated fatty acids (PUFA), mainly omega-3 (ω3) fatty acids, have shown to reduce triglyceride levels. Here we aimed to investigate whether the proteins in the main lipoproteins (low density lipoproteins (LDL) and high density lipoproteins (HDL)) as well as proteins in the lipid free plasma fraction (LPDP) were regulated by the intake of PhyS-milk or ω3-milk, in overweight healthy volunteers by a proteomic based systems biology approach...
June 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28606705/improving-food-choices-and-nutrient-adequacy-in-adolescents-young-adults-with-developmental-disabilities
#17
Regina M Subach
BACKGROUND: Persons with intellectual and developmental disabilities (DD) have higher incidences of overweight and obesity than the general population and are currently underserved in health promotion programs. Restricted diets due to sensory sensitivity and physiological difference are often followed by persons with DD resulting in nutrient inadequacies, which may contribute to overweight and obesity. Closing the gap of healthcare disparities for persons with DD must start by increasing awareness of factors causing overweight and obesity, and development of strategies and programs to reduce incidences of overweight and obesity for persons with DD...
June 1, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28591350/factors-associated-with-chronic-back-pain-in-adults-in-brazil
#18
Deborah Carvalho Malta, Max Moura de Oliveira, Silvânia Suely Caribé de Araújo Andrade, Waleska Teixeira Caiaffa, Maria de Fatima Marinho de Souza, Regina Tomie Ivata Bernal
OBJECTIVE: To identify associations of chronic back pain with sociodemographic characteristics, lifestyles, body mass index, self-reported chronic diseases and health assessment, according to sex. METHODS: We analyzed data from the 2013 National Health Survey, estimated the prevalence and their respective 95% confidence intervals (95%CI) of chronic back pain, according to selected variables and performed adjustment by age and education. RESULTS: 18...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28577864/cigarette-smoking-alcohol-consumption-and-overweight-in-multiple-sclerosis-disability-progression
#19
Wayra Citlali Paz-Ballesteros, Eric Alejandro Monterrubio-Flores, José de Jesús Flores-Rivera, Teresa Corona-Vázquez, Carlos Hernández-Girón
BACKGROUND: The rate at which disability progresses in multiple sclerosis (MS), and its severity, have been associated with modifiable lifestyle habits. OBJECTIVE: To investigate the risk of disability progression in MS patients according to tobacco and alcohol consumption and to the presence of overweight. METHODS: This was a follow-up of MS cases from a concluded case-control study (National Institute of Neurology and Neurosurgery, Mexico 2010-2013)...
January 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/28573749/obesity-impedes-functional-improvement-in-youth-with-chronic-pain-an-initial-investigation
#20
A M Stoner, K E Jastrowski Mano, S J Weisman, K R Hainsworth
BACKGROUND: Youth with chronic pain are at higher risk for obesity than the general population. In youth with chronic pain, obesity exacerbates pain-specific activity limitations, and in adults with chronic pain, obesity perpetuates a cycle of disability. The current study examined whether weight status predicts functional disability outcomes over time in youth with chronic pain. METHODS: Data were obtained from a retrospective chart review of patients who consented to participate in a longitudinal outcomes study...
June 2, 2017: European Journal of Pain: EJP
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