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https://www.readbyqxmd.com/read/28918309/health-and-wellbeing-during-transition-to-adulthood-for-young-people-with-intellectual-disabilities-a-qualitative-study
#1
Genevieve Young-Southward, Sally-Ann Cooper, Christopher Philo
BACKGROUND: Transition to adulthood may have negative consequences for health and wellbeing in individuals with intellectual disabilities (ID), but this aspect of transition has received little investigation. This qualitative study aimed to explore the transition experiences of individuals with ID from their own perspectives, and from that of their parents, in order to identify health or wellbeing implications of transition. METHOD: Semi-structured interviews were conducted with 17 young people with mild, moderate and severe ID aged 16-27 years and with 23 parents of young people with mild, moderate, severe and profound ID aged 16-26 years...
September 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28910267/surveillance-for-certain-health-behaviors-and-conditions-among-states-and-selected-local-areas-behavioral-risk-factor-surveillance-system-united-states-2013-and-2014
#2
Sonya Gamble, Tebitha Mawokomatanda, Fang Xu, Pranesh P Chowdhury, Carol Pierannunzi, David Flegel, William Garvin, Machell Town
PROBLEM: Chronic diseases and conditions (e.g., heart diseases, stroke, arthritis, and diabetes) are the leading causes of morbidity and mortality in the United States. These conditions are costly to the U.S. economy, yet they are often preventable or controllable. Behavioral risk factors (e.g., excessive alcohol consumption, tobacco use, poor diet, frequent mental distress, and insufficient sleep) are linked to the leading causes of morbidity and mortality. Adopting positive health behaviors (e...
September 15, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28906236/ranked-performance-of-canada-s-health-system-on-the-international-stage-a-scoping-review
#3
Said Ahmad Maisam Najafizada, Thushara Sivanandan, Kelly Hogan, Deborah Cohen, Jean Harvey
INTRODUCTION: Since the release of the World Health Report in 2000, health system performance ranking studies have garnered significant health policy attention. However, this literature has produced variable results. The objective of this study was to synthesize the research and analyze the ranked performance of Canada's health system on the international stage. METHOD: We conducted a scoping review exploring Canada's place in ranked health system performance among its peer Organisation for Economic Co-operation and Development countries...
August 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/28899843/a-machine-learning-approach-for-the-identification-of-new-biomarkers-for-knee-osteoarthritis-development-in-overweight-and-obese-women
#4
N Lazzarini, J Runhaar, A C Bay-Jensen, C S Thudium, S M A Bierma-Zeinstra, Y Henrotin, J Bacardit
OBJECTIVE: Knee osteoarthritis (OA) is among the higher contributors to global disability. Despite its high prevalence, currently, there is no cure for this disease. Furthermore, the available diagnostic approaches have large precision errors and low sensitivity. Therefore, there is a need for new biomarkers to correctly identify early knee OA. METHOD: We have created an analytics pipeline based on machine learning to identify small models (having few variables) that predict the 30-months incidence of knee OA (using multiple clinical and structural OA outcome measures) in overweight middle-aged women without knee OA at baseline...
September 9, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28898445/characterizing-adults-with-type-2-diabetes-mellitus-and-intellectual-disability-outcomes-of-a-case-finding-study
#5
L D Bryant, A M Russell, R E A Walwyn, A J Farrin, A Wright-Hughes, E H Graham, D Nagi, A Stansfield, J Birtwistle, S Meer, R A Ajjan, A O House
AIMS: To report the results of a case-finding study conducted during a feasibility trial of a supported self-management intervention for adults with mild to moderate intellectual disability and Type 2 diabetes mellitus, and to characterize the study sample in terms of diabetes control, health, and access to diabetes management services and support. METHODS: We conducted a cross-sectional case-finding study in the UK (March 2013 to June 2015), which recruited participants mainly through primary care settings...
September 12, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28892239/impact-of-physical-activity-on-obesity-and-lipid-profile-of-adults-with-intellectual-disability
#6
Krystyna Gawlik, Anna Zwierzchowska, Diana Celebańska
INTRODUCTION: This study assessed overweight, obesity and lipid profiles in adults with intellectual disability and compared these metrics with their physical activity. MATERIALS AND METHOD: Basic somatic parameters, lipid profile and weekly physical activity were examined in 27 adults with moderate intellectual disability. Chi-square independence tests and Pearson's linear correlation coefficients were used. RESULTS: The participants had excess body mass, excess body fat and abdominal obesity...
September 11, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28889010/pain-in-osteoarthritis-implications-for-optimal-management
#7
Anne-Priscille Trouvin, Serge Perrot
Pain is an ubiquitous symptom in osteoarticular diseases, occurring much more commonly than stiffness or disability. OA of the knee, hand, or hip affects around 20% of adults in various populations and is dramatically increasing in many countries, mostly related to age and obesity, leading to an increased number of people having OA pain, and creating a huge burden related to disability and health care costs. OA-related pain, has been classically considered to be a nociceptive pain condition. Clinicians have considered pain to be an alarm signal, correlated to the intensity of joint degradation...
September 6, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28884562/%C3%A3-mpsq-short-score-and-determinants-of-chronic-pain-cross-sectional-results-from-a-middle-aged-birth-cohort
#8
Olli Ruokolainen, Juha Auvinen, Steven J Linton, Sauli Herrala, Pasi Eskola, Markus Paananen, Raija Korpelainen, Jaro Karppinen
BACKGROUND: The Örebro Musculoskeletal Pain Screening Questionnaire (ÖMPSQ) was developed to identify patients at risk of developing work disability due to pain. So far, neither the ÖMPSQ nor its short version (ÖMSPQ-short) have been tested in population-based samples. AIM: We examined the associations between several well-known determinants for chronic pain and ÖMPSQ-short score. DESIGN: Cross-sectional study. SETTING: All measurements and tests were made at the University of Oulu...
September 7, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28883422/effect-of-metabolic-syndrome-on-the-functional-outcome-of-corticosteroid-injection-for-lateral-epicondylitis-retrospective-matched-case-control-study
#9
Young Hak Roh, Minjoon Oh, Jung Ho Noh, Hyun Sik Gong, Goo Hyun Baek
Both obesity and diabetes mellitus are well-known risk factors for tendinopathies. We retrospectively compared the efficacy of single corticosteroid injections in treating lateral epicondylitis in patients with and without metabolic syndrome (MetS). Fifty-one patients with lateral epicondylitis and MetS were age- and sex-matched with 51 controls without MetS. Pain severity, Disability of the Arm, Shoulder, and Hand score, and grip strength were assessed at base line and at 6, 12 and 24 weeks post-injection...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28880839/differences-between-younger-and-older-us-adults-with-multiple-chronic-conditions
#10
Mary L Adams
INTRODUCTION: Adults with multiple (≥2) chronic conditions (MCCs) account for a large portion of US health care costs. Despite the increase in MCC rates with age, most people with MCCs are working age. The study objective was to compare adults with MCCs who were younger than 65 years with those aged 65 years or older on selected measures to better understand the differences between groups and inform interventions that could lower health care costs. METHODS: Data from respondents to the 2015 Behavioral Risk Factor Surveillance System data (N = 201,711) were used to compare adults aged 65 or older with MCCs with those younger than 65 with MCCs in unadjusted and adjusted analyses on chronic conditions, quality of life measures, disability status, access to health care, and modifiable risk factors...
September 7, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28873810/managing-weight-what-do-people-with-an-intellectual-disability-want-from-mobile-technology
#11
Phil Smyth, Claire McDowell, Julian C Leslie, Geraldine Leader, Mark Donnelly, Elizabeth Simpson, Laura Skelly
Obesity is a significant health challenge. People with Intellectual Disability (ID) are particularly vulnerable to developing obesity. Mobile technology has been developed to support the management of weight and obesity in the form of apps, although not with people with an ID in mind. As a result existing off-the-shelf weight management apps currently available may not be functional in supporting weight reduction within this population. This paper presents the results of consultations with people with ID regarding weight management, comfort with mobile technology and desired characteristics in apps designed for people with ID that target weight management...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28859567/the-hypothalamus-at-the-crossroads-of-psychopathology-and-neurosurgery
#12
Daniel A N Barbosa, Ricardo de Oliveira-Souza, Felipe Monte Santo, Ana Carolina de Oliveira Faria, Alessandra A Gorgulho, Antonio A F De Salles
The neurosurgical endeavor to treat psychiatric patients may have been part of human history since its beginning. The modern era of psychosurgery can be traced to the heroic attempts of Gottlieb Burckhardt and Egas Moniz to alleviate mental symptoms through the ablation of restricted areas of the frontal lobes in patients with disabling psychiatric illnesses. Thanks to the adaptation of the stereotactic frame to human patients, the ablation of large volumes of brain tissue has been practically abandoned in favor of controlled interventions with discrete targets...
September 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28859103/myt1l-mutations-cause-intellectual-disability-and-variable-obesity-by-dysregulating-gene-expression-and-development-of-the-neuroendocrine-hypothalamus
#13
Patricia Blanchet, Martina Bebin, Shaam Bruet, Gregory M Cooper, Michelle L Thompson, Benedicte Duban-Bedu, Benedicte Gerard, Amelie Piton, Sylvie Suckno, Charu Deshpande, Virginia Clowes, Julie Vogt, Peter Turnpenny, Michael P Williamson, Yves Alembik, Eric Glasgow, Alisdair McNeill
Deletions at chromosome 2p25.3 are associated with a syndrome consisting of intellectual disability and obesity. The smallest region of overlap for deletions at 2p25.3 contains PXDN and MYT1L. MYT1L is expressed only within the brain in humans. We hypothesized that single nucleotide variants (SNVs) in MYT1L would cause a phenotype resembling deletion at 2p25.3. To examine this we sought MYT1L SNVs in exome sequencing data from 4, 296 parent-child trios. Further variants were identified through a genematcher-facilitated collaboration...
August 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28855269/roles-of-increased-glycemic-variability-glp-1-and-glucagon-in-hypoglycaemia-after-roux-en-y-gastric-bypass
#14
George Tharakan, Preeshila Behary, Nicolai Jacob Wewer Albrechtsen, Harvinder Chahal, Julia Kenkre, Alexander D Miras, Ahmed R Ahmed, Jens Juul Holst, Steve R Bloom, Tricia Mei Mei Tan
Objective Roux-en-Y Gastric Bypass (RYGB) surgery is currently the most effective treatment for diabetes and obesity. An increasingly recognized complication of RYGB surgery is postprandial hypoglycemia (PPH). The pathophysiology of PPH remains unclear with multiple mechanisms suggested including nesidioblastosis, altered insulin clearance and increased glucagon-like-1 peptide (GLP-1) secretion. Whilst many PPH patients respond to dietary modification, some have severely disabling symptoms. Multiple treatments have been trialled ranging from acarbose, to both GLP-1 agonists and antagonists, even to reversal of RYGB...
August 30, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28846633/strawberries-improve-pain-and-inflammation-in-obese-adults-with-radiographic-evidence-of-knee-osteoarthritis
#15
Jace Schell, R Hal Scofield, James R Barrett, Biji T Kurien, Nancy Betts, Timothy J Lyons, Yan Daniel Zhao, Arpita Basu
Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, impaired joint function, and reduced quality of life. Dietary polyphenols and other bioactive compounds in berries, curcumin, and tea have shown effects in ameliorating pain and inflammation in OA, but few clinical studies have been reported. The purpose of the present study was to examine the effects of dietary strawberries on pain, markers of inflammation, and quality of life indicators in obese adults with OA of the knee...
August 28, 2017: Nutrients
https://www.readbyqxmd.com/read/28845486/the-effects-of-chronic-medical-conditions-and-obesity-on-self-reported-disability-in-older-mexican-americans
#16
Sanggon Nam, Soham Al Snih, Kyriakos Markides
We investigated the effect of chronic medical conditions including obesity on self-reported disability and mobility in Mexican Americans aged 75 or over using data from the Hispanic Established Population for the Epidemiological Study of the Elderly (Hispanic EPESE) Wave 5 (2004-2005). Disability was assessed with a modified version of the Katz activities of daily living (ADL) scale and mobility was assessed with the Rosow Breslau scale of gross mobility function. The percentage of participants needing assistance with ADLs were as follows: 26...
2017: Texas Public Health Journal
https://www.readbyqxmd.com/read/28842821/association-between-obesity-and-migraine-in-women
#17
REVIEW
Jelena M Pavlovic, Julio R Vieira, Richard B Lipton, Dale S Bond
PURPOSE OF REVIEW: Migraine is a common and highly disabling condition that is particularly prevalent among women and especially women of reproductive age. The tremendous rise in adiposity in the Western world has led to an epidemic of obesity in women. The particular effects of obesity on women with migraine of various ages are the focus of this review. RECENT FINDINGS: Conflicting findings from various studies with different approaches and populations have made challenging definitive conclusions about associations between migraine and obesity...
August 25, 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28832428/functional-capacity-depends-on-lower-limb-muscle-strength-rather-than-on-abdominal-obesity-in-active-postmenopausal-women
#18
Maude C Dulac, Livia Pinheiro Carvalho, Mylène Aubertin-Leheudre
OBJECTIVE: An association has been found between abdominal obesity and functional capacity (FC) in the literature where waist circumference has been used to infer abdominal obesity. However, most studies focused on evaluating predictors of FC and functional disabilities only in sedentary people. This study aimed to examine whether abdominal obesity is associated with FC in physically active postmenopausal women. METHODS: Forty-four active (>7,500 steps/d) postmenopausal women were recruited...
August 21, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28831953/a-cluster-randomised-control-trial-of-a-multi-component-weight-management-programme-for-adults-with-intellectual-disabilities-and-obesity
#19
RANDOMIZED CONTROLLED TRIAL
Leanne Harris, Catherine Hankey, Nathalie Jones, Carol Pert, Heather Murray, Janet Tobin, Susan Boyle, Craig Melville
There have been few published controlled studies of multi-component weight management programmes that include an energy deficit diet (EDD), for adults with intellectual disabilities and obesity. The objective of this study was to conduct a single-blind, cluster randomised controlled trial comparing a multi-component weight management programme to a health education programme. Participants were randomised to either TAKE 5, which included an EDD or Waist Winners Too (WWToo), based on health education principles...
August 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28827086/risk-factors-for-erectile-dysfunction-in-men-with-htlv-1
#20
Cassius José Vitor de Oliveira, José Abraão Carneiro Neto, Rosana C P Andrade, Paulo Novis Rocha, Edgar Marcelino de Carvalho Filho
BACKGROUND: Erectile dysfunction (ED) occurs in more than 50% of patients with human T-cell lymphotropic virus type 1 (HTLV-1) infection. In the general population, atherosclerosis is the main risk factor related to ED. AIM: To compare the contribution of neurologic disorders from HTLV-1 with that of atherosclerosis as risk factors for ED in men with HTLV-1. METHODS: In this cross-sectional study, men 18 to 70 years old with HTLV-1 were classified into one of two groups according to the presence or absence of ED...
August 18, 2017: Journal of Sexual Medicine
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