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https://www.readbyqxmd.com/read/29049554/genetic-association-of-major-depression-with-atypical-features-and-obesity-related-immunometabolic-dysregulations
#1
Yuri Milaneschi, Femke Lamers, Wouter J Peyrot, Bernhard T Baune, Gerome Breen, Abbas Dehghan, Andreas J Forstner, Hans J Grabe, Georg Homuth, Carol Kan, Cathryn Lewis, Niamh Mullins, Matthias Nauck, Giorgio Pistis, Martin Preisig, Margarita Rivera, Marcella Rietschel, Fabian Streit, Jana Strohmaier, Alexander Teumer, Sandra Van der Auwera, Naomi R Wray, Dorret I Boomsma, Brenda W J H Penninx
Importance: The association between major depressive disorder (MDD) and obesity may stem from shared immunometabolic mechanisms particularly evident in MDD with atypical features, characterized by increased appetite and/or weight (A/W) during an active episode. Objective: To determine whether subgroups of patients with MDD stratified according to the A/W criterion had a different degree of genetic overlap with obesity-related traits (body mass index [BMI] and levels of C-reactive protein [CRP] and leptin)...
October 18, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29046007/-dietary-recommendations-in-metabolic-vascular-syndrome
#2
Katharina Lechner, Nicole Erickson, Benjamin Lechner, Florian Horn
Cardiovascular disease is the number one cause of death globally. Poor diet constitutes a key factor in the initiation and progression of cardiovascular disease and has become the leading risk factor for disability and death worldwide. Therefore, addressing suboptimal nutrition is of key prognostic relevance in primary and secondary prevention of metabolic vascular syndrome.Metabolic vascular syndrome is a multidimensional network of acquired cardiometabolic risk factors closely related to insulin resistance (IR) and concomitant hyperinsulinemia...
October 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29038412/-effects-of-high-frequency-jet-ventilation-on-respiratory-failure-after-total-arch-replacement-due-to-acute-aortic-dissection-with-morbid-obesity-report-of-a-case
#3
Motoyuki Kumagai, Junichiro Nishizawa, Kazuhiro Takatoku, Takashi Ohba
A 55-year-old morbidly obese woman [body mass index (BMI) 51.2] developed acute type A aortic dissection, and she also presented with significant hypoxemia and hypercapnia. She underwent a successful emergency total arch replacement, but severe hypoxemia persisted and Pao2/Fio2 lowered to 71.9 mmHg. We therefore applied high frequency jet ventilation (HFJV), which soon improved the hypoxemia without hemodynamic compromise. HFJV was discontinued three days later, when her Pao2/Fio2 improved to 170.0 mmHg. Weaning from the respirator was initiated on postoperative day 13...
October 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29035104/association-between-discrimination-and-obesity-in-african-american-men
#4
Roland J Thorpe, Lauren J Parker, Ryon J Cobb, Felicia Dillard, Janice Bowie
The objective of this study was to examine the association between discrimination and obesity among a U.S. nationally representative sample of African-American men. Data from the 2001-2003 National Survey of American Life (NSAL) were used to collect measures of everyday and major discrimination, and body mass index (BMI) taken from self-reports. Poisson regression with robust standard errors was applied to estimate the prevalence ratios of everyday and major discrimination as it relates to obesity (BMI ≥ 30 kg/m(2)), controlling for potential confounders...
2017: Biodemography and Social Biology
https://www.readbyqxmd.com/read/29031012/the-role-of-diabetes-mellitus-and-bmi-in-the-surgical-treatment-of-ankle-fractures
#5
Riccardo Maria Lanzetti, Domenico Lupariello, Teresa Venditto, Matteo Guzzini, Antonio Ponzo, Angelo De Carli, Andrea Ferretti
BACKGROUND: Open reduction and internal fixation is the standard treatment for displaced ankle fractures. However, the presence of comorbidities such as diabetes mellitus and BMI is associated with poor bone quality, and these factors may predict the development of postoperative complications. The study aim was to assess the role of diabetes mellitus and BMI in wound healing in patients younger than 65 years who were surgically treated for malleoli fractures. METHODS: Ninety patients, aged from 18 to 65 years old, with surgically treated ankle fracture, were retrospectively enrolled...
October 14, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29017479/psychosocial-benefits-of-workplace-physical-exercise-cluster-randomized-controlled-trial
#6
Markus D Jakobsen, Emil Sundstrup, Mikkel Brandt, Lars L Andersen
BACKGROUND: While benefits of workplace physical exercise on physical health is well known, little is known about the psychosocial effects of such initiatives. This study evaluates the effect of workplace versus home-based physical exercise on psychosocial factors among healthcare workers. METHODS: A total of 200 female healthcare workers (Age: 42.0, BMI: 24.1) from 18 departments at three hospitals were cluster-randomized to 10 weeks of: 1) home-based physical exercise (HOME) performed alone during leisure time for 10 min 5 days per week or 2) workplace physical exercise (WORK) performed in groups during working hours for 10 min 5 days per week and up to 5 group-based coaching sessions on motivation for regular physical exercise...
October 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28983413/correlations-between-ultrasonographic-findings-clinical-scores-and-depression-in-patients-with-knee-osteoarthritis
#7
Samia M Abd El Monaem, Nashwa Ismail Hashaad, Noha Hosni Ibrahim
OBJECTIVE: This study aimed to explore correlations between the presence of depression, clinical scores, and ultrasonographic (US) grading in osteoarthritis (OA) patients and to clarify if depressive symptoms might cause a discrepancy between US findings and clinical scores. MATERIAL AND METHODS: Two hundred patients with primary knee OA and 100 healthy hospital volunteers of the same age and sex not complaining of knee troubles participated in this study. We evaluated depressive symptoms in all participants using the Beck Depression Inventory (BDI) scale...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28977630/the-limited-cutaneous-form-of-systemic-sclerosis-is-associated-with-urinary-incontinence-an-international-multicentre-study
#8
Gregor John, Yannick Allanore, Pamela Polito, Silvia Piantoni, Micaela Fredi, Jérôme Avouac, Franco Franceschini, Marie-Elise Truchetet, Franco Cozzi, Paolo Airo, Carlo Chizzolini
Objectives: The aim of this study was to explore the association between urinary incontinence (UI) and the main clinical and serological subsets of SSc, to assess risk factors for UI and its impact on quality of life (QoL). Methods: UI and QoL were assessed through self-administered questionnaires in 334 patients with SSc from five European tertiary centres. Logistic regressions were performed to test the association between clinical forms, serological status and UI and to adjust for confounders...
August 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28966290/oral-function-and-nutritional-status-among-the-elderly-with-facial-and-oral-tactile-hypersensitivity-who-are-under-long-term-care
#9
Maki Shirobe, Rena Nakayama, Hirohiko Hirano, Yuki Ohara, Keiko Endo, Yutaka Watanabe, Chiyoko Hakuta
Objective In oral health care, a refusal action can cause difficulties, and tactile hypersensitivity (TH) may be a contributing factor. People with TH of the face and mouth clench their jaws. Despite numerous reports on TH among children with disabilities, reports on TH in the elderly who are under long-term care are scarce. The purpose of this study was to investigate TH among the elderly who are under long-term care.Methods We selected 80 residents (8 men and 72 women; mean age: 91.1±6.2y) in a Tokyo nursing home and investigated the presence of TH in them...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28958026/estimation-of-skeletal-muscle-mass-relative-to-adiposity-improves-prediction-of-physical-performance-and-incident-disability
#10
Joshua F Baker, Jin Long, Mary B Leonard, Tamara Harris, Matthew J Delmonico, Adam Santanasto, Suzanne Satterfield, Babette Zemel, David R Weber
Purpose: We assessed the discrimination of lean mass estimates that have been adjusted for adiposity for physical functioning deficits and prediction of incident disability. Methods: Included were 2,846 participants from the Health, Aging and Body Composition Study with available whole-body dual energy absorptiometry measures of appendicular lean mass index (ALMI, kg/m2) and fat mass index (FMI, kg/m2). Age-, sex-, and race-specific Z-Scores and T-Scores were determined by comparison to published reference ranges...
July 29, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28945886/long-term-follow-up-study-of-mri-guided-bilateral-anterior-capsulotomy-in-patients-with-refractory-anorexia-nervosa
#11
Wei Liu, Dianyou Li, Fafa Sun, Xiaoxiao Zhang, Tao Wang, Shikun Zhan, Yixin Pan, Peng Huang, Haiyan Jin, Yongchao Li, Bomin Sun
BACKGROUND: Anorexia nervosa (AN) is one of the most challenging psychiatric disorders to treat. The poor clinical outcomes warrant novel treatments for AN, especially in severe and persistent cases. OBJECTIVE: To explore the feasibility of magnetic resonance imaging-guided bilateral anterior capsulotomy in the treatment of refractory AN. METHODS: Seventy-four patients diagnosed with refractory AN who underwent capsulotomy completed this 3-yr follow-up study...
August 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28943849/an-intention-driven-semi-autonomous-intelligent-robotic-system-for-drinking
#12
Zhijun Zhang, Yongqian Huang, Siyuan Chen, Jun Qu, Xin Pan, Tianyou Yu, Yuanqing Li
In this study, an intention-driven semi-autonomous intelligent robotic (ID-SIR) system is designed and developed to assist the severely disabled patients to live independently. The system mainly consists of a non-invasive brain-machine interface (BMI) subsystem, a robot manipulator and a visual detection and localization subsystem. Different from most of the existing systems remotely controlled by joystick, head- or eye tracking, the proposed ID-SIR system directly acquires the intention from users' brain. Compared with the state-of-art system only working for a specific object in a fixed place, the designed ID-SIR system can grasp any desired object in a random place chosen by a user and deliver it to his/her mouth automatically...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/28900454/the-effect-of-alpha-lipoic-acid-supplementation-on-anthropometric-indices-and-food-intake-in-patients-who-experienced-stroke-a-randomized-double-blind-placebo-controlled-clinical-trial
#13
Vida Mohammadi, Fariborz Khorvash, Awat Feizi, Gholamreza Askari
BACKGROUND: Stroke as a devastating condition is a major cause of death worldwide. It is accountable for long-term disability with high personal and social cost in adults. Alpha-lipoic acid (ALA) is an eight-carbon, sulfur-containing compound with antioxidant properties which reduces body weight, changes other anthropometric indices, and regulates food intake by suppressing appetite and increasing metabolism This study was designed to evaluate the possible effects of ALA supplementation on anthropometric indices and dietary intake in patients with stroke...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28898445/characterizing-adults-with-type-2-diabetes-mellitus-and-intellectual-disability-outcomes-of-a-case-finding-study
#14
L D Bryant, A M Russell, R E A Walwyn, A J Farrin, A Wright-Hughes, E H Graham, D Nagi, A Stansfield, J Birtwistle, S Meer, R A Ajjan, A O House
AIMS: To report the results of a case-finding study conducted during a feasibility trial of a supported self-management intervention for adults with mild to moderate intellectual disability and Type 2 diabetes mellitus, and to characterize the study sample in terms of diabetes control, health, and access to diabetes management services and support. METHODS: We conducted a cross-sectional case-finding study in the UK (March 2013 to June 2015), which recruited participants mainly through primary care settings...
September 12, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28894644/anthropometric-physical-function-and-general-health-markers-of-masters-athletes-a-cross-sectional-study
#15
Samantha Fien, Mike Climstein, Clodagh Quilter, Georgina Buckley, Timothy Henwood, Josie Grigg, Justin W L Keogh
Once the general decline in muscle mass, muscle strength and physical performance falls below specific thresholds, the middle aged or older adult will be diagnosed as having sarcopenia (a loss of skeletal muscle mass and strength). Sarcopenia contributes to a range of adverse events in older age including disability, hospitalisation, institutionalisation and falls. One potentially relevant but understudied population for sarcopenia researchers would be Masters athletes. Masters sport is becoming more common as it allows athletes (typically 40 years and older) the opportunity to participate in individual and/or team sports against individuals of similar age...
2017: PeerJ
https://www.readbyqxmd.com/read/28893573/measurement-of-nutritional-status-using-body-mass-index-waist-to-hip-ratio-and-waist-circumference-to-predict-treatment-outcome-in-females-and-males-with-acute-first-ever-ischemic-stroke
#16
Jan Paweł Bembenek, Michał Karlinski, Maciej Niewada, Iwona Kurkowska-Jastrzębska, Anna Członkowska
BACKGROUND: We aimed to investigate whether increased waist-to-hip ratio (WHR), waist circumference (WC), or improper body mass index (BMI) may differently predict short-term outcomes in females and males with first-ever acute ischemic stroke. METHODS: This was a retrospective study of consecutive patients (1109 females and 939 males) admitted for first-ever ischemic stroke between 2003 and 2015. Data were collected in a detailed hospital stroke registry. BMI of 18...
September 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28880236/sedentary-and-physical-activity-patterns-in-adults-with-intellectual-disability
#17
Guillermo R Oviedo, Noémie Travier, Myriam Guerra-Balic
Little is known about the patterns of sedentary time (ST) and physical activity (PA) levels throughout the week among adults and older adults with Intellectual Disability (ID). We analyzed ST and PA patterns of adults and older adults with ID. Forty-two adults and 42 older adults with mild to severe ID participated in this study. Height and weight were obtained to calculate Body Mass Index (BMI). Body fat and fat-free mass percentages were also obtained. Patterns of PA levels and ST were assessed with GT3X Actigraph accelerometers...
September 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28865035/effect-of-zoledronic-acid-on-lumbar-spinal-fusion-in-osteoporotic-patients
#18
Qirui Ding, Jian Chen, Jin Fan, Qingqing Li, Guoyong Yin, Lipeng Yu
PURPOSE: To investigate the effect of zoledronic acid (ZA) on lumbar spinal fusion in patients with osteoporosis. METHODS: This retrospective study includes 94 osteoporotic patients suffering from lumbar degenerative diseases or lumbar fracture who underwent lumbar spinal fusion in our institution from January 2013 to August 2014. They were divided into ZA group and control group according to whether the patient received ZA infusion or not. The patients in ZA group were given 5 mg intravenous ZA at the 3rd-5th days after operation...
September 1, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28852354/popliteal-baker-s-cysts-in-the-setting-of-primary-knee-arthroplasty
#19
Josef N Tofte, Andrew J Holte, Nicolas Noiseux
BACKGROUND: Popliteal (Baker's) Cysts are rare complications of knee arthroplasty. Enlargement, irritation, or rupture of the cyst can lead to significant pain, tightness, and tenderness. The literature regarding popliteal cysts occurring following knee arthroplasty is limited and does not report prevalence, natural history, and treatment of popliteal cyst in the setting of knee arthroplasty. METHODS: Following Institutional Review Board approval, 2,025 primary total and partial knee arthroplasties by four surgeons at one institution from 2011-2016 were reviewed for occurrence of popliteal cysts...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28846633/strawberries-improve-pain-and-inflammation-in-obese-adults-with-radiographic-evidence-of-knee-osteoarthritis
#20
Jace Schell, R Hal Scofield, James R Barrett, Biji T Kurien, Nancy Betts, Timothy J Lyons, Yan Daniel Zhao, Arpita Basu
Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key player, causing inflammation, pain, impaired joint function, and reduced quality of life. Dietary polyphenols and other bioactive compounds in berries, curcumin, and tea have shown effects in ameliorating pain and inflammation in OA, but few clinical studies have been reported. The purpose of the present study was to examine the effects of dietary strawberries on pain, markers of inflammation, and quality of life indicators in obese adults with OA of the knee...
August 28, 2017: Nutrients
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