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https://www.readbyqxmd.com/read/27909900/obesity-and-colorectal-cancer
#1
Carmen Jochem, Michael Leitzmann
There is strong evidence that modifiable lifestyle factors such as obesity play a key role in colorectal carcinogenesis. Epidemiologic data have consistently reported a positive association between obesity and colorectal cancer. The relative risk associated with general obesity (as assessed by BMI) is higher in men than in women and for cancer of the colon than for cancer of the rectum. Abdominal obesity (as assessed by waist circumference (WC) or waist-to-hip ratio) is associated with an increased risk of colorectal cancer in both sexes, with stronger associations for cancer of the colon than for cancer of the rectum...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909781/the-ability-of-low-magnitude-mechanical-signals-to-normalize-bone-turnover-in-adolescents-hospitalized-for-anorexia-nervosa
#2
A D DiVasta, H A Feldman, C T Rubin, J S Gallagher, N Stokes, D P Kiel, B D Snyder, C M Gordon
: We sought to determine whether low-magnitude mechanical stimulation (LMMS) normalizes bone turnover among adolescents hospitalized for anorexia nervosa (AN). Brief, daily LMMS prevents the decline in bone turnover typically seen during bed rest in AN. LMMS may have application for patients with AN in the inpatient setting to protect bone health. INTRODUCTION: Malnourished adolescents with AN requiring medical hospitalization are at high risk for rapid reduction in skeletal quality...
December 1, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27909377/association-between-body-composition-and-sport-injury-in-canadian-adolescents
#3
Allison M Ezzat, Amy Schneeberg, Mieke Koehoorn, Carolyn A Emery
Purpose: To examine the association between overweight or obesity and sport injury in a population-based sample of Canadian adolescents. Methods: Cross-sectional analyses were performed using the Canadian Community Health Survey (2009-2010), a nationally representative sample (n=12,407) of adolescents aged 12-19 years. Body composition was quantified using BMI, grouping participants into healthy weight, overweight, or obese. The outcome of interest was acute or repetitive strain injury sustained during sport in the previous year...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27905124/assessment-of-early-atherosclerosis-and-left-ventricular-dysfunction-in-children-with-21-hydroxylase-deficiency
#4
Rahmi Özdemir, Hüseyin Anil Korkmaz, Mehmet Küçük, Cem Karadeniz, Timur Meşe, Behzat Özkan
AIM: We analysed 25 children with 21-hydroxylase deficiency who received glucocorticoid and/or mineralocorticoid treatment for at least 12 months to determine the effects of the disease and its treatment on vascular structures and ventricular function. METHODS: Twenty-five patients with 21-hydroxylase-deficient congenital adrenal hyperplasia (CAH) and 25 control subjects were enrolled into this observational, cross-sectional study. The patients were investigated in terms of fasting blood glucose and insulin; fasting serum lipid profile; serum 17-hydroxyprogesterone; dehydroepiandrosterone sulphate; androstenedione; and adrenocorticotropic hormone...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27903346/-effect-of-snow-sports-on-knee-cartilage-maturation-in-children-and-adolescent-with-mri-quantitative-analysis-zhang
#5
B T Zhang, L Liu, J Zheng, Y M Dai, S N Yu, G F Liu, L Liu
Objective: To evaluate the effect of snow sports to the knee cartilage maturation of children and adolescent with quantitative analysis of 3.0 T MRI. Methods: Twenty children and adolescent who underwent snow sports training more than 6 months (11 males and 9 females) were recruited and named with sports group, and twenty children and adolescent who live regularly without any exercise (10 males and 10 females) were recruited as control group from June 2014 to June 2015.Each group was divided into subgroups according to their gender...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27901289/the-influence-of-physical-characteristics-on-the-resting-energy-expenditure-of-youth-a-meta-analysis
#6
REVIEW
Stephen D Herrmann, Robert G McMurray, Youngdeok Kim, Erik A Willis, Minsoo Kang, Thomas McCurdy
OBJECTIVE: To examine the literature on resting energy expenditure (REE) of youth and determine the influence of age, sex, BMI, and body composition on REE. METHODS: A literature search was conducted using PubMed, BIOSIS Previews, NTIS, EMBASE, MEDLINE, and Pascal databases for studies with data on resting metabolic rate, REE, resting oxygen uptake (or VO2 ) in healthy children, youth, or adolescents (age = 1-18 years). Over 200 publications were identified; sixty-one publications met criteria and were included in the meta-analyses, resulting in 142 study population estimates (totaling 5,397 youth) of REE...
November 30, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27901183/utility-of-body-mass-index-waist-circumference-and-waist-to-height-ratio-as-screening-tools-for-hyperglycemia-in-young-people
#7
Teresa Maria Bianchini de Quadros, Alex Pinheiro Gordia, Jorge Mota, Luciana Rodrigues Silva
Objectives: To evaluate the ability of BMI, WC and WHtR to discriminate hyperglycemia in young people, and to determine whether there is an increase in the accuracy with the addition of WC and/or WHtR to BMI. Subjects and methods: A cross-sectional study was conducted on 1,139 schoolchildren aged 6 to 17 years from Northeastern Brazil. Body weight, height, WC and fasting glucose levels were measured, and the BMI and WHtR were calculated. The presence of hyperglycemia was defined as a fasting glucose level ≥ 100 mg/dL...
November 24, 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27899001/drug-interventions-for-the-treatment-of-obesity-in-children-and-adolescents
#8
REVIEW
Emma Mead, Greg Atkinson, Bernd Richter, Maria-Inti Metzendorf, Louise Baur, Nicholas Finer, Eva Corpeleijn, Claire O'Malley, Louisa J Ells
BACKGROUND: Child and adolescent obesity has increased globally, and can be associated with significant short- and long-term health consequences. OBJECTIVES: To assess the efficacy of drug interventions for the treatment of obesity in children and adolescents. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, PubMed (subsets not available on Ovid), LILACS as well as the trial registers ICTRP (WHO) and ClinicalTrials.gov. Searches were undertaken from inception to March 2016...
November 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27898706/prediction-of-body-mass-index-using-concurrently-self-reported-or-previously-measured-height-and-weight
#9
Zhaohui Cui, June Stevens, Kimberly P Truesdale, Donglin Zeng, Simone French, Penny Gordon-Larsen
OBJECTIVE: To compare alternative models for the imputation of BMIM (measured weight in kilograms/measured height in meters squared) in a longitudinal study. METHODS: We used data from 11,008 adults examined at wave III (2001-2002) and wave IV (2007-2008) in the National Longitudinal Study of Adolescent to Adult Health. Participants were asked their height and weight before being measured. Equations to predict wave IV BMIM were developed in an 80% random subsample and evaluated in the remaining participants...
2016: PloS One
https://www.readbyqxmd.com/read/27895689/waist-to-height-ratio-as-a-screening-tool-for-obesity-and-cardiometabolic-risk
#10
REVIEW
Eun-Gyong Yoo
The waist-to-height ratio (WHtR), calculated by dividing the waist circumference (WC) by height, has recently gained attention as an anthropometric index for central adiposity. It is an easy-to-use and less age-dependent index to identify individuals with increased cardiometabolic risk. A WHtR cutoff of 0.5 can be used in different sex and ethnic groups and is generally accepted as a universal cutoff for central obesity in children (aged ≥6 years) and adults. However, the WHtR has not been validated in preschool children, and the routine use of WHtR in children under age 6 is not recommended...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27892411/metabolic-signatures-of-birthweight-in-18%C3%A2-288-adolescents-and-adults
#11
Peter Würtz, Qin Wang, Marjo Niironen, Tuulia Tynkkynen, Mika Tiainen, Fotios Drenos, Antti J Kangas, Pasi Soininen, Michael R Skilton, Kauko Heikkilä, Anneli Pouta, Mika Kähönen, Terho Lehtimäki, Richard J Rose, Eero Kajantie, Markus Perola, Jaakko Kaprio, Johan G Eriksson, Olli T Raitakari, Debbie A Lawlor, George Davey Smith, Marjo-Riitta Järvelin, Mika Ala-Korpela, Kirsi Auro
BACKGROUND: Lower birthweight is associated with increased susceptibility to cardiometabolic diseases in adulthood, but the underlying molecular pathways are incompletely understood. We examined associations of birthweight with a comprehensive metabolic profile measured in adolescents and adults. METHODS: High-throughput nuclear magnetic resonance metabolomics and biochemical assays were used to quantify 87 circulating metabolic measures in seven cohorts from Finland and the UK, comprising altogether 18 288 individuals (mean age 26 years, range 15-75)...
October 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27891415/urban-rural-comparison-of-anthropometry-and-menarcheal-status-of-adolescent-school-going-girls-of-jodhpur-rajasthan-india
#12
Shyama Choudhary, Satyendra Khichar, Dhanraj Dabi, Manish Parakh, Pawan K Dara, Poonam Parakh, Suyasha Vyas, Bindu Deopa
INTRODUCTION: Adolescence is the formative period of life. Poor adolescent health translates into poor maternal health leading to increased maternal morbidity with inter-generational consequences. AIM: To compare anthropometric, socio-demographic, menstrual and nutritional status of rural and urban adolescent school going girls of Western Rajasthan, India. MATERIALS AND METHODS: A cross-sectional comparative study was conducted in two rural schools and one urban school of Jodhpur region...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890980/bmi-is-a-better-indicator-of-cardiac-risk-factors-as-against-elevated-blood-pressure-in-apparently-healthy-female-adolescents-and-young-adult-students-results-from-a-cross-sectional-study-in-tripura
#13
Surajit Debnath
BACKGROUND: Anthropometric measures are used as indicators of elevated blood pressure, but reported to have variable sensitivity among populations. This study was undertaken to identify the better indicator of Cardiac-risk factors by statistical comparison of BMI, Waist circumference, and Waist to Height (WtHr) ratio in apparently healthy adolescents and young adult female students of Tripura. MATERIALS AND METHODS: A cross-sectional study was conducted in a resource limited setup on 210 apparently healthy female adolescents and young adult students in Tripura...
October 2016: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/27889912/insulin-like-growth-factor-1-and-metabolic-parameters-are-associated-with-non-alcoholic-fatty-liver-disease-in-obese-children-and-adolescents
#14
Shuang Liang, Xiangdeng Cheng, Yanyan Hu, Ruxin Song, Guimei Li
AIM: Few studies have investigated the relationship between paediatric non-alcoholic fatty liver disease (NAFLD) and insulin like growth factor 1 (IGF-1). This study, carried out from July 2013 to September 2015, aimed to fill the gap and added metabolic parameters to the analysis. METHODS: This was a cross-sectional study of 168 obese children and adolescents (84% male), divided into two groups based on the presence (n=90) or absence (n=78) of NAFLD. All participants underwent clinical examinations, anthropometric and laboratory examinations and liver ultrasonography...
November 27, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27885548/health-related-quality-of-life-in-long-term-survivors-of-acute-lymphoblastic-leukemia-in-childhood-and-adolescence
#15
T Nayiager, L Anderson, A Cranston, U Athale, R D Barr
PURPOSE: Children with acute lymphoblastic leukemia (ALL), the commonest form of cancer in this age group, suffer considerable morbidity during treatment, with the majority returning to good health soon after therapy has been completed, as reflected in health-related quality of life (HRQL). However, survivors are at risk of many adverse health outcomes later, including obesity, measured by body mass index (BMI), that is compounded by limited physical activity. This study examined the HRQL of long-term survivors of ALL and its relationship to BMI and physical activity...
November 24, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27882814/the-ao-pediatric-comprehensive-classification-of-long-bone-fractures-pccf-part-iii
#16
Laurent Audigé, Theddy Slongo, Nicolas Lutz, Andrea Blumenthal, Alexander Joeris
Background and purpose - The AO Pediatric Comprehensive Classification of Long Bone Fractures (PCCF) describes the localization and morphology of fractures, and considers severity in 2 categories: (1) simple, and (2) multifragmentary. We evaluated simple and multifragmentary fractures in a large consecutive cohort of children diagnosed with long bone fractures in Switzerland. Patients and methods - Children and adolescents treated for fractures between 2009 and 2011 at 2 tertiary pediatric surgery hospitals were retrospectively included...
November 24, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27881857/depressive-symptoms-body-composition-and-bone-mass-in-young-adults-a-prospective-cohort-study
#17
K Zhu, K Allen, J Mountain, S Lye, C Pennell, J P Walsh
BACKGROUND: An association between depression and obesity is well recognised, but longitudinal studies of depressive symptoms in adolescents as a predictor of body composition are lacking. OBJECTIVE: We examined depressive symptoms at age 14, 17 and 20 as predictors of lean, fat and bone mass at age 20 in a birth cohort. SUBJECTS/METHODS: In 1161 participants (569 females) in the Western Australia Pregnancy Cohort (Raine) Study, depressive symptoms were assessed using the Beck Depression Inventory for Youth at age 14 and 17, and the Depression, Anxiety and Stress Scale 21 at age 20...
November 24, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27880804/dietary-intake-and-eating-behaviours-of-obese-new-zealand-children-and-adolescents-enrolled-in-a-community-based-intervention-programme
#18
Yvonne C Anderson, Lisa E Wynter, Michelle S Butler, Cameron C Grant, Joanna M Stewart, Tami L Cave, Cervantée E K Wild, José G B Derraik, Wayne S Cutfield, Paul L Hofman
OBJECTIVES: The aim of this study was to describe dietary intake and eating behaviours of obese children and adolescents, and also to determine how these differ in Indigenous versus non-Indigenous children at enrolment in an obesity programme. METHODS: Baseline dietary intake and eating behaviour records were assessed from those enrolled in a clinical unblinded randomised controlled trial of a multi-disciplinary intervention. The setting was a community-based obesity programme in Taranaki, New Zealand...
2016: PloS One
https://www.readbyqxmd.com/read/27876543/in-utero-and-childhood-ddt-dde-pbde-and-pcbs-exposure-and-sex-hormones-in-adolescent-boys-the-chamacos-study
#19
Brenda Eskenazi, Stephen A Rauch, Rachel Tenerelli, Karen Huen, Nina T Holland, Robert H Lustig, Katherine Kogut, Asa Bradman, Andreas Sjodin, Kim G Harley
Dichlorodiphenyltrichloroethane (DDT), polybrominated diphenyl ether (PBDE) flame retardants, and polychlorinated biphenyls (PCBs) are believed to be endocrine-disrupting chemicals (EDCs) in humans and animals. The purpose of this study is to examine the relationship of in utero and childhood exposure to these purported EDCs and reproductive hormones in adolescent boys who participated in CHAMACOS, an ongoing birth cohort in California's Salinas Valley. We measured o,p'- and p,p'-DDT, p,p'- DDE, PBDEs and PCBs in serum collected from mothers during pregnancy or at delivery and from their sons at 9 years...
November 14, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27873431/hypoglycemia-is-common-in-children-with-cystic-fibrosis-and-seen-predominantly-in-females
#20
Belma Haliloglu, Yasemin Gokdemir, Zeynep Atay, Saygin Abali, Tulay Guran, Fazilet Karakoc, Refika Ersu, Bulent Karadag, Serap Turan, Abdullah Bereket
OBJECTIVE: To determine the prevalence of hypoglycemia in children and adolescents with cystic fibrosis (CF) in 2-hour oral glucose tolerance test (OGTT) and continuous glucose monitoring (CGM) under free-living conditions. RESEARCH DESIGN AND METHODS: Height, weight, body mass index (BMI), hemoglobin A1c (HbA1c), and Forced expiratory volume (FEV1%) were measured in children with CF (aged 5-18 years). Following OGTT, CGM was installed for 3 days. The total hypoglycemic and hyperglycemic time (%) during 3 days was measured...
November 22, 2016: Pediatric Diabetes
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