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https://www.readbyqxmd.com/read/28938788/cd4-t-cells-dominate-the-leukocyte-infiltration-response-initiated-by-intra-dermal-injection-of-phytohemagglutinin-into-growing-feathers-in-chickens
#1
K S Sullivan, G F Erf
Phytohemagglutinin (PHA) is commonly used to evaluate cell-mediated immunocompetence. In chickens, PHA is typically injected intra-dermally (i.d.) into the skin (e.g., wing web, wattle, or footpad), and the tissue swelling response is monitored, whereby the extent of tissue swelling positively relates to the individual's cell-mediated immune system capabilities. Although i.d. injected PHA was shown to stimulate mononuclear cell and basophil infiltration to the site of injection, reports on temporal, qualitative, and quantitative aspects of the local cutaneous PHA response are limited...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28938749/the-testicular-transcriptome-associated-with-spermatogonia-differentiation-initiated-by-gonadotrophin-stimulation-in-the-juvenile-rhesus-monkey-macaca-mulatta
#2
Suresh Ramaswamy, William H Walker, Paula Aliberti, Rahil Sethi, Gary R Marshall, Alyxzandria Smith, Seyedmehdi Nourashrafeddin, Alicia Belgorosky, Uma R Chandran, Mark P Hedger, Tony M Plant
STUDY QUESTION: What is the genetic landscape within the testis of the juvenile rhesus monkey (Macaca mulatta) that underlies the decision of undifferentiated spermatogonia to commit to a pathway of differentiation when puberty is induced prematurely by exogenous LH and FSH stimulation? SUMMARY ANSWER: Forty-eight hours of gonadotrophin stimulation of the juvenile monkey testis resulted in the appearance of differentiating B spermatogonia and the emergence of 1362 up-regulated and 225 down-regulated testicular mRNAs encoding a complex network of proteins ranging from enzymes regulating Leydig cell steroidogenesis to membrane receptors, and from juxtacrine and paracrine factors to transcriptional factors governing spermatogonial stem cell fate...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28938735/the-age-of-fathers-in-the-usa-is-rising-an-analysis-of-168-867-480-births-from-1972-to-2015
#3
Yash S Khandwala, Chiyuan A Zhang, Ying Lu, Michael L Eisenberg
STUDY QUESTION: How has the mean paternal age in the USA changed over the past 4 decades? SUMMARY ANSWER: The age at which men are fathering children in the USA has been increasing over time, although it varies by race, geographic region and paternal education level. WHAT IS KNOWN ALREADY: While the rise in mean maternal age and its implications for fertility, birth outcomes and public health have been well documented, little is known about paternal characteristics of births within the USA...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28938521/beneficial-health-applications-and-medicinal-values-of-pedicularis-plants-a-review
#4
REVIEW
Mohd Iqbal Yatoo, Umesh Dimri, Arumugam Gopalakrishnan, Kumaragurubaran Karthik, Marappan Gopi, Rekha Khandia, Mani Saminathan, Archana Saxena, Mahmoud Alagawany, Mayada Ragab Farag, Ashok Munjal, Kuldeep Dhama
Pedicularis plants (Orobanchaceae), popularly known as lousewort, are found in Asia, Europe, and North America, and have been used in Sowa-Rigpa, the Himalayan art of healing and a traditional system of medicine for treating various ailments in humans. A comprehensive compilation on this valuable medicinal plant is not available, however. The present extensive review provides insight into the salient medicinal properties of Pedicularis plants with respect to various health issues and diseases. Our previous studies on Pedicularis plants from the Changthang region of Ladakh (India) and research advances leading to new developments in this field have prompted this review...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28938517/green-tea-camellia-sinensis-and-l-theanine-medicinal-values-and-beneficial-applications-in-humans-a-comprehensive-review
#5
REVIEW
Muhammad Saeed, Muhammad Naveed, Muhammad Arif, Mohib Ullah Kakar, Robina Manzoor, Mohamed Ezzat Abd El-Hack, Mahmoud Alagawany, Ruchi Tiwari, Rekha Khandia, Ashok Munjal, Kumaragurubaran Karthik, Kuldeep Dhama, Hafiz M N Iqbal, Maryam Dadar, Chao Sun
Green tea (Camellia sinensis) is a famous herb, and its extract has been extensively used in traditional Chinese medicinal system. In this context, several studies have revealed its health benefits and medicinal potentialities for several ailments. With ever increasing scientific knowledge, search for safer, potential and novel type of health-related supplements quest, scientists are re-directing their research interests to explore natural resources i.e. medicinal herbs/plant derived compounds. Green tea consumption has gained a special attention and popularity in the modern era of changing lifestyle...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28938440/sex-differences-in-the-hormonal-and-metabolic-response-to-dietary-protein-dilution
#6
Karlton R Larson, Kimberly A Russo, Yanbin Fang, Niloufar Mohajerani, Michael L Goodson, Karen K Ryan
Consumption of a low-protein, high-carbohydrate diet induces a striking increase in circulating fibroblast growth factor-21 (FGF21), which is associated with improved cardiometabolic health and increased longevity. Increased lifespan during this dietary protein 'dilution' has been explained by resource-mediated trade-offs between reproduction and survival, such that fecundity is optimized at a greater relative intake of proteins:carbohydrates. The magnitude of this trade-off is thought to be sex-dependent. Here, we tested the hypothesis that metabolic responses to dietary protein dilution are likewise dependent on sex...
August 9, 2017: Endocrinology
https://www.readbyqxmd.com/read/28938403/change-in-weight-and-body-mass-index-associated-with-all-cause-mortality-in-korea-a-nationwide-longitudinal-study
#7
Yang-Hyun Kim, Seon Mee Kim, Kyung-do Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Won-Young Lee, Soon Jib Yoo
Background: Many studies have reported conflicting evidence on the association between weight change and mortality. Objective: We investigated the association between weight change and subsequent all-cause mortality, using a large-scale population-based cohort from the National Health Insurance System health checkup data between 2005 and 2015. Methods: A total of 11,524,763 subjects aged over 20 years were included. Weight was measured every two years and weight change over 4 years was divided into eight categories, from weight loss ≥15% to weight gain ≥20%, for every 5% of weight change...
August 24, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938270/bariatric-surgery-and-the-risk-of-cancer-in-a-large-multisite-cohort
#8
Daniel P Schauer, Heather Spencer Feigelson, Corinna Koebnick, Bette Caan, Sheila Weinmann, Anthony C Leonard, J David Powers, Panduranga R Yenumula, David E Arterburn
OBJECTIVE: To determine whether bariatric surgery is associated with a lower risk of cancer. BACKGROUND: Obesity is strongly associated with many types of cancer. Few studies have examined the relationship between bariatric surgery and cancer risk. METHODS: We conducted a retrospective cohort study of patients undergoing bariatric surgery between 2005 and 2012 with follow-up through 2014 using data from a large integrated health insurance and care delivery systems with 5 study sites...
September 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28938243/creating-a-learning-culture-for-medical-consortia-in-china
#9
Guozhong He, Zimin Chen
In China's recent health care reforms, both individuals and organizations have shown an ever-growing desire and demand for new knowledge and skills. A health care delivery system (HCDS) should explore new ways for creating a learning organization (LO) and should organically combine HCDS culture construction with the LO construction to build a cultural atmosphere that is conducive to the development of the LO. This article describes the implementation phase, characteristics, and realization strategy of an HCDS construction for the ultimate purpose of enhancing HCDS cohesion, solidarity, and sustainable development...
September 21, 2017: Health Care Manager
https://www.readbyqxmd.com/read/28938208/effects-of-process-operating-conditions-on-the-autotrophic-denitrification-of-nitrate-contaminated-groundwater-using-bioelectrochemical-systems
#10
D Cecconet, M Devecseri, A Callegari, A G Capodaglio
Nitrates have been detected in groundwater worldwide, and their presence can lead to serious groundwater use limitations, especially because of potential health problems. Amongst different options for their removal, bioelectrochemical systems (BESs) have achieved promising results; in particular, attention has raised on BES-driven autotrophic denitrification processes. In this work, the performance of a microbial electrolysis cell (MEC) for groundwater autotrophic denitrification, is assessed in different conditions of nitrate load, hydraulic retention time (HRT) and process configuration...
September 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28938204/natural-outdoor-environments-and-mental-health-stress-as-a-possible-mechanism
#11
Margarita Triguero-Mas, David Donaire-Gonzalez, Edmund Seto, Antònia Valentín, David Martínez, Graham Smith, Gemma Hurst, Glòria Carrasco-Turigas, Daniel Masterson, Magdalena van den Berg, Albert Ambròs, Tania Martínez-Íñiguez, Audrius Dedele, Naomi Ellis, Tomas Grazulevicius, Martin Voorsmit, Marta Cirach, Judith Cirac-Claveras, Wim Swart, Eddy Clasquin, Annemarie Ruijsbroek, Jolanda Maas, Michael Jerret, Regina Gražulevičienė, Hanneke Kruize, Christopher J Gidlow, Mark J Nieuwenhuijsen
INTRODUCTION: Better mental health has been associated with exposure to natural outdoor environments (NOE). However, comprehensive studies including several indicators of exposure and outcomes, potential effect modifiers and mediators are scarce. OBJECTIVES: We used novel, objective measures to explore the relationships between exposure to NOE (i.e. residential availability and contact) and different indicators of mental health, and possible modifiers and mediators...
September 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28938182/the-genetic-epidemiology-of-substance-use-disorder-a-review
#12
REVIEW
Elizabeth C Prom-Wormley, Jane Ebejer, Danielle M Dick, M Scott Bowers
BACKGROUND: Substance use disorder (SUD) remains a significant public health issue. A greater understanding of how genes and environment interact to regulate phenotypes comprising SUD will facilitate directed treatments and prevention. METHODS: The literature studying the neurobiological correlates of SUD with a focus on the genetic and environmental influences underlying these mechanisms was reviewed. Results from twin/family, human genetic association, gene-environment interaction, epigenetic literature, phenome-wide association studies are summarized for alcohol, nicotine, cannabinoids, cocaine, and opioids...
August 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28938156/removal-of-intra-and-extracellular-microcystin-by-submerged-ultrafiltration-uf-membrane-combined-with-coagulation-flocculation-and-powdered-activated-carbon-pac-adsorption
#13
Ayşe Büşra Şengül, Gamze Ersan, Neşe Tüfekçi
In this study, we investigated the performance of conventional (coagulation/flocculation→powdered activated carbon [PAC] adsorption) and advanced treatment (coagulation/flocculation→PAC adsorption→submerged ultrafiltration [UF] membrane) processes separately and sequentially for the removal of total (intra- and extracellular) microcystin. Results of the conventional treatment process demonstrated that coagulation/flocculation alone was not effective (up to 70%) for the removal of total microcystin, while the uptake of total microcystin was achieved up to 84% by PAC adsorption (PAC dose of 20mg/L)...
September 13, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28938046/the-value-that-infectious-diseases-physicians-bring-to-the-healthcare-system
#14
Daniel P McQuillen, Ann T MacIntyre
While a career in infectious diseases (ID) has always been challenging and exciting, recognition of the value that ID physicians provide to the healthcare system as a whole, over and above the value they provide to individual patients, has been poor in this system. In response to this disparity, the Infectious Diseases Society of America Clinical Affairs Committee has long endeavored to quantify the value of ID physicians to the system, which is challenging in part because of the many avenues through which they influence healthcare...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28938018/genome-wide-identification-of-bacterial-plant-colonization-genes
#15
Benjamin J Cole, Meghan E Feltcher, Robert J Waters, Kelly M Wetmore, Tatiana S Mucyn, Elizabeth M Ryan, Gaoyan Wang, Sabah Ul-Hasan, Meredith McDonald, Yasuo Yoshikuni, Rex R Malmstrom, Adam M Deutschbauer, Jeffery L Dangl, Axel Visel
Diverse soil-resident bacteria can contribute to plant growth and health, but the molecular mechanisms enabling them to effectively colonize their plant hosts remain poorly understood. We used randomly barcoded transposon mutagenesis sequencing (RB-TnSeq) in Pseudomonas simiae, a model root-colonizing bacterium, to establish a genome-wide map of bacterial genes required for colonization of the Arabidopsis thaliana root system. We identified 115 genes (2% of all P. simiae genes) with functions that are required for maximal competitive colonization of the root system...
September 22, 2017: PLoS Biology
https://www.readbyqxmd.com/read/28937986/household-costs-of-hospitalized-dengue-illness-in-semi-rural-thailand
#16
Yesim Tozan, Pitcha Ratanawong, Maquines Odhiambo Sewe, Annelies Wilder-Smith, Pattamaporn Kittayapong
BACKGROUND: Dengue-related illness is a leading cause of hospitalization and death in Thailand and other Southeast Asian countries, imposing a major economic burden on households, health systems, and governments. This study aims to assess the economic impact of hospitalized dengue cases on households in Chachoengsao province in eastern Thailand. METHODS: We conducted a prospective cost-of-illness study of hospitalized pediatric and adult dengue patients at three public hospitals...
September 22, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28937949/international-vision-care-issues-and-approaches
#17
Rohit C Khanna, Srinivas Marmamula, Gullapalli N Rao
Globally, 32.4 million individuals are blind and 191 million have moderate or severe visual impairment (MSVI); 80% of cases of blindness and MSVI are avoidable. However, great efforts are needed to tackle blindness and MSVI, as eye care in most places is delivered in isolation from and without significant integration with general health sectors. Success stories, including control of vitamin A deficiency, onchocerciasis, and trachoma, showed that global partnerships, multisectoral collaboration, public-private partnerships, corporate philanthropy, support from nongovernmental organizations-both local and international-and governments are responsible for the success of these programs...
September 15, 2017: Annual Review of Vision Science
https://www.readbyqxmd.com/read/28937935/the-impact-of-the-2006-massachusetts-health-care-reform-law-on-spine-surgery-patient-payer-mix-status-and-age
#18
Nicolas W Villelli, Hong Yan, Jian Zou, Nicholas M Barbaro
OBJECTIVE Several similarities exist between the Massachusetts health care reform law of 2006 and the Affordable Care Act (ACA). The authors' prior neurosurgical research showed a decrease in uninsured surgeries without a significant change in surgical volume after the Massachusetts reform. An analysis of the payer-mix status and the age of spine surgery patients, before and after the policy, should provide insight into the future impact of the ACA on spine surgery in the US. METHODS Using the Massachusetts State Inpatient Database and spine ICD-9-CM procedure codes, the authors obtained demographic information on patients undergoing spine surgery between 2001 and 2012...
September 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28937923/psychological-factors-in-chronic-edema-a-case-control-study
#19
Christine J Moffatt, Aimee Aubeeluck, Peter J Franks, Debra C Doherty, Peter Mortimer, Isabelle Quere
BACKGROUND: To examine psychological health and perceived social support in patients with chronic edema (CE). METHODS AND RESULTS: A random sample of 107 patients with CE was group matched for age and gender with 102 community controls. The cases had swelling of the arm (38%) and leg (61%) and midline swelling (14%). Cases were more likely to be single or divorced/separated (p = 0.041) and have reduced mobility (p < 0.001). They had significantly poorer overall health related quality of life (HRQoL), in particular physical functioning (p = 0...
September 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28937829/nonlinearity-coherence-and-complexity-biophysical-aspects-related-to-health-and-disease
#20
Alberto Foletti, Larissa Brizhik
Biological organisms are complex open dissipative systems whose dynamical stability is sustained due to the exchange of matter, energy and information. Dynamical stability occurs through a number of mechanisms that sustain efficient adaptive dynamics. Such properties of living matter can be the consequence of a self-consistent state of matter and electromagnetic field (EMF). Based on the soliton model of charge transport in redox processes, we describe a possible mechanism of the origin of endogenous EMF and coherence...
September 22, 2017: Electromagnetic Biology and Medicine
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