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Asymptomatic bacteriuria

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https://www.readbyqxmd.com/read/29149963/urinary-tract-infections-in-the-first-year-post-kidney-transplantation-potential-benefits-of-treating-asymptomatic-bacteriuria
#1
P Kotagiri, D Chembolli, J Ryan, P D Hughes, N D Toussaint
BACKGROUND: Urinary tract infections (UTIs) are the commonest infectious complication in kidney transplant recipients (KTRs). No recommendations exist regarding treatment of asymptomatic bacteriuria. We aimed to identify potential risk factors and microbiological profile for UTIs, the role of treatment of asymptomatic bacteriuria, and effects on graft outcomes of bacteriuria within the first year post-transplantation. METHODS: We performed a retrospective analysis of UTIs in KTRs transplanted between January 2012 and December 2013 in 2 transplantation centers...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29129031/evaluation-and-management-of-staphylococcus-aureus-bacteriuria-an-updated-review
#2
REVIEW
Stamatis Karakonstantis, Dimitra Kalemaki
BACKGROUND AND AIMS: There is little guidance regarding the evaluation and management of patients with Staphylococcus aureus bacteriuria (SABU). Here, we aimed to provide an up-to-date review of the literature. METHODS: We searched PubMed, Scopus, and clinical trial registries for articles evaluating the epidemiology of SABU, risk factors of SABU, the association of SABU with urinary tract infection, bacteremia and invasive S. aureus infections, and the management of patients with SABU...
November 11, 2017: Infection
https://www.readbyqxmd.com/read/29099028/post-stroke-bacteriuria-a-longitudinal-study-among-stroke-outpatients-and-inpatients-at-the-korle-bu-teaching-hospital-in-ghana
#3
Eric S Donkor, Samuel Darkwah, Albert Akpalu
Infections of the urinary tract constitute an important post-stroke complication but in Africa, little is known about such infections in relation to stroke patients. The aim of the study was to investigate the epidemiology of bacteriuria among stroke patients at the Korle-Bu Teaching Hospital (KBTH) in Ghana including the prevalence, incidence, risk factors and aetiological agents. This was a longitudinal study involving 55 outpatients and 16 inpatients of stroke from the physiotherapy clinic and stroke admission ward of KBTH respectively...
June 2, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29079155/urinary-tract-infection-and-asymptomatic-bacteriuria-in-older-adults
#4
REVIEW
Nicolas W Cortes-Penfield, Barbara W Trautner, Robin L P Jump
Urinary tract infections (UTIs) are a significant cause of morbidity among older adults. However, antibiotic prescriptions for clinically suspected UTIs are often inappropriate. Health care providers frequently struggle to differentiate UTI from asymptomatic bacteriuria, particularly in patients presenting with nonspecific symptoms. Patients with baseline cognitive impairments that limit history-taking can be particularly challenging. This article reviews the epidemiology and pathogenesis of UTI in older adults...
December 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29056969/clinical-characteristics-and-laboratory-identification-of-aerococcus-infections-an-australian-tertiary-centre-perspective
#5
Shanti Narayanasamy, Katherine King, Amanda Dennison, Denis W Spelman, Ar Kar Aung
Aerococci uncommonly cause urinary tract (UTI) and bloodstream infections (BSI). The clinical characteristics and laboratory identification rates of Aerococcus in the Australian context are unknown. A retrospective observational cohort study of patients with positive Aerococcus cultures between 2010 and 2015 was performed. Patients were analysed according to predefined "asymptomatic bacteriuria," "UTI," and "BSI" groups. Forty-seven [40 (85%) for urine and 7 (15%) for blood] isolates were identified [38% male, median age of 79 (IQR 62-85) years], with corresponding identification rates of 24...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/29037540/do-pregnant-women-with-asymptomatic-bacteriuria-need-treatment
#6
EDITORIAL
Wen-Hsun Chang, Chang-Chin Yeh, Peng-Hui Wang
No abstract text is available yet for this article.
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28973965/biofilm-formation-by-uropathogenic-escherichia-coli-is-favored-under-oxygen-conditions-that-mimic-the-bladder-environment
#7
Allison R Eberly, Kyle A Floyd, Connor J Beebout, Spencer J Colling, Madison J Fitzgerald, Charles W Stratton, Jonathan E Schmitz, Maria Hadjifrangiskou
One of the most common urologic problems afflicting millions of people worldwide is urinary tract infection (UTI). The severity of UTIs ranges from asymptomatic bacteriuria to acute cystitis, and in severe cases, pyelonephritis and urosepsis. The primary cause of UTIs is uropathogenic Escherichia coli (UPEC), for which current antibiotic therapies often fail. UPEC forms multicellular communities known as biofilms on urinary catheters, as well as on and within bladder epithelial cells. Biofilm formation protects UPEC from environmental conditions, antimicrobial therapy, and the host immune system...
September 30, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28973215/urinary-tract-infection
#8
REVIEW
Kalpana Gupta, Larissa Grigoryan, Barbara Trautner
Urinary tract infections (UTIs) are common in both inpatient and outpatient settings. This article provides an evidence-based, clinically relevant overview of management of UTIs, including screening, diagnosis, treatment, and prevention. Conditions covered include acute cystitis (both uncomplicated and complicated), catheter-associated UTI, and asymptomatic bacteriuria in both women and men.
October 3, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28970961/microorganisms-identified-in-the-maternal-bladder-discovery-of-the-maternal-bladder-microbiota
#9
Kristin M Jacobs, Krystal J Thomas-White, Evann E Hilt, Alan J Wolfe, Thaddeus P Waters
Objective  The objective of this study was to characterize the bladder microbiota in pregnancy. Methods  A prospective observational study of 51 pregnant women, admitted to a tertiary care hospital, who underwent straight catheterization urine collection or transurethral Foley catheter placement. 16S rRNA gene sequencing and enhanced quantitative urine culture assessed the maternal bladder microbiota with comparisons made to standard urine culture results. Results  Enhanced quantitative urine culture and 16S rRNA gene sequencing detected bacteria in the majority of participants...
July 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28954556/an-update-on-new-antibiotic-prophylaxis-and-treatment-for-urinary-tract-infections-in-children
#10
Jean Daniel Delbet, Mathie Lorrot, Tim Ulinski
This review focuses on the treatment of urinary tract infections (UTI) in children and in particular its recent changes. Areas covered: Acute pyelonephritis, acute cystitis and asymptomatic bacteriuria or asymptomatic infections have to be clearly distinguished. Prompt treatment is required in pyelonephritis and cystitis, but not in asymptomatic bacteriuria or infection, in order to avoid selection of more virulent strains. This concept should be considered even in immunocompromised or bedridden children. In case of pyelonephritis, there should be no delay in beginning the antibiotic treatment in order to decrease the risk of long term complication, such as renal scars...
October 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28947210/bacteriuria-is-not-associated-with-surgical-site-infection-in-patients-undergoing-cardiovascular-surgery
#11
Juan Carlos Duarte, Patricia Reyes, Diana Bermúdez, Juan Pablo Alzate, Javier Darío Maldonado, Jorge Alberto Cortés
BACKGROUND: Despite absence of evidence, in practice, asymptomatic bacteriuria is perceived as a risk factor for surgical site infection (SSI) among patients with cardiac surgery. We aimed to identify whether an association exists between the preoperative presence of asymptomatic bacteriuria or urinary tract infection and SSI in patients undergoing cardiovascular surgery. METHODS: This is an analytical study with a retrospective cohort of patients undergoing coronary revascularization or valve replacement surgery...
September 22, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28933357/risk-of-asymptomatic-bacteriuria-among-people-with-sickle-cell-disease-in-accra-ghana
#12
Eric S Donkor, Jonathan A Osei, Isaac Anim-Baidoo, Samuel Darkwah
Asymptomatic bacteriuria (ASB) is benign except in certain medical conditions such as pregnancy and immunosuppression. In Ghana, there are hardly any studies on urinary infections among sickle cell disease (SCD) patients, and the few studies carried out in Africa focused on pediatric SCD populations. The current study aimed to investigate the risk of ASB among SCD patients at a tertiary hospital in Ghana. This was a cross-sectional study involving 110 SCD patients and 110 age and sex matched healthy controls...
February 15, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/28894690/management-of-asymptomatic-bacteriuria-urinary-catheters-and-symptomatic-urinary-tract-infections-in-patients-undergoing-surgery-for-joint-replacement-a-position-paper-of-the-expert-group-infection-of-swissorthopaedics
#13
REVIEW
Parham Sendi, Olivier Borens, Peter Wahl, Martin Clauss, Ilker Uçkay
In this position paper, we review definitions related to this subject and the corresponding literature. Our recommendations include the following statements. Asymptomatic bacteriuria, asymptomatic leukocyturia, urine discolouration, odd smell or positive nitrite sediments are not an indication for antimicrobial treatment. Antimicrobial treatment of asymptomatic bacteriuria does not prevent periprosthetic joint infection, but is associated with adverse events, costs and antibiotic resistance development. Urine analyses or urine cultures in asymptomatic patients undergoing orthopaedic implants should be avoided...
2017: Journal of bone and joint infection
https://www.readbyqxmd.com/read/28884476/probiotics-for-preventing-urinary-tract-infection-in-people-with-neuropathic-bladder
#14
REVIEW
Swee-Ling Toh, Claire L Boswell-Ruys, Bon San B Lee, Judy M Simpson, Kate R Clezy
BACKGROUND: Neuropathic or neurogenic bladder describes a process of dysfunctional voiding as the result of injury in the brain, spinal cord or nerves innervating the bladder. People with neuropathic bladder, such as from spinal cord injury (SCI), are at significant risk of morbidity from urinary tract infections (UTI). Effective methods to prevent UTI in people with SCI have been sought for many years. Probiotics (micro-organisms that exert beneficial health effects in the host) have been recommended for bacterial interference of the urological tract to reduce colonisation by uropathogen and to manage the dual problems of infection and antibiotic resistance...
September 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28868940/vigilance-on-use-of-drugs-herbal-products-and-food-supplements-during-pregnancy-focus-on-fosfomycin
#15
C Mannucci, G Dante, M Miroddi, F Facchinetti, R D'Anna, A Santamaria, M C Lenti, A Vannacci, F Calapai, M Perone, G Migliardi, A Alibrandi, M Navarra, G Calapai
PURPOSE: Urinary tract infection (UTI) is defined as a common bacterial infection that can lead to significant morbidity such as stricture, fistula, abscess formation, bacteremia, sepsis, pyelonephritis, and kidney dysfunction with a mortality rates reported of 1% in men and 3% in women because of development of pyelonephritis. UTIs are more common in women and the 33% of them require antimicrobials treatment for at least one episode by the age of 24 years. UTIs are the most common infections observed during pregnancy and up to 30% of mothers with not treated asymptomatic bacteriuria may develop acute pyelonephritis which consequently can be associated to adverse maternal and fetal outcomes...
September 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28819490/maternofetal-outcome-of-asymptomatic-bacteriuria-among-pregnant-women-in-a-nigerian-teaching-hospital
#16
Kenneth Ebele Izuchukwu, Emmanuel Okwudili Oranu, Goddy Bassey, Ngozi Clare Orazulike
INTRODUCTION: Asymptomatic bacteriuria has been reported to be associated with adverse pregnancy outcome. This study sought to determine the prevalence and complications of asymptomatic bacteriuria amongst parturient in the University of Port Harcourt Teaching Hospital (UPTH). METHODS: The study was a prospective cohort study involving 220 eligible antenatal attendees. Urine culture and sensitivity was conducted for each participant and the fetomaternal outcome between affected and unaffected women were compared and p value <0...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28761863/management-of-urinary-tract-infections-in-patients-with-neurogenic-bladder-challenges-and-solutions
#17
REVIEW
Jürgen Pannek, Jens Wöllner
INTRODUCTION: Urinary tract infections (UTIs) are one of the most common morbidities in persons with neurogenic lower urinary tract dysfunction (NLUTD). They are associated with a significant morbidity and mortality, and they affect the quality of life of the affected patients. Diagnosis and treatment of UTI in this group of patients are challenging. In this review, the current strategies regarding diagnosis, treatment, and prevention are summarized. DIAGNOSTICS: it is important to correctly diagnose a UTI, as treatment of bacteriuria should strictly be avoided...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/28760710/the-impact-of-preoperative-bacteriuria-on-the-risk-of-periprosthetic-joint-infection-after-primary-knee-or-hip-replacement-a-retrospective-study-with-a-1-year-follow-up
#18
M Honkanen, E Jämsen, M Karppelin, R Huttunen, H Huhtala, A Eskelinen, J Syrjänen
OBJECTIVES: Patients who undergo elective joint replacement are traditionally screened and treated for preoperative bacteriuria to prevent periprosthetic joint infection (PJI). More recently, this practice has been questioned. The purpose of this study was to determine whether preoperative bacteriuria is associated with an increased risk of PJI. METHODS: Patients who had undergone a primary hip or knee replacement in a tertiary care hospital between September 2002 and December 2013 were identified from the hospital database (23 171 joint replacements, 10 200 hips, and 12 971 knees)...
July 29, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28754533/benefits-and-harms-of-treatment-of-asymptomatic-bacteriuria-a-systematic-review-and-meta-analysis-by-the-european-association-of-urology-urological-infection-guidelines-panel
#19
Bela Köves, Tommaso Cai, Rajan Veeratterapillay, Robert Pickard, Thomas Seisen, Thomas B Lam, Cathy Yuhong Yuan, Franck Bruyere, Florian Wagenlehner, Riccardo Bartoletti, Suzanne E Geerlings, Adrian Pilatz, Benjamin Pradere, Fabian Hofmann, Gernot Bonkat, Björn Wullt
People with asymptomatic bacteriuria (ABU) are often unnecessarily treated with antibiotics risking adverse effects and antimicrobial resistance. We performed a systematic review to determine any benefits and harms of treating ABU in particular patient groups. Relevant databases were searched and eligible trials were assessed for risk-of-bias and Grading of Recommendations, Assessment, Development and Education quality. Where possible, a meta-analysis of extracted data was performed or a narrative synthesis of the evidence was presented...
July 25, 2017: European Urology
https://www.readbyqxmd.com/read/28739824/epigenetic-mechanisms-regulate-innate-immunity-against-uropathogenic-and-commensal-like-escherichia-coli-in-the-surrogate-insect-model-galleria-mellonella
#20
Miriam Heitmueller, André Billion, Ulrich Dobrindt, Andreas Vilcinskas, Krishnendu Mukherjee
Innate-immunity-related genes in humans are activated during urinary tract infections (UTIs) caused by pathogenic strains of Escherichia coli but are suppressed by commensals. Epigenetic mechanisms play a pivotal role in the regulation of gene expression in response to environmental stimuli. To determine whether epigenetic mechanisms can explain the different behaviors of pathogenic and commensal bacteria, we infected larvae of the greater wax moth, Galleria mellonella, a widely used model insect host, with a uropathogenic E...
October 2017: Infection and Immunity
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