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Asymptomatic bacteriuria

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https://www.readbyqxmd.com/read/27906777/asymptomatic-bacteriuria-to-screen-or-not-to-screen-and-when-to-treat
#1
Tommaso Cai, Bela Koves, Truls E Bjerklund Johansen
PURPOSE OF REVIEW: Asymptomatic bacteriuria (ABU) is a common clinical condition that often leads to unnecessary treatment. The purpose of this review is to outline and evaluate the most recent literature on the management of ABU. RECENT FINDINGS: The role of ABU management has been evaluated in several patient subgroups: healthy patients without identified risk factors, pregnant women, postmenopausal women, women with recurrent UTI, patients with diabetes, elderly institutionalized patients, patients with renal transplants, patients with indwelling catheters and prior to surgery...
November 30, 2016: Current Opinion in Urology
https://www.readbyqxmd.com/read/27891369/the-diagnostic-value-of-urinalysis-in-hemodialysis-patients-with-fever-sepsis-or-suspected-urinary-tract-infection
#2
Katerina G Oikonomou, Adib Alhaddad
INTRODUCTION: The diagnostic validity of urinalysis in asymptomatic Hemodialysis (HD) patients is low and there is limited data on the diagnostic value of urinalysis in HD patients with fever, sepsis, or suspected Urinary Tract Infection (UTI). AIM: The aim of this study was to assess the sensitivity, specificity, positive and negative predictive value of pyuria, bacteriuria, Leukocyte Esterase (LE) and nitrite positivity in symptomatic, febrile or/and septic HD patients...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27866177/cranberries-for-preventing-recurrent-urinary-tract-infections-in-uncircumcised-boys
#3
Kong-Sang Wan, Chih-Kuang Liu, Wen-Kai Lee, Ming-Chung Ko, Che-Sheng Huang
Background • Highly concentrated cranberry juice has long been considered to have protective properties against urinary tract infections (UTIs), on the basis of its content of cranberry proanthocyanidins, with A-type interflavan bonds. Objective • This study intended to evaluate the benefits of a highly concentrated cranberry juice for the prevention of repeated episodes of UTI in uncircumcised boys. Design • The study was a randomized, controlled trial. Setting • The study took place at Taipei City Hospital, Renai and Zhongxing Branches (Taipei City, Taiwan)...
November 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27844263/the-resident-microflora-of-voided-midstream-urine-of-healthy-controls-standard-versus-expanded-urine-culture-protocols
#4
L Coorevits, S Heytens, J Boelens, G Claeys
The workup and interpretation of urine cultures is not always clear-cut, especially for midstream samples contaminated with commensals. Standard urine culture (SUC) protocols are designed in favor of growth of uropathogens at the expense of commensals. In selected clinical situations, however, it is essential to trace fastidious or new uropathogens by expanding the urine culture conditions (EUC). The aim of our study was to map the microflora in midstream urine specimens from healthy controls by means of EUC, in view of the interpretation of bacterial culture results in symptomatic patients...
November 14, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27833443/urine-interleukin-6-interleukin-8-and-transforming-growth-factor-%C3%AE-1-in-infants-with-urinary-tract-infection-and-asymptomatic-bacteriuria
#5
Grażyna Krzemień, Agnieszka Szmigielska, Agnieszka Turczyn, Małgorzata Pańczyk-Tomaszewska
INTRODUCTION: Urinary tract infection (UTI) occurs in 1.1% of girls and 1.4% of boys during the first year of life. Asymptomatic bacteriuria (ABU) is usually detected incidentally in 0.9% of girls and 2.5% of boys at this age. The aim of the study was to assess the usefulness of measurement of pro-inflammatory urine interleukin (IL)-6 and IL-8 concentrations and anti-inflammatory transforming growth factor β1 (TGF-β1) level in infants with febrile UTI, non-febrile UTI and ABU. MATERIAL AND METHODS: A total of 35 children, mean age 6...
2016: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/27806709/benefits-and-harms-of-screening-for-and-treatment-of-asymptomatic-bacteriuria-in-pregnancy-a-systematic-review
#6
Konstanze Angelescu, Barbara Nussbaumer-Streit, Wiebke Sieben, Fülöp Scheibler, Gerald Gartlehner
BACKGROUND: Most European and North American clinical practice guidelines recommend screening for asymptomatic bacteriuria (ASB) as a routine pregnancy test. Antibiotic treatment of ASB in pregnant women is supposed to reduce maternal upper urinary tract infections (upper UTIs) and preterm labour. However, most studies supporting the treatment of ASB were conducted in the 1950s to 1980s. Because of subsequent changes in treatment options for ASB and UTI, the applicability of findings from these studies has come into question...
November 2, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27780014/clinical-presentations-and-epidemiology-of-urinary-tract-infections
#7
Suzanne E Geerlings
Urinary tract infection (UTI) is one of the most common bacterial infections, and the incidence in women is much higher than in men. The diagnosis of a UTI can be made based on a combination of symptoms and a positive urine analysis or culture. Most UTIs are uncomplicated UTIs, defined as cystitis in a woman who is not pregnant, is not immunocompromised, has no anatomical and functional abnormalities of the urogenital tract, and does not exhibit signs of tissue invasion and systemic infection. All UTIs that are not uncomplicated are considered to be complicated UTIs...
October 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/27777649/genome-sequences-and-annotation-of-two-urinary-isolates-of-e-coli
#8
Travis K Price, Arya Mehrtash, Laurynas Kalesinskas, Kema Malki, Evann E Hilt, Catherine Putonti, Alan J Wolfe
The genus Escherichia includes pathogens and commensals. Bladder infections (cystitis) result most often from colonization of the bladder by uropathogenic E. coli strains. In contrast, a poorly defined condition called asymptomatic bacteriuria results from colonization of the bladder with E. coli strains without symptoms. As part of an on-going attempt to identify and characterize the newly discovered female urinary microbiota, we report the genome sequences and annotation of two urinary isolates of E. coli: one (E78) was isolated from a female patient who self-reported cystitis; the other (E75) was isolated from a female patient who reported that she did not have symptoms of cystitis...
2016: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/27773650/is-pre-operative-assessment-and-treatment-of-asymptomatic-bacteriuria-necessary-for-reducing-the-risk-of-post-operative-symptomatic-urinary-tract-infections-after-urological-surgical-procedures
#9
Tommaso Cai, Paolo Verze, Alessandro Palmieri, Mauro Gacci, Paolo Lanzafame, Gianni Malossini, Gabriella Nesi, Gernot Bonkat, Florian M E Wagenlehner, Vincenzo Mirone, Riccardo Bartoletti, Truls E Bjerklund Johansen
OBJECTIVES: To evaluate whether it is always necessary to test for the presence of asymptomatic bacteriuria (AB) in patients undergoing urological surgical procedures and if present, to treat AB with antimicrobial prophylaxis. METHODS: All patients who underwent urological surgical procedures from December 2008 to October 2013 in a tertiary referral urological center were considered for this study. All patients received antimicrobial prophylaxis in line with European Association of Urology (EAU) guidelines on urological infections...
October 20, 2016: Urology
https://www.readbyqxmd.com/read/27765580/comparison-of-different-antibiotic-protocols-for-asymptomatic-bacteriuria-in-patients-with-neurogenic-bladder-treated-with-botulinum-toxin-a
#10
Ana Claudia Paradella, André Ferraz de Arruda Musegante, Carlos Brites
Intravesical botulinum toxin A (BoNTA) injection has been widely used for the treatment of detrusor overactivity in patients with neurogenic bladder due to spinal cord injury who do not respond to conventional treatment. There is no consensus about antibiotic prophylaxis for this procedure. We conducted a retrospective analysis of medical records of adult patients with spinal cord injury who underwent detrusor BoNTA injection between January of 2007 and December of 2013 in a rehabilitation hospital. Occurrence of symptomatic urinary tract infection (UTI) was assessed in 3 groups in accordance with their use of antibiotics (prophylactic dosage, 3 days, more than 3 days) for the treatment of asymptomatic bacteriuria...
October 18, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27755605/correction-the-prevalence-of-asymptomatic-bacteriuria-in-iranian-pregnant-women-a-systematic-review-and-meta-analysis
#11
Mahin Ghafari, Vali Baigi, Zahra Cheraghi, Amin Doosti-Irani
[This corrects the article DOI: 10.1371/journal.pone.0158031.].
2016: PloS One
https://www.readbyqxmd.com/read/27697086/infection-prevention-and-antimicrobial-stewardship-knowledge-for-selected-infections-among-nursing-home-personnel
#12
Barbara W Trautner, M Todd Greene, Sarah L Krein, Heidi L Wald, Sanjay Saint, Andrew J Rolle, Sara McNamara, Barbara S Edson, Lona Mody
OBJECTIVE To assess knowledge about infection prevention among nursing home personnel and identify gaps potentially addressable through a quality improvement collaborative. DESIGN Baseline knowledge assessment of catheter-associated urinary tract infection, asymptomatic bacteriuria, antimicrobial stewardship, and general infection prevention practices for healthcare-associated infections. SETTING Nursing homes across 14 states participating in the national "Agency for Healthcare Research and Quality Safety Program for Long-Term Care: Healthcare-Associated Infections/Catheter-Associated Urinary Tract Infection...
October 4, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27617139/the-genetics-of-urinary-tract-infections-and-the-innate-defense-of-the-kidney-and-urinary-tract
#13
REVIEW
Ines Ambite, Gustav Rydstrom, Andrew L Schwaderer, David S Hains
The urinary tract is a sterile organ system. Urinary tract infections (UTIs) are common and often serious infections. Research has focused on uropathogen, environment, and host factors leading to UTI pathogenesis. A growing body of evidence exists implicating genetic factors that can contribute to UTI risks. In this review, we highlight genetic variations in aspects of the innate immune system critical to the host response to uropathogens. This overview includes genetic variations in pattern recognition receptor molecules, chemokines/cytokines, and neutrophil activation...
March 2016: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/27616488/antibiotic-prophylaxis-may-not-be-necessary-in-patients-with-asymptomatic-bacteriuria-undergoing-intradetrusor-onabotulinumtoxina-injections-for-neurogenic-detrusor-overactivity
#14
Lorenz Leitner, Ulla Sammer, Matthias Walter, Stephanie C Knüpfer, Marc P Schneider, Burkhardt Seifert, Jure Tornic, Ulrich Mehnert, Thomas M Kessler
Many of the patients undergoing intradetrusor onabotulinumtoxinA injections for refractory neurogenic detrusor overactivity (NDO) present with chronic bacteriuria. In these patients, antibiotic prophylaxis has been widely recommended since bacteriuria might impair treatment efficacy and cause urinary tract infections (UTI) but the evidence is limited. The aim of this study was to evaluate if an antibiotic prophylaxis is needed in patients with asymptomatic bacteriuria undergoing intradetrusor onabotulinumtoxinA injections...
September 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27609597/in-vitro-susceptibility-to-mecillinam-of-escherichia-coli-strains-isolated-from-the-urine-of-pregnant-women
#15
C Duployez, C Loiez, C Cattoen, D Descamps, F Wallet, A Vachée
OBJECTIVES: Pivmecillinam is a safe beta-lactam for use in pregnancy. It has been widely used for the treatment of lower urinary tract infections (UTIs) in the Nordic countries where its efficacy, minor impact on the microbiota, and low level of resistance among the Escherichia coli strains have been proven. However, susceptibility data related to E. coli involved in asymptomatic bacteriuria and lower UTIs in pregnant women is lacking. We aimed to support the 2015 recommendations issued by the French Infectious Diseases Society (SPILF) on gestational UTI, with a particular focus on pivmecillinam...
December 2016: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/27573368/impact-of-an-antimicrobial-stewardship-care-bundle-to-improve-the-management-of-patients-with-suspected-or-confirmed-urinary-tract-infection
#16
Curtis D Collins, Jared J Kabara, Sarah M Michienzi, Anurag N Malani
Implementation of an antimicrobial stewardship program bundle for urinary tract infections among 92 patients led to a higher rate of discontinuation of therapy for asymptomatic bacteriuria (52.4% vs 12.5%; P =.004), more appropriate durations of therapy (88.7% vs 63.6%; P =.001), and significantly higher overall bundle compliance (75% vs 38.2%; P < .001). Infect Control Hosp Epidemiol 2016;1499-1501.
December 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27547467/antibiotic-prophylaxis-and-its-appropriate-timing-for-urological-surgical-procedures-in-patients-with-asymptomatic-bacteriuria-a-systematic-review
#17
REVIEW
Jorge A Ramos, Diego F Salinas, Johanna Osorio, Alberto Ruano-Ravina
OBJECTIVE: To review the existing literature on when and how to treat patients with asymptomatic bacteriuria (AB) who undergo urological surgery, as uncertainty about this issue persists. METHODS: A systematic review was conducted to compare the different timing of administration of antibiotic prophylaxis in patients with AB undergoing urological surgery. We used predefined inclusion and exclusion criteria, and we also developed a specific quality scale to assess the quality of the papers included...
September 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27530532/a-multi-center-controlled-randomized-open-label-clinical-study-of-levofloxacin-for-preventing-infection-during-the-perioperative-period-of-ultrasound-guided-transrectal-prostate-biopsy
#18
L-D Qiao, S Chen, X-F Wang, W-M Yang, Y-J Niu, C-Z Kong, W Tang, X-F Gao, B-K Shi, Y-Q Na, X-D Zhang, J-Y Wang, Y Zhang, Z Chen
By comparing the safety and efficacy of 500 mg of oral levofloxacin for 3 days with those of intravenous antibiotics for 3 days in the prevention of infectious complications of ultrasound-guided transrectal prostate biopsy (TPB), we provided a safe and cost-effective infection preventive protocol for TPB in China. A total of 801 patients with indications for TPB in 12 centers were randomized into two groups from October 2011 to December 2015. Patients in the test group (n = 392) took 500 mg of oral levofloxacin for 3 days...
November 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27514605/genitourinary-infections-in-diabetic-patients-in-the-new-era-of-diabetes-therapy-with-sodium-glucose-cotransporter-2-inhibitors
#19
M Rizzi, R Trevisan
AIMS: To review prevalence and significance of urinary tract (UTI) and genital infections (GI) in diabetes and the effects of sodium glucose cotransporter 2 (SGLT-2) inhibitors on these complications. DATA SYNTHESIS: The prevalence of asymptomatic bacteriuria (ASB) is 2-3 times higher in diabetic than in non-diabetic women. The treatment of ASB has no impact on the development of UTIs and/or a decline in renal function. Therefore, there is no indication for screening for and/or treatment of ASB...
July 12, 2016: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/27500352/accuracy-of-onsite-tests-to-detect-asymptomatic-bacteriuria-in-pregnancy-a-systematic-review-and-meta-analysis
#20
Ewelina Rogozińska, Sandra Formina, Javier Zamora, Luciano Mignini, Khalid S Khan
OBJECTIVE: To estimate the accuracy of onsite tests to detect asymptomatic bacteriuria among pregnant women. DATA SOURCES: We searched MEDLINE, EMBASE, Web of Science, Scopus, and Latin-American Literature from inception until June 2015 without language restrictions. The ClinicalTrials.gov register database was screened to identify any recently completed studies. METHODS OF STUDY SELECTION: Two independent reviewers selected studies that recruited asymptomatic pregnant women to evaluate the accuracy of onsite tests in detecting the presence of bacteria in the urine using urine culture as a reference standard...
September 2016: Obstetrics and Gynecology
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