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https://www.readbyqxmd.com/read/28453745/percentage-of-mesenchymal-stem-cells-in-high-grade-glioma-tumor-samples-correlates-with-patient-survival
#1
Tal Shahar, Uri Rozovski, Kenneth R Hess, Anwar Hossain, Joy Gumin, Feng Gao, Gregory N Fuller, Lindsey Goodman, Erik P Sulman, Frederick F Lang
Background.: Human mesenchymal stem cells (hMSCs) have been shown to reside as stromal cells in human gliomas as glioma-associated hMSCs (GA-hMSCs), but their biological role remains unclear. Because recent evidence indicates that GA-hMSCs drive tumor cell proliferation and stemness, we hypothesized that a higher percentage of GA-hMSCs in tumors predicts poor patient prognosis. Method.: We determined the percentage of cells coexpressing GA-hMSC markers CD105+/CD73+/CD90+ from patients with newly diagnosed high-grade glioma and analyzed the association between this percentage and overall survival (OS) in 3 independent cohorts: fresh surgical glioblastoma specimens (cohort 1, N = 9), cultured tumor specimens at passage 3 (cohort 2, N = 28), and The Cancer Genome Atlas (TCGA) database...
May 1, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28453559/evaluation-of-the-reproducibility-of-amplicon-sequencing-with-illumina-miseq-platform
#2
Chongqing Wen, Liyou Wu, Yujia Qin, Joy D Van Nostrand, Daliang Ning, Bo Sun, Kai Xue, Feifei Liu, Ye Deng, Yuting Liang, Jizhong Zhou
Illumina's MiSeq has become the dominant platform for gene amplicon sequencing in microbial ecology studies; however, various technical concerns, such as reproducibility, still exist. To assess reproducibility, 16S rRNA gene amplicons from 18 soil samples of a reciprocal transplantation experiment were sequenced on an Illumina MiSeq. The V4 region of 16S rRNA gene from each sample was sequenced in triplicate with each replicate having a unique barcode. The average OTU overlap, without considering sequence abundance, at a rarefaction level of 10,323 sequences was 33...
2017: PloS One
https://www.readbyqxmd.com/read/28453348/the-effect-of-therapeutic-whirlpool-and-hot-packs-on-hand-volume-during-rehabilitation-after-distal-radius-fracture-a-blinded-randomized-controlled-trial
#3
Mike Szekeres, Joy C MacDermid, Trevor Birmingham, Ruby Grewal, Emily Lalone
BACKGROUND: Edema is a possibility with all heating modalities due to the increase in local blood flow caused by vasodilation. Despite the frequent application of superficial heat modalities, their relative effect on hand volume has not been determined for the upper extremity. The objective of this study was to compare the immediate effects of hot packs and whirlpool on hand volume for patients with distal radius fracture (DRF) and to determine whether any changes in volume between these modalities were still present 30 minutes after heat application...
May 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28448426/orexin-receptor-antagonism-in-painful-diabetic-neuropathy-a-phase-2-trial-with-filorexant
#4
W Joseph Herring, Joy Y Ge, Saheeda Jackson, Christopher Assaid, Kathryn M Connor, David Michelson
OBJECTIVES: To evaluate whether orexin receptor antagonism with filorexant provides pain relief in patients with painful diabetic neuropathy (PDN). METHODS: In this double-blind, placebo-controlled, enriched-enrollment, randomized-withdrawal proof-of-concept study, patients with PDN (aged 18-75 y) entered a 2-week, single-blind active run-in period with filorexant 10 mg nightly, before randomization 1:1 to placebo or filorexant in a 2-week, double-blind treatment period...
April 26, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28446699/polydomy-enhances-foraging-performance-in-ant-colonies
#5
N Stroeymeyt, P Joye, L Keller
Collective foraging confers benefits in terms of reduced predation risk and access to social information, but it heightens local competition when resources are limited. In social insects, resource limitation has been suggested as a possible cause for the typical decrease in per capita productivity observed with increasing colony size, a phenomenon known as Michener's paradox. Polydomy (distribution of a colony's brood and workers across multiple nests) is believed to help circumvent this paradox through its positive effect on foraging efficiency, but there is still little supporting evidence for this hypothesis...
April 26, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28445431/assessing-diabetes-and-factors-associated-with-foregoing-medical-care-among-persons-with-diabetes-disparities-facing-american-indian-alaska-native-black-hispanic-low-income-and-southern-adults-in-the-u-s-2011-2015
#6
Samuel D Towne, Jane Bolin, Alva Ferdinand, Emily Joy Nicklett, Matthew Lee Smith, Marcia G Ory
Objective: Identify individual- and place-based factors associated with diagnosed diabetes and forgone medical care among those diagnosed with diabetes. Background: Diabetes affects millions of individuals globally. In the U.S. alone the prevalence rate of diagnosed diabetes has more than doubled over the past 20 years (4.2% in 1994 to 10% in 2014). Methods: The Behavioral Risk Factor Surveillance System (2011-2015) was used to identify factors associated with self-reported diabetes diagnoses (ever diagnosed) among U...
April 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28444952/similarity-in-volatile-communities-leads-to-increased-herbivory-and-greater-tropical-forest-diversity
#7
Tara Joy Massad, Marcílio Martins de Moraes, Casey Philbin, Celso Oliveira, Gerardo Cebrian Torrejon, Lydia Fumiko Yamaguchi, Christopher S Jeffrey, Lee A Dyer, Lora A Richards, Massuo Jorge Kato
A longstanding paradigm in ecology is that there are positive associations between herbivore diversity, specialization, and plant species diversity, with a focus on taxonomic diversity. However, phytochemical diversity is also an informative metric, as insect herbivores interact with host-plants not as taxonomic entities, but as sources of nutrients, primary metabolites, and mixtures of attractant and repellant chemicals. The present research examines herbivore responses to phytochemical diversity measured as volatile similarity in the tropical genus Piper...
April 26, 2017: Ecology
https://www.readbyqxmd.com/read/28444554/relationships-between-environmental-factors-and-participation-in-adults-with-traumatic-brain-injury-stroke-and-spinal-cord-injury-a-cross-sectional-multi-center-study
#8
Alex W K Wong, Sheryl Ng, Jessica Dashner, M Carolyn Baum, Joy Hammel, Susan Magasi, Jin-Shei Lai, Noelle E Carlozzi, David S Tulsky, Ana Miskovic, Arielle Goldsmith, Allen W Heinemann
PURPOSE: To develop and evaluate a model of environmental factors-participation relationships for persons with traumatic brain injury (TBI), stroke, and spinal cord injury (SCI), and test whether this model differed across three diagnostic groups, as well as other demographic and clinical characteristics. METHODS: A cross-sectional observational study included 545 community-dwelling adults with neurological disorders (TBI = 166; stroke = 189; SCI = 190) recruited at three academic medical centers...
April 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28437572/nearly-a-decade-long-repeatable-seasonal-diversity-patterns-of-bacterioplankton-communities-in-the-eutrophic-lake-donghu-wuhan-china
#9
Qingyun Yan, James C Stegen, Yuhe Yu, Ye Deng, Xinghao Li, Shu Wu, LilI Dai, Xiang Zhang, Jinjin Li, Chun Wang, Jiajia Ni, Xuemei Li, Hongjuan Hu, Fanshu Xiao, Weisong Feng, Daliang Ning, Zhili H E, Joy D Van Nostrand, Liyou Wu, Jizhong Zhou
Uncovering which environmental factors govern community diversity patterns and how ecological processes drive community turnover are key questions related to understand the community assembly. However, the ecological mechanisms regulating long-term variations of bacterioplankton communities in lake ecosystems remains poorly understood. Here we present nearly a decade-long study of bacterioplankton communities from the eutrophic Lake Donghu (Wuhan, China) using 16S rRNA gene amplicon sequencing with MiSeq platform...
April 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28437188/further-characterization-of-the-mitigation-of-radiation-lethality-by-protective-wounding
#10
Joseph R Dynlacht, Joy Garrett, Rebecca Joel, Katharina Lane, Marc S Mendonca, Christie M Orschell
There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological terrorist attack. The ideal countermeasure should be effective when administered after exposure, and over a wide range of absorbed doses. We have previously shown that the administration of a subcutaneous incision of a defined length, if administered within minutes after irradiation, protected young adult female C57BL/6 mice against radiation-induced lethality, and increased survival after total-body exposure to an LD50/30 X-ray dose from 50% to over 90%...
April 24, 2017: Radiation Research
https://www.readbyqxmd.com/read/28437140/a-proven-alternative-to-compression-bandaging
#11
Joy Tickle, Liz Ovens, Kirsten Mahoney, Sharon Hunt, Elaine Harris, Laura Hodgman
No abstract text is available yet for this article.
April 1, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28436287/positive-affect-and-physical-activity-testing-effects-on-goal-setting-activation-prioritisation-and-attainment
#12
David S Cameron, Emma J Bertenshaw, Paschal Sheeran
OBJECTIVE: The present research tested whether incidental positive affect promotes pursuit of physical activity goals. Four key features of goal pursuit were examined - setting physical activity goals (Study 1), goal activation (Study 2), and goal prioritization and goal attainment (Study 3). DESIGN: Participants (Ns = 80, 81, and 59, in Studies 1-3, respectively) were randomized to positive affect (joy, hope) or neutral affect (control) conditions in each study...
April 23, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28435666/health-care-and-social-media-what-patients-really-understand
#13
Kyle Hoedebecke, Lindsey Beaman, Joy Mugambi, Sanam Shah, Marwa Mohasseb, Cheyanne Vetter, Kim Yu, Irini Gergianaki, Emily Couvillon
Background: Low health literacy is associated with decreased patient compliance and worse outcomes - with clinicians increasingly relying on printed materials to lower such risks. Yet, many of these documents exceed recommended comprehension levels. Furthermore, patients look increasingly to social media (SoMe) to answer healthcare questions. The character limits built into Twitter encourage users to publish small quantities of text, which are more accessible to patients with low health literacy. The present authors hypothesize that SoMe posts are written at lower grade levels than traditional medical sources, improving patient health literacy...
2017: F1000Research
https://www.readbyqxmd.com/read/28435467/ultrasound-elastography-review-of-techniques-and-clinical-applications
#14
REVIEW
Rosa M S Sigrist, Joy Liau, Ahmed El Kaffas, Maria Cristina Chammas, Juergen K Willmann
Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies to yield qualitative and quantitative information that can be used for diagnostic purposes. Measurements are acquired in specialized imaging modes that can detect tissue stiffness in response to an applied mechanical force (compression or shear wave). Ultrasound-based methods are of particular interest due to its many inherent advantages, such as wide availability including at the bedside and relatively low cost...
2017: Theranostics
https://www.readbyqxmd.com/read/28430189/warming-enhances-old-organic-carbon-decomposition-through-altering-functional-microbial-communities
#15
Lei Cheng, Naifang Zhang, Mengting Yuan, Jing Xiao, Yujia Qin, Ye Deng, Qichao Tu, Kai Xue, Joy D Van Nostrand, Liyou Wu, Zhili He, Xuhui Zhou, Mary Beth Leigh, Konstantinos T Konstantinidis, Edward Ag Schuur, Yiqi Luo, James M Tiedje, Jizhong Zhou
Soil organic matter (SOM) stocks contain nearly three times as much carbon (C) as the atmosphere and changes in soil C stocks may have a major impact on future atmospheric carbon dioxide concentrations and climate. Over the past two decades, much research has been devoted to examining the influence of warming on SOM decomposition in topsoil. Most SOM, however, is old and stored in subsoil. The fate of subsoil SOM under future warming remains highly uncertain. Here, by combining a long-term field warming experiment and a meta-analysis study, we showed that warming significantly increased SOM decomposition in subsoil...
April 21, 2017: ISME Journal
https://www.readbyqxmd.com/read/28428924/a-case-report-of-salmonella-muenchen-enteritis-causing-rhabdomyolysis-and-myocarditis-in-a-previously-healthy-26-year-old-man
#16
Will Chapple, Jon Martell, Joy S Wilson, Don T Matsuura
This case report examines an unusual presentation of a non-typhoidal Salmonella serovar with limited prevalence in the literature. This is the first case report to associate specifically the Salmonella muenchen serovar with rhabdomyolysis and myocarditis. This case report reviews the diagnostic criteria for myocarditis and explores the diagnostic dilemma of troponin elevation in the setting of rhabdomyolysis. It demonstrates that Salmonella muenchen has the ability to present in a broad range of individuals with complications extending beyond classical gastrointestinal symptoms...
April 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28428610/joy-harrild-award-for-young-dentists-launched
#17
(no author information available yet)
No abstract text is available yet for this article.
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28426991/clinical-usefulness-of-18-f-fdg-pet-ct-for-initial-staging-and-assessment-of-treatment-efficacy-in-patients-with-lymph-node-tuberculosis
#18
Nicolas Lefebvre, Xavier Argemi, Nicolas Meyer, Joy Mootien, Nawal Douiri, Stefania Sferrazza-Mandala, Frédéric Schramm, Noëlle Weingertner, Daniel Christmann, Yves Hansmann, Alessio Imperiale
INTRODUCTION: Few studies have evaluated the promising role of (18)F-fluoro-2-deoxy-D-glucose positron emission tomography (PET) and PET/computed tomography FDG PET/CT in evaluating and monitoring treatment response in patients with lymph node tuberculosis (LNTB). The aim of this clinical investigation was to assess the clinical usefulness of FDG PET/CT for initial tuberculosis staging and to determine the prognostic value of the decrease of (18)F-FDG uptake during antibiotic treatment in LNTB patients...
April 8, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28426505/foreword
#19
Joy L Hawkins
No abstract text is available yet for this article.
June 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28426364/patterns-of-mood-and-personality-factors-and-associations-with-sti-hiv-related-drug-and-sex-risk-among-african-american-male-inmates
#20
Joy D Scheidell, Carl W Lejuez, Carol E Golin, Adaora A Adimora, David A Wohl, Larry D Keen, Michael Hammond, Selena Judon-Monk, Maria R Khan
BACKGROUND: Research on the association between antisocial personality disorder (ASPD) with comorbid mental disorders and sexually transmitted infection (STI)/HIV risk among inmates is scant despite the high prevalence of psychopathology and of STI/HIV in this population. METHODS: We used baseline data from Project DISRUPT, a cohort study conducted among incarcerated African American men (n = 207), to measure associations between ASPD and STI/HIV risk. We also conducted latent class analyses (LCAs) to identify subgroups defined by ASPD with comorbid stress, depression, and borderline personality disorder symptoms and measured associations between latent class membership and STI/HIV risk...
June 7, 2017: Substance Use & Misuse
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