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https://www.readbyqxmd.com/read/29331850/attentional-biases-in-patients-suffering-from-unipolar-depression-results-of-a-dot-probe-task-investigation
#1
Wolfgang Trapp, Christoph Kalzendorf, Corinna Baum, Göran Hajak, Stefan Lautenbacher
Cognitive models of depression emphasize the relevance of cognitive biases for development, onset and maintenance of major depressive disorder (MDD). Attentional biases consisting of increased attention to negative, mood congruent stimuli and reduced attention to positive, mood-incongruent stimuli are postulated but have rarely been tested for early attentional processing. Furthermore, the role of concurrent depressive mood as a moderating factor has not been studied to date. Participants comprised 30 patients suffering from MDD and 30 healthy control subjects...
January 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29330239/one-year-of-family-physicians-observations-on-working-with-medical-scribes
#2
Amelia Sattler, Tracy Rydel, Cathina Nguyen, Steven Lin
PURPOSE: The immense clerical burden felt by physicians is one of the leading causes of burnout. Scribes are increasingly being used to help alleviate this burden, yet few published studies investigate how scribes affect physicians' daily work, attitudes and behaviors, and relationships with patients and the workplace. METHODS: Using a longitudinal observational design, data were collected, over 1 year, from 4 physicians working with 2 scribes at a single academic family medicine practice...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29328002/dexamethasone-mediated-oncogenicity-in-vitro-and-in-an-animal-model-of-glioblastoma
#3
Markus M Luedi, Sanjay K Singh, Jennifer C Mosley, Islam S A Hassan, Masumeh Hatami, Joy Gumin, Lukas Andereggen, Erik P Sulman, Frederick F Lang, Frank Stueber, Gregory N Fuller, Rivka R Colen, Pascal O Zinn
OBJECTIVE Dexamethasone, a known regulator of mesenchymal programming in glioblastoma (GBM), is routinely used to manage edema in GBM patients. Dexamethasone also activates the expression of genes, such as CEBPB, in GBM stem cells (GSCs). However, the drug's impact on invasion, proliferation, and angiogenesis in GBM remains unclear. To determine whether dexamethasone induces invasion, proliferation, and angiogenesis in GBM, the authors investigated the drug's impact in vitro, in vivo, and in clinical information derived from The Cancer Genome Atlas (TCGA) cohort...
January 12, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29327312/examining-the-prospective-relationship-between-pre-disaster-respiratory-sinus-arrhythmia-and-post-disaster-posttraumatic-stress-disorder-symptoms-in-children
#4
Amy J Mikolajewski, Michael S Scheeringa
Previous studies have examined the concurrent relationship between posttraumatic stress disorder (PTSD) and a range of psychophysiological variables, including respiratory sinus arrhythmia (RSA). However, there is a lack of research examining the prospective development of trauma symptomatology, and the directionality of the association between RSA level and PTSD has yet to be determined. The current study is the first prospective study to examine whether RSA level and RSA reactivity are risk factors for PTSD symptoms in children...
January 12, 2018: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/29325468/does-enhanced-support-for-offenders-effectively-reduce-custodial-violence-and-disruption-an-evaluation-of-the-enhanced-support-service-pilot
#5
Jake Camp, Kerry Joy, Mark Freestone
This study aimed to examine the effectiveness of The Enhanced Support Service (ESS) pilot in reducing custodial violence and disruption, and the associated costs, by observing the behavioural change of the 35 service users who participated in ESS intervention within its first 22 months of operation. Frequencies of recorded incidents of aggressive behaviours, self-harming behaviours, noncompliance, and positive behaviours were counted from routine administrative systems using a coding structure developed in previous studies...
January 1, 2018: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29324811/scale-up-of-kenya-s-national-hiv-viral-load-program-findings-and-lessons-learned
#6
Matilu Mwau, Catherine Akinyi Syeunda, Maureen Adhiambo, Priska Bwana, Lucy Kithinji, Joy Mwende, Laura Oyiengo, Martin Sirengo, Caroline E Boeke
OBJECTIVES: Kenya is one of the first African countries to scale up a national HIV viral load monitoring program. We sought to assess program scale up using the national database and identify areas for systems strengthening. METHODS: Data from January 2012 to March 2016 were extracted from Kenya's national viral load database. Characteristics of 1,108,356 tests were assessed over time, including reason for testing, turnaround times, test results, treatment regimens, and socio-demographic information...
2018: PloS One
https://www.readbyqxmd.com/read/29324636/simple-sequence-repeat-ssr-genetic-linkage-map-of-d-genome-diploid-cotton-derived-from-an-interspecific-cross-between-gossypium-davidsonii-and-gossypium-klotzschianum
#7
Joy Nyangasi Kirungu, Yanfeng Deng, Xiaoyan Cai, Richard Odongo Magwanga, Zhongli Zhou, Xingxing Wang, Yuhong Wang, Zhenmei Zhang, Kunbo Wang, Fang Liu
The challenge in tetraploid cotton cultivars is the narrow genetic base and therefore, the bottleneck is how to obtain interspecific hybrids and introduce the germplasm directly from wild cotton to elite cultivars. Construction of genetic maps has provided insight into understanding the genome structure, interrelationships between organisms in relation to evolution, and discovery of genes that carry important agronomic traits in plants. In this study, we generated an interspecific hybrid between two wild diploid cottons, Gossypium davidsonii and Gossypium klotzschianum, and genotyped 188 F2:3 populations in order to develop a genetic map...
January 11, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29323796/treatment-of-chronic-rhinosinusitis-with-dornase-alfa-in-patients-with-cystic-fibrosis-a-systematic-review
#8
Gopi B Shah, Linde De Keyzer, Joy A Russell, Ashleigh Halderman
BACKGROUND: A major component of sputum in cystic fibrosis (CF) patients is polymerized DNA, a byproduct of degraded neutrophils. Dornase alfa (dornase) selectively cleaves extracellular DNA and reduces the viscosity of sputum. It improves mucociliary clearance and pulmonary function. The benefit of dornase on CF-associated sinusitis is less clear. Therefore, the objective of this study was to systematically review the use of dornase on chronic rhinosinusitis (CRS) in CF patients. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was followed for this systematic review...
January 11, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29323121/the-endogenous-grp78-interactome-in-human-head-and-neck-cancers-a-deterministic-role-of-cell-surface-grp78-in-cancer-stemness
#9
Hsin-Ying Chen, Joseph Tung-Chieh Chang, Kun-Yi Chien, Yun-Shien Lee, Guo-Rung You, Ann-Joy Cheng
Cell surface glucose regulated protein 78 (GRP78), an endoplasmic reticulum (ER) chaperone, was suggested to be a cancer stem cell marker, but the influence of this molecule on cancer stemness is poorly characterized. In this study, we developed a mass spectrometry platform to detect the endogenous interactome of GRP78 and investigated its role in cancer stemness. The interactome results showed that cell surface GRP78 associates with multiple molecules. The influence of cell population heterogeneity of head and neck cancer cell lines (OECM1, FaDu, and BM2) according to the cell surface expression levels of GRP78 and the GRP78 interactome protein, Progranulin, was investigated...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29321377/development-of-an-airway-mucus-defect-in-the-cystic-fibrosis-rat
#10
Susan E Birket, Joy M Davis, Courtney M Fernandez, Katherine L Tuggle, Ashley M Oden, Kengyeh K Chu, Guillermo J Tearney, Michelle V Fanucchi, Eric J Sorscher, Steven M Rowe
The mechanisms underlying the development and natural progression of the airway mucus defect in cystic fibrosis (CF) remain largely unclear. New animal models of CF, coupled with imaging using micro-optical coherence tomography, can lead to insights regarding these questions. The Cftr-/- (KO) rat allows for longitudinal examination of the development and progression of airway mucus abnormalities. The KO rat exhibits decreased periciliary depth, hyperacidic pH, and increased mucus solid content percentage; however, the transport rates and viscoelastic properties of the mucus are unaffected until the KO rat ages...
January 11, 2018: JCI Insight
https://www.readbyqxmd.com/read/29320806/experiences-of-living-kidney-donors-during-the-donation-process
#11
Hanne Agerskov, Claus Bistrup, Mette S Ludvigsen, Birthe D Pedersen
BACKGROUND: The shortage of organs from deceased donors has led to more living donation. Furthermore, immunological developments have made it possible to perform kidney transplantation despite preformed antibodies against the donor organ. This has led to a broader recruitment base of living donors. OBJECTIVE: The objective was to investigate experiences and considerations on becoming, and during the process of being, a living kidney donor. MATERIALS AND METHODS: Interviews and participant observation were conducted before, during and after the donation...
January 10, 2018: Journal of Renal Care
https://www.readbyqxmd.com/read/29320325/diseases-involving-the-central-bronchi-multidetector-ct-for-detection-characterization-and-differential-diagnosis
#12
Marie-Michele Theriault, Kathleen Eddy, Joy N Borgaonkar, Judith L Babar, Daria Manos
No abstract text is available yet for this article.
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29320304/complications-of-sling-surgery-for-stress-urinary-incontinence-among-female-military-beneficiaries
#13
David L Howard, Andrea McGlynn, Joy A Greer
BACKGROUND: Prior studies of complications after sling surgery excluded the large number of women in military treatment facilities (MTFs). OBJECTIVE: To characterize the postoperative complication rates after sling surgery for Stress urinary incontinence (SUI) within MTFs in the United States. MATERIALS AND METHODS: Retrospective cohort study of women aged 18 and older, with SUI, and who underwent either an outpatient or inpatient mid-urethral sling placement for SUI in any MTF in the United States between January 1, 2011 and December 31, 2012...
January 10, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29319373/clinical-learning-spaces-crucibles-for-practice-development-in-physiotherapy-clinical-education
#14
Narelle Patton, Joy Higgs, Megan Smith
This paper, through a deep examination of clinical workplaces as learning spaces, uses a holistic interpretation of clinical education and offers a practice development crucible metaphor as a useful way to deepen how clinical education can be conceptualized. An in-depth conceptualization of clinical education is needed if educators are able to develop wise educational practice and optimize the time students spend in clinical learning settings. The research reported here was undertaken in the qualitative paradigm guided by philosophical hermeneutics...
January 10, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29318754/coordination-of-bilateral-tooth-replacement-in-the-juvenile-gecko-is-continuous-with-in-ovo-patterning
#15
Theresa M Grieco, Joy M Richman
We performed a test of how function impacts a genetically programmed process that continues into postnatal life. Using the dentition of the polyphyodont gecko as our model, tooth shedding was recorded longitudinally across the jaw. We compared two time periods: one in which teeth were patterned symmetrically in ovo and a later period when teeth were initiated post-hatching. By pairing shedding events on the right and left sides, we found the patterns of tooth loss are symmetrical and stable between periods, with only subtle deviations...
January 10, 2018: Evolution & Development
https://www.readbyqxmd.com/read/29318426/determining-procedures-for-simulation-based-training-in-radiology-a-nationwide-needs-assessment
#16
Leizl Joy Nayahangan, Kristina Rue Nielsen, Elisabeth Albrecht-Beste, Michael Bachmann Nielsen, Charlotte Paltved, Karen Gilboe Lindorff-Larsen, Bjørn Ulrik Nielsen, Lars Konge
OBJECTIVES: New training modalities such as simulation are widely accepted in radiology; however, development of effective simulation-based training programs is challenging. They are often unstructured and based on convenience or coincidence. The study objective was to perform a nationwide needs assessment to identify and prioritize technical procedures that should be included in a simulation-based curriculum. METHODS: A needs assessment using the Delphi method was completed among 91 key leaders in radiology...
January 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29317134/to-p-or-not-to-p-that-is-not-the-question
#17
EDITORIAL
Joy C MacDermid
No abstract text is available yet for this article.
January 6, 2018: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29316640/sub-chronic-toxicity-of-the-hydroethanolic-leaf-extract-of-telfairia-occidentalis-hook-f-cucurbitaceae-in-male-rats
#18
Abidemi J Akindele, Joy A Oladimeji-Salami, Ramon A Oyetola, Daniel D Osiagwu
Background: Due to its nutritional and medicinal values, the leaf of Telfairia occidentalis Hook f. (Cucurbitaceae) is consumed in different parts of Nigeria. Acute and sub-chronic toxicity of the hydroethanolic leaf extract of Telfairiaoccidentalis were investigated in this study. Methods: Sixty-four male rats were randomized into four different groups of 16 animals each and were separately administered 80, 400 and 2000 mg/kg T. occidentalis orally (p.o.) for 60 days. Animals were sacrificed and blood samples were collected for hematological and biochemical analyses...
January 6, 2018: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29316573/a-thing-of-beauty-is-a-joy-forever
#19
Markus K Heinemann
No abstract text is available yet for this article.
January 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29313828/resistive-switching-in-individual-zno-nanorods-delineating-the-ionic-current-by-photo-stimulation
#20
Kingshuk Bandopadhyay, Krishna Nand Prajapati, Joy Mitra
Resistive switching in nanostructured metal oxide semiconductors has been broadly understood to originate from the dynamics of its native point defects. Experimental results of switching observed in individual n-ZnO nanorods grown on a p-type polymer is presented along with an empirical model describing the underlying defect dynamics necessary to observe bi-polar switching. Selective photo excitation of electrons into the defect states delineates the incidence and role of an ionic current in the switching behavior...
January 9, 2018: Nanotechnology
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