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https://www.readbyqxmd.com/read/28454102/an-inverse-association-between-tea-consumption-and-colorectal-cancer-risk
#1
Yuetong Chen, Yuan Wu, Mulong Du, Haiyan Chu, Lingjun Zhu, Na Tong, Zhengdong Zhang, Meilin Wang, Dongying Gu, Jinfei Chen
It is well known that the tea extracts, mainly polyphenols as chemo-preventive elements, could act as cancer progression blockers. Although the association between tea consumption and colorectal cancer risk has been widely investigated, the results still remain inconsistent. We conducted a dose-response meta-analysis to evaluate their relationships by enrolling qualified 29 literatures. The summary odds ratio (OR) of colorectal cancer for the highest vs. lowest tea consumption was 0.93 with 0.87-1.00 of 95% confidence intervals (CIs) among all studies with modest heterogeneity (P = 0...
April 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454068/biochar-based-water-treatment-systems-as-a-potential-low-cost-and-sustainable-technology-for-clean-water-provision
#2
REVIEW
Willis Gwenzi, Nhamo Chaukura, Chicgoua Noubactep, Fungai N D Mukome
Approximately 600 million people lack access to safe drinking water, hence achieving Sustainable Development Goal 6 (Ensure availability and sustainable management of water and sanitation for all by 2030) calls for rapid translation of recent research into practical and frugal solutions within the remaining 13 years. Biochars, with excellent capacity to remove several contaminants from aqueous solutions, constitute an untapped technology for drinking water treatment. Biochar water treatment has several potential merits compared to existing low-cost methods (i...
April 25, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28454045/canadian-harm-reduction-policies-a-comparative-content-analysis-of-provincial-and-territorial-documents-2000-2015
#3
REVIEW
T Cameron Wild, Bernie Pauly, Lynne Belle-Isle, Walter Cavalieri, Richard Elliott, Carol Strike, Kenneth Tupper, Andrew Hathaway, Colleen Dell, Donald MacPherson, Caitlin Sinclair, Kamagaju Karekezi, Benjamin Tan, Elaine Hyshka
BACKGROUND: Access to harm reduction interventions among substance users across Canada is highly variable, and largely within the policy jurisdiction of the provinces and territories. This study systematically described variation in policy frameworks guiding harm reduction services among Canadian provinces and territories as part of the first national multimethod case study of harm reduction policy. METHODS: Systematic and purposive searches identified publicly-accessible policy texts guiding planning and organization of one or more of seven targeted harm reduction services: needle distribution, naloxone, supervised injection/consumption, low-threshold opioid substitution (or maintenance) treatment, buprenorphine/naloxone (suboxone), drug checking, and safer inhalation kits...
April 25, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28454035/occurrence-and-genetic-diversity-of-cryptosporidium-and-giardia-in-urban-wastewater-treatment-plants-in-north-eastern-spain
#4
Ana Ramo, Emilio Del Cacho, Caridad Sánchez-Acedo, Joaquín Quílez
This study was designed to investigate the presence and removal efficiency of Cryptosporidium and Giardia in wastewater treatment plants at the 20 most populated towns in Aragón (north-eastern Spain). Samples of influent and effluent wastewater and dewatered sewage sludge were collected seasonally from 23 plants and processed according to USEPA Method 1623. All samples from raw and treated wastewater tested positive for Giardia, at an average concentration of 3247±2039cysts/l and 50±28cysts/l, respectively...
April 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28454015/air-pollution-characteristics-and-health-risks-in-henan-province-china
#5
Fuzhen Shen, Xinlei Ge, Jianlin Hu, Dongyang Nie, Li Tian, Mindong Chen
Events of severe air pollution occurred frequently in China recently, thus understanding of the air pollution characteristics and its health risks is very important. In this work, we analyzed a two-year dataset (March 2014 - February 2016) including daily concentrations of six criteria pollutants (PM2.5, PM10, CO, SO2, NO2, and O3) from 18 cities in Henan province. Results reveal the serious air pollution status in Henan province, especially the northern part, and Zhengzhou is the city with the worst air quality...
April 25, 2017: Environmental Research
https://www.readbyqxmd.com/read/28454014/reduced-mouse-allergen-is-associated-with-epigenetic-changes-in-regulatory-genes-but-not-mouse-sensitization-in-asthmatic-children
#6
Rachel L Miller, Hanjie Zhang, Jacqueline Jezioro, Mariangels De Planell Saguer, Stephanie Lovinsky-Desir, Xinhua Liu, Matthew Perzanowski, Adnan Divjan, Wanda Phipatanakul, Elizabeth C Matsui
Chronic exposure to mouse allergen may contribute greatly to the inner-city asthma burden. We hypothesized that reducing mouse allergen exposure may modulate the immunopathology underlying symptomatic pediatric allergic asthma, and that this occurs through epigenetic regulation. To test this hypothesis, we studied a cohort of mouse sensitized, persistent asthmatic inner-city children undergoing mouse allergen-targeted integrated pest management (IPM) vs education in a randomized controlled intervention trial...
April 25, 2017: Environmental Research
https://www.readbyqxmd.com/read/28453863/use-of-a-geographic-information-system-to-assess-accessibility-to-health-facilities-providing-emergency-obstetric-and-newborn-care-in-bangladesh
#7
Mahbub E Chowdhury, Taposh K Biswas, Monjur Rahman, Kamal Pasha, Mollah A Hossain
OBJECTIVE: To use a geographic information system (GIS) to determine accessibility to health facilities for emergency obstetric and newborn care (EmONC) and compare coverage with that stipulated by UN guidelines (5 EmONC facilities per 500 000 individuals, ≥1 comprehensive). METHODS: A cross-sectional study was undertaken of all public facilities providing EmONC in 24 districts of Bangladesh from March to October 2012. Accessibility to each facility was assessed by applying GIS to estimate the proportion of catchment population (comprehensive 500 000; basic 100 000) able to reach the nearest facility within 2 hours and 1 hour of travel time, respectively, by existing road networks...
April 28, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28453718/cost-effectiveness-analysis-of-malaria-rapid-diagnostic-tests-for-appropriate-treatment-of-malaria-at-the-community-level-in-uganda
#8
Kristian S Hansen, Richard Ndyomugyenyi, Pascal Magnussen, Sham Lal, Siân E Clarke
In Sub-Saharan Africa, malaria remains a major cause of morbidity and mortality among children under 5, due to lack of access to prompt and appropriate diagnosis and treatment. Many countries have scaled-up community health workers (CHWs) as a strategy towards improving access. The present study was a cost-effectiveness analysis of the introduction of malaria rapid diagnostic tests (mRDTs) performed by CHWs in two areas of moderate-to-high and low malaria transmission in rural Uganda. CHWs were trained to perform mRDTs and treat children with artemisinin-based combination therapy (ACT) in the intervention arm while CHWs offered treatment based on presumptive diagnosis in the control arm...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453716/inflated-medicine-prices-in-vietnam-a-qualitative-study
#9
Tuan Anh Nguyen, Rosemary Knight, Andrea Mant, Husna Razee, Geoffrey Brooks, Thu Ha Dang, Elizabeth Ellen Roughead
One third of the world's population lacks regular access to essential medicines partly because of the high cost of medicines. In Vietnam, the cost to patients of medicines was 47 times the international reference price for originator brands and 11 times the price for generic equivalents in the public sector. In this article, we report the results of a qualitative study conducted to identify the principal reasons for inflated medicine prices in Vietnam.Between April 2008 and December 2009, 29 semi-structured interviews were conducted with staff from pharmaceutical companies, private pharmacies, the Ministry of Health, and the Ministry of Finance of Vietnam...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453712/use-of-performance-metrics-for-the-measurement-of-universal-coverage-for-maternal-care-in-mexico
#10
Edson Serván-Mori, David Contreras-Loya, Octavio Gomez-Dantés, Gustavo Nigenda, Sandra G Sosa-Rubí, Rafael Lozano
This study provides evidence for those working in the maternal health metrics and health system performance fields, as well as those interested in achieving universal and effective health care coverage. Based on the perspective of continuity of health care and applying quasi-experimental methods to analyse the cross-sectional 2009 National Demographic Dynamics Survey (n = 14 414 women), we estimated the middle-term effects of Mexico's new public health insurance scheme, Seguro Popular de Salud (SPS) (vs women without health insurance) on seven indicators related to maternal health care (according to official guidelines): (a) access to skilled antenatal care (ANC); (b) timely ANC; (c) frequent ANC; (d) adequate content of ANC; (e) institutional delivery; (f) postnatal consultation and (g) access to standardized comprehensive antenatal and postnatal care (or the intersection of the seven process indicators)...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453694/clinical-benefit-price-and-approval-characteristics-of-fda-approved-new-drugs-for-treating-advanced-solid-cancer-2000-2015
#11
A Vivot, J Jacot, J-D Zeitoun, P Ravaud, P Crequit, R Porcher
Background: Prices of anti-cancer drugs are skyrocking. We aimed to assess the clinical benefit of new drugs for treating advanced solid tumors at the time of their approval by the US Food and Drug Administration (FDA) and to search for a relation between price and clinical benefit of drugs. Materials and methods: We included all new molecular entities and new biologics for treating advanced solid cancer that were approved by the FDA between 2000 and 2015. The clinical benefit of drugs was graded based on FDA medical review of pivotal clinical trials using the 2016-updated of the American Society of Clinical Oncology Value Framework (ASCO-VF) and the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS)...
May 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28453666/inequalities-in-rural-communities-adapting-national-deprivation-indices-for-rural-settings
#12
D Fecht, A Jones, T Hill, T Lindfield, R Thomson, A L Hansell, R Shukla
Background: Deprivation indices have been widely used in healthcare research and planning in the United Kingdom. Existing indices, however, are dominated by characteristics of urban populations that may be less relevant in capturing the nature of rural deprivation. We explore if deprivation indices can be modified to make them more sensitive to displaying rural disadvantage in England. Methods: The analysis focussed on the 2011 Carstairs Index (Carstairs2011) and the 2010 English Index of Multiple Deprivation (IMD2010)...
April 27, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28453645/medicare-part-d-payments-for-topical-steroids-rising-costs-and-potential-savings
#13
Hannah Song, Adewole Adamson, Arash Mostaghimi
Importance: Rising pharmaceutical costs in the United States are an increasing source of financial burden for payers and patients. Although topical steroids are among the most commonly prescribed medications in dermatology, there are limited data on steroid-related spending and utilization. Objective: To characterize Medicare and patient out-of-pocket costs for topical steroids, and to model potential savings that could result from substitution of the cheapest topical steroid from the corresponding potency class...
April 28, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28453626/protocol-to-monitor-trade-agreement-food-related-aspects-the-fiji-case-study
#14
Amerita Ravuvu, Sharon Friel, Anne Marie Thow, Wendy Snowdon, Jillian Wate
Despite the growing rates of obesity and diet-related non-communicable diseases, globally, public health attention has only relatively recently turned to the links between trade agreements and the nutritional risks associated with it. Specific trade agreements appear to have played an influential role in the volume and types of foods entering different countries, yet there is currently no systematic and objective monitoring of trade agreements for their impacts on food environments. Recently, INFORMAS was set up to monitor and benchmark food environments, government policies and private sector actions within countries and globally...
April 26, 2017: Health Promotion International
https://www.readbyqxmd.com/read/28453610/the-future-of-uk-healthcare-problems-and-potential-solutions-to-a-system-in-crisis
#15
H E Montgomery, A Haines, N Marlow, G Pearson, M G Mythen, M P W Grocott, C Swanton
The UK's Health System is in crisis, central funding no longer keeping pace with demand. Traditional responses-spending more, seeking efficiency savings or invoking market forces-are not solutions. The health of our nation demands urgent delivery of a radical new model, negotiated openly between public, policymakers and healthcare professionals. Such a model could focus on disease prevention, modifying health behaviour and implementing change in public policy in fields traditionally considered unrelated to health such as transport, food and advertising...
April 27, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28453605/outlier-practice-patterns-in-mohs-micrographic-surgery-defining-the-problem-and-a-proposed-solution
#16
Aravind Krishnan, Tim Xu, Susan Hutfless, Angela Park, Thomas Stasko, Allison T Vidimos, Barry Leshin, Brett M Coldiron, Richard G Bennett, Victor J Marks, Rebecca Brandt, Martin A Makary, John G Albertini
Importance: Outlier physician practices in health care can represent a significant burden to patients and the health system. Objective: To study outlier physician practices in Mohs micrographic surgery (MMS) and the associated factors. Design, Setting, and Participants: This retrospective analysis of publicly available Medicare Part B claims data from January 2012 to December 2014 includes all physicians who received Medicare payments for MMS from any practice performing MMS on the head and neck, genitalia, hands, and feet region of Medicare Part B patients...
April 28, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28453591/-the-impact-of-tap-water-fluoridation-on-human-health
#17
Verena Romero, Frances J Norris, Juvenal A Ríos, Isel Cortés, Andrea González, Leonardo Gaete, Andrei N Tchernitchin
The purpose of this review is to describe the osteological, neurological, endocrine and dermatological effects of fluoride ingestion. Additional aims are to evaluate whether the Chilean tap water fluoridation program has had any impact on dental health, and analyze the basis for the Chilean elementary school milk fluoridation program, which is targeted at children living in places where tap water has a fluoride concentration less than 0.3 mg/L, without any artificial fluoridation process. We discuss the finding that both public measures have no direct or remarkable effect on dental health, since topical dental hygiene products are the main and most effective contributors to the prevention of dental decay...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28453503/preface
#18
Cynthia Villarreal-Garza, Andrea Castro-Sanchez, Alfredo Ulloa-Aguirre
Breast cancer (BC) is the most frequently diagnosed malignancy in young women and is the leading cause of cancer-related mortality in this age group. This issue represents a major public health problem in developing countries, where the incidence of BC is rapidly increasing and where young women represent a higher proportion of the total BC patient population compared to developed countries. In Latin America, BC among women aged 40 years or less accounts for up to 11% of new BC cases and 7% of all BC deaths...
March 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28453429/anti-microbial-coating-innovations-to-prevent-infectious-diseases-amici-cost-action-ca15114
#19
Colum P Dunne, Minna M Keinänen-Toivola, Anne Kahru, Birgit Teunissen, Hulya Olmez, Isabel Gouveia, Luis Melo, Kazimierz Murzyn, Martina Modic, Merja Ahonen, Pete Askew, Theofilos Papadopoulos, Christian Adlhart, Francy R L Crijns
Worldwide, millions of patients are affected annually by healthcare-associated infection (HCAI), impacting up to 80,000 patients in European Hospitals on any given day. This represents not only public health risk, but also an economic burden. Complementing routine hand hygiene practices, cleaning and disinfection, antimicrobial coatings hold promise based, in essence, on the application of materials and chemicals with persistent bactericidal or -static properties onto surfaces or in textiles used in healthcare environments...
April 28, 2017: Bioengineered
https://www.readbyqxmd.com/read/28449308/a-qualitative-study-of-the-knowledge-behaviour-and-attitudes-of-patients-with-skin-cancer-regarding-sunlight-exposure-and-vitamin-d
#20
D Rutkowski, M D Farrar, J E Osman, A R Webb, L E Rhodes
BACKGROUND: Solar UVR is a major cause of skin cancer but also an important source of vitamin D (VitD), essential for musculoskeletal health. Conflicting public health messages may confuse skin cancer patients prone to further skin cancer. OBJECTIVE: To explore the knowledge, behaviour and attitudes of skin cancer patients to sunlight exposure and VitD sources. METHODS: Patients (n=10) previously treated for multiple basal cell cancer in a hospital setting, participated in focus group sessions with semi-structured discussions to explore: knowledge of VitD, sun-avoidance behaviour, and attitude towards sunlight exposure messages...
April 27, 2017: Photodermatology, Photoimmunology & Photomedicine
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