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Cosmeceuticals

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https://www.readbyqxmd.com/read/29028862/alternatives-to-standard-injectables-and-devices-for-rejuvenation
#1
Sabine Zenker
<p>INTRODUCTION: Looking at alternatives to standard injectables and devices for rejuvenation, typical indications for facial rejuvenation are poor skin quality, pigmentary changes, and the loss of shape. Looking for effective treatments for those indications in the aesthetic field, one can notice a kind of "retro"-trend: easy-to-perform, non- or minimally-invasive, low-investment-requiring procedures are regaining a lot of popularity. And, over time, those treatments are becoming well defined and far more specific...
June 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29021700/ginsenoside-rg12-a-new-dammarane-type-triterpene-saponin-from-panax-ginseng-root
#2
Dong Gu Lee, Jaemin Lee, Ik-Hyun Cho, Hak-Jae Kim, Sang-Won Lee, Young-Ock Kim, Chun-Gun Park, Sanghyun Lee
BACKGROUND: Panax ginseng has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects. METHODS: A dammarane-type triterpene saponin was isolated from P. ginseng root through chromatography such as repeated column chromatography and medium pressure liquid chromatography. RESULTS AND CONCLUSION: New dammarane-type triterpene saponin was isolated for the first time from nature...
October 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28980914/bioactive-chemical-compounds-in-eremurus-persicus-joub-spach-boiss-essential-oil-and-their-health-implications
#3
B Salehi, S A Ayatollahi, A Segura-Carretero, F Kobarfard, M D M Contreras, M Faizi, M Sharifi-Rad, S A Tabatabai, J Sharifi-Rad
The genus Eremurus is native to Eastern Europe and temperate Asia. Particularly, Eremurus persicus (Joub. & Spach) Boiss. is highly valued in traditional foods and medicine. Scientific knowledge about E. persicus chemical composition and bioactivity is required. Therefore, the present study is aimed to determine the volatile composition of E. persicus essential oil (EO) by means of gas chromatography coupled to flame ionization/mass spectrometry detection. Moreover, the antioxidant, antimicrobial, anticancer, and acetylcholinesterase inhibitory activities of the EO were tested...
September 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28979664/oily-skin-a-review-of-treatment-options
#4
REVIEW
Dawnielle C Endly, Richard A Miller
One of the most common dermatologic concerns is oily skin, and the demand for effective treatment options is ever apparent. This review article addresses numerous topical treatment options such as retinoids, olumacostat glasaretil, and various cosmeceutical agents. several systemic and procedural techniques that incorporate isotretinoin, spironolactone, oral contraceptives, botulinum toxin, photodynamic therapy, and lasers are reviewed as well. Each treatment option is analyzed in terms of the proposed mechanism of action, efficacy reported in the literature, and potential adverse effects...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28962062/dermal-histology-in-mouse-skin-exposed-to-cosmeceuticals
#5
Tapan K Bhattacharyya, Hope Bueller, Yvonne Hsia, J Regan Thomas
No abstract text is available yet for this article.
October 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28946635/hypopigmenting-effects-of-brown-algae-derived-phytochemicals-a-review-on-molecular-mechanisms
#6
REVIEW
Mohammed Shariful Azam, Jinkyung Choi, Min-Sup Lee, Hyeung-Rak Kim
There is a rapid increase in the demand for natural hypopigmenting agents from marine sources for cosmeceutical and pharmaceutical applications. Currently, marine macroalgae are considered as a safe and effective source of diverse bioactive compounds. Many research groups are exploring marine macroalgae to discover and characterize novel compounds for cosmeceutical, nutraceutical, and pharmaceutical applications. Many types of bioactive secondary metabolites from marine algae, including phlorotannins, sulfated polysaccharides, carotenoids, and meroterpenoids, have already been documented for their potential applications in the pharmaceutical industry...
September 24, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28933269/drug-delivery-and-cosmeceutical-applications-of-polylactic-acid-based-novel-constructs-a-review
#7
Hafiz M N Iqbal, Federico Ruiz-Ruiz, Elena Ivonne Mancera-Andrade, Roberto Parra-Saldivar, Tajalli Keshavarz
In recent years, there has been a great research interest in bio-based biopolymers due to their potential as alternative polymers to the traditional petroleum-based synthetic counterparts. Research is underway around the globe on the development of 'greener' technologies. Recently, bio-based bio-constructs are being engineered for target applications in different bio- and non-bio sectors of the modern world to address growing concerns of a global dependence on non-renewable petroleum-based resources. The utilization of properly designed and structured materials thus allows for the creation of well-defined environment that induces a series of directed measures, and so on...
September 19, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28930258/an-aloe-vera-based-cosmeceutical-cream-delays-and-mitigates-ionizing-radiation-induced-dermatitis-in-head-and-neck-cancer-patients-undergoing-curative-radiotherapy-a-clinical-study
#8
Suresh Rao, Sanath Kumar Hegde, Manjeshwar Poonam Baliga-Rao, Princy Louis Palatty, Thomas George, Manjeshwar Shrinath Baliga
Background: This study was planned to evaluate the efficacy of topical application of an Aloe vera-based cream (AVC) for the prevention of ionizing radiation (X ray)-induced dermatitis in head and neck cancer patients requiring therapeutic radiation treatment (>62 Gy). Methods: From July 2012 to December 2012, a total of 60 head and neck cancer patients requiring curative radiotherapy (RT) of more than 66 Gy were prospectively enrolled and treated with AVC or a comparator Johnson's Baby Oil (JBO). Acute skin reaction was monitored and classified according to the Radiation Therapy Oncology Group (RTOG) four-point rating scale on a weekly basis...
June 24, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930256/vetiver-essential-oil-in-cosmetics-what-is-new
#9
Pauline Burger, Anne Landreau, Marie Watson, Laurent Janci, Viviane Cassisa, Marie Kempf, Stéphane Azoulay, Xavier Fernandez
Background: Vetiver is a key ingredient for the perfume industry nowadays. However, with the constant and rapid changes of personal tastes, this appeal could vanish and this sector could decline quite quickly. New dissemination paths need to be found to tap this valuable resource. Methods: In this way, its potential use in cosmetics either as an active ingredient per se (with cosmeceutical significance or presenting antimicrobial activity) has hence been explored in vitro. Results: In this contribution, we demonstrated that vetiver essential oil displays no particularly significant and innovative cosmetic potential value in formulations apart from its scent already largely exploited...
June 16, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28919860/a-multidirectional-perspective-for-novel-functional-products-in-vitro-pharmacological-activities-and-in-silico-studies-on-ononis-natrix-subsp-hispanica
#10
Serife Yerlikaya, Gokhan Zengin, Adriano Mollica, Mehmet C Baloglu, Yasemin Celik Altunoglu, Abdurrahman Aktumsek
The genus Ononis has important value as traditional drugs and foods. In the present work, we aimed to assess the chemical profiles and biological effects of Ononis natrix subsp. hispanica extracts (ethyl acetate, methanol, and water). For chemical profile, total and individual phenolic components were detected. For biological effects, antioxidant (DPPH, ABTS, CUPRAC, FRAP, phosphomolybdenum, and metal chelating assays), enzyme inhibitory (against cholinesterase, tyrosinase, α-amylase and α-glucosidase), antimicrobial, DNA protection and cytotoxic abilities were tested...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28900868/stability-of-organoleptic-agents-in-pharmaceuticals-and-cosmetics
#11
REVIEW
Akash Patil, Supriya Bhide, Mustafa Bookwala, Bhavik Soneta, Vijaykumar Shankar, Ahmed Almotairy, Mashan Almutairi, S Narasimha Murthy
Organoleptic agents constitute an important niche in the field of pharmaceutical excipients. These agents encompass a range of additives responsible for coloring, flavoring, sweetening, and texturing formulations. All these agents have come to play a significant role in pharmaceuticals and cosmetics due to their ability to increase patient compliance by elevating a formulation's elegance and esthetics. However, it is essential to review their physical and chemical attributes before use, as organoleptic agents, similar to active pharmaceutical ingredients (APIs), are susceptible to physical and chemical instability leading to degradation...
September 12, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28867759/development-and-optimization-of-orally-and-topically-applied-liquid-crystal-drug-formulations
#12
Wesam R Kadhum, Tomoki Hada, Ichiro Hijikuro, Hiroaki Todo, Kenji Sugibayashi
Liquid crystal (LC)-forming lipids represent an important class of biocompatible amphiphiles and their application extends to cosmeceutical, dietary, and pharmaceutical technologies. In the present study, we aimed to develop strategies for designing and optimizing oral and topical LC formulations by evaluating their in vitro and in vivo drug absorption performances. C17-Monoglycerol ester (MGE) was used as a LC-forming lipid. p-Amino benzoic acid, methyl PABA, ethyl PABA, and sodium fluorescein were selected as drug models with different physiochemical properties...
2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28854750/antioxidant-and-anti-inflammatory-properties-of-chicken-egg-vitelline-membrane-hydrolysates
#13
Dillon Lee, Fatemeh Bamdad, Kevin Khey, Hoon H Sunwoo
Vitelline membrane (VM) is a multilayered structure that surrounds the egg yolk serving to separate the yolk and the white. Due to its poor solubility in aqueous-based media, VM proteins and their biological properties have not been fully defined. In the current study, VM was hydrolyzed using different enzymes under the optimum hydrolysis conditions. Antioxidant and anti-inflammatory properties were evaluated in chemical and cellular models. Flavourzyme- and trypsin-treated samples showed the highest radical scavenging and ferric ion reducing effect (31% and 20 μM of Trolox equivalents/mg, respectively)...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28842180/purification-of-biomevalonate-from-fermentation-broth-and-conversion-of-biomevalonate-into-biomevalonolactone
#14
Jin Won Kim, Hee Chan Yoon, Soon Jae Kwon, Bun Yeol Lee, Pyung Cheon Lee
Mevalonate (MVA) is a key compound of living organisms including bacteria, plants, and humans. MVA and mevalonolactone (MVL), a lactonized form of MVA, are important for pharmaceutical, cosmeceutical, and biotechnological applications. Although (R, S)-MVA with 50% enantiomeric purity is mainly produced by chemical synthesis, recently, microbial fermentation processes for MVA production have been considered as an alternative to the chemical synthesis because of high enantiomeric purity [(R)-MVA] and high titer...
August 24, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28818741/identification-of-sterols-from-the-soft-coral-dendronephthya-gigantea-and-their-anti-inflammatory-potential
#15
I P Shanura Fernando, K K Asanka Sanjeewa, Hyun-Soo Kim, Seo-Young Kim, Seung-Hong Lee, Won Woo Lee, You-Jin Jeon
Exploration of anti-inflammatory phytochemicals has received tremendous attention worldwide owing to the rapid increase in inflammatory diseases. Current study reveals the identification of eight 3β-hydroxy-Δ(5)-steroidal congeners from a nonpolar column fraction of the ethanol solubles from the soft coral Dendronephthya gigantea collected from Jeju Island South Korea, using GC-MS/MS analysis. The sterol-rich fraction (DGEH21) showed a significant anti-inflammatory activity as exhibited by the inhibition of NO production (IC50 4...
August 9, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28799642/olive-tree-olea-europaea-l-leaf-as-a-waste-by-product-of-table-olive-and-olive-oil-industry-a-review
#16
REVIEW
Selin Şahin, Mehmet Bilgin
Researches into finding new uses for by-products of table olive and olive oil industry are of great value not only to the economy, but also to the environment where olives are grown and to the human health. Since leaves represent around 10% of the total weight of olives arriving to the mill, it is worth obtaining high added-value compounds from those materials for the preparation of dietary supplements, nutraceuticals, functional food ingredients or cosmeceuticals. In this review article, olive tree (Olea europaea L...
August 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28760544/the-potential-of-ganoderma-lucidum-extracts-as-bioactive-ingredients-in-topical-formulations-beyond-its-nutritional-benefits
#17
Oludemi Taofiq, Sandrina A Heleno, Ricardo C Calhelha, Maria José Alves, Lillian Barros, Ana M González-Paramás, Maria F Barreiro, Isabel C F R Ferreira
Ganoderma lucidum was characterized in terms of nutritional value and chemical composition. Thereafter, ethanolic Soxhlet extracts were evaluated for antioxidant, anti-inflammatory, antityrosinase, antimicrobial and cytotoxic effects, and further characterized in terms of phenolic acids, polysaccharides and triterpenoids. Finally, the obtained extracts were tested as cosmeceutical ingredients. G. lucidum proved to be a source of macronutrients and important bioactive compounds such as terpenoids, specially triterpenoids, and polysaccharides...
July 29, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28753056/gamma-irradiated-luteolin-inhibits-3-isobutyl-1-methylxanthine-induced-melanogenesis-through-the-regulation-of-creb-mitf-pi3k-akt-and-erk-pathways-in-b16bl6-melanoma-cells
#18
Eui-Baek Byun, Ha-Yeon Song, Sajid Mushtaq, Hye-Min Kim, Jung Ae Kang, Mi-So Yang, Nak-Yun Sung, Beom-Su Jang, Eui-Hong Byun
Luteolin was gamma irradiated at doses of 0, 15, 30, 50, 70, and 100 kGy. We observed that the luteolin peak decreased simultaneously with the appearance of new radiolytic peaks, using high-performance liquid chromatography (HPLC). The highest new radiolytic peak (GLM) of radiolytic product in gamma-irradiated luteolin was observed at a dose of 70 kGy, and the GLM was identified by nuclear magnetic resonance and high-performance-liquid-chromatography-quadrupole-time-of-flight (HPLC-Q-TOF) mass spectrometry...
August 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28728492/the-bioactivity-of-hedysarum-coronarium-extracts-on-skin-enzymes-and-cells-correlates-with-phenolic-content
#19
Bruno Burlando, Giulia Pastorino, Annalisa Salis, Gianluca Damonte, Marco Clericuzio, Laura Cornara
CONTEXT: The search for bioactive compounds from botanical sources is attracting much interest. However, differences in chemical composition may occur within the same species depending on different geographical origins. OBJECTIVES: We evaluated the properties on skin enzymes and cells of extracts from sulla legume crop Hedysarum coronarium L. (Fabaceae), collected at two Italian sites near Pisa and Ventimiglia, for possible dermatological and cosmetic applications...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28697219/the-role-of-a-natural-mollusk-egg-derived-ingredient-in-facial-appearance
#20
Zoe Diana Draelos
<p>New cosmeceutical ingredients that improve skin appearance are of interest to the dermatologist. Cryptomphalus aspersa is a snail raised on farms in Spain for its mucinous secretions and eggs. These natural products have been demonstrated in vitro to trigger mesenchymal stem cell differentiation, promote dermal fibroblast and keratinocyte migration, prevent keratinocyte aging, prevent oxidative damage, stimulate the extracellular matrix, and regulate MMPs. This 12-week study enrolled 40 male and female subjects age 40-70 years of Fitzpatrick skin types I-IV with moderate to severe facial aging and Rao-Goldman scores of 4-5 who applied an eye and face anti-aging cream twice daily containing a mollusk egg extract...
July 1, 2017: Journal of Drugs in Dermatology: JDD
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