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Cosmeceuticals

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https://www.readbyqxmd.com/read/27918006/cosmeceuticals-in-skin-of-color
#1
Leslie Baumann
Patients with skin of color have similar skin care needs as lighter-skin patients. However, they are less likely to use sun protection on a daily basis, which leads to an increased risk of dyschromia, skin cancer, and other disorders. This article discusses the importance of a correct and consistent skin care regimen and the various cutaneous issues that should be considered when prescribing a skin care regimen for patients with darker skin types. Adopting a standardized methodology to identify affordable, efficacious products and to streamline the process of skin-type diagnosis, skin care regimen prescribing, patient communication, and staff education will result in improved patient outcomes and increased patient satisfaction...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27914965/a-review-on-synthesis-properties-and-applications-of-natural-polymer-based-carrageenan-blends-and-composites
#2
REVIEW
Khalid Mahmood Zia, Shazia Tabasum, Muhammad Nasif, Neelam Sultan, Nosheen Aslam, Aqdas Noreen, Mohammad Zuber
Carrageenan is a natural polysaccharide extracted from edible red seaweeds of Rhodophycea class. It has been used as a viscosity increasing or gelling agent for prolonged and controlled drug release, food, pharmaceuticals and other industries. However, in spite of wide range of applications, carrageenan has some drawbacks and adverse effects on the biological systems, so its modifications with natural and synthetic polymers are carried out. This review article presents different sources and properties of carrageenans with special emphasis on natural polymer based carrageenan blends and composites and their applications in controlled drug delivery system, wound dressing and tissue engineering because of their biodegradability and biocompatibility, food industry as thickening/gelling materials, cosmeceuticals and making polyelectrolyte complexes...
November 30, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27865609/recent-advances-in-lipid-based-vesicles-and-particulate-carriers-for-topical-and-transdermal-application
#3
REVIEW
Shashank Jain, Niketkumar Patel, Mansi K Shah, Pinak Khatri, Namrata Vora
In the recent decade, skin delivery (topical and transdermal) has gained an unprecedented popularity, especially due to increased incidences of chronic skin diseases, demand for targeted and patient compliant delivery, and interest in life cycle management strategies among pharmaceutical companies. Literature review of recent publications indicates that among various skin delivery systems, lipid-based delivery systems (vesicular carriers and lipid particulate systems) have been the most successful. Vesicular carriers consist of liposomes, ultradeformable liposomes, and ethosomes, while lipid particulate systems consist of lipospheres, solid lipid nanoparticles, and nanostructured lipid carriers...
November 16, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27859298/experimental-and-theoretical-study-of-the-influence-of-water-on-hydrolyzed-product-formation-during-the-feruloylation-of-vegetable-oil
#4
David L Compton, Kervin O Evans, Michael Appell
BACKGROUND: Feruloylated vegetable oil is a valuable green bioproduct that has several cosmeceutical applications associated with its inherent anti-oxidant and UV-absorption properties. Hydrolyzed vegetable oil by-products can influence product quality and consistency. RESULTS: The formation of by-products by residual water in the enzymatic synthesis of feruloylated vegetable oil was investigated using chemical theory and experimental studies by monitoring the reaction over a 22 day period...
November 18, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27842483/patents-on-therapeutic-and-cosmetic-applications-of-bioactives-of-crocus-sativus-l-and-their-production-through-synthetic-biology-methods-a-review
#5
Mitali Nitin Dawalbhakta, Manasi Alok Telang
BACKGROUND: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. OBJECTIVE: The aim of this study was to carry out an extensive patent search to collect information on saffron bioactives and their derivatives as therapeutic and cosmeceutical agents. All patents related to the area of interest published globally till date have been reviewed...
November 14, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27775594/extracellular-metabolites-from-industrial-microalgae-and-their-biotechnological-potential
#6
Lu Liu, Georg Pohnert, Dong Wei
Industrial microalgae, as a big family of promising producers of renewable biomass feedstock, have been commercially exploited for functional food, living feed and feed additives, high-value chemicals in nutraceuticals, cosmeceuticals, and chemical reagents. Recently, microalgae have also been considered as a group that might play an important role in biofuel development and environmental protection. Almost all current products of industrial microalgae are derived from their biomass; however, large amounts of spent cell-free media are available from mass cultivation that is mostly unexploited...
October 20, 2016: Marine Drugs
https://www.readbyqxmd.com/read/27754433/development-of-mushroom-based-cosmeceutical-formulations-with-anti-inflammatory-anti-tyrosinase-antioxidant-and-antibacterial-properties
#7
Oludemi Taofiq, Sandrina A Heleno, Ricardo C Calhelha, Maria José Alves, Lillian Barros, Maria Filomena Barreiro, Ana M González-Paramás, Isabel C F R Ferreira
The cosmetic industry is in a constant search for natural compounds or extracts with relevant bioactive properties, which became valuable ingredients to design cosmeceutical formulations. Mushrooms have been markedly studied in terms of nutritional value and medicinal properties. However, there is still slow progress in the biotechnological application of mushroom extracts in cosmetic formulations, either as antioxidants, anti-aging, antimicrobial, and anti-inflammatory agents or as hyperpigmentation correctors...
October 14, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27697492/blends-and-composites-of-exopolysaccharides-properties-and-applications-a-review
#8
REVIEW
Abid Hussain, Khalid Mahmood Zia, Shazia Tabasum, Aqdas Noreen, Muhammad Ali, Rehana Iqbal, Mohammad Zuber
Exopolysaccharides are synthesized by bacteria and secreted into the external environment and they may be homopolymeric or heteropolymeric in configuration. They are believed to protect bacterial cells from heavy metals, desiccation or other environmental effect. EPS exhibit antitumor, anti-HIV, emulsion stabilization capacity, shear-thinning activity, suspension ability, high viscosities, excellent biocompatibility, high biodegradability and immunomodulatory properties. They are widely used in herbicides, functional food, nutraceuticals, cosmeceuticals, pharmaceuticals, insecticides, immunomodulation and anticoagulants...
October 3, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27673445/physical-and-biological-characterization-of-sericin-loaded-copolymer-liposomes-stabilized-by-polyvinyl-alcohol
#9
Kunat Suktham, Thongchai Koobkokkruad, Somsak Saesoo, Nattika Saengkrit, Suvimol Surassmo
Sericin protein (SP) is widely used as a nutrient biomaterial for biomedical and cosmeceutical applications although it shows low stability to heat and light. To overcome these problems and add value to wastewater from the silk industry, sericin protein was recovered as sericin-loaded copolymer-liposomes (SP-PVA-LP), prepared through thin film hydration. The size and morphology of the liposomes were investigated using dynamic light scattering (DLS), and electron microscopy (SEM and TEM). The particle size, liposome surface morphology and encapsulation efficiency of SP were dependent on PVA concentration...
September 21, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27621603/chum-salmon-egg-extracts-induce-upregulation-of-collagen-type-i-and-exert-antioxidative-effects-on-human-dermal-fibroblast-cultures
#10
Atsushi Yoshino, Natalia Polouliakh, Akira Meguro, Masaki Takeuchi, Tatsukata Kawagoe, Nobuhisa Mizuki
Components of fish roe possess antioxidant and antiaging activities, making them potentially very beneficial natural resources. Here, we investigated chum salmon eggs (CSEs) as a source of active ingredients, including vitamins, unsaturated fatty acids, and proteins. We incubated human dermal fibroblast cultures for 48 hours with high and low concentrations of CSE extracts and analyzed changes in gene expression. Cells treated with CSE extract showed concentration-dependent upregulation of collagen type I genes and of multiple antioxidative genes, including OXR1, TXNRD1, and PRDX family genes...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27570454/eupafolin-nanoparticles-protect-hacat-keratinocytes-from-particulate-matter-induced-inflammation-and-oxidative-stress
#11
Zih-Chan Lin, Chiang-Wen Lee, Ming-Horng Tsai, Horng-Huey Ko, Jia-You Fang, Yao-Chang Chiang, Chan-Jung Liang, Lee-Fen Hsu, Stephen Chu-Sung Hu, Feng-Lin Yen
Exposure to particulate matter (PM), a major form of air pollution, can induce oxidative stress and inflammation and may lead to many diseases in various organ systems including the skin. Eupafolin, a flavonoid compound derived from Phyla nodiflora, has been previously shown to exhibit various pharmacological activities, including antioxidant and anti-inflammatory effects. Unfortunately, eupafolin is characterized by poor water solubility and skin penetration, which limits its clinical applications. To address these issues, we successfully synthesized a eupafolin nanoparticle delivery system (ENDS)...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27530764/micro-needling-depth-penetration-presence-of-pigment-particles-and-fluorescein-stained-platelets-clinical-usage-for-aesthetic-concerns
#12
Gordon H Sasaki
BACKGROUND: Aesthetic micro-needling (MN) has demonstrated skin permeability to cosmeceutical ingredients and platelet-rich plasma by creating reversible micro-channels in the skin. OBJECTIVES: The purposes of this study were to determine: (1) actual needle depth-penetrations by adjusting needle lengths in a disposable tip of an electric MN device; (2) time-dependent passage of pigment and platelets; and (3) safety and efficacy profiles in patients. METHODS: Excised micro-needled pre-auricular skin was used to determine actual depths of tissue penetration with six needle lengths, and the presence of massaged pigment particles (histological examination) and fluorescein-labeled platelets (confocal laser microscopy) in 1 mm depth micro-channels over an hour...
August 16, 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27527190/acetylated-triterpene-glycosides-and-their-biological-activity-from-holothuroidea-reported-in-the-past-six-decades
#13
REVIEW
Yadollah Bahrami, Christopher M M Franco
Sea cucumbers have been valued for many centuries as a tonic and functional food, dietary delicacies and important ingredients of traditional medicine in many Asian countries. An assortment of bioactive compounds has been described in sea cucumbers. The most important and abundant secondary metabolites from sea cucumbers are triterpene glycosides (saponins). Due to the wide range of their potential biological activities, these natural compounds have gained attention and this has led to their emergence as high value compounds with extended application in nutraceutical, cosmeceutical, medicinal and pharmaceutical products...
2016: Marine Drugs
https://www.readbyqxmd.com/read/27521253/skin-aging-and-oxidative-stress-equol-s-anti-aging-effects-via-biochemical-and-molecular-mechanisms
#14
REVIEW
Edwin D Lephart
Oxygen in biology is essential for life. It comes at a cost during normal cellular function, where reactive oxygen species (ROS) are generated by oxidative metabolism. Human skin exposed to solar ultra-violet radiation (UVR) dramatically increases ROS production/oxidative stress. It is important to understand the characteristics of human skin and how chronological (intrinsic) aging and photo-aging (extrinsic aging) occur via the impact of ROS production by cascade signaling pathways. The goal is to oppose or neutralize ROS insults to maintain good dermal health...
November 2016: Ageing Research Reviews
https://www.readbyqxmd.com/read/27496663/fifty-years-of-research-and-development-of-cosmeceuticals-a-contemporary-review
#15
Chun-Man Lee
Facial rejuvenation can be categorized into skincare and facial contouring. Research and development of cosmeceuticals is aimed at addressing the major signs of photoaging: wrinkles, dyschromia, and sallowness. Assessment of photoaging comes in clinical and photographic forms; a photonumeric scale developed by Griffiths et al. has been assured of its validity and reliability for the assessment of severity of photoaging in qualitative studies. Treatment of photoaging comes in two categories: preventive and reversal of signs; whilst sunfactors are the most efficient and essential in preventing photodamage, research and development of cosmeceuticals for facial rejuvenation has been robust, thanks to several landmark studies in the last fifty years, funded by some of the forerunners in contemporary cosmetic industry...
August 6, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27463789/empty-nano-and-micro-structured-lipid-carriers-of-virgin-coconut-oil-for-skin-moisturisation
#16
Norhayati Mohamed Noor, Abid Ali Khan, Rosnani Hasham, Ayesha Talib, Mohamad Roji Sarmidi, Ramlan Aziz, Azila Abd Aziz
Virgin coconut oil (VCO) is the finest grade of coconut oil, rich in phenolic content, antioxidant activity and contains medium chain triglycerides (MCTs). In this work formulation, characterisation and penetration of VCO-solid lipid particles (VCO-SLP) have been studied. VCO-SLP were prepared using ultrasonication of molten stearic acid and VCO in an aqueous solution. The electron microscopy imaging revealed that VCO-SLP were solid and spherical in shape. Ultrasonication was performed at several power intensities which resulted in particle sizes of VCO-SLP ranged from 0...
August 2016: IET Nanobiotechnology
https://www.readbyqxmd.com/read/27451932/topical-peptides-as-cosmeceuticals
#17
REVIEW
Varadraj Vasant Pai, Prasana Bhandari, Pankaj Shukla
Peptides are known to have diverse biological roles, most prominently as signaling/regulatory molecules in a broad variety of physiological processes including defense, immunity, stress, growth, homeostasis and reproduction. These aspects have been used in the field of dermatology and cosmetology to produce short, stable and synthetic peptides for extracellular matrix synthesis, pigmentation, innate immunity and inflammation. The evolution of peptides over the century, which started with the discovery of penicillin, has now extended to their usage as cosmeceuticals in recent years...
July 18, 2016: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/27443881/biological-properties-of-mud-extracts-derived-from-various-spa-resorts
#18
Eliana Spilioti, Margarita Vargiami, Sophia Letsiou, Konstantinos Gardikis, Varvara Sygouni, Petros Koutsoukos, Ioanna Chinou, Eva Kassi, Paraskevi Moutsatsou
Spa resorts are known for thousands of years for their healing properties and have been empirically used for the treatment of many inflammatory conditions. Mud is one of the most often used natural materials for preventive, healing and cosmetic reasons and although it has been used since the antiquity, little light has been shed on its physical, chemical and biological properties. In this study we examined the effect of mud extracts on the expression of adhesion molecules (CAMs) by endothelial cells as well as their effects on monocyte adhesion to activated endothelial cells...
July 21, 2016: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/27424198/traditional-herbal-prescription-lasap-c-inhibits-melanin-synthesis-in-b16f10-melanoma-cells-and-zebrafish
#19
Min Kyoung Kim, Chae Young Bang, Mi Yoon Kim, Jeung-Hoon Lee, Hyunju Ro, Min-Sun Choi, Dong-Il Kim, Young Pyo Jang, Se Young Choung
BACKGROUND: In this study, the anti-melanogenesis efficacy of clinically used herbal prescription LASAP-C, which consists of four herbal medicines-Rehmanniae Radix Crudus, Lycii Fructus, Scutellariae Radix, and Angelicae Dahuricae Radix, was investigated. METHODS: The chemical profile of LASAP-C was established by conducting ultra-performance liquid chromatography-electrospray ionization-mass spectrometry. Anti-melanogenic efficacy was evaluated by tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2 expression in B16F10 melanoma cells...
2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27398005/infraorbital-dark-circles-a-review-of-the-pathogenesis-evaluation-and-treatment
#20
Ivan Vrcek, Omar Ozgur, Tanuj Nakra
Infraorbital dark circles represent a common and multifactorial challenge in the world of aesthetic medicine and are the result of a variety of factors including deep facial anatomy, soft tissue changes, as well as contributions from the skin. A variety of treatment options exist, and a customised management strategy can be developed for the particular anatomic changes present. A literature search using MEDLINE and non-MEDLINE sources was performed utilising keywords including: 'Dark circles' 'infraorbital dark circles', 'infraorbital pigment', 'under-eye circles' and 'lower eyelid bags'...
April 2016: Journal of Cutaneous and Aesthetic Surgery
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