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https://www.readbyqxmd.com/read/29345224/therapy-interventions-for-children-with-neurodisabilities-a-qualitative-scoping-study
#1
Bryony Beresford, Susan Clarke, Jane Maddison
BACKGROUND: Therapy interventions emerged four times in the top 10 research priorities in a James Lind Alliance research prioritisation exercise for children with neurodisabilities (Morris C, Simkiss D, Busk M, Morris M, Allard A, Denness J, et al. Setting research priorities to improve the health of children and young people with neurodisability: a British Academy of Childhood Disability-James Lind Alliance Research Priority Setting Partnership. BMJ Open 2015;5:e006233). The National Institute for Health Research (NIHR) commissioned this study as part of an information-gathering exercise in response to this...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29344794/ticagrelor-for-secondary-prevention-of-atherothrombotic-events-after-myocardial-infarction-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#2
REVIEW
Xavier G L V Pouwels, Robert Wolff, Bram L T Ramaekers, Anoukh Van Giessen, Shona Lang, Steve Ryder, Gill Worthy, Steven Duffy, Nigel Armstrong, Jos Kleijnen, Manuela A Joore
The National Institute for Health and Care Excellence (NICE) invited AstraZeneca, the manufacturer of ticagrelor (Brilique®), to submit evidence on the clinical and cost effectiveness of ticagrelor 60 mg twice daily (BID) in combination with low-dose aspirin [acetylsalicylic acid (ASA)] compared with ASA only for secondary prevention of atherothrombotic events in patients with a history of myocardial infarction (MI) and who are at increased risk of atherothrombotic events. Kleijnen Systematic Reviews Ltd (KSR), in collaboration with Maastricht University Medical Centre+, was commissioned as the evidence review group (ERG)...
January 18, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29343412/implementing-genome-driven-personalized-cardiology-in-clinical-practice
#3
REVIEW
Ares Pasipoularides
Genomics designates the coordinated investigation of a large number of genes in the context of a biological process or disease. It may be long before we attain comprehensive understanding of the genomics of common complex cardiovascular diseases (CVDs) such as inherited cardiomyopathies, valvular diseases, primary arrhythmogenic conditions, congenital heart syndromes, hypercholesterolemia and atherosclerotic heart disease, hypertensive syndromes, and heart failure with preserved/reduced ejection fraction. Nonetheless, as genomics is evolving rapidly, it is constructive to survey now pertinent concepts and breakthroughs...
January 14, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29342932/interstitial-glucose-and-physical-exercise-in-type-1-diabetes-integrative-physiology-technology-and-the-gap-in-between
#4
REVIEW
Othmar Moser, Jane E Yardley, Richard M Bracken
Continuous and flash glucose monitoring systems measure interstitial fluid glucose concentrations within a body compartment that is dramatically altered by posture and is responsive to the physiological and metabolic changes that enable exercise performance in individuals with type 1 diabetes. Body fluid redistribution within the interstitial compartment, alterations in interstitial fluid volume, changes in rate and direction of fluid flow between the vasculature, interstitium and lymphatics, as well as alterations in the rate of glucose production and uptake by exercising tissues, make for caution when interpreting device read-outs in a rapidly changing internal environment during acute exercise...
January 15, 2018: Nutrients
https://www.readbyqxmd.com/read/29342102/development-of-a-high-sensitivity-wireless-accelerometer-for-structural-health-monitoring
#5
Li Zhu, Yuguang Fu, Raymond Chow, Billie F Spencer, Jong Woong Park, Kirill Mechitov
Structural health monitoring (SHM) is playing an increasingly important role in ensuring the safety of structures. A shift of SHM research away from traditional wired methods toward the use of wireless smart sensors (WSS) has been motivated by the attractive features of wireless smart sensor networks (WSSN). The progress achieved in Micro Electro-Mechanical System (MEMS) technologies and wireless data transmission, has extended the effectiveness and range of applicability of WSSNs. One of the most common sensors employed in SHM strategies is the accelerometer; however, most accelerometers in WSS nodes have inadequate resolution for measurement of the typical accelerations found in many SHM applications...
January 17, 2018: Sensors
https://www.readbyqxmd.com/read/29340235/evidence-based-design-and-evaluation-of-a-whole-genome-sequencing-clinical-report-for-the-reference-microbiology-laboratory
#6
Anamaria Crisan, Geoffrey McKee, Tamara Munzner, Jennifer L Gardy
Background: Microbial genome sequencing is now being routinely used in many clinical and public health laboratories. Understanding how to report complex genomic test results to stakeholders who may have varying familiarity with genomics-including clinicians, laboratorians, epidemiologists, and researchers-is critical to the successful and sustainable implementation of this new technology; however, there are no evidence-based guidelines for designing such a report in the pathogen genomics domain...
2018: PeerJ
https://www.readbyqxmd.com/read/29339936/satellite-stories-capturing-professional-experiences-of-academic-health-sciences-librarians-working-in-delocalized-health-sciences-programs
#7
Jackie Phinney, Amanda Rose Horsman
Objective: Health sciences training programs have progressively expanded onto satellite campuses, allowing students the opportunity to learn in communities away from an academic institution's main campus. This expansion has encouraged a new role for librarians to assume, in that a subset of health sciences librarians identify as "satellite librarians" who are permanently located at a distance from the main campus. Due to the unique nature of this role and lack of existing data on the topic, the authors investigated the experiences and perceptions of this unique group of information professionals...
January 2018: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/29339933/roles-for-librarians-in-systematic-reviews-a-scoping-review
#8
Angela J Spencer, Jonathan D Eldredge
Objective: What roles do librarians and information professionals play in conducting systematic reviews? Librarians are increasingly called upon to be involved in systematic reviews, but no study has considered all the roles librarians can perform. This inventory of existing and emerging roles aids in defining librarians' systematic reviews services. Methods: For this scoping review, the authors conducted controlled vocabulary and text-word searches in the PubMed; Library, Information Science & Technology Abstracts; and CINAHL databases...
January 2018: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/29337204/the-positive-impacts-of-real-world-data-on-the-challenges-facing-the-evolution-of-biopharma
#9
REVIEW
John Wise, Angeli Möller, David Christie, Dipak Kalra, Elia Brodsky, Evelina Georgieva, Greg Jones, Ian Smith, Lars Greiffenberg, Marie McCarthy, Michael Arend, Olivier Luttringer, Sebastian Kloss, Steve Arlington
Demand for healthcare services is unprecedented. Society is struggling to afford the cost. Pricing of biopharmaceutical products is under scrutiny, especially by payers and Health Technology Assessment agencies. As we discuss here, rapidly advancing technologies, such Real-World Data (RWD), are being utilized to increase understanding of disease. RWD, when captured and analyzed, produces the Real-World Evidence (RWE) that underpins the economic case for innovative medicines. Furthermore, RWD can inform the understanding of disease, help identify new therapeutic intervention points, and improve the efficiency of research and development (R&D), especially clinical trials...
January 11, 2018: Drug Discovery Today
https://www.readbyqxmd.com/read/29336344/-the-urologist-of-the-future-and-new-technologies
#10
Francois Peinado, Atanasio Fernández, Fernando Teba, Guillermo Celada, Marco Antonio Acosta
The last 25 years have brought about revolutionary changes for medicine and in particular for urology: internet was only in its infancy, medical records were written on paper, searches for medical information were done in the hospital library, medical articles were photocopied and our relationship with patients only existed face to face. Social networks had not yet appeared and even Google did not exist. Just imagine what might happen during the next 25 years, we're going to see even more radical changes. The urologist of the future is going to see the arrival of artificial intelligence, collaborative medicine, telemedicine, machine learning, the Internet of Things and personalized robotics; in the meantime, social media will continue to transform the interaction between physician and patient...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29335236/tanzania-health-information-technology-t-hit-system-pilot-test-of-a-tablet-based-system-to-improve-prevention-of-mother-to-child-transmission-of-hiv
#11
Sheana Bull, Deborah Sk Thomas, Elias C Nyanza, Sospatro E Ngallaba
BACKGROUND: The prevention of mother-to-child transmission (PMTCT) of HIV requires innovative solutions. Although routine monitoring is effective in some areas, standardized and easy-to-scale solutions to identify and monitor pregnant women, test them for HIV, and treat them and their children is still lacking. Mobile health (mHealth) offers opportunities for surveillance and reporting in rural areas of low- and middle-income countries. OBJECTIVE: The aim of this study was to document the preliminary impacts of the Tanzania Health Information Technology (T-HIT) system mHealth intervention aimed at health workers for PMTCT care delivery and capacity building in a rural area of Tanzania...
January 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29335235/va-fitheart-a-mobile-app-for-cardiac-rehabilitation-usability-study
#12
Alexis L Beatty, Sara L Magnusson, John C Fortney, George G Sayre, Mary A Whooley
BACKGROUND: Cardiac rehabilitation (CR) improves outcomes for patients with ischemic heart disease or heart failure but is underused. New strategies to improve access to and engagement in CR are needed. There is considerable interest in technology-facilitated home CR. However, little is known about patient acceptance and use of mobile technology for CR. OBJECTIVE: The aim of this study was to develop a mobile app for technology-facilitated home CR and seek to determine its usability...
January 15, 2018: JMIR Human Factors
https://www.readbyqxmd.com/read/29335234/a-patient-held-smartcard-with-a-unique-identifier-and-an-mhealth-platform-to-improve-the-availability-of-prenatal-test-results-in-rural-nigeria-demonstration-study
#13
Semiu Olatunde Gbadamosi, Chuka Eze, John Olajide Olawepo, Juliet Iwelunmor, Daniel F Sarpong, Amaka Grace Ogidi, Dina Patel, John Okpanachi Oko, Chima Onoka, Echezona Edozie Ezeanolue
BACKGROUND: Community-based strategies to test for HIV, hepatitis B virus (HBV), and sickle cell disease (SCD) have expanded opportunities to increase the proportion of pregnant women who are aware of their diagnosis. In order to use this information to implement evidence-based interventions, these results have to be available to skilled health providers at the point of delivery. Most electronic health platforms are dependent on the availability of reliable Internet connectivity and, thus, have limited use in many rural and resource-limited settings...
January 15, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29334953/care-relationships-at-stake-home-healthcare-professionals-experiences-with-digital-medicine-dispensers-a-qualitative-study
#14
Sigrid Nakrem, Marit Solbjør, Ida Nilstad Pettersen, Hanne Hestvik Kleiven
BACKGROUND: Although digital technologies can mitigate the burdens of home healthcare services caused by an ageing population that lives at home longer with complex health problems, research on the impacts and consequences of digitalised remote communication between patients and caregivers is lacking. The present study explores how home healthcare professionals had experienced the introduction of digital medicine dispensers and their influence on patient-caregiver relationships. METHODS: The multi-case study comprised semi-structured interviews with 21 healthcare professionals whose home healthcare service involved using the digital medicine dispensers...
January 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29334475/abandonment-of-assistive-products-assessing-abandonment-levels-and-factors-that-impact-on-it
#15
André T Sugawara, Vinícius D Ramos, Fábio M Alfieri, Linamara R Battistella
PURPOSE: To investigate the levels and factors that influence the abandonment of assistive products by users of a local reference rehabilitation center. METHODS: This observational study involved users who received services and assistive products provided by our center of rehabilitation. Users were identified using the records of the center and their responses about the abandonment were collected through face-to-face interviews. RESULTS: The abandonment level of assistive products was 19...
January 15, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29334198/enzyme-based-glucose-sensor-from-invasive-to-wearable-device
#16
REVIEW
Hyunjae Lee, Yongseok Joseph Hong, Seungmin Baik, Taeghwan Hyeon, Dae-Hyeong Kim
Blood glucose concentration is a key indicator of patients' health, particularly for symptoms associated with diabetes mellitus. Because of the large number of diabetic patients, many approaches for glucose measurement have been studied to enable continuous and accurate glucose level monitoring. Among them, electrochemical analysis is prominent because it is simple and quantitative. This technology has been incorporated into commercialized and research-level devices from simple test strips to wearable devices and implantable systems...
January 15, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29331258/clinician-user-involvement-in-the-real-world-designing-an-electronic-tool-to-improve-interprofessional-communication-and-collaboration-in-a-hospital-setting
#17
Terence Tang, Morgan E Lim, Elizabeth Mansfield, Alexander McLachlan, Sherman D Quan
OBJECTIVES: User involvement is vital to the success of health information technology implementation. However, involving clinician users effectively and meaningfully in complex healthcare organizations remains challenging. The objective of this paper is to share our real-world experience of applying a variety of user involvement methods in the design and implementation of a clinical communication and collaboration platform aimed at facilitating care of complex hospitalized patients by an interprofessional team of clinicians...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29331256/measuring-non-administration-of-ordered-medications-in-the-pediatric-inpatient-setting
#18
Haresh L Bhatia, Neal R Patel, Catherine H Ivory, Phillip W Stewart, Kim M Unertl, Christoph U Lehmann
OBJECTIVE: Medication compliance in inpatient settings shows some significant gaps for adult patients. In pediatric settings prescribing and other administration errors have been studied but missed doses have not been specifically studied in the pediatric inpatient setting. We intended to apply health information technology and data processing methods to study the medication compliance for pediatric patients at our institution. STUDY DESIGN: We collected medication ordering, dispensing, and administration data spanning 42 months (7/1/2010 through 12/31/2013) for pediatric inpatients admitted to a major tertiary pediatric hospital...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29331252/investigating-the-need-for-clinicians-to-use-tablet-computers-with-a-newly-envisioned-electronic-health-record
#19
Jason J Saleem, April Savoy, Gale Etherton, Jennifer Herout
OBJECTIVE: The Veterans Health Administration (VHA) has deployed a large number of tablet computers in the last several years. However, little is known about how clinicians may use these devices with a newly planned Web-based electronic health record (EHR), as well as other clinical tools. The objective of this study was to understand the types of use that can be expected of tablet computers versus desktops. METHODS: Semi-structured interviews were conducted with 24 clinicians at a Veterans Health Administration (VHA) Medical Center...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29331251/bridging-clinical-researcher-perceptions-and-health-it-realities-a-case-study-of-stakeholder-creep
#20
Daniel J Panyard, Edmond Ramly, Shannon M Dean, Christie M Bartels
PURPOSE: We present a case report detailing a challenge in health information technology (HIT) project implementations we term "stakeholder creep": not thoroughly identifying which stakeholders need to be involved and why before starting a project, consequently not understanding the true effort, skill sets, social capital, and time required to complete the project. METHODS: A root cause analysis was performed post-implementation to understand what led to stakeholder creep...
February 2018: International Journal of Medical Informatics
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