keyword
https://read.qxmd.com/read/38547480/impact-of-parent-presence-and-engagement-on-stress-in-nicu-infants
#1
JOURNAL ARTICLE
Susan Horner
BACKGROUND: Infants in neonatal intensive care units (NICUs) are exposed to frequent stressors that impact their neurodevelopmental outcomes. Parent presence and engagement are considered critical to improving infant outcomes, yet associations between cumulative NICU parent presence, engagement, and infant stress are infrequently examined. PURPOSE: To examine associations between NICU infant stress and the amount (hours per week) or frequency (days per week) of parent presence and skin-to-skin care (SSC)...
April 1, 2024: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://read.qxmd.com/read/38547139/association-between-sociodemographic-factors-clinic-characteristics-and-mental-health-screening-rates-in-primary-care
#2
JOURNAL ARTICLE
Frank Müller, Alyssa M Abdelnour, Diana N Rutaremara, Judith E Arnetz, Eric D Achtyes, Omayma Alshaarawy, Harland T Holman
BACKGROUND: Screening for mental health problems has been shown to be effective to detect depression and initiate treatment in primary care. Current guidelines recommend periodic screening for depression and anxiety. This study examines the association of patient sociodemographic factors and clinic characteristics on mental health screening in primary care. DESIGN: In this retrospective cohort study, electronic medical record (EMR) data from a 14-month period from 10/15/2021 to 12/14/2022 were analyzed...
2024: PloS One
https://read.qxmd.com/read/38547078/using-the-electronic-medical-record-to-address-code-status-documentation-a-quality-improvement-project
#3
JOURNAL ARTICLE
John Sorge, Susan Szpunar, Theodore Daniel, Louis Saravolatz
Code status (CS) is often overlooked while admitting patients to the hospital. This is important for patients with end-stage disease. This quality improvement project investigated whether a CS pop-up alert in the electronic medical record, combined with provider education, improved addressing CS. The project consisted of a baseline chart review, implementation of the alert and physician education, and a postintervention chart review. We reviewed 1828 charts at baseline and 1,775 at postintervention. From univariable analysis, there were improvements in addressing CS, being full code, cardiopulmonary resuscitation, intubation, use of vasopressors, and cardioversion technique categories (all p < ...
March 28, 2024: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://read.qxmd.com/read/38546726/implementation-of-cyp2c19-and-cyp2d6-genotyping-to-guide-antidepressant-use-in-a-large-rural-health-system
#4
JOURNAL ARTICLE
Natasha J Petry, Joel Van Heukelom, April J Schultz, Kristen Jacobsen, Jordan F Baye, Sarah Mills, Debbie Figueroa, Amanda Massmann
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: We describe the implementation and ongoing maintenance of CYP2C19 and CYP2D6 focused pharmacogenetic (PGx) testing to guide antidepressant and antianxiety medication prescriptions in a large rural, nonprofit health system...
March 28, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38546379/use-of-sequential-hot-deck-imputation-for-missing-health-care-systems-data-for-population-health-research
#5
JOURNAL ARTICLE
Ella A Chrenka, Steven P Dehmer, Michael V Maciosek, Inih J Essien, Bjorn C Westgard
Electronic medical record (EMR) data present many opportunities for population health research. The use of EMR data for population risk models can be impeded by the high proportion of missingness in key patient variables. Common approaches like complete case analysis and multiple imputation may not be appropriate for some population health initiatives that require a single, complete analytic data set. In this study, we demonstrate a sequential hot-deck imputation (HDI) procedure to address missingness in a set of cardiometabolic measures in an EMR data set...
March 28, 2024: Medical Care
https://read.qxmd.com/read/38546170/predicting-post-stroke-cognitive-impairment-using-electronic-health-record-data
#6
JOURNAL ARTICLE
Jeffrey M Ashburner, Yuchiao Chang, Bianca Porneala, Sanjula D Singh, Nirupama Yechoor, Jonathan M Rosand, Daniel E Singer, Christopher D Anderson, Steven J Atlas
BACKGROUND: Secondary prevention interventions to reduce post-stroke cognitive impairment (PSCI) can be aided by the early identification of high-risk individuals who would benefit from risk factor modification. AIMS: To develop and evaluate a predictive model to identify patients at increased risk of PSCI over 5 years using data easily accessible from electronic health records. METHODS: Cohort study that included primary care patients from two academic medical centers...
March 28, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/38545735/early-detection-of-nasopharyngeal-carcinoma-through-machine-learning-driven-prediction-model-in-a-population-based-healthcare-record-database
#7
JOURNAL ARTICLE
Jeng-Wen Chen, Shih-Tsang Lin, Yi-Chun Lin, Bo-Sian Wang, Yu-Ning Chien, Hung-Yi Chiou
OBJECTIVE: Early diagnosis and treatment of nasopharyngeal carcinoma (NPC) are vital for a better prognosis. Still, because of obscure anatomical sites and insidious symptoms, nearly 80% of patients with NPC are diagnosed at a late stage. This study aimed to validate a machine learning (ML) model utilizing symptom-related diagnoses and procedures in medical records to predict nasopharyngeal carcinoma (NPC) occurrence and reduce the prediagnostic period. MATERIALS AND METHODS: Data from a population-based health insurance database (2001-2008) were analyzed, comparing adults with and without newly diagnosed NPC...
April 2024: Cancer Medicine
https://read.qxmd.com/read/38545589/forequarter-amputation-for-malignant-tumours-tale-of-sustained-relevance-or-telltale-sign-of-doom
#8
JOURNAL ARTICLE
Mudasir Bashir Dar, Gaurav Das
Forequarter amputation (interscapulothoracic amputation) includes surgical removal of an upper limb and the shoulder girdle, including the scapula and a portion of the clavicle. We aim to report about our recent experience of having to resort to this mutilating surgery and the clinicopathological variables in that context. The study was done at a cancer centre in Northeast India. It was an ambispective study design, where the patient cohort who underwent FQA was identified retrospectively from the operative register of major surgeries for the time period 1st June 2020 to 31st May 2022 (24 months), and these patients were followed up prospectively from 1st June 2022 to 31st May 2023 (1 year)...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545037/association-of-epicardial-fat-volume-with-subclinical-myocardial-damage-in-patients-with-type-2-diabetes-mellitus
#9
JOURNAL ARTICLE
Yurui Hu, Wenji Yu, Feifei Zhang, Yufeng Wang, Jingwen Wang, Peng Wan, Xiaoliang Shao, Jianfeng Wang, Yonghong Sun, Yuetao Wang
BACKGROUND: In type 2 diabetes mellitus (T2DM) patients, left ventricular systolic dyssynchrony (LVSD) with normal left ventricular ejection fraction (LVEF) and normal myocardial perfusion could referred to as subclinical myocardial damage, which is difficult to diagnose at an early stage. Epicardial adipose tissue, a distinctive heart-specific visceral fat, is closely related to various cardiovascular diseases. The objective of this study was to investigate the correlation between epicardial fat volume (EFV) and subclinical myocardial damage in T2DM patients...
March 15, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38544748/identifying-incarceration-status-in-the-electronic-health-record-using-large-language-models-in-emergency-department-settings
#10
JOURNAL ARTICLE
Thomas Huang, Vimig Socrates, Aidan Gilson, Conrad Safranek, Ling Chi, Emily A Wang, Lisa B Puglisi, Cynthia Brandt, R Andrew Taylor, Karen Wang
BACKGROUND: Incarceration is a significant social determinant of health, contributing to high morbidity, mortality, and racialized health inequities. However, incarceration status is largely invisible to health services research due to inadequate clinical electronic health record (EHR) capture. This study aims to develop, train, and validate natural language processing (NLP) techniques to more effectively identify incarceration status in the EHR. METHODS: The study population consisted of adult patients (≥ 18 y...
2024: Journal of Clinical and Translational Science
https://read.qxmd.com/read/38544646/prescribing-patterns-of-psychotropic-medications-for-common-psychiatric-disorders-in-a-mental-health-hospital-in-tabuk
#11
JOURNAL ARTICLE
Mostafa A Ali, Palanisamy Amirthalingam, Vinoth-Prabhu Veeramani, Abdulmajeed M Alasiri, Meshal N Alsalimi, Fahad Alatawi, Mutlaq M Albalawi
INTRODUCTION: Mental health disorders are often chronic and disabling conditions that impact different populations, irrespective of age, cultural background, or socioeconomic status. This study aimed to describe the prescribing pattern of psychotropic medications in patients with psychiatric disorders. METHODS: This research was a retrospective investigation of psychotropic medication prescribing patterns and conducted at Eradah Mental Health Hospital at Tabuk City, Saudi Arabia...
February 2024: Curēus
https://read.qxmd.com/read/38544555/retrospective-study-of-the-impact-of-diabetes-on-the-severity-and-prognosis-of-covid%C3%A2-19
#12
JOURNAL ARTICLE
Lijun Sun, Xiaoli Yang, Bowei Cao, Xiaodong Su, Jianhua Wang, Cuixiang Xu
Patients with diabetes coexisting with viral infection tend to have poor outcomes, but the association between diabetes and coronavirus disease 2019 (COVID-19) prognosis is controversial at present. The present study reviewed and analyzed the data of 1,892 patients with COVID-19 admitted to Shaanxi Provincial People's Hospital (Xi'an, China). Demographic, clinical, laboratory and treatment data as well as clinical outcomes were extracted from the electronic medical records and compared between patients with and without diabetes...
May 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38543904/prolonged-sars-cov-2-t-cell-responses-in-a-vaccinated-covid-19-naive-population
#13
JOURNAL ARTICLE
Vassiliki C Pitiriga, Myrto Papamentzelopoulou, Kanella E Konstantinakou, Irene V Vasileiou, Alexandros D Konstantinidis, Natalia I Spyrou, Athanasios Tsakris
INTRODUCTION: Exploring T cell response duration is pivotal for understanding immune protection evolution in natural SARS-CoV-2 infections. The objective of the present study was to analyze the T cell immune response over time in individuals who were both vaccinated and COVID-19-naive and had undetectable levels of SARS-CoV-2 IgG antibodies at the time of testing. METHODS: We performed a retrospective descriptive analysis using data extracted from the electronic medical records of consecutive adult individuals who underwent COVID-19 immunity screening at a private healthcare center from September 2021 to September 2022...
March 4, 2024: Vaccines
https://read.qxmd.com/read/38543226/advancing-precision-medicine-a-review-of-innovative-in-silico-approaches-for-drug-development-clinical-pharmacology-and-personalized-healthcare
#14
REVIEW
Lara Marques, Bárbara Costa, Mariana Pereira, Abigail Silva, Joana Santos, Leonor Saldanha, Isabel Silva, Paulo Magalhães, Stephan Schmidt, Nuno Vale
The landscape of medical treatments is undergoing a transformative shift. Precision medicine has ushered in a revolutionary era in healthcare by individualizing diagnostics and treatments according to each patient's uniquely evolving health status. This groundbreaking method of tailoring disease prevention and treatment considers individual variations in genes, environments, and lifestyles. The goal of precision medicine is to target the "five rights": the right patient, the right drug, the right time, the right dose, and the right route...
February 27, 2024: Pharmaceutics
https://read.qxmd.com/read/38543181/digital-technology-applications-in-the-management-of-adverse-drug-reactions-bibliometric-analysis
#15
JOURNAL ARTICLE
Olena Litvinova, Andy Wai Kan Yeung, Fabian Peter Hammerle, Michel-Edwar Mickael, Maima Matin, Maria Kletecka-Pulker, Atanas G Atanasov, Harald Willschke
Adverse drug reactions continue to be not only one of the most urgent problems in clinical medicine, but also a social problem. The aim of this study was a bibliometric analysis of the use of digital technologies to prevent adverse drug reactions and an overview of their main applications to improve the safety of pharmacotherapy. The search was conducted using the Web of Science database for the period 1991-2023. A positive trend in publications in the field of using digital technologies in the management of adverse drug reactions was revealed...
March 19, 2024: Pharmaceuticals
https://read.qxmd.com/read/38541930/effect-of-sex-age-and-cardiovascular-risk-factors-on-aortoiliac-segment-geometry
#16
JOURNAL ARTICLE
Ádám Szőnyi, György Balázs, Balázs Bence Nyárády, Márton Philippovich, Tamás Horváth, Edit Dósa
Background: To investigate the geometry of the aortoiliac (AI) segment and its correlation with sex, age, and cardiovascular (CV) risk factors. Methods: Abdominal and pelvic CTA/MRA scans of 204 subjects (120 males; median age: 53 [IQR, 27-75] years) without AI steno-occlusive disease or scoliosis were retrospectively analyzed. The participants were enrolled consecutively, ensuring the representation of each age decade. An in-house written software was developed to assess AI elongation using the tortuosity index (TI) and absolute average curvature (AAC)...
March 15, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541927/covid-19-influenza-and-rsv-in-children-and-adults-a-clinical-comparative-study-of-12-000-cases
#17
JOURNAL ARTICLE
Jae-Hyun Kwon, So-Hyun Paek, Soo-Hyun Park, Min-Jung Kim, Young-Hoon Byun, Ho-Young Song
(1) Background: Respiratory virus infections, including Coronavirus disease 2019 (COVID-19), seasonal influenza (FLU), and respiratory syncytial virus (RSV) as prominent examples, can severely affect both children and adults. This study aimed to investigate the clinical characteristics of respiratory viral infections in pediatric and adult populations and to identify determinants influencing patient hospitalization. (2) Methods: This retrospective study analyzed the electronic medical records of patients admitted to a regional hospital's emergency department from 1 January 2015 to 31 December 2022, to investigate the clinical characteristics and hospitalization risk factors associated with these three viruses...
March 15, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541903/quality-improvement-protocol-improving-the-use-of-nonpharmacological-pain-management-strategies-within-the-inpatient-hospital-setting
#18
JOURNAL ARTICLE
Katherine S Salamon, Christina Russell, Dara DeVinney, Catherine M Soprano
Background: There are many nonpharmacological pain management services available to hospitalized youth; however, not all youth are offered these services. Lack of knowledge about resources, difficulty with the referral process, and lack of understanding about nonpharmacological pain management services and when to refer patients are among the main reasons for lack of utilization. Quality improvement (QI) initiatives have grown within hospital settings and can serve to create change in fast-paced environments...
March 14, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541773/clinical-and-radiological-characteristics-of-non-obese-female-patients-with-idiopathic-intracranial-hypertension
#19
JOURNAL ARTICLE
Anat Horev, Gal Ben-Arie, Yair Zlotnik, Maor Koltochnik, Or Ben Chaim, Ron Biederko, Tamir Regev, Erez Tsumi, Ilan Shelef, Yana Mechnik Steen, Tal Eliav, Mark Katson, Erel Domany, Asaf Honig
While the typical patient with idiopathic intracranial hypertension (IIH) is an obese female of childbearing age, there are unique patient populations, such as non-obese females, that have not been well studied. Characterizing this subpopulation may increase awareness our of it, which may prevent underdiagnosis and improve our understanding of IIH's underlying pathophysiology. We retrospectively reviewed electronic medical records and compared the clinical and radiological characteristics of non-obese (BMI < 30) and obese (BMI > 30) female patients with IIH...
March 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541663/angioleiomyoma-an-update-with-a-142-case-series
#20
JOURNAL ARTICLE
Mathilde Bernard, Louis-Romée Le Nail, Gonzague de Pinieux, Ramy Samargandi
Angioleiomyomas are uncommon, noncancerous, smooth muscle tumors that primarily arise from blood vessels. Previous studies have yielded limited data due to the lack of interdisciplinary approaches or restricted patient pools. This study aims to provide a comprehensive analysis of angioleiomyomas, including the demographic, clinical, radiological, and histopathological features, with a large number of patients. Conducted as a retrospective investigation at a single center from January 2005 to June 2023, this study involved 142 patients...
March 4, 2024: Life
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