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https://www.readbyqxmd.com/read/27908251/effects-of-an-outpatient-service-rehabilitation-programme-in-patients-affected-by-pulmonary-arterial-hypertension-an-observational-study
#1
Maurizio Bussotti, Paola Gremigni, Roberto Fe Pedretti, Patrycja Kransinska, Silvia Di Marco, Paola Corbo, Giovanni Marchese, Paolo Totaro, Marinella Sommaruga
BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare disease characterised by a severe impairment of functional status and quality of life (QoL). Use of rehabilitative programmes may help to improve outcomes. The aim of this pre/post test case series was to evaluate the impact of a training program, including sessions of aerobic and resistance exercise, inspiratory muscle reinforcement, slow breathing, relaxation, and psychological support, on functional outcomes. METHODS: Fifteen patients affected by PAH, in World Health Organization (WHO) Functional Class (FC) II or III and in stable clinical condition, were included in a 4-week cardiorespiratory training programme conducted in outpatient service...
November 30, 2016: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/27903669/exertional-dyspnoea-in-obesity
#2
Vipa Bernhardt, Tony G Babb
The purpose of cardiopulmonary exercise testing (CPET) in the obese person, as in any cardiopulmonary exercise test, is to determine the patient's exercise tolerance, and to help identify and/or distinguish between the various physiological factors that could contribute to exercise intolerance. Unexplained dyspnoea on exertion is a common reason for CPET, but it is an extremely complex symptom to explain. Sometimes obesity is the simple answer by elimination of other possibilities. Thus, distinguishing among multiple clinical causes for exertional dyspnoea depends on the ability to eliminate possibilities while recognising response patterns that are unique to the obese patient...
December 2016: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/27899540/the-1-minute-sit-to-stand-test-in-adults-with-cystic-fibrosis-correlations-with-cardiopulmonary-exercise-test-6-minute-walk-test-and-quadriceps-strength
#3
Mathieu Gruet, Leonardo Alexandre Peyré-Tartaruga, Laurent Mely, Jean-Marc Vallier
BACKGROUND: Exercise testing is part of the regular assessment of patients with cystic fibrosis (CF). We aimed to evaluate (1) the convergent validity of the 1-min sit-to-stand (STS) test in CF by investigating its relationships with peak oxygen uptake (peak V̇O2 ), quadriceps strength, and quality of life and (2) to compare these associations with those of the 6-min walk test (6MWT). METHODS: Twenty-five adults with CF (FEV1 = 59 ± 24%) performed the STS test, the 6MWT, quadriceps strength assessment, and cardiopulmonary exercise test (CPET)...
December 2016: Respiratory Care
https://www.readbyqxmd.com/read/27884421/interpreting-the-incremental-cardiopulmonary-exercise-test
#4
REVIEW
Samir Nusair
The incremental cardiopulmonary exercise test (CPET) is an increasingly used diagnostic method that serves to evaluate patients with chief complaint of dyspnea during exercise. Performing maximal symptom-limited CPET can show if the tested subject has a reduced exercise capacity and give clues to the mechanism of such exercise capacity reduction, cardiac, pulmonary, or pulmonary vascular source. In this review, it is suggested that the evaluation of the complex results of CPET should be performed by first determining if myocardial/circulatory insufficiency is present and second if there is gas exchange abnormality...
November 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27878634/relationship-between-habitual-exercise-and-performance-on-cardiopulmonary-exercise-testing-differs-between-children-with-single-and-biventricular-circulations
#5
Michael L O'Byrne, Sanyukta Desai, Megan Lane, Michael McBride, Stephen Paridon, Elizabeth Goldmuntz
Increasing habitual exercise has been associated with improved cardiopulmonary exercise testing (CPET) performance, specifically maximal oxygen consumption in children with operatively corrected congenital heart disease. This has not been studied in children following Fontan palliation, a population in whom CPET performance is dramatically diminished. A single-center cross-sectional study with prospective and retrospective data collection was performed that assessed habitual exercise preceding a clinically indicated CPET in children and adolescents with Fontan palliation, transposition of the great arteries following arterial switch operation (TGA), and normal cardiac anatomy without prior operation...
November 23, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27875636/evaluation-of-coronary-artery-disease-in-potential-liver-transplant-recipients
#6
REVIEW
Brian J Hogan, Enoka Gonsalkorala, Michael A Heneghan
Improvements in the management of patients undergoing Liver Transplantation (LT) have resulted in a significant increase in survival over recent years. Cardiac disease is now the leading cause of early mortality and the stress of major surgery, haemodynamic shifts, the possibility of haemorrhage or reperfusion syndrome require the recipient to have good baseline cardiac function. The prevalence of coronary artery disease (CAD) is increasing in liver transplant candidates, especially in those with Non-Alcohol related Fatty Liver Disease (NAFLD)...
November 22, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27863351/abnormal-heart-rate-response-during-cardiopulmonary-exercise-testing-identifies-cardiac-dysfunction-in-symptomatic-patients-with-non-obstructive-coronary-artery-disease
#7
Sundeep Chaudhry, Naresh Kumar, Hushyar Behbahani, Akshay Bagai, Binoy K Singh, Nick Menasco, Gregory D Lewis, Laurence Sperling, Jonathan Myers
BACKGROUND: Symptomatic non-obstructive coronary artery disease is a growing clinical dilemma for which contemporary testing is proving to be of limited clinical utility. New methods are needed to identify cardiac dysfunction. METHODS AND RESULTS: This is a prospective observational cohort study conducted from December 2013 to August 2015 in two outpatient cardiology clinics (symptomatic cohort) and 24 outpatient practices throughout the US (healthy cohort) with centralized methodology and monitoring to compare heart-rate responses during cardiopulmonary exercise testing (CPET)...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27853765/efficient-oxygen-evolution-on-hematite-at-neutral-ph-enabled-by-proton-coupled-electron-transfer
#8
Toshihiro Takashima, Koki Ishikawa, Hiroshi Irie
The rate-determining step of the oxygen evolution reaction on hematite electrodes was switched from the sequential electron/proton transfer process to the concerted proton-coupled electron transfer (CPET) process by adding pyridine derivatives to the electrolyte. By inducing the CPET process, the overpotential for oxygen evolution at neutral pH decreased by approximately 250 mV.
November 17, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27794485/non-invasive-ventilation-before-maximum-exercise-test-increases-exercise-tolerance-in-subjects-with-heart-failure-a-crossover-study
#9
Larissa de Andrade Carvalho, Daniella Cunha Brandão, Tainá Maria de Souza Vidal, Maria Inês Remígio, Sílvia Marinho, Armèle Dornelas de Andrade
OBJECTIVES: To evaluate the effect of non-invasive ventilation (NIV) on exercise performance in individuals with heart failure (HF). DESIGN: Crossover, randomized, blind clinical trial with allocation concealment. SETTING: University-based research laboratory. PARTICIPANTS: 8 women and 16 men with New York Heart Association class II-III left heart failure between the ages of 51.8 ± 10.2 years. INTERVENTIONS: Ventilatory support was administered at two pressure levels for 30 minutes attached to the face of the individual via a facemask prior to Cardiopulmonary Exercise Test (CPET)...
October 26, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27772769/cardiovascular-dysfunction-in-untreated-parkinson-s-disease-a-multi-modality-assessment
#10
Stefano Strano, Alessandra Fanciulli, Massimiliano Rizzo, Paolo Marinelli, Paolo Palange, Dorina Tiple, Giuseppe De Vincentis, Giovanni Calcagnini, Federica Censi, Giuseppe Meco, Carlo Colosimo
BACKGROUND: The clinical presentation of Parkinson's disease (PD) includes a wide spectrum of non-motor features, including cardiovascular autonomic failure. OBJECTIVE: To evaluate cardiovascular autonomic status and cardiac functional capacity in drug-naïve PD patients. METHODS: 18 newly-diagnosed PD patients underwent laboratory cardiovascular autonomic function tests using power spectral analysis of the R-R interval, blood pressure (BP) short-term variability and non-invasive baroreflex sensitivity (BRS)...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27748468/cardiopulmonary-exercise-testing-in-systolic-heart-failure-from-basic-to-advanced-practice
#11
Ugo Corrà
Cardiopulmonary exercise testing (CPET) is a specialized subtype of exercise testing that provides a more accurate and objective measure of cardiorespiratory fitness (CRF). CPET relies on measurement of ventilatory gases during exercise, i.e., a non-invasive procedure that involves the acquisition of expired ventilation and concentrations of oxygen (O2) and carbon dioxide (CO2) during progressive exercise. The non-invasive measurement of ventilation and expired gases permits the most accurate and reproducible quantification of CRF, a grading of the etiology and severity of impairment, and an objective assessment of the response to an intervention...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27748332/implementation-of-a-pediatric-emergency-triage-system-in-xiamen-china
#12
Gang-Xi Lin, Yin-Ling Yang, Denise Kudirka, Colleen Church, Collin K K Yong, Fiona Reilly, Qi-Yi Zeng
BACKGROUND: Pediatric emergency rooms (PERs) in Chinese hospitals are perpetually full of sick and injured children because of the lack of sufficiently developed community hospitals and low access to family physicians. The aim of this study was to evaluate the clinical value of a new five-level Chinese pediatric emergency triage system (CPETS), modeled after the Canadian Triage System and Acuity Scale. METHODS: In this study, we compared CPETS outcomes in our PER relative to those of the prior two-level system...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27744563/detection-of-exercise-periodic-breathing-using-thermal-flowmeter-in-patients-with-heart-failure
#13
Tieh-Cheng Fu, Wen-Chen Lin, Jong-Shyan Wang, Chao-Hung Wang, Chun-Tien Chang, Cheng-Lun Tsai, Yun-Shien Lee, Kang-Ping Lin
Exercise periodic breathing (EPB) is associated with exercise intolerance and poor prognosis in patients with heart failure (HF). However, EPB detection during cardiopulmonary exercise test (CPET) is difficult. The present study investigated the use of a wireless monitoring device to record the EPB during CPET and proposed quantization parameter estimates for the EPB. A total of 445 patients with HF were enrolled and underwent exercise tests. The ventilation data from the wearable device were compared with the data obtained during the CPET and were analyzed based on professional opinion and on 2 automated programs (decision tree [DT] and oscillatory pattern methods)...
October 15, 2016: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/27742182/discriminating-circulatory-problems-from-deconditioning-echocardiogram-and-cardio-pulmonary-exercise-test-analysis
#14
Zach Rozenbaum, Shafik Khoury, Galit Aviram, Yaniv Gura, Jack Sherez, Avi Man, Jason Shimiaie, Thierry Le Tourneau, Amir Halkin, Simon Biner, Gad Keren, Yan Topilsky
BACKGROUND: Discriminating circulatory problems with reduced stroke volume from de-conditioning in which the muscles cannot consume O2 normally by gas exchange parameters is difficult. METHODS: We performed combined stress echo and cardio-pulmonary (CPET) tests in 110 patients (20 normal effort capacity, 54 attenuated stroke volume response, 36 de-conditioning) to evaluate multiple hemodynamic parameters and oxygen content difference (A-VO2 Difference) in four predefined activity levels to assess which of the gas measures may help in the discrimination...
October 11, 2016: Chest
https://www.readbyqxmd.com/read/27736721/functional-parameters-but-not-heart-rate-variability-correlate-with-long-term-outcomes-in-st-elevation-myocardial-infarction-patients-treated-by-primary-angioplasty
#15
Leonida Compostella, Nenad Lakusic, Nicola Russo, Tiziana Setzu, Caterina Compostella, Elia Vettore, Giambattista Isabella, Giuseppe Tarantini, Sabino Iliceto, Fabio Bellotto
BACKGROUND: Depressed heart rate variability (HRV) is usually considered a negative long-term prognostic factor after acute myocardial infarction. Anyway, most of the supporting research was conducted before the era of immediate reperfusion by percutaneous coronary intervention (PCI). Main aim of this study was to evaluate if HRV still retains prognostic significance in our era of immediate PCI. METHODS AND RESULTS: Two weeks after STEMI treated by primary PCI, time-domain HRV was assessed from 24-h Holter recordings in 186 patients: markedly depressed HRV (SDNN <70ms or <50ms) was present in 16% and in 5% of cases, respectively; patients with left ventricle ejection fraction (LVEF) <40% presented more often SDNN values in the lowest quartile...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27721367/a-pair-of-identical-twins-discordant-for-myalgic-encephalomyelitis-chronic-fatigue-syndrome-differ-in-physiological-parameters-and-gut-microbiome-composition
#16
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27715378/relationship-between-the-sensation-of-activity-limitation-and-the-results-of-functional-assessment-in-asthma-patients
#17
Francois Vermeulen, Audrey Chirumberro, Peter Rummens, Marie Bruyneel, Vincent Ninane
OBJECTIVE: In asthma patients, the assessment of activity limitation is based on questions evaluating how limited the patient feels in their activities. However, the lack of functional data complicates the interpretation of the answers. We aimed to evaluate the intensity of relationships between the patient's perception of activity limitation and the results of several functional tests. METHODS: Twenty patients complaining of asthma exacerbation were invited to complete three scores (Chronic Respiratory Disease questionnaire, Asthma Control Questionnaire, Hospital Anxiety and Depression scale)...
October 7, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27711026/preoperative-functional-assessment-and-optimization-in-surgical-patient-changing-the-paradigm
#18
Francesco Carli, Enrico M Minnella
Functional capacity has been shown to be a major determinant of surgical outcome since it is related to postoperative complications, activity and daily function, level of independence and quality of life. Anesthesiologists as "perioperative physicians", can identify those scoring systems that assess functional capacity, whether from the basic physical history and walk test to the most complex such as cardiopulmonary exercise testing (CPET), and formulate intraoperative and postoperative interventions (rehabilitation) to minimize the impact of surgery on the recovery process...
October 6, 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/27692931/heart-failure-and-anemia-effects-on-prognostic-variables
#19
Gaia Cattadori, Piergiuseppe Agostoni, Ugo Corrà, Gianfranco Sinagra, Fabrizio Veglia, Elisabetta Salvioni, Alice Bonomi, Rocco La Gioia, Angela B Scardovi, Alessandro Ferraironi, Michele Emdin, Marco Metra, Andrea Di Lenarda, Giuseppe Limongelli, Rosa Raimondo, Federica Re, Marco Guazzi, Romualdo Belardinelli, Gianfranco Parati, Sergio Caravita, Damiano Magrì, Carlo Lombardi, Maria Frigerio, Fabrizio Oliva, Davide Girola, Alessandro Mezzani, Stefania Farina, Massimo Mapelli, Domenico Scrutinio, Giuseppe Pacileo, Anna Apostolo, AnnaMaria Iorio, Stefania Paolillo, Pasquale Perrone Filardi, Paola Gargiulo, Maurizio Bussotti, Giovanni Marchese, Michele Correale, Roberto Badagliacca, Susanna Sciomer, Pietro Palermo, Mauro Contini, Pantaleo Giannuzzi, Elisa Battaia, Mariantonietta Cicoira, Francesco Clemenza, Chiara Minà, Simone Binno, Claudio Passino, Massimo F Piepoli
BACKGROUND: Anemia is frequent in heart failure (HF), and it is associated with higher mortality. The predictive power of established HF prognostic parameters in anemic HF patients is unknown. METHODS: Clinical, laboratory, echocardiographic and cardiopulmonary-exercise-test (CPET) data were analyzed in 3913 HF patients grouped according to hemoglobin (Hb) values. 248 (6%), 857 (22%), 2160 (55%) and 648 (17%) patients had very low (<11g/dL), low (11-12 for females, 11-13 for males), normal (12-15 for females, 13-15 for males) and high (>15) Hb, respectively...
September 28, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27669015/adrenergic-receptor-polymorphism-and-maximal-exercise-capacity-after-orthotopic-heart-transplantation
#20
Mélanie Métrich, Fortesa Mehmeti, Helene Feliciano, David Martin, Julien Regamey, Piergiorgio Tozzi, Philippe Meyer, Roger Hullin
BACKGROUND: Maximal exercise capacity after heart transplantion (HTx) is reduced to the 50-70% level of healthy controls when assessed by cardiopulmonary exercise testing (CPET) despite of normal left ventricular function of the donor heart. This study investigates the role of donor heart β1 and β2- adrenergic receptor (AR) polymorphisms for maximal exercise capacity after orthotopic HTx. METHODS: CPET measured peak VO2 as outcome parameter for maximal exercise in HTx recipients ≥9 months and ≤4 years post-transplant (n = 41; mean peak VO2: 57±15% of predicted value)...
2016: PloS One
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