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https://www.readbyqxmd.com/read/28106128/fabrication-of-au-ag-nanocage-nayf4-nayf4-yb-er-core-shell-hybrid-and-its-tunable-upconversion-enhancement
#1
Xu Chen, Donglei Zhou, Wen Xu, Jinyang Zhu, Gencai Pan, Ze Yin, He Wang, Yongsheng Zhu, Cui Shaobo, Hongwei Song
Localized electric filed enhancement by surface plasmon resonance (SPR) of noble metal nanoparticles is an effective method to amplify the upconversion luminescence (UCL) strength of upconversion nanoparticles (UCNPs), whereas the highly effective UCL enhancement of UCNPs in colloids has not been realized until now. Here, we designed and fabricated the colloidal Au-Ag nanocage@NaYF4@NaYF4:Yb,Er core-shell hybrid with different intermediate thickness (NaYF4) and tunable SPR peaks from visible wavelength region to NIR region...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28104091/major-league-pitching-workload-after-primary-ulnar-collateral-ligament-reconstruction-and-risk-for-revision-surgery
#2
Robert A Keller, Nima Mehran, Nathan E Marshall, Kelechi R Okoroha, Lafi Khalil, James E Tibone, Vasilios Moutzouros
BACKGROUND: Literature has attempted to correlate pitching workload with risk of ulnar collateral ligament (UCL) injury; however, limited data are available in evaluating workload and its relationship with the need for revision reconstruction in Major League Baseball (MLB) pitchers. METHODS: We identified 29 MLB pitchers who underwent primary UCL reconstruction surgery and subsequently required revision reconstruction and compared them with 121 MLB pitchers who underwent primary reconstruction but did not later require revision surgery...
February 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28098706/current-trends-in-ulnar-collateral-ligament-reconstruction-surgery-among-newly-trained-orthopaedic-surgeons
#3
Ryan M Degen, Christopher L Camp, Johnathan A Bernard, David M Dines, David W Altchek, Joshua S Dines
INTRODUCTION: Ulnar collateral ligament (UCL) reconstructions are being performed with an increasing annual incidence. The purpose of this study was to evaluate trends in UCL surgery among recently trained orthopaedic surgeons. METHODS: The American Board of Orthopaedic Surgeons (ABOS) database was used to identify all UCL reconstructions from 2004 to 2013. Procedures were identified by Current Procedural Terminology (CPT) codes and verified by International Classification of Disease, Ninth Revision (ICD-9) codes...
February 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28098332/revisiting-the-optimized-doping-ratio-in-core-shell-nanostructured-upconversion-particles
#4
Bin Shen, Shengming Cheng, Yuyang Gu, Danrui Ni, Yilin Gao, Qianqian Su, Wei Feng, Fuyou Li
The development of rare-earth doped upconversion nanoparticles (RE-UCNPs) in various applications is fuelling the demand for nanoparticles with highly enhanced upconversion luminescence (UCL). Although the core/shell structure is proved to enhance the UCL effectively, there is still plenty of room to further improve the UCL by optimizing the doping ratio of the materials. In this article, a general strategy is demonstrated to achieve highly-enhanced visible UCL in core/shell nanostructured NaREF4 by increasing the doping ratio of Yb(3+) in the core region...
January 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28096168/sk-channel-enhancers-attenuate-ca2-dependent-arrhythmia-in-hypertrophic-hearts-by-regulating-mito-ros-dependent-oxidation-and-activity-of-ryr
#5
Tae Yun Kim, Radmila Terentyeva, Karim H F Roder, Weiyan Li, Man Liu, Ian Greener, Shanna Hamilton, Iuliia Polina, Kevin R Murphy, Richard T Clements, Samuel C Dudley, Gideon Koren, Bum-Rak Choi, Dmitry Terentyev
AIM: s: Plasmamembrane small conductance Ca<su2+p>-activated K<su+ p > (SK) channels were implicated in ventricular arrhythmias in infarcted and failing hearts. Recently, SK channels were detected in the mitochondria inner membrane (mSK), and their activation protected from acute ischemia-reperfusion injury by reducing intracellular levels of reactive oxygen species (ROS). We hypothesized that mSK play an important role in regulating mitochondrial function in chronic cardiac diseases...
January 17, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28087165/radiographic-comparison-of-adolescent-athletes-with-elbow-osteochondritis-dissecans-to-ulnar-collateral-ligament-injuries-and-controls
#6
Brian C Lau, Nirav K Pandya
BACKGROUND: There are excellent data supporting recommendations to prevent elbow injuries (osteochondritis dissecans [OCD] and ulnar collateral ligament [UCL] injuries), such as pitch count and pitch type in baseball, but anatomic risk factors have not been thoroughly examined. This study aimed to evaluate radiographic measurements in adolescents with elbow OCD lesions or UCL injuries and controls. METHODS: We retrospectively identified adolescent patients between 2011 and 2016 with isolated capitellum OCD, UCL tear, or normal elbows based on magnetic resonance imaging...
January 10, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28073756/feature-selection-using-a-one-dimensional-na%C3%A3-ve-bayes-classifier-increases-the-accuracy-of-support-vector-machine-classification-of-cdr3-repertoires
#7
Mattia Cinelli, Yuxin Sun, Katharine Best, James M Heather, Shlomit Reich-Zeliger, Eric Shifrut, Nir Friedman, John Shawe-Taylor, Benny Chain
MOTIVATION: Somatic DNA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. How this diversity captures antigen specificity remains incompletely understood. In this study we use high throughput sequencing to compare the global changes in T cell receptor β chain complementarity determining region 3 (CDR3β) sequences following immunization with ovalbumin administered with complete Freund's adjuvant (CFA) or CFA alone...
January 10, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28048706/tu-ab-bra-06-best-in-physics-joint-imaging-therapy-an-mri-compatible-externally-and-internally-deformable-lung-motion-phantom-for-multi-modality-igrt
#8
P Sabouri, T Arai, A Sawant
PURPOSE: MRI has become an attractive tool for tumor motion management. Current MR-compatible phantoms are only capable of reproducing translational motion. This study describes the construction and validation of a more realistic, MRI-compatible lung phantom that is deformable internally as well as externally. We demonstrate a radiotherapy application of this phantom by validating the geometric accuracy of the open-source deformable image registration software NiftyReg (UCL, UK). METHODS: The outer shell of a commercially-available dynamic breathing torso phantom was filled with natural latex foam with eleven water tubes...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048689/su-f-t-294-the-analysis-of-gamma-criteria-for-delta4-dosimetry-using-statistical-process-control
#9
S Cho, S Ahn, J Kim, K Park, W Choi, H Lee, E Lee, J Yoon, K Keum
PURPOSE: To evaluate the sensitivity of gamma criteria for patient-specific volumetric modulated arc therapy(VMAT) quality assurance of the Delta(4) dosimetry program using the statistical process control(SPC) methodology. METHODS: The authors selected 20 patient-specific VMAT QA cases which were undertaken MapCHECK and ArcCHECK with gamma pass rate better than 97%. The QAs data were collected Delta4 Phantom+ and Elekta Agility six megavolts without using an angle incrementer...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28039094/petpve12-an-spm-toolbox-for-partial-volume-effects-correction-in-brain-pet-application-to-amyloid-imaging-with-av45-pet
#10
Gabriel Gonzalez-Escamilla, Catharina Lange, Stefan Teipel, Ralph Buchert, Michel J Grothe
Positron emission tomography (PET) allows detecting molecular brain changes in vivo. However, the accuracy of PET is limited by partial volume effects (PVE) that affects quantitative analysis and visual interpretation of the images. Although PVE-correction methods have been shown to effectively increase the correspondence of the measured signal with the true regional tracer uptake, these procedures are still not commonly applied, neither in clinical nor in research settings. Here, we present an implementation of well validated PVE-correction procedures as a SPM toolbox, PETPVE12, for automated processing...
December 28, 2016: NeuroImage
https://www.readbyqxmd.com/read/28031709/magnetic-and-fluorescent-gd2o3-yb-3-ln-3-nanoparticles-for-simultaneous-upconversion-luminescence-mr-dual-modal-imaging-and-nir-induced-photodynamic-therapy
#11
Jun Liu, Long Huang, Xiumei Tian, Xiaoming Chen, Yuanzhi Shao, Fukang Xie, Dihu Chen, Li Li
The development of upconversion nanoparticles (UCNs) for theranostics application is a new strategy toward the accurate diagnosis and efficient treatment of cancer. Here, magnetic and fluorescent lanthanide-doped gadolinium oxide (Gd2O3) UCNs with bright upconversion luminescence (UCL) and high longitudinal relaxivity (r1) are used for simultaneous magnetic resonance imaging (MRI)/UCL dual-modal imaging and photodynamic therapy (PDT). In vitro and in vivo MRI studies show that these products can serve as good MRI contrast agents...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28027603/survival-implications-of-opioid-use-before-and-after-liver-transplantation
#12
Henry B Randall, Tarek Alhamad, Mark A Schnitzler, Zidong Zhang, Sophia Ford-Glanton, David A Axelrod, Dorry L Segev, Bertram L Kasiske, Gregory P Hess, Hui Yuan, Rosemary Ouseph, Krista L Lentine
BACKGROUND: Implications of prescription opioid use for outcomes after liver transplant have not been described. METHODS: We integrated national transplant registry data with records from a large pharmaceutical claims clearinghouse (2008-2014; n=26,925). Opioid fills on the waiting list were normalized to morphine equivalents (ME), and exposure was categorized as: >0 to 2 ME/day (level 1), >2 to 10 ME/day (level 2), >10 to 70 ME/day (level 3), and >70 ME/day (level 4)...
December 27, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/28005101/ulnar-collateral-ligament-reconstruction-current-philosophy-in-2016
#13
E Lyle Cain, Taylor P Mathis
The ulnar collateral ligament (UCL) is the primary static restraint to valgus stress at the elbow. Since Jobe pioneered reconstruction in 1974, thousands of throwers have undergone UCL reconstruction, and good results have been achieved. The high-profile nature of the elite pitcher has brought this technique into the spotlight, and extensive research has been performed with new techniques emerging. The standard reconstruction, modified only slightly since Jobe's original description, remains the gold standard for treatment of UCL insufficiency...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27990316/subthalamus-stimulation-in-parkinson-disease-accounting-for-the-bilaterality-of-contacts
#14
Jean-Jacques Lemaire, Bruno Pereira, Philippe Derost, François Vassal, Miguel Ulla, Dominique Morand, Guillaume Coll, Jean Gabrillargues, Ana Marques, Bérangère Debilly, Jérôme Coste, Franck Durif
BACKGROUND: Deep brain stimulation (DBS) in Parkinson's disease uses bi-hemispheric high-frequency stimulation within the subthalamus, however, the specific impacts of bilaterality of DBS are still not clear. Thus, we aimed to study the individual-level clinical impact of locations of right-left contact pair-up accounting for each subthalamic nucleus (STN) anatomy. METHODS: Contact locations and effects at 1 year were studied retrospectively in an unselected series of 53 patients operated between 2004 and 2010...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27968876/persistent-effects-of-parental-migration-on-psychosocial-wellbeing-of-left-behind-children-in-two-chinese-provinces-a-cross-sectional-survey
#15
Chenyue Zhao, Feng Wang, Leah Li, Xudong Zhou, Therese Hesketh
BACKGROUND: Lengthy separation from migrant parents raises concerns for the wellbeing of 60 million left-behind children (LBC) in rural China. This study aimed to investigate the effect of current and previous parental migration on the psychosocial wellbeing of left-behind children, and the mitigating or exacerbating factors in family care and support. METHODS: Children were recruited from schools by random stratified sampling in rural Zhejiang and Guizhou provinces where out-migration was high...
October 2016: Lancet
https://www.readbyqxmd.com/read/27951693/solvent-induced-luminescence-variation-of-upconversion-nanoparticles
#16
Tie Cong, Yadan Ding, Shuang Xin, Xia Hong, Hong Zhang, Yichun Liu
Solvent plays a vital role in the syntheses, purifications, and broad applications of upconversion nanoparticles (UCNPs). In this work, the effect of various dispersive solvents, including single solvents and mixed solvents, on the luminescence properties of NaYF4:Yb(3+), Er(3+) UCNPs was studied systematically. The differences in both upconversion luminescence (UCL) intensities and color outputs of the nanoparticles were observed when dispersing the UCNPs in deuterium oxide, dimethylformamide (DMF), dimethyl sulfoxide (DMSO), ethanol, or water...
December 13, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/27940806/treatment-for-ulnar-neuritis-around-the-elbow-in-adolescent-baseball-players-factors-associated-with-poor-outcome
#17
Masahiro Maruyama, Hiroshi Satake, Masatoshi Takahara, Mikio Harada, Tomohiro Uno, Nariyuki Mura, Michiaki Takagi
BACKGROUND: Ulnar neuritis around the elbow is one of the injuries seen in throwing athletes. Outcomes of nonsurgical treatment and factors associated with failure outcomes have not been reported. PURPOSE: To investigate the outcomes of treatments for ulnar neuritis in adolescent baseball players. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: We assessed 40 male baseball players with a mean age of 15.0 years (range, 13-17 years) who presented with ulnar neuritis...
December 9, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27929539/sensitivity-of-hematopoietic-stem-cells-to-mitochondrial-dysfunction-by-sdhd-gene-deletion
#18
José Antonio Bejarano-García, África Millán-Uclés, Iván V Rosado, Luís Ignacio Sánchez-Abarca, Teresa Caballero-Velázquez, María José Durán-Galván, José Antonio Pérez-Simón, José I Piruat
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to oxygen-limiting conditions. This adaptation includes suppression of mitochondrial activity, induction of anerobic glycolysis, and activation of hypoxia-inducible transcription factor 1α (Hif1α)-dependent gene expression. During progression of hematopoiesis, a metabolic switch towards mitochondrial oxidative phosphorylation is observed, making this organelle essential for determining cell fate choice in bone marrow...
December 8, 2016: Cell Death & Disease
https://www.readbyqxmd.com/read/27917796/does-tinnitus-lead-to-depression
#19
Esra Temugan, Rabia B Yildirım, Hümeyra Onat, Merve Susuz, Cemre Elden, Selim Unsal, Nebi Mustafa Gumus, Mesut Kaya
PURPOSE: The aim of the study was to investigate the correlation between THI (Tinnitus Handicap Inventory) and BDS (Beck Depression Scale). MATERIALS AND METHODS: High frequency thresholds and PTA (Pure Tone Audiometer) thresholds for the patients were measured in 44 patients with tinnitus (bilateral=13; unilateral=31). Tinnitus frequency and intensity were measured using one-pair method with high frequency audiometer Interacoustic AC40. Applied BDS and THI scores are evaluated for all patients...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27912956/further-comments-on-some-core-arguments-from-a-discussion-about-is-traditional-chinese-medicine-really-relevant
#20
Xiao Ye
A discussion on "Is traditional Chinese medicine (TCM) really relevant?" was held in the University College London (UCL) on the afternoon of 31st March, 2015. The author summarized some core viewpoints of the participants and then tried to focus on the opponent's opinions to clear up the arguments by illustrating respects of history, knowledge learning process, evidence based medicine (EBM) and strengths of TCM. This article will propose that the human health is extremely delicate and complicated and that no system of medicine can resolve all the problems of the human body...
December 2016: Complementary Therapies in Medicine
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