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https://www.readbyqxmd.com/read/29905016/examining-the-july-effect-on-patients-undergoing-pituitary-surgery
#1
Bassel Bashjawish, Shreya Patel, Suat Kılıç, Wayne D Hsueh, James K Liu, Soly Baredes, Jean Anderson Eloy
BACKGROUND: Our aim in this study was to assess the impact of the turnover of residents in July on patients undergoing pituitary surgery. METHODS: This work was a retrospective cohort study of cases from the National Inpatient Sample (NIS). Patients who underwent pituitary surgery from 2005 to 2012 were selected in the NIS. Patients undergoing surgery in July and in non-July months were compared to determine differences in demographics, comorbidities, and complications...
June 15, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29903680/-non-infective-endocarditis
#2
A Le Bot, P Jégo, E Donal, E Flécher, M Revest, P Tattevin
Non-infective endocarditis, also referred to as non-bacterial thrombotic endocarditis, represent a wide range of rare pathologies, often severe. This review gathered the data available in the literature, to decipher the major information collected on the pathophysiology, the diagnosis and the treatment of these heterogeneous diseases, often misdiagnosed. Characteristics of non-infective endocarditis are similar to infective endocarditis in terms of valvular lesions (mostly left-sided, with regurgitations and vegetations), and their complications (embolism)...
June 11, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29903028/feasibility-of-a-novel-synthetic-self-assembling-peptide-for-suture-line-haemostasis-in-cardiac-surgery
#3
Suresh Giritharan, Kareem Salhiyyah, Geoffrey M Tsang, Sunil K Ohri
BACKGROUD: To assess the feasibility and efficacy of PuraStat®, a novel haemostatic agent, in achieving suture line haemostasis in a wide range of cardiac surgical procedures and surgery of the thoracic aorta. METHODS: A prospective, non-randomised study was conducted at our institution. Operative data on fifty consecutive patients undergoing cardiac surgery where PuraStat® was utilised in cases of intraoperative suture line bleeding was prospectively collected...
June 15, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29900874/dabigatran-in-patients-with-myocardial-injury-after-non-cardiac-surgery-manage-an-international-randomised-placebo-controlled-trial
#4
P J Devereaux, Emmanuelle Duceppe, Gordon Guyatt, Vikas Tandon, Reitze Rodseth, Bruce M Biccard, Denis Xavier, Wojciech Szczeklik, Christian S Meyhoff, Jessica Vincent, Maria Grazia Franzosi, Sadeesh K Srinathan, Jason Erb, Patrick Magloire, John Neary, Mangala Rao, Prashant V Rahate, Navneet K Chaudhry, Bongani Mayosi, Miriam de Nadal, Pilar Paniagua Iglesias, Otavio Berwanger, Juan Carlos Villar, Fernando Botto, John W Eikelboom, Daniel I Sessler, Clive Kearon, Shirley Pettit, Mukul Sharma, Stuart J Connolly, Shrikant I Bangdiwala, Purnima Rao-Melacini, Andreas Hoeft, Salim Yusuf
BACKGROUND: Myocardial injury after non-cardiac surgery (MINS) increases the risk of cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran prevents perioperative venous thromboembolism, but whether this drug can prevent a broader range of vascular complications in patients with MINS is unknown. The MANAGE trial assessed the potential of dabigatran to prevent major vascular complications among such patients. METHODS: In this international, randomised, placebo-controlled trial, we recruited patients from 84 hospitals in 19 countries...
June 9, 2018: Lancet
https://www.readbyqxmd.com/read/29899199/clinical-outcomes-of-drug-coated-balloons-in-coronary-artery-disease-unsuitable-for-drug-eluting-stent-implantation
#5
Raisuke Iijima, Norihiro Kougame, Hidehiko Hara, Masao Moroi, Masato Nakamura
BACKGROUND: The aim of this study was to investigate whether drug-coated balloon (DCB) treatment is effective for de novo coronary lesions that are unsuitable for drug-eluting stent (DES) implantation.Methods and Results:This retrospective study included 118 de novo lesions that were not suitable for DES implantation. Of the lesions, 40% was treated because of very small vessel disease. Patients with planned non-cardiac surgery and at high bleeding risk were 3% and 19%, respectively, and lesions that easily develop stent fracture comprised 26%...
June 12, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29898146/outcomes-after-surgical-resection-of-primary-non-myxoma-cardiac-tumors
#6
Kamil Boyacıoğlu, Adnan Ak, Arzu Antal Dönmez, Burçin Çayhan, Mehmet Aksüt, Mehmet Altuğ Tunçer
OBJECTIVE: Primary cardiac tumors are rare lesions with different histological type. We reviewed our 17 years of experience in the surgical treatment and clinical results of primary non-myxoma cardiac tumors. METHODS: Between July 2000 and February 2017, 21 patients with primary cardiac tumor were surgically treated in our institution. The tumors were categorized as benign non-myxomas and malignants. Data including the demographic characteristics, details of the tumor histology and grading, cardiac medical and surgical history, surgical procedure of the patients were obtained from the hospital database...
March 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29897437/influence-of-a-history-of-cancer-on-long-term-cardiovascular-outcomes-after-coronary-stent-implantation-an-observation-from-coronary-revascularization-demonstrating-outcome-study-kyoto-registry-cohort-2
#7
Kenji Nakatsuma, Hiroki Shiomi, Takeshi Morimoto, Hirotoshi Watanabe, Yoshihisa Nakagawa, Yutaka Furukawa, Kazushige Kadota, Kenji Ando, Koh Ono, Satoshi Shizuta, Takeshi Kimura
Aims: To evaluate the influence of a history of cancer on clinical outcomes in coronary artery disease (CAD) patients who underwent percutaneous coronary intervention (PCI). Methods and Results: In the CREDO-Kyoto PCI/coronary bypass grafting (CABG) Registry Cohort-2, there were 12,180 CAD patients who received PCI with stents. There were 1109 patients with a history of cancer (cancer group), and 11,071 patients without cancer (non-cancer group). The cumulative 5-year incidences of cardiac death and heart failure (HF) hospitalization were significantly higher in the cancer group than in the non-cancer group (12...
April 20, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29895289/intravenous-morphine-versus-intravenous-paracetamol-after-cardiac-surgery-in-neonates-and-infants-a-study-protocol-for-a-randomized-controlled-trial
#8
Gerdien A Zeilmaker-Roest, Joost van Rosmalen, Monique van Dijk, Erik Koomen, Nicolaas J G Jansen, Martin C J Kneyber, Sofie Maebe, Greet van den Berghe, Dirk Vlasselaers, Ad J J C Bogers, Dick Tibboel, Enno D Wildschut
BACKGROUND: Morphine is worldwide the analgesic of first choice after cardiac surgery in children. Morphine has unwanted hemodynamic and respiratory side effects. Therefore, post-cardiac surgery patients may potentially benefit from a non-opioid drug for pain relief. A previous study has shown that intravenous (IV) paracetamol is effective and opioid-sparing in children after major non-cardiac surgery. The aim of the study is to test the hypothesis that intermittent IV paracetamol administration in children after cardiac surgery will result in a reduction of at least 30% of the cumulative morphine requirement...
June 13, 2018: Trials
https://www.readbyqxmd.com/read/29895166/time-to-expand-risk-evaluation-systems-for-cardiac-surgery-looking-beyond-physiological-parameters
#9
Pernille F Cromhout, Philip Moons, Lau C Thygesen, Samer Nashef, Sune Damgaard, Selina Kikkenborg Berg
Risk assessment in cardiac surgery traditionally consists of medical and physiological parameters. However, non-physiological factors have also been found to be predictive of poor outcomes following cardiac surgery. Therefore, the isolated focus on physiological parameters is questionable. This paper describes the emotional, behavioural, social and functional factors that have been established to play a role in outcomes following cardiac surgery. This forms a basis for future research, testing the value of these factors above and beyond the physiological parameters...
June 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29893791/trastuzumab-versus-observation-for-her2-non-amplified-early-breast-cancer-with-circulating-tumor-cells-eortc-90091-10093-big-1-12-treat-ctc-a-randomized-phase-2-trial
#10
M Ignatiadis, S Litière, F Rothe, S Riethdorf, C Proudhon, T Fehm, K Aalders, H Forstbauer, P Fasching, E Brain, P Vuylsteke, E Guardiola, R Lorenz, K Pantel, K Tryfonidis, W Janni, M Piccart, C Sotiriou, B Rack, J-Y Pierga
Background: Trastuzumab improves the outcome of women with HER2 positive breast cancer. We aimed to assess whether trastuzumab decreases the detection rate of Circulating Tumor Cells (CTCs) in women with high risk, HER2 non-amplified, early breast cancer. Patients and Methods: The EORTC 90091-10093 BIG 1-12 Treat CTC is a phase 2 trial, conducted in 70 hospitals and 6 CTC laboratories across 5 European countries. Patients with centrally confirmed HER2 non-amplified breast cancer and ≥1 centrally confirmed CTC per 15mL of blood by CellSearch® following surgery and (neo)adjuvant chemotherapy were randomized (1:1) to 6 cycles of trastuzumab intravenously versus 18 weeks of observation...
June 11, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29893681/conversion-of-atrial-fibrillation-after-cardiosurgical-procedures-by-vernakalant%C3%A2-as-an-atrial-repolarization-delaying-agent-arda
#11
Hannan Dalyanoglu, Arash Mehdiani, Jan Philipp Minol, Nihat Firat Sipahi, Hug Aubin, Udo Boeken, Alfred Müller, Hisaki Makimoto, Artur Lichtenberg, Bernhard Korbmacher
Postoperative, new-onset atrial fibrillation (POAF) is one of the most common complications after cardiosurgical procedures. Vernakalant has been reported to be effective in the conversion of POAF. The aim of this study was to evaluate the efficacy and safety of vernakalant for atrial fibrillation after cardiac operations, and to investigate predictors for the success of vernakalant treatment. Patients and Methods: Post-cardiac surgery patients with new-onset of atrial fibrillation (AF) were consecutively enrolled in this study...
May 25, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29886301/predictors-of-30-day-outcomes-in-octogenarians-with-traumatic-c2-fractures-undergoing-surgery
#12
John K Yue, Angel Ordaz, Ethan A Winkler, Hansen Deng, Catherine G Suen, John F Burke, Andrew K Chan, Geoffrey T Manley, Sanjay S Dhall, Phiroz E Tarapore
OBJECTIVE: Predictors of surgical outcomes following traumatic axis (C2) fractures in octogenarians remain undercharacterized. METHODS: Patients aged ≥80-years undergoing cervical spine surgery following traumatic C2 fractures were extracted from the National Sample Program of the National Trauma Data Bank (2003-2012). Outcomes include overall inpatient complications, individual complications >1% incidence, hospital length of stay (HLOS), discharge disposition, and mortality...
June 7, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29885979/initial-experience-and-early-results-of-mitral-valve-repair-with-cardiocel-pericardial-patch
#13
Anton Tomšič, Daniella D Bissessar, Thomas J van Brakel, Nina Ajmone Marsan, Robert J M Klautz, Meindert Palmen
PURPOSE: To assess the performance of a tissue engineering process-treated bovine pericardium patch (CardioCel) in the setting of reconstructive mitral valve surgery. DESCRIPTION: Between 3/2014 and 4/2016, 30 patients (57.2±14.3 years, 27% female) underwent mitral valve leaflet repair with a CardioCel patch. EVALUATION: Perioperative mortality was 7% (2 patients, non-graft-related). In 28 remaining patients, pre-discharge echocardiography demonstrated good repaired valve function...
June 7, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29885826/predictive-value-of-the-age-creatinine-and-ejection-fraction-acef-score-in-patients-with-acute-coronary-syndromes
#14
Barbara E Stähli, Manfred B Wischnewsky, Philipp Jakob, Roland Klingenberg, Slayman Obeid, Dik Heg, Lorenz Räber, Stephan Windecker, Marco Roffi, François Mach, Baris Gencer, David Nanchen, Peter Jüni, Ulf Landmesser, Christian M Matter, Thomas F Lüscher, Willibald Maier
BACKGROUND: This study sought to investigate the predictive value of the age, creatinine, and ejection fraction (ACEF) score in patients with acute coronary syndromes (ACS). The ACEF score (age/left ventricular ejection fraction +1 [if creatinine > 176 μmol/L]) has been established in patients evaluated for coronary artery bypass surgery. Data on its predictive value in all-comer ACS patients undergoing percutaneous coronary intervention are scarce. METHODS: A total of 1901 patients prospectively enrolled in the Swiss ACS Cohort were included in the analysis...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29884600/intracranial-haemorrhage-in-infective-endocarditis
#15
Erwan Salaun, Anissa Touil, Sandrine Hubert, Jean-Paul Casalta, Frédérique Gouriet, Emmanuelle Robinet-Borgomano, Emilie Doche, Nadia Laksiri, Caroline Rey, Cécile Lavoute, Sébastien Renard, Hervé Brunel, Anne-Claire Casalta, Julie Pradier, Jean-François Avierinos, Hubert Lepidi, Laurence Camoin-Jau, Alberto Riberi, Didier Raoult, Gilbert Habib
BACKGROUND: Although intracranial cerebral haemorrhage (ICH) complicating infective endocarditis (IE) is a critical clinical issue, its characteristics, impact, and prognosis remain poorly known. AIMS: To assess the incidence, mechanisms, risk factors and prognosis of ICH complicating left-sided IE. METHODS: In this single-centre study, 963 patients with possible or definite left-sided IE were included from January 2000 to December 2015. RESULTS: Sixty-eight (7%) patients had an ICH (mean age 57±13 years; 75% male)...
June 5, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29883654/the-maze-procedure-and-postoperative-pacemakers
#16
REVIEW
James L Cox, Niv Ad, Andrei Churyla, S Chris Malaisrie, Duc Thinh Pham, Jane Kruse, Olga Kislitsina, Patrick M McCarthy
BACKGROUND: There is concern that the right atrial lesions of the Maze procedure lead to more permanent pacemakers postoperatively and that they provide little therapeutic advantage over left atrial lesions alone. METHODS: A discussion of the pertinent anatomy related to atrial fibrillation and the performance of the Maze procedure, the potential ways that the specialized conduction system could theoretically be damaged by the procedure, non-procedure-related causes for increased postoperative pacemaker requirements, and the basis for the efficacy of the right atrial lesions of the Maze procedure are presented...
June 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29882186/cardiopulmonary-exercise-testing-for-surgical-risk-stratification-in-adults-with-congenital-heart-disease
#17
Trevor Birkey, Jennifer Dixon, Roni Jacobsen, Salil Ginde, Melodee Nugent, Ke Yan, Pippa Simpson, Joshua Kovach
Adult congenital heart disease (ACHD) patients often require repeat cardiothoracic surgery, which may result in significant morbidity and mortality. Currently, there are few pre-operative risk assessment tools available. In the general adult population, pre-operative cardiopulmonary exercise testing (CPET) has a predictive value for post-operative morbidity and mortality following major non-cardiac surgery. The utility of CPET for risk assessment in ACHD patients requiring cardiothoracic surgery has not been evaluated...
June 7, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29879852/predictors-of-extubation-failure-after-open-chest-cardiac-surgery-based-on-routinely-collected-data-the-importance-of-a-shared-interprofessional-clinical-assessment
#18
Gianfranco Sanson, Massimiliano Sartori, Lorella Dreas, Roberta Ciraolo, Adam Fabiani
BACKGROUND: Extubation failure (ExtF) is associated with prolonged hospital length of stay and mortality in adult cardiac surgery patients postoperatively. In this population, ExtF-related variables such as the arterial partial pressure of oxygen to fraction of inspired oxygen ratio (PaO2 /FiO2 ), rapid shallow breathing index, cough strength, endotracheal secretions and neurological function have been sparsely researched. AIM: To identify variables that are predictive of ExtF and related outcomes...
June 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29877218/is-systolic-right-ventricular-function-reduced-after-thoracic-non-cardiac-surgery-a-propensity-matched-echocardiographic-analysis
#19
Henning Johann Steffen, Sebastian Kalverkamp, Rashad Zayat, Rüdiger Autschbach, Jan-Wilhelm Spillner, Andreas Hagendorff, Nima Hatam
PURPOSE: To assess whether thoracic non-cardiac surgery has an influence on right ventricular function (RVF) compared to known impaired postoperative RV function after cardiac surgery. METHODS: In all, 50 patients (mean age: 61 years), who underwent thoracic non-cardiac surgery were included and matched using propensity score to 50 patients, receiving coronary artery bypass graft surgery (CABG) (CABGmatched ). All patients had transthoracic echocardiography (TTE) including two-dimensional speckle tracking (2D-STE) and tissue Doppler imaging (TDI) pre- and 1 week postoperatively...
June 7, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29872966/effect-of-preoperative-warming-on-intraoperative-hypothermia-a-randomized-controlled-trial
#20
Aaron Lau, Nasim Lowlaavar, Erin M Cooke, Nicholas West, Alexandra German, Dan J Morse, Matthias Görges, Richard N Merchant
PURPOSE: The purpose of this study was to evaluate the effects of preoperative forced-air warming on intraoperative hypothermia. METHODS: In this randomized-controlled trial, adult patients scheduled for elective, non-cardiac surgery under general anesthesia were stratified by scheduled surgical duration (< 2.5 hr or ≥ 2.5 hr) and then randomized to a pre-warming group using a BairPaws™ forced-air warming system for at least 30 min preoperatively or to a control group with warmed blankets on request...
June 5, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
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