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Osteochondrosis

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https://www.readbyqxmd.com/read/27917442/polymorphisms-in-ten-candidate-genes-are-associated-with-conformational-and-locomotive-traits-in-spanish-purebred-horses
#1
Natalia Sevane, Susana Dunner, Ana Boado, Javier Cañon
The Spanish Purebred horses, also known as Andalusian horses, compete to the highest standards in international dressage events. Gait and conformation could be used as early selection criteria to detect young horses with promising dressage ability. Although the genetic background of equine size variation has been recently uncovered, the genetic basis of horse conformational and locomotive traits is not known, hampered by the complex genetic architecture underlying quantitative traits and the lack of phenotypic data...
December 5, 2016: Journal of Applied Genetics
https://www.readbyqxmd.com/read/27898885/osteochondrosis-prevalence-and-severity-at-12-and-24-weeks-of-age-in-commercial-pigs-with-and-without-organic-complexed-trace-mineral-supplementation
#2
F Tóth, J L Torrison, L Harper, D Bussieres, M E Wilson, T D Crenshaw, C S Carlson
Maternal and progeny diets supplemented with 2 sources of trace mineral (TM) were evaluated for effects on the size and severity of osteochondrosis (OC) lesions in progeny produced by 64 Landrace × Large White sows. At breeding, sows were randomly assigned to maternal diets (gestation and lactation) consisting 1 of 2 TM treatments. One treatment consisted of inorganic TM (ITM) with ZnO, MnSO, and CuSO at concentrations to provide 150, 50, and 16.5 mg/kg diet of Zn, Mn, and Cu, respectively. The other treatment consisted of the same ITM concentrations plus an additional 50, 20, and 10 mg/kg diet of Zn, Mn, and Cu, respectively, supplied by a blend of AA-complexed TM (CTM) using Availa Sow...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27859501/the-development-of-locomotor-kinetics-in-the-foal-and-the-effect-of-osteochondrosis
#3
B M C Gorissen, C F Wolschrijn, F M Serra Bragança, A A J Geerts, W O J L Leenders, W Back, P R van Weeren
BACKGROUND: Foals stand and walk immediately after birth, but insight into the subsequent longitudinal development of their gait kinetics in the early juvenile phase and the possible influence of osteochondrosis thereon is lacking. OBJECTIVES: To quantify gait kinetics in foals during the first half year of life, taking into account their osteochondrosis status. STUDY DESIGN: Prospective, cohort study performed at a single stud farm. METHODS: Pressure plate measurements at walk and trot from eleven Dutch Warmblood foals during the first 24 weeks of life were used to determine body mass normalised peak vertical force, normalised vertical impulse and stance duration...
November 12, 2016: Equine Veterinary Journal
https://www.readbyqxmd.com/read/27821378/prevalence-of-humeral-head-osteochondrosis-in-the-greater-swiss-mountain-dog-and-the-border-collie-in-switzerland
#4
S Ohlerth, S Senn, U Geissbühler, P Kircher, M Flückiger
Osteochondrosis (OC) is common in large-breed dogs. According to the breeding guidelines of the Swiss kennel clubs, the shoulder joints are included in the radiographic screening for joint diseases in the Greater Swiss Mountain dog (GSMD) and the Border Collie (BC) since 1993 and 2003, respectively. The aim of this study was to estimate the overall prevalence of humeral head OC in these 2 breeds in Switzerland based on the data of the Swiss National Dysplasia Committees. All radiographs were re-evaluated to assess single radiographic changes...
November 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27734566/femoral-epiphyseal-cartilage-matrix-changes-at-predilection-sites-of-equine-osteochondrosis-quantitative-mri-second-harmonic-microscopy-and-histological-findings
#5
Gabrielle Martel, Charles-André Couture, Guillaume Gilbert, Stéphane Bancelin, Hélène Richard, Thomas Moser, Sabrina Kiss, François Légaré, Sheila Laverty
Osteochondrosis is an ischemic chondronecrosis of epiphyseal growth cartilage that results in focal failure of endochondral ossification and osteochondritis dissecans at specific sites in the epiphyses of humans and animals, including horses. The upstream events leading to the focal ischemia remain unknown. The epiphyseal growth cartilage matrix is composed of proteoglycan and collagen macromolecules and encases its vascular tree in canals. The matrix undergoes major dynamic changes in early life that could weaken it biomechanically and predispose it to focal trauma and vascular failure...
October 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27543146/preliminary-report-on-osteochondrosis-in-cattle-in-the-north-western-parts-of-south-africa
#6
Leon Prozesky, Johan Neser, Heinz Meissner, Kenneth Botha, Lubbe Jacobs, Craig Shepstone, Hannes Viljoen, Hinner Köster, Chris De Brouwer, Jan Van Zyl, Gerjan Van der Veen
The north-western part of South Africa, in particular, is well known for mineral imbalances. Aphosphorosis, resulting in rickets and osteomalacia, received a lot of attention at the turn of the nineteenth century (1882-1912). This was followed in 1997 by research on Vryburg hepatosis, another area-specific mineral imbalance-related disease in young calves reared on manganese-rich soil derived from the weathering of dolomitic (carbonate) rock formations. In 1982, a totally new syndrome (osteochondrosis) manifested in, amongst others, areas in South Africa where aphosphorosis was rife...
2016: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/27511310/pathogenesis-of-enterococcal-spondylitis-caused-by-enterococcus-cecorum-in-broiler-chickens
#7
L B Borst, M M Suyemoto, A H Sarsour, M C Harris, M P Martin, J D Strickland, E O Oviedo, H J Barnes
Enterococcal spondylitis (ES) is a disease of commercial broiler chickens, with a worldwide distribution. Symmetrical hind limb paralysis typical of ES results from infection of the free thoracic vertebra (FTV) by pathogenic strains of Enterococcus cecorum To determine the pathogenesis of ES, birds with natural and experimental ES were studied over time. In natural disease, case birds (n = 150) from an affected farm and control birds (n = 100) from an unaffected farm were evaluated at weeks 1-6. In control birds, intestinal colonization by E...
August 10, 2016: Veterinary Pathology
https://www.readbyqxmd.com/read/27491151/-the-application-of-antihomotoxic-drug-preparations-in-the-complex-treatment-in-patients-with-neurological-manifestations-of-lumbar-osteochondrosis
#8
A L Nadkevich, L S Babinets
The expediency of application homeosyniatry by preparations of Traumel S and Placenta Compositum after the offered chart in relation to a complex with classic acupuncture and in relation to the group of the generally accepted treatment has been proved in complex treatment patients with reflex syndromes of lumbar osteochondrosis. A similar conclusion was done after the statistically reliable (P < 0.05) dynamics of parameters of endogenous intoxication, liperoxydation and antioxydant systems of the protection (by the level of katalase, superoxyddismutase, SH-groups, ceruloplasmine)...
October 2015: Likars'ka Sprava
https://www.readbyqxmd.com/read/27471099/analysis-of-risk-factors-for-elbow-dysplasia-in-giant-breed-dogs
#9
Sarah Nemanic, Britton K Nixon, Wendy Baltzer
OBJECTIVE: Identify radiographic risk factors for development of elbow dysplasia in giant breed dogs less than one year of age. METHODS: Twenty-five giant breed puppies (Bernese Mountain dogs, English Mastiff, and Newfoundland) were studied. Both elbows of each dog were radiographed monthly from two to six months of age, then every other month until radial and ulnar physeal closure, followed two months later by bilateral elbow computed tomography. Radiographic parameters measured included the presence or absence of a separate centre of ossification of the anconeal process (SCOAP), medial coronoid disease (MCD), ununited anconeal process, humeral osteochondrosis, elbow incongruity, as well as the length of the radius and ulna, radius-to-ulna ratio, and date of closure of the radial and ulnar physes...
September 20, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27450859/arthroscopic-treatment-of-painful-sinding-larsen-johansson-syndrome-in-a-professional-handball-player
#10
C Kajetanek, M Thaunat, T Guimaraes, O Carnesecchi, M Daggett, B Sonnery-Cottet
Sinding-Larsen-Johansson (SLJ) syndrome is a type of osteochondrosis of the distal pole of the patella most often caused by repeated microtrauma. Here, we describe the case of a professional athlete with painful SLJ syndrome treated arthroscopically. A 29-year-old male professional handball player presented with anterior knee pain that persisted after 4 months of an eccentric rehabilitation protocol and platelet-rich plasma injections. Despite this conservative treatment, the patient could not participate in his sport...
September 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27448988/heritability-and-prevalence-of-selected-osteochondrosis-lesions-in-yearling-thoroughbred-horses
#11
J Russell, O Matika, T Russell, R J M Reardon
BACKGROUND: Osteochondrosis is considered multi-factorial in origin, with factors such as nutrition, conformation, body size, trauma and genetics thought to contribute to its pathogenesis. Few studies have investigated the effect of genetic variability of osteochondrosis in Thoroughbreds. OBJECTIVES: Describe the prevalence and genetic variability of a subset of osteochondrosis lesions in a group of Thoroughbred yearlings. STUDY DESIGN: Retrospective cohort study...
July 23, 2016: Equine Veterinary Journal
https://www.readbyqxmd.com/read/27430067/-the-age-and-work-experience-dynamics-of-indices-of-health-of-employees-criteria-for-comparison-of-occupational-and-nonoccupational-risks
#12
G A Sorokin
There are reported data of the analysis of parameters of the general morbidity (hypertension, chronic diseases, organs of respiratory and digestive system, adiposity, vertebral osteochondrosis) in dependence on age and work experience of dockers-mechanizators in seaport at various working conditions. Morbidity rate indices were calculated on results of the profound medical examination at annual periodic surveys of workers. There were analyzed ecological and ergonomic indices of working conditions, including an estimation of physiological intensity of the work...
2016: Gigiena i Sanitariia
https://www.readbyqxmd.com/read/27422688/candidate-gene-analysis-of-osteochondrosis-in-spanish-purebred-horses
#13
N Sevane, S Dunner, A Boado, J Cañon
Equine osteochondrosis (OC) is a frequent developmental orthopaedic disease with high economic impact on the equine industry and may lead to premature retirement of the animal as a result of chronic pain and lameness. The genetic background of OC includes different genes affecting several locations; however, these genetic associations have been tested in only one or few populations, lacking the validation in others. The aim of this study was to identify the genetic determinants of OC in the Spanish Purebred horse breed...
October 2016: Animal Genetics
https://www.readbyqxmd.com/read/27299057/late-stage-freiberg-infraction-in-a-division-i-collegiate-tennis-player
#14
Johnnie Faircloth, Jennifer J Mitchell, David S Edwards
INTRODUCTION: Freiberg infraction is a relatively rare osteochondrosis of the metatarsal head. The etiology of Freiberg infraction is poorly understood but likely involves factors such as, repetitive trauma and vascular compromise. When discovered early, Freiberg infraction can be cured with conservative measures but late presentations require surgical intervention. We present a case of stage V Freiberg infraction in a Division I collegiate tennis player that responded to conservative treatment...
July 2015: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/27283998/in-vivo-visualization-using-mri-t2-mapping-of-induced-osteochondrosis-and-osteochondritis-dissecans-lesions-in-goats-undergoing-controlled-exercise
#15
Ferenc Tóth, Frédéric H David, Elizabeth LaFond, Luning Wang, Jutta M Ellermann, Cathy S Carlson
In vivo visualization of subclinical osteochondrosis (OC) lesions, characterized by necrosis of epiphyseal growth cartilage, is necessary to clarify the pathogenesis of this disease. Hence, our objectives were to demonstrate induced necrosis of the epiphyseal cartilage in vivo using MRI and to monitor progression or resolution of resulting lesions. We also aimed to improve the goat model of OC by introducing controlled exercise. Vascular supply to the epiphyseal cartilage was surgically interrupted in four 5-day-old goats to induce ischemic cartilage necrosis in a medial femoral condyle...
June 10, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27149110/bsmi-apai-and-taqi-polymorphisms-in-the-vitamin-d-receptor-gene-vdr-and-association-with-lumbar-spine-pathologies-an-italian-case-control-study
#16
Alessandra Colombini, Marco Brayda-Bruno, Giovanni Lombardi, Samantha Jennifer Croiset, Cristina Ceriani, Cinzia Buligan, Mattia Barbina, Giuseppe Banfi, Sabina Cauci
Three adjacent single nucleotide polymorphisms of the vitamin D receptor gene (VDR) BsmI (rs1544410), ApaI (rs7975232), and TaqI (rs731236) are commonly studied in several pathologies. We aimed to evaluate the distribution of VDR BsmI, ApaI, and TaqI allele, genotype, and haplotype frequencies in an Italian cohort of 266 patients with lumbar spine disorders assessed by Magnetic Resonance Imaging and 252 asymptomatic controls. The exposure to putative risk factors was evaluated by a questionnaire. Polymorphisms were detected by PCR-RFLP and TaqMan® SNP Genotyping Assay...
2016: PloS One
https://www.readbyqxmd.com/read/27142101/osteochondrosis-dissecans-of-the-temporomandibular-joint-a-case-report-and-a-review-of-literature
#17
Wenko Smolka, Karl Sotlar, Max Weiss, Ullrich Müller-Lisse
A case of a 71-year-old female patient with osteochondrosis dissecans of the right temporomandibular joint is presented. Osteochondrosis dissecans usually occurs at the weight-bearing convex cartilage in all larger joints. It is rarely found in the temporomandibular joint and usually shows one or two loose bodies dislodged from defects which are present on the condylar head. Because of multiple loose bodies and a defect on the temporomandibular fossa, the case presented here is very uncommon.
September 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27094134/impact-of-feeding-and-housing-on-the-development-of-osteochondrosis-in-foals-a-longitudinal-study
#18
Luis Mendoza, Jean-Philippe Lejeune, Isabelle Caudron, Johann Detilleux, Charlotte Sandersen, Brigitte Deliège, Didier Serteyn
Osteochondrosis dissecans (OCD) is a developmental orthopedic disease caused by a failure of the endochondral ossification in epiphyseal plates and joint cartilage. This trouble may induce the presence of osteochondral fragments in the articulation, fissures or subchondral bone cysts in the growth cartilage. Occurrence of osteochondrosis is influenced by a complex interaction of different factors. Among these, the effect of the housing and the feeding of the foals during their first months of life, have been described as risk factors for the development of osteochondrosis...
May 1, 2016: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/27023824/radiologic-and-clinical-evaluation-12-months-after-anterior-cervical-diskectomy-and-dynamic-stabilization-of-the-segment-with-dynamic-cervical-implant
#19
Martin Dostal, Denis Laurent Kaech
Background Anterior cervical diskectomy (ACD) is an established therapy for degenerative cervical radiculopathy and myelopathy. Controversy remains regarding the dynamic or rigid stabilization of the segment. Methods We studied our first 31 patients treated with ACD plus the Dynamic Cervical Implant (DCI) as an alternative to fusion or to arthroplasty, treated between February 2009 and 2011. Radiologic data were collected before and 12 months after surgery. Clinical results were documented 12 months after surgery...
March 29, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27012925/a-longitudinal-study-on-the-performance-of-in-vivo-methods-to-determine-the-osteochondrotic-status-of-young-pigs
#20
Christian P Bertholle, Ellen Meijer, Willem Back, Arjan Stegeman, P René van Weeren, Arie van Nes
BACKGROUND: In today's porcine industry, lameness has a major welfare and economic impact, and is often caused by osteochondrosis (OC). The etiological factors of the disease have been studied in depth, however, to this day, little is known about the natural course of the disorder and how it can be detected at an early stage in pigs. The aim of this pilot study was to assess the potential of three non-invasive techniques for the detection and monitoring of early OC processes in piglets...
2016: BMC Veterinary Research
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