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https://www.readbyqxmd.com/read/28548996/distal-junctional-failure-following-pediatric-spinal-fusion
#1
Lorena V Floccari, Alvin W Su, Amy L McIntosh, Karl Rathjen, William J Shaughnessy, A Noelle Larson
BACKGROUND: Adjacent segment pathology is a known complication after spinal fusion, but little has been reported on junctional failure. A series of adolescent patients presented with acute distal junctional failure (DJF). We sought to determine any common features of these patients to develop a prevention strategy. METHODS: A retrospective review was conducted of pediatric patients who developed DJF after instrumented spinal fusion performed at 2 institutions from 1999 to 2013...
May 25, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28548698/novel-porcine-experimental-model-of-severe-progressive-thoracic-scoliosis-with-compensatory-curves-induced-by-interpedicular-bent-rigid-temporary-tethering
#2
Carlos Barrios, José Miguel Lloris, Juan Alonso, Borja Maruenda, Jesús Burgos, Rafael Llombart-Blanco, Luis Gil, Viviana Bisbal
Using flexible tethering techniques, porcine models of experimental scoliosis have shown scoliotic curves with vertebral wedging but very limited axial rotation. The aim of this experimental work was to induce a severe progressive scoliosis in a growing porcine model for research purposes. A unilateral spinal bent rigid tether was anchored to two ipsilateral pedicle screws in eight pigs. The spinal tether was removed after 8 weeks. Ten weeks later, the animals were sacrificed. Conventional radiographs and 3D CT-scans were taken to evaluate changes in the alignment of the thoracic spine...
May 26, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28545443/cervical-kyphosis-in-patients-with-lenke-type-1-adolescent-idiopathic-scoliosis-the-prediction-of-thoracic-inlet-angle
#3
Ce Zhu, Xi Yang, Bangjian Zhou, Lei Wang, Chunguang Zhou, Tingxian Ling, Limin Liu, Yueming Song
BACKGROUND: Several studies have explored cervical kyphosis (CK) in adolescent idiopathic scoliosis (AIS) patients. However, few studies have evaluated the cervical alignment in these patients according to their coronal curve type. The aim of this study was to analyze the radiological features of cervical sagittal alignment in Lenke 1 AIS patients before and after surgery. METHODS: This is a retrospective study enrolled 50 patients. Preoperative and postoperative standing full-length radiographs (at last follow-up after operation) were used to measure the coronal and sagittal parameters...
May 25, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28542100/global-spinal-alignment-in-patients-with-cervical-spondylotic-myelopathy
#4
Go Yoshida, Abdulmajeed Alzakri, Vincent Pointillart, Louis Boissiere, Ibrahim Obeid, Yukihiro Matsuyama, Jean Marc Vital, Olivier Gille
STUDY DESIGN: Prospective radiographic analysis of cervical spondylotic myelopathy (CSM) OBJECTIVE.: To clarify the pathophysiology of CSM, and use the characteristic of global spinal alignment for determining the surgical strategy. SUMMARY OF BACKGROUND DATA: Radiographic evaluation of CSM, in general, comprises cervical magnetic resonance imaging (MRI) and regional cervical radiography, which cannot distinguish between cervical hyperlodorsis with spinopelvic compensation and cervical lordorsis with normal global alignment...
May 24, 2017: Spine
https://www.readbyqxmd.com/read/28538597/surgical-management-of-thoracolumbar-kyphosis-in-patients-with-mucopolysaccharidosis-a-systematic-review
#5
Nicole Williams, Peter Cundy, Deborah Eastwood
STUDY DESIGN: Systematic Review OBJECTIVE.: To determine the indications and outcomes for surgical treatment of thoracolumbar kyphosis in patients with mucopolysaccharidoses (MPS) in order to define future studies. SUMMARY OF BACKGROUND DATA: Improvements in the medical treatment of MPS have increased lifespan and improved quality of life for many patients, but with no effect on thoracolumbar kyphosis. A greater number of these challenging patients may now be considered spinal surgical candidates...
May 22, 2017: Spine
https://www.readbyqxmd.com/read/28538444/changes-in-cervical-alignment-after-multilevel-schwab-grade-ii-thoracolumbar-osteotomies-for-adult-spinal-deformity
#6
George M Ghobrial, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
STUDY DESIGN: Retrospective Cohort OBJECTIVE.: To describe changes in cervical alignment(CA) and deformity (CD) after multilevel Schwab Grade II Osteotomies for adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: Reciprocal cervical and global changes after ASD surgery have not been previous described in the setting of multilevel osteotomy. METHODS: Patients with long-segment (> 5 levels) fusion and osteotomy for ASD were radiographically evaluated...
May 19, 2017: Spine
https://www.readbyqxmd.com/read/28529002/isyqol-a-rasch-consistent-questionnaire-for-measuring-health-related-quality-of-life-in-adolescents-with-spinal-deformities
#7
Antonio Caronni, Luciana Sciumè, Sabrina Donzelli, Fabio Zaina, Stefano Negrini
BACKGROUND CONTEXT: - Spinal deformities are commonly associated with poor HRQOL. Several questionnaires (e.g. SRS-24 and SRS-22) have been developed to evaluate HRQOL in these conditions. In adults as well as during growth, the HRQOL is considered one of the most relevant outcomes of both conservative and surgical treatment. Rasch analysis is a powerful statistical technique for developing high quality and valid questionnaires. The SRS-24 and SRS-22 have been evaluated using the Rasch analysis, but showed poor measurement properties...
May 18, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28527756/radiological-lumbar-stenosis-severity-predicts-worsening-sagittal-malalignment-on-full-body-standing-stereoradiographs
#8
Aaron J Buckland, Subaraman Ramchandran, Louis Day, Shay Bess, Themistocles Protopsaltis, Peter G Passias, Bassel G Diebo, Renaud Lafage, Virginie Lafage, Akhila Sure, Thomas J Errico
BACKGROUND CONTEXT: Patients with degenerative lumbar stenosis (DLS) adopt a forward flexed posture in an attempt to decompress neural elements. The relationship between sagittal alignment and severity of lumbar stenosis has not previously been studied. PURPOSE: We hypothesized that patients with increasing radiological severity of lumbar stenosis will exhibit worsening sagittal alignment. STUDY DESIGN: This is a cross-sectional study. PATIENT SAMPLE: Our sample consists of patients who have DLS...
May 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28526568/analysis-of-complications-following-posterior-vertebral-column-resection-for-the-treatment-of-severe-angular-kyphosis-greater-than-100%C3%A2
#9
Yunus Atici, Mehmet Bulent Balioglu, Deniz Kargin, Muhammed Mert, Akif Albayrak, Mehmet Akif Kaygusuz
OBJECTIVE: The aim of this study was to evaluate the complications, efficacy and safety of posterior vertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100°. METHODS: The medical records of 17 patients (mean age 17.9 (range, 9-27) years) with SAK who underwent PVCR, were reviewed. Mean follow-up period was 32.2 (range, 24-64) months. Diagnosis of the patients included congenital kyphosis in 11 patients, post-tuberculosis kyphosis in 3 patients and neurofibromatosis in 3 patients...
May 16, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28525478/a-radiographic-analysis-of-cervical-sagittal-alignment-in-adolescent-idiopathic-cervical-kyphosis
#10
Xiao-Long Shen, Ye Tian, Xu-Hui Zhou, Dong Ren, Peng Cao, Wen Yuan
OBJECTIVE: The aim of this study was to analyze the radiologic features of adolescent idiopathic cervical kyphosis. SUMMARY OF BACKGROUND DATA: There are few previous reports about radiographic analysis of cervical sagittal alignment of adolescent idiopathic cervical kyphosis. A new method was proposed in this article to evaluate the severity of cervical kyphosis. PATIENTS AND METHODS: A total of 41 adolescent patients with cervical kyphosis were reviewed...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28522402/prophylactic-vertebral-cement-augmentation-at-the-uppermost-instrumented-vertebra-and-rostral-adjacent-vertebra-for-the-prevention-of-proximal-junctional-kyphosis-and-failure-following-long-segment-fusion-for-adult-spinal-deformity
#11
George M Ghobrial, Daniel G Eichberg, John Paul G Kolcun, Karthik Madhavan, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are common problems after long segment (>5 levels) thoracolumbar instrumented fusions in the treatment of adult spinal deformity (ASD). No specific surgical strategy has definitively been shown to lower the risk of PJK as the result of a multifactorial etiology. PURPOSE: To assess the incidence of PJK and PJF in patients treated with prophylactic polymethylmethacrylate(PMMA) cement augmentation at the uppermost instrumented vertebrae(UIV) and rostral adjacent vertebrae(UIV+1)...
May 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28521184/one-stage-posterior-grade-4-osteotomy-and-bone-graft-fusion-at-pseudarthrosis-for-the-treatment-of-kyphotic-deformity-with-andersson-lesions-in-ankylosing-spondylitis
#12
Tingxian Ling, Bangjian Zhou, Ce Zhu, Xi Yang, Yueming Song, Zhe Qiang, Limin Liu
OBJECTIVES: The optimal surgical procedure for treating kyphotic deformity with Andersson lesions (ALs) in ankylosing spondylitis (AS) patients is controversial. The one-stage posterior osteotomy and bone graft fusion approach is rarely reported. The aim of the present study was to report a new surgical procedure involving one-stage posterior grade 4 osteotomy and bone graft fusion for the treatment of kyphotic deformity with ALs in AS. PATIENTS AND METHODS: Eleven patients with ALs in AS were enrolled...
May 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28509688/a-prevalence-study-of-thoracic-scoliosis-in-chilean-patients-aged-10-20-years-using-chest-radiographs-as-a-screening-tool
#13
Julio Urrutia, Pablo Besa, Francisco Bengoa
To determine the prevalence of thoracic scoliosis in patients 10-20 years old using radiographs as a screening tool, we studied 783 patients who obtained chest radiographs for nonspinal reasons. We measured thoracic curvature in coronal and sagittal planes; we determined whether age, sex, and sagittal curvature predicted the coronal curvature. The prevalence of scoliosis was 9.3%: 7.0% had curvatures 10°-20°; 1.0% had curvatures 20°-30°; and 1.3% had curvatures of at least 30°. Females (13%) presented larger prevalence of scoliosis than males (4...
May 15, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28506822/the-effect-of-prophylactic-vertebroplasty-on-the-incidence-of-proximal-junctional-kyphosis-and-proximal-junctional-failure-following-posterior-spinal-fusion-in-adult-spinal-deformity-a-5-year-follow-up-study
#14
Tina Raman, Emily Miller, Christopher T Martin, Khaled Kebaish
BACKGROUND CONTEXT: The incidence of proximal junctional kyphosis (PJK) ranges from 5-46% following adult spinal deformity (ASD) surgery. Approximately 66-76% of PJK occurs within 3 months of surgery. A subset of these patients, reportedly 26-47%, develop proximal junctional failure (PJF) within 6 months postoperatively. To date, there are no studies evaluating the impact of prophylactic vertebroplasty on PJK/PJF incidence at long term follow-up. PURPOSE: The purpose of this study is to evaluate the long term radiographic and clinical outcomes, and incidence of PJK and PJF, after prophylactic vertebroplasty for long segment thoracolumbar posterior spinal fusion...
May 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28504622/-severe-cervical-kyphosis-causing-sudden-inspiratory-stridor
#15
Karen Lise Dahl Andersen, Allan Bach, Rikke Haahr Iversen, Søren Helbo Skaarup
An 85-year-old woman was brought to an accident and emergency department with breathing difficulties accompanied by inspiratory stridor. She was being treated for hypertension and severe osteoporosis which had caused thoracal and cervical fractures of the columna. Intubation was initiated as she desaturated and deteriorated despite maximum oxygen therapy. The intubation revealed a subglottic stenosis as a consequence of a recent osteoporotic fracture in the cervical columna. This represents a rare cause of respiratory failure as all other cardial, pulmonary and allergic aetiologies had been eliminated...
May 8, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28503540/comparisons-of-incidence-of-spinal-and-lower-extremity-deformities-according-to-the-physical-characteristics-between-sports-major-and-nonmajor-college-students
#16
Jangwon Lee
This research was performed to identify the incidence of spinal and lower extremity deformity and to identify the relationship of the incidence between the physical characteristics. One hundred forty-seven Physical Education major students and 54 nonmajor students participated in this study. Data collecting was performed by questionnaire and visual postural evaluation. The incidences of genu varus (P<0.00001), genu recurvatum (P=0.0007), forward head (P<0.00001), lordosis (P<0.00001), and scoliosis (P=0...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28503323/severe-cervical-flexion-myelopathy-with-long-tract-signs-a-case-report-and-a-review-of-literature
#17
Takahito Fujimori, Akiko Tamura, Toshitada Miwa, Motoki Iwasaki, Takenori Oda
INTRODUCTION: Hirayama disease, a type of cervical flexion myelopathy, is a rare neurological disease characterized by muscular atrophy of the forearms and hands. Generally, the pathology is limited to the gray matter of the anterior horns in the lower cervical spinal cord. However, in rare cases the damage can spread to the white matter and present as long tract signs. CASE PRESENTATION: We report on a 30-year-old female whose onset presented as unilateral muscle atrophy of the right hand in her teens...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28484794/femoral-head-retroposition-as-a-potential-compensatory-mechanism-in-patients-with-a-severe-mismatch-between-pelvic-incidence-and-lumbar-lordosis
#18
Xiaofei Cheng, Kai Zhang, Xiaojiang Sun, Changqing Zhao, Hua Li, Jie Zhao
OBJECTIVE: Severe mismatch between pelvic incidence (PI) and lumbar lordosis (LL) leads to extra anterior displacement of the gravity line. The objective of this study is to investigate whether femoral head retroposition is a separate compensatory mechanism responsible for the extra anterior displacement. SUBJECTS AND METHODS: Based on the values of PI and LL, 94 patients were divided into the PI-LL match group (PI-LL ≤ 0°), the mild PI-LL mismatch group (20°> PI-LL >0°), and the severe PI-LL mismatch group (PI-LL ≥ 20°)...
May 9, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28482200/analysis-of-compensatory-mechanisms-in-the-pelvis-and-lower-extremities-in-patients-with-pelvic-incidence-and-lumbar-lordosis-mismatch
#19
Xiaofei Cheng, Kai Zhang, Xiaojiang Sun, Changqing Zhao, Hua Li, Jie Zhao
The objective was to analyze the compensatory effect of the pelvis and lower extremities on sagittal spinal malalignment in patients with pelvic incidence (PI) and lumbar lordosis (LL) mismatch. A series of parameters including PI, LL, PI-LL, thoracic kyphosis (TK), pelvic tilt (PT), sacral slope (SS), knee flexion angle (KFA), tibial obliquity angle (TOA), femoral obliquity angle (FOA), femur pelvis angle (FPA) and pelvic shift (PS) were measured. Patients with PI-LL mismatch were divided into pelvic retroversion group and pelvic retroposition group based on their PT and PS, and then the parameters were compared within the two groups and with the control group...
May 1, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28476546/infantile-gangliosidoses-mapping-a-timeline-of-clinical-changes
#20
Jeanine R Jarnes Utz, Sarah Kim, Kelly King, Richard Ziegler, Lynn Schema, Evelyn S Redtree, Chester B Whitley
BACKGROUND: Infantile gangliosidoses include GM1 gangliosidosis and GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease). To date, natural history studies in infantile GM2 (iGM2) have been retrospective and conducted through surveys. Compared to iGM2, there is even less natural history information available on infantile GM1 disease (iGM1). There are no approved treatments for infantile gangliosidoses. Substrate reduction therapy using miglustat has been tried, but is limited by gastrointestinal side effects...
April 29, 2017: Molecular Genetics and Metabolism
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