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Yasutsugu Yukawa, Fumihiko Kato, Kota Suda, Masatsune Yamagata, Takayoshi Ueta, Munehito Yoshida
PURPOSE: This study aims to establish normative data for parameters of spino-pelvic and spinal sagittal alignment, gender related differences and age-related changes in asymptomatic subjects. METHODS: A total of 626 asymptomatic volunteers from Japanese population were enrolled in this study, including 50 subjects at least for each gender and each decade from 3rd to 8th. Full length, free-standing spine radiographs were obtained. Cervical lordosis (CL; C3-7), thoracic kyphosis (TK; T1-12), lumbar lordosis (LL; T12-S1), pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS) and sagittal vertical axis (SVA) were measured...
October 22, 2016: European Spine Journal
Erika Roddy, Mohammad Diab
BACKGROUND CONTEXT: Short-term readmission rates are becoming widely utilized as a quality and performance metrics for hospitals. Data on unplanned short-term readmission after spine fusion for deformity in pædiatric patients is limited. PURPOSE: To characterize the rate and risk factors for short-term readmission after spine fusion for deformity in pædiatric patients. STUDY DESIGN: Retrospective cohort study PATIENT SAMPLE: State In-Patient Databases from NY, UT, NE, FL, NC (years 2006-2010) and CA (years 2006-2011)...
October 17, 2016: Spine Journal: Official Journal of the North American Spine Society
Anand Pandey, Vipin Gupta, Shailendra P Singh, Vijendra Kumar, Rajesh Verma
A trophic ulcer is a pressure ulcer caused by external trauma to a part of the body that is compromised due to disease, vascular insufficiency, or loss of afferent nerve fibers. Spinal dysraphism (ie, neural tube defects [NTD]) such as meningomyelocele is a risk factor for developing these ulcers in adults and pediatric patients. Information regarding the occurrence of trophic ulcers in pediatric patients with NTD is lacking. A review of the English-language literature on skin/neuropathic ulcers in patients with NTDs, irrespective of study design, published between 1975 and 2014, was undertaken using the PubMed database...
December 2015: Ostomy/wound Management
Pooria Hosseini, Jeff B Pawelek, Stacie Nguyen, George H Thompson, Suken A Shah, John M Flynn, John P Dormans, Behrooz A Akbarnia, Growing Spine Study Group
PURPOSE: Is there any relationship between lengthening intervals and rod fracture in traditional growing rod (TGR) surgery? METHODS: A multicenter EOS database was queried for patients who had: (1) dual growing rods for EOS; (2) minimum 2-year follow-up; (3) a minimum of 2 lengthenings; and (4) revision surgery due to rod fracture. Of 138 patients who met the criteria: 56 patients experienced at least one-rod fracture (RF group) and 82 patients had no rod fractures (NRF group)...
October 19, 2016: European Spine Journal
J Tayierjiang, N Waresijiang, H Wang
Objective: To evaluate the clinical results of the patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar had been treated by one stage posterior surgical procedure to debriment of lesion and titian mesh bone fusion with internal fixation by pedicle screw system. Method: From May 2008 to March 2014, there were total 30 patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar in Department of Orthopaedics, the People's Hospital of Xinjiang Uygur Autonoumy Region...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Louis M Day, Subaraman Ramchandran, Cyrus M Jalai, Bassel G Diebo, Barthelemy Liabaud, Renaud Lafage, Themistocles Protopsaltis, Peter G Passias, Frank J Schwab, Shay Bess, Thomas J Errico, Virginie Lafage, Aaron J Buckland
STUDY DESIGN: Retrospective clinical and radiographic single-center study OBJECTIVE.: Assess simultaneous cervical spine and lower extremity compensatory changes with changes in thoracolumbar spinal alignment. SUMMARY OF BACKGROUND DATA: Full-body stereoradiographic imaging allows better understanding of reciprocal changes in cervical and lower extremity alignment in the setting of thoracolumbar malalignment. Few studies describe the simultaneous effect of alignment correction on these mechanisms...
October 17, 2016: Spine
Junlin Yang, Zifang Huang, Michael Grevitt, Jun Li, Fobao Li, Jingfan Yang
STUDY DESIGN: To report a new technique. OBJECTIVE: To introduce a new method of precise correction controlling for ankylosing spondylitis kyphosis. SUMMARY OF BACKGROUND DATA: The exact angle method is excellent for calculating the pedicle subtraction osteotomy angle but is difficult to perform during surgery. In this study, the precise rod bending technique was proposed as a new method for precise correction controlling for ankylosing spondylitis kyphosis through illustrative cases...
November 2016: Clinical Spine Surgery
Qinliang Li, Cai Yun, Shichun Li
BACKGROUND: Complications in posterior pedicle screw fixation using a conventional posterior approach for thoracolumbar fractures include vertebral height loss, kyphosis relapse and breakage, or loosening of instrumentation. The purpose of this study was to evaluate the clinical effects of transpedicular bone grafting and pedicle screw fixation in injured vertebrae using a paraspinal approach for thoracolumbar fractures. METHODS: We retrospectively analyzed 50 patients with thoracolumbar fractures treated with transpedicular bone grafting and pedicle screw fixation in injured vertebrae using a paraspinal approach...
October 17, 2016: Journal of Orthopaedic Surgery and Research
Xiaoyu Wang, Laure Boyer, Franck Le Naveaux, Richard M Schwend, Carl-Eric Aubin
BACKGROUND: Differential rod contouring is used to achieve 3-dimensional correction in adolescent idiopathic scoliosis instrumentations. How vertebral rotation correction is correlated with the amount of differential rod contouring is still unknown; too aggressive differential rod contouring may increase the risk of bone-screw connection failure. The objective was to assess the 3-dimensional correction and bone-screw forces using various configurations of differential rod contouring. METHODS: Computerized patient-specific biomechanical models of 10 AIS cases were used to simulate AIS instrumentations using various configurations of differential rod contouring...
October 6, 2016: Clinical Biomechanics
Olivier Boucherat, Kim Landry-Truchon, Rifdat Aoidi, Nicolas Houde, Valérie Nadeau, Jean Charron, Lucie Jeannotte
BACKGROUND: Reciprocal epithelial-mesenchymal communications are critical throughout lung development, dictating branching morphogenesis and cell specification. Numerous signaling molecules are involved in these interactions but how epithelial-mesenchymal crosstalk is coordinated remains unclear. The ERK/MAPK pathway transduces several important signals in lung formation. Epithelial inactivation of both Mek genes, encoding ERK/MAPK kinases, causes lung agenesis and death. Conversely, Mek mutation in mesenchyme results in lung hypoplasia, trachea cartilage malformations, kyphosis, omphalocele and death...
October 17, 2016: Developmental Dynamics: An Official Publication of the American Association of Anatomists
Frank-Martin Haecker, Sergio Sesia
BACKGROUND: For specific therapy to correct pectus excavatum (PE), conservative treatment with the vacuum bell (VB) was introduced more than 10 years ago in addition to surgical repair. Preliminary results using the VB were encouraging. We report on our 13-year experience with the VB treatment including the intraoperative use during the Nuss procedure and present some technical innovations. METHODS: A VB with a patient-activated hand pump is used to create a vacuum at the anterior chest wall...
September 2016: Annals of Cardiothoracic Surgery
Ang Deng, Hong-Qi Zhang, Ming-Xing Tang, Shao-Hua Liu, Yu-Xiang Wang, Qi-Le Gao
OBJECTIVE The objective of this study was to evaluate the clinical efficacy of posterior-only surgical correction of dystrophic scoliosis in patients with neurofibromatosis Type 1 (NF1) using a multiple anchor point method (MAPM). METHODS From 2005 to 2014, 31 patients (mean age 13.5 years old, range 10-22 years old) suffering from dystrophic scoliosis associated with NF1 underwent posterior-only surgical correction using a MAPM. The apex of the deformity was thoracic (n = 25), thoracolumbar (n = 4), and lumbar (n = 2)...
October 14, 2016: Journal of Neurosurgery. Pediatrics
Martin H Pham, Alexander Tuchman, Lance Smith, Andre M Jakoi, Neil N Patel, Vivek A Mehta, Frank L Acosta
Proximal junctional kyphosis is an increasingly recognized complication following long-segment posterior spinal fusion for adult spinal deformity. The authors describe a novel technique for interspinous ligament reinforcement at the proximal adjacent levels using a cadaveric semitendinosus tendon graft secured with an Ethibond No. 2 double filament (Ethicon, Somerville, New Jersey) via the Krackow suture weave. A retrospective review identified 4 patients who had received this graft. No proximal junctional kyphosis was seen at a mean short-term follow-up of 5...
October 13, 2016: Orthopedics
Wenhao Hu, Bin Wang, Hongyu Run, Xuesong Zhang, Yan Wang
BACKGROUND: It is estimated that upwards of 50,000 individuals suffer traumatic fracture of the spine each year, and the instability of the fractured vertebra and/or the local deformity results in pain and, if kyphosis increases, neurological impairment can occur. There is a significant controversy over the ideal management. The purpose of the study is to present clinical and radiographic results of pedicle subtraction osteotomy and disc resection with cage placement in correcting post-traumatic thoracolumbar kyphosis...
October 12, 2016: Journal of Orthopaedic Surgery and Research
Marc Dreimann, Michael Hoffmann, Lennart Viezens, Lukas Weiser, Patrick Czorlich, Sven Oliver Eicker
PURPOSE: Metastatic epidural spinal cord compression (MESCC) often requires anterior-posterior decompression and stabilization. To reduce approach-related complications, single-stage posterolateral vertebrectomy and 360° fusion is often performed. However, a sufficient reduction of kyphotic deformity through this approach has not been reported. The purpose of this study is to investigate the efficacy of kyphotic deformity reduction by this approach in MESCC. METHODS: A retrospective analysis and chart review was performed for 14 consecutive patients who underwent a vertebrectomy and decompression from a posterolateral approach...
October 11, 2016: European Spine Journal
A Shea, L De Risio, H Carruthers, A Ekiri, E Beltran
To describe the development of clinical signs (CS) and outcome of L-2-hydroxyglutaric aciduria (L-2-HGA), owners of 119 Staffordshire bull terriers positive for the known L-2-hydroxyglutarate dehydrogenase autosomal-recessive mutations were requested to complete a questionnaire regarding their pet's CS. Questionnaires were returned for 27 dogs, all with neurological abnormalities-not all questions were answered in all cases. The mean age of CS onset was 12 months (range 2.5-60). Gait dysfunction was reported in 26/26 dogs, with stiffness of all four limbs the most common (24/26) and earliest recognised abnormality...
October 11, 2016: Veterinary Record
Marin Stančić, Ivana Stančić, Petra Barl, Ivan Pašalić
OBJECTIVE: Scarcity of implants during the economic crisis has partially replaced cervical spondylotic myelopathy decompression and instrumented fusion with implant-less expansile cervical laminopalsty. The aim of the study was comparison of the results obtained with instrumented anterior cervical corpectomy and fusion (ACCF) with implant-less expansile cervical laminoplasty (ECL). METHODS: Patients suffering from cervical spondylotic myelopathy (CSM) Nurick 3-5, with preoperative tethering and postoperative untethering were included...
October 7, 2016: World Neurosurgery
Wendy B Katzman, Neeta Parimi, Ziba Mansoori, Lorenzo Nardo, Deborah M Kado, Peggy M Cawthon, Lynn M Marshall, John T Schousboe, Nancy E Lane
OBJECTIVE: Investigate cross-sectional and longitudinal associations of Diffuse Idiopathic Skeletal Hyperostosis (DISH) and thoracic kyphosis in older persons. METHODS: DISH and kyphosis were assessed in 1500 men from the Osteoporosis in Men (MrOS) study and 1267 women from the Study of Osteoporotic Fractures (SOF). DISH was assessed in baseline lateral spine radiographs, and Cobb angle of kyphosis was measured from baseline and follow-up radiographs, mean 4.6 years later in men, and 3...
October 9, 2016: Arthritis Care & Research
Leanda McKenna, Xavier Cornwall, Sian Williams
BACKGROUND: Scapular orientation may be influenced by static body posture (sitting and standing) and contribute to the development of shoulder pain. Therefore, a consistent body posture should be considered when assessing scapular orientation as well as enhancing optimal scapular positioning. OBJECTIVE: To determine whether there are differences in scapular orientation between standing, neutral sitting, and habitual sitting, while adjusting for spinal posture. DESIGN: A single group randomized repeated measures study...
October 6, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Bomma Yashwanth, Rajesh Pamanji, J Venkateswara Rao
This study outlines the toxic effects of Quinalphos (QP), an organophosphrous insecticide on the development of zebrafish (Danio rerio) embryos, with special emphasis on toxicomorphomics and toxicokinetics of target enzyme, AChE. A range of concentrations was used to elucidate the median lethal concentration (LC50) of Quinalphos. Furthermore, embryos were exposed to two sub-lethal concentrations LC10 (0.66mg/L) and LC20 (1.12mg/L) along with a median lethal concentration (3.0mg/L) for 96h. Several morphological aberrations like lordosis, kyphosis, scoliosis, heart edema, breaks in the neuronal tube and underdeveloped facial parts were noticed, which were of concentration and time dependent...
October 1, 2016: Aquatic Toxicology
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