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Fear of recurrence

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https://www.readbyqxmd.com/read/28081031/intracranial-hemorrhage-recurrence-on-vitamin-k-antagonist-severity-of-the-first-episode-and-hasbled-score-fail-to-identify-high-risk-patients-from-the-chirone-study
#1
Daniela Poli, Emilia Antonucci, Francesco Dentali, Sophie Testa, Gualtiero Palareti
The most feared complication of vitamin K antagonists (VKAs) treatment is intracranial hemorrhage (ICH). The previously published CHIRONE Study fails to identify risk factors associated with ICH recurrence after VKAs resumption. The aim of this secondary analysis of the study is to evaluate if patients who need surgery or with severe neurological sequelae after the first episode show a higher risk of ICH recurrence. The HASBLED score was used to stratify bleeding risk and to evaluate the distribution of recurrence in relation to each class of risk...
January 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28078223/testosterone-therapy-and-prostate-cancer
#2
REVIEW
Alexander W Pastuszak, Katherine M Rodriguez, Taylor M Nguyen, Mohit Khera
The use of exogenous testosterone to treat hypogonadism in the men with a history of prostate cancer (CaP) remains controversial due to fears of cancer recurrence or progression. Due to the detrimental impact of hypogonadism on patient quality of life, recent work has examined the safety of testosterone therapy (TTh) in men with a history of CaP. In this review, we evaluate the literature with regards to the safety of TTh in men with a history of CaP. TTh results in improvements in quality of life with little evidence of biochemical recurrence or progression in men with a history of CaP, or de novo cancer in unaffected men...
December 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28068158/follow-up-after-rectal-cancer-developing-and-testing-a-novel-patient-led-follow-up-program-study-protocol
#3
Ida Hovdenak Jakobsen, Therese Juul, Inge Bernstein, Peter Christensen, Frank Svendsen Jensen, Christoffer Johansen, Susie Lindhardt Larsen, Søren Laurberg, Mogens Rørbæk Madsen, Ole Thorlacius-Ussing, Henriette Vind Thaysen
BACKGROUND: The main treatment for non-metastatic rectal cancer (RC) is surgical resection. Late adverse effects that are highly prevalent and negatively impact patients' symptom burden and quality of life are: bowel-, urological and sexual dysfunctions; psychological distress; fear of recurrence. Patients and clinicians have requested a more patient-centred follow-up, balancing the focus on detection of recurrence, and physiological and psychological late adverse effects. The current follow-up program primarily focuses on detection of recurrence, with less attention on late adverse effects...
January 9, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28055119/a-pilot-randomized-controlled-trial-of-cognitive-bias-modification-to-reduce-fear-of-breast-cancer-recurrence
#4
Wendy G Lichtenthal, Geoffrey W Corner, Elizabeth T Slivjak, Kailey E Roberts, Yuelin Li, William Breitbart, Stephanie Lacey, Malwina Tuman, Katherine N DuHamel, Victoria S Blinder, Courtney Beard
BACKGROUND: The most common, persistent concern among survivors of breast cancer is the fear that their disease will return, yet to the authors' knowledge, few interventions targeting fear of cancer recurrence (FCR) have been developed to date. The current pilot study examined the feasibility, acceptability, and preliminary efficacy of a home-delivered cognitive bias modification intervention to reduce FCR. The intervention, called Attention and Interpretation Modification for Fear of Breast Cancer Recurrence (AIM-FBCR), targeted 2 types of cognitive biases (ie, attention and interpretation biases)...
January 5, 2017: Cancer
https://www.readbyqxmd.com/read/28052692/measuring-illness-representations-in-breast-cancer-survivors-bcs-prescribed-tamoxifen-modification-and-validation-of-the-revised-illness-perceptions-questionnaire-ipq-bcs
#5
Zoe Moon, Rona Moss-Morris, Myra S Hunter, Lyndsay D Hughes
OBJECTIVE: The Revised Illness Perceptions Questionnaire (IPQ-R), widely used to assess illness perceptions, may fail to measure unique characteristics of different illnesses. This study modified and validated the IPQ-R for breast cancer survivors to provide detailed understanding of the specific illness perceptions held by these patients. DESIGN: Initial modifications were made following qualitative interviews and were revised in a think-aloud study. The modified scale was tested in 753 breast cancer survivors prescribed tamoxifen...
January 4, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28052599/fear-of-new-or-recurrent-melanoma-after-treatment-for-localised-melanoma
#6
Katy J L Bell, Yachna Mehta, Robin M Turner, Rachael L Morton, Mbathio Dieng, Robyn Saw, Pascale Guitera, Kirsten McCaffery, Donald Low, Cynthia Low, Marisa Jenkins, Les Irwig, Angela C Webster
OBJECTIVE: To estimate the amount of fear of new or recurrent melanoma among people treated for localised melanoma in an Australian specialist centre. METHODS: We randomly selected 400 potential participants from all those treated for localised melanoma at the Melanoma Institute Australia during 2014 (n = 902). They were asked to complete an adapted version of the Fear of Cancer Recurrence Inventory (FCRI). We calculated summary statistics for demographics, clinical variables and total FCRI and subscale scores...
January 4, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28031675/spontaneous-resolution-of-catheter-induced-iatrogenic-vein-graft-dissection-first-case-report-and-review-of-literature
#7
Prakash Suryanarayana, Shubha Kollampare, Mohammad Reza Movahed
An 86-year-old female patient with a history of bypass surgery was admitted for recurrent dyspnea and chest pain on exertion. She underwent coronary angiography showing high-grade saphenous vein graft stenosis supplying the right coronary. During an attempt to perform percutaneous intervention, saphenous vein graft to the right coronary artery was injured by the guide catheter resulting in dissection with thrombus formation but with normal distal blood flow. The procedure was abandoned since she had normal distal flow and also due to a fear of causing extension of the dissection with further manipulation...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/27998215/psychoeducational-intervention-to-reduce-fear-of-cancer-recurrence-in-people-at-high-risk-of-developing-another-primary-melanoma-results-of-a-randomized-controlled-trial
#8
Mbathio Dieng, Phyllis N Butow, Daniel S J Costa, Rachael L Morton, Scott W Menzies, Shab Mireskandari, Stephanie Tesson, Graham J Mann, Anne E Cust, Nadine A Kasparian
Purpose People with a history of melanoma commonly report a fear of cancer recurrence (FCR), yet psychologic support is not routinely offered as part of ongoing melanoma care. This randomized controlled trial examined the efficacy of a psychoeducational intervention to reduce FCR and improve psychologic adjustment in this patient group compared with usual care. Methods The intervention comprised a newly developed psychoeducational resource and three telephone-based psychotherapeutic sessions over a 1-month period timed in accordance with dermatologic appointments...
December 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27992680/exploring-characteristics-predictors-and-consequences-of-fear-of-cancer-recurrence-among-asian-american-breast-cancer-survivors
#9
Kimlin Tam Ashing, Dalnim Cho, Lily Lai, Sophia Yeung, Lucy Young, Christina Yeon, Yuman Fong
OBJECTIVE: To address the fear of cancer recurrence (FCR) research gap, we used prospective data to explore FCR predictors and FCR associations with health-related quality of life (HRQOL) among Asian American breast cancer survivors (BCS). METHODS: A total of 208 diverse Asian American BCS completed T1 survey and 137 completed T2 survey after 1-year. RESULTS: FCR scores (range = 0-4) were 2.01 at T1 and 1.99 at T2 reflecting low-to-moderate FCR...
December 19, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27987454/patient-reported-outcomes-in-ductal-carcinoma-in-situ-a-systematic-review
#10
REVIEW
Madeleine T King, Zoë E Winters, Ivo A Olivotto, Andrew J Spillane, Boon H Chua, Christobel Saunders, A Helen Westenberg, G Bruce Mann, Petrina Burnett, Phyllis Butow, Claudia Rutherford
Ductal carcinoma in situ (DCIS) is a pre-invasive breast cancer with excellent prognosis but with potential adverse impacts of diagnosis and treatment on quality of life and other patient-reported outcomes (PROs). We undertook a systematic review to synthesise current evidence about PROs following diagnosis and treatment for DCIS. We searched five electronic databases (from database inception to November 2015), cross-referenced and contacted experts to identify studies that reported PROs after DCIS treatment...
January 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/27974160/capturing-and-manipulating-activated-neuronal-ensembles-with-cane-delineates-a-hypothalamic-social-fear-circuit
#11
Katsuyasu Sakurai, Shengli Zhao, Jun Takatoh, Erica Rodriguez, Jinghao Lu, Andrew D Leavitt, Min Fu, Bao-Xia Han, Fan Wang
We developed a technology (capturing activated neuronal ensembles [CANE]) to label, manipulate, and transsynaptically trace neural circuits that are transiently activated in behavioral contexts with high efficiency and temporal precision. CANE consists of a knockin mouse and engineered viruses designed to specifically infect activated neurons. Using CANE, we selectively labeled neurons that were activated by either fearful or aggressive social encounters in a hypothalamic subnucleus previously known as a locus for aggression, and discovered that social-fear and aggression neurons are intermixed but largely distinct...
November 23, 2016: Neuron
https://www.readbyqxmd.com/read/27969078/sex-differentials-in-the-risk-factors-of-post-traumatic-stress-disorder-among-tsunami-survivors-in-tamil-nadu-india
#12
Pyari T T, Sundari Ravindran T K
This study assessed if pre disaster, with-in disaster and post disaster factors predicted Post Traumatic Stress Disorder (PTSD) differently, among men and women survivors of the 2004 Southeast Asian tsunami in Kanyakumari district, Tamil Nadu, India. PTSD was identified using a validated tool, Impact of Events Scale-Revised (IES-R) among the participants in a cross-sectional community based survey (n=485). Case control analysis of 299 subjects was done to determine the predictors of PTSD. The odds of having PTSD were 6...
October 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27966025/fear-of-recurrence-or-progression-as-a-link-between-somatic-symptoms-and-perceived-stress-among-cancer-survivors
#13
Daniel L Hall, Inga T Lennes, William F Pirl, Emily R Friedman, Elyse R Park
PURPOSE: Many cancer survivors report experiencing somatic symptoms as well as elevated stress. Theoretical models have suggested that physical symptoms generate subjective stress via fears of recurrence or progression. To date, this indirect effect has not been established empirically. This study aimed to provide preliminary evidence as to whether fear of recurrence or progression is an intermediary between somatic symptom severity and perceived stress among heterogeneous cancer survivors...
December 13, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27965391/reducing-future-fears-by-suppressing-the-brain-mechanisms-underlying-episodic-simulation
#14
Roland G Benoit, Daniel J Davies, Michael C Anderson
Imagining future events conveys adaptive benefits, yet recurrent simulations of feared situations may help to maintain anxiety. In two studies, we tested the hypothesis that people can attenuate future fears by suppressing anticipatory simulations of dreaded events. Participants repeatedly imagined upsetting episodes that they feared might happen to them and suppressed imaginings of other such events. Suppressing imagination engaged the right dorsolateral prefrontal cortex, which modulated activation in the hippocampus and in the ventromedial prefrontal cortex (vmPFC)...
December 27, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27924358/fear-of-cancer-recurrence-and-physical-well-being-among-chinese-cancer-survivors-the-role-of-conscientiousness-positive-reappraisal-and-hopelessness
#15
Kelly Yu-Hsin Liao, Nelson C Y Yeung, Celia C Y Wong, Krystal Warmoth, Qian Lu
PURPOSE: The degree to which conscientiousness contributes to well-being in Chinese cancer survivors and the mechanisms through which conscientiousness is associated with well-being remain unclear. Based on Lent's restorative well-being model [1], the current study tested a mediation model of the contribution of conscientiousness, positive reappraisal, and hopelessness to fear of cancer recurrence (FCR), and physical well-being in a sample of 238 Chinese cancer survivors. METHOD: Participants completed self-report questionnaires...
December 6, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27922923/fear-of-recurrence-as-a-predictor-of-care-needs-for-long-term-breast-cancer-survivors
#16
Su-Ying Fang, Susan Jane Fetzer, Kuo-Ting Lee, Yao-Lung Kuo
BACKGROUND: The improved survival rate for breast cancer has increased the number of women living with the diagnosis for more than 5 years. Limited studies have focused on the care needs for long-term healthy survivors of breast cancer. OBJECTIVE: The aims of this study were to understand the care needs of long-term breast cancer survivors and identify related factors that influence these needs. METHODS: A convenience sampling with a correlational study design was used...
December 5, 2016: Cancer Nursing
https://www.readbyqxmd.com/read/27920643/elevated-lipase-during-initial-presentation-of-ulcerative-colitis-in-a-pediatric-patient-do-we-check-for-it
#17
Piyali Ray, Melissa R Van Arsdall
There are very few reports of elevated lipase in pediatric inflammatory bowel disease (IBD). Symptoms of pancreatitis may be masked by abdominal pain in pediatric IBD. During the initial presentation of IBD in our patient, lipase was elevated to more than 3 times the upper limit of normal. Normalization of values coincided with remission of IBD. This may be due to extraintestinal involvement of the pancreas as part of the inflammatory process or due to leakage of pancreatic enzymes from an inflamed gut or mediated by inflammatory cytokines...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27900169/neuromuscular-exercise-and-back-counselling-for-female-nursing-personnel-with-recurrent-non-specific-low-back-pain-study-protocol-of-a-randomised-controlled-trial-nurse-rct
#18
Jaana H Suni, Marjo Rinne, Markku Kankaanpää, Annika Taulaniemi, Sirpa Lusa, Harri Lindholm, Jari Parkkari
INTRODUCTION: Nursing personnel have high risk for incidence of low back pain (LBP) followed by development of chronic pain and disability. Multiple risk factors such as patient handling, night shift work and lack of supporting work culture have been identified. In subacute LBP, high-fear avoidance is prognostic for more pain, disability and not returning to work. Lack of leisure-time physical activity predicts long-term sickness absence. The purpose of this study is to compare effectiveness of 6-month neuromuscular exercise and counselling in treating back pain in female nursing personnel with recurrent non-specific LBP pain compared with either (exercise or counselling) alone and a non-treatment control group...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27898259/use-of-hormone-therapy-for-menopausal-symptoms-and-quality-of-life-in-breast-cancer-survivors-safe-and-ethical
#19
María Fernanda Garrido Oyarzún, Camil Castelo-Branco
Breast cancer is the most prevalent cancer in women and presently, the breast cancer survivors are an important group of women that faced the several consequences of estrogen deficiency, which is especially common in women after chemotherapy. The most bothersome is the vasomotor symptoms, which are effectively relieved by hormonal therapy (HT). Also, the increased risk of osteoporosis and coronary artery disease is major problem to be resolved in pos of maintaining a good quality of life. Fearing cancer recurrence, most physicians do not offer HT to women with a history of breast cancer...
November 29, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27887806/a-comparison-of-two-psychological-interventions-for-newly-diagnosed-gynecological-cancer-patients
#20
Sharon L Manne, Shannon Myers Virtue, Melissa Ozga, Deborah Kashy, Carolyn Heckman, David Kissane, Norman Rosenblum, Mark Morgan, Lorna Rodriquez
OBJECTIVE: This study compared the efficacy of two psychological interventions, a coping and communication-enhancing intervention (CCI) and supportive counseling (SC), in reducing depressive symptoms, cancer-specific distress, fear of recurrence, and emotional well-being of women diagnosed with gynecological cancer. Demographic, medical, and psychological moderators of intervention effects were evaluated. METHODS: Three hundred fifty-two women with gynecological cancer were randomly assigned to eight sessions of CCI, eight sessions of SC, or usual care (UC)...
February 2017: Gynecologic Oncology
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