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Fear of recurrence

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https://www.readbyqxmd.com/read/29351056/remediation-of-radiation-induced-cognitive-dysfunction-through-oral-administration-of-the-neuroprotective-compound-nsi-189
#1
Barrett Allen, Munjal M Acharya, Celine Lu, Erich Giedzinski, Nicole Chmielewski, David Quach, Mike Hefferan, Karl K Johe, Charles L Limoli
Clinical management of primary and secondary central nervous system (CNS) malignancies frequently includes radiotherapy to forestall tumor growth and recurrence after surgical resection. While cranial radiotherapy remains beneficial, adult and pediatric brain tumor survivors suffer from a wide range of debilitating and progressive cognitive deficits. Although this has been recognized as a significant problem for decades, there remains no clinical recourse for the unintended neurocognitive sequelae associated with these types of cancer treatments...
January 19, 2018: Radiation Research
https://www.readbyqxmd.com/read/29343143/colorectal-cancer-patients-preferences-for-type-of-caregiver-during-survivorship-care
#2
T Wieldraaijer, L A M Duineveld, S C Donkervoort, W B Busschers, H C P M van Weert, J Wind
PURPOSE: Colorectal cancer (CRC) survivors are currently included in a secondary care-led survivorship care programme. Efforts are underway to transfer this survivorship care to primary care, but met with some reluctance by patients and caregivers. This study assesses (1) what caregiver patients prefer to contact for symptoms during survivorship care, (2) what patient factors are associated with a preferred caregiver, and (3) whether the type of symptom is associated with a preferred caregiver...
January 17, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/29330232/interventions-must-be-realistic-to-be-useful-and-completed-in-family-medicine
#3
EDITORIAL
Marjorie A Bowman, Dean A Seehusen, Anne Victoria Neale
Being realistic while helping our patients is this issue's theme. Given the volume of tasks required in family medicine, recommendations for improvements in direct care or care measurement cannot just be evidence-based but must also be realistic. On the list of realistic: ordering antipsychotics for symptoms of dementia in the elderly, despite recommendations to not do so; ordering antidepressants without fear that the patient could develop hypertension; mental health care providers in primary care offices; forced choice for opioid management; plus agenda setting for visit efficiency...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29313090/the-effect-of-pelvic-pain-and-urinary-incontinence-on-women-s-self-rated-health-in-northern-mexico
#4
Hilda García-Pérez, Sioban D Harlow, Catalina Denman
INTRODUCTION AND HYPOTHESIS: This study was designed to assess the effect of gynecological morbidities on Mexican women's self-rated health status and emotional health. METHODS: A cross-sectional population-based study was conducted among Mexican women aged 25-54. We analyzed information on 1,303 participants living in Hermosillo, Mexico. Multiple logistic regression was used to assess the effect of having any one of three kinds of pelvic pain, urinary incontinence or both of these conditions on women's self-rated health...
January 8, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29261524/core-set-of-patient-reported-outcomes-in-pancreatic-cancer-coprac-an-international-delphi-study-among-patients-and-health-care-providers
#5
Lennart B van Rijssen, Arja Gerritsen, Inge Henselmans, Mirjam A Sprangers, Marc Jacobs, Claudio Bassi, Olivier R Busch, Carlos Fernández-Del Castillo, Zhi Ven Fong, Jin He, Jin-Young Jang, Ammar A Javed, Sun-Whe Kim, Laura Maggino, Abhishek Mitra, Vikas Ostwal, Silvia Pellegrini, Shailesh V Shrikhande, Johanna W Wilmink, Christopher L Wolfgang, Hanneke W van Laarhoven, Marc G Besselink
OBJECTIVE: To establish an international core set of patient-reported outcomes (PROs) selected by both patients and healthcare providers (HCPs) from the United States (US), Europe, and Asia. SUMMARY BACKGROUND DATA: PROs are increasingly recognized in pancreatic cancer studies. There is no consensus on which of the many available PROs are most important. METHODS: A multicenter Delphi study among patients with pancreatic cancer (curative- and palliative-setting) and HCPs in 6 pancreatic centers in the US (Baltimore, Boston), Europe (Amsterdam, Verona), and Asia (Mumbai, Seoul) was performed...
December 19, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29251693/the-fear-of-cancer-recurrence-literature-continues-to-move-forward-a-review-article
#6
Christine Maheu, Jacqueline Galica
PURPOSE OF REVIEW: The volume of literature addressing fear of cancer recurrence (FCR) is rapidly increasing. A summary of key developments in the research and treatment of FCR was published by Sharpe et al. in 2017, and the current review focuses on works published thereafter. RECENT FINDINGS: A comprehensive literature review was conducted to provide an up-to-date summary of peer-reviewed publications focusing on FCR. The search consisted of the most recent FCR reports published between 2016 and 2017, which can be broadly categorized as: methods of assessment; associations with FCR; FCR and caregivers; and FCR interventions...
December 14, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29243170/associations-among-physical-symptoms-fear-of-cancer-recurrence-and-emotional-well-being-among-chinese-american-breast-cancer-survivors-a-path-model
#7
Dalnim Cho, Qiao Chu, Qian Lu
PURPOSE: Most existing studies on fear of cancer recurrence (FCR) are exploratory without theoretical underpinnings and have been conducted among non-Hispanic Whites. Based on theoretical models, we hypothesized that more physical symptoms (pain and fatigue) would be associated with higher FCR, which, in turn would be related to lower emotional well-being among Chinese American breast cancer survivors. METHODS: Participants were 77 Chinese American women who were diagnosed with breast cancer of stages 0-III...
December 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29238619/hippocampal-regulation-of-postsynaptic-density-homer1-by-associative-learning
#8
Nicholas E Clifton, Darren Cameron, Simon Trent, Lucy H Sykes, Kerrie L Thomas, Jeremy Hall
Genes involved in synaptic plasticity, particularly genes encoding postsynaptic density proteins, have been recurrently linked to psychiatric disorders including schizophrenia and autism. Postsynaptic density Homer1 proteins contribute to synaptic plasticity through the competing actions of short and long isoforms. The activity-induced expression of short Homer1 isoforms, Homer1a and Ania-3, is thought to be related to processes of learning and memory. However, the precise regulation of Homer1a and Ania-3 with different components of learning has not been investigated...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/29220878/a-qualitative-study-of-the-experience-of-lower-extremity-wounds-and-amputations-among-people-with-diabetes-in-philadelphia
#9
Frances K Barg, Peter F Cronholm, Ebony E Easley, Trocon Davis, Michelle Hampton, D Scot Malay, Cornelius Donohue, Jinsup Song, Stephen R Thom, David J Margolis
The purpose of this study was to explore perceptions among people with type 2 diabetes about foot ulcers and lower extremity amputations. This was a qualitative observational study utilizing open-ended, semistructured interviews of 39 people with diabetes who were purposively selected because they had either a foot ulcer (n = 19) or a lower extremity amputation (n = 20). Interviews were audio-recorded, deidentified, and entered into NVivo 10.0 for coding and analysis. Our integrated analytic approach combined inductively and deductively derived codes that were applied to all transcripts...
December 8, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29204708/a-systematic-literature-review-of-the-prevalence-of-and-risk-factors-for-supportive-care-needs-among-women-with-gynaecological-cancer-and-their-caregivers
#10
REVIEW
Vanessa L Beesley, Chalachew Alemayehu, Penelope M Webb
PURPOSE: This review aimed to determine the prevalence of met and unmet needs, and the risk factors for unmet needs among people affected by gynaecological cancer. METHODS: The review was undertaken using the PRISMA guidelines. Eligible studies were identified though a range of electronic databases in October and November 2016. Study quality was independently appraised by two people. RESULTS: Thirty-seven studies were included (1 review, 24 quantitative and 12 qualitative)...
December 4, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29203977/radical-treatment-of-rectal-cancer-in-elderly-is-feasible-than-feared-results-from-a-tertiary-care-centre
#11
Madhu Muralee, Rajesh Singh, Arun Peter Mathew, Kurian Cherian, K Chandramohan, Paul Augustine, S Roshni, Iqbal Ahamed
The thought of subjecting an elderly patient with rectal cancer to protocol-based neoadjuvant chemoradiation (NACTRT), surgery and adjuvant chemotherapy is sought with fear due to their multiple comorbidities and impaired functional status associated with the process of ageing. Hence, many a times the treatment is compromised and it is a fact that this subgroup of patients is underrepresented in most of the clinical trials. This study was aimed at analysing the perioperative and oncologic outcomes after protocol-based treatment of rectal cancer in the elderly patients, defined here as those with age ≥70 years...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29188268/sensitivity-of-preference-based-quality-of-life-measures-for-economic-evaluations-in-early-stage-melanoma
#12
Mbathio Dieng, Nadine A Kasparian, Anne E Cust, Daniel S J Costa, Anh Tran, Phyllis N Butow, Scott W Menzies, Graham J Mann, Rachael L Morton
Importance: The diagnosis of a life-threatening disease like melanoma can affect all aspects of a person's life, including health-related quality of life (HRQOL) and psychological aspects of melanoma such as fear of cancer recurrence (FCR). Economic evaluations of psychological interventions require preference-based (utility) instruments that are sensitive to changes in well-being and HRQOL; however, very few studies have evaluated the sensitivity of these instruments when used for people with melanoma...
November 29, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29180853/new-insights-into-frequency-and-contents-of-fear-of-cancer-progression-recurrence-fop-fcr-in-outpatients-with-colorectal-carcinoma-crc-receiving-oral-capecitabine-a-pilot-study-at-a-comprehensive-cancer-center
#13
Jochen Hefner, Sara Berberich, Elena Lanvers, Maria Sanning, Ann-Kathrin Steimer, Volker Kunzmann
Background: Fear of cancer progression/recurrence (FOP/FCR) is considered one of the most prevalent sources of distress in cancer survivors and associated with lower quality of life and functional impairment. Detailed measures of FOP/FCR are needed because little is known about the knowledge of FOP/FCR, its associations with the patient-doctor relationship, and the rate of adequate therapy. Colorectal cancer (CRC) is one of the most prevalent cancer entities, and oral capecitabine is widely prescribed as treatment...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29176331/management-of-work-through-the-seasons-of-cancer-survivorship
#14
Saskia F A Duijts
PURPOSE OF REVIEW: Survival from cancer has expanded enormously over the past decades. It is estimated that 40-50% of all cancer survivors are of working age at time of diagnosis and thus potentially part of the labor force. The seasons of survivorship can be used as a steppingstone to describe issues regarding employability survivors are dealing with. RECENT FINDINGS: The acute survival stage begins at the point of diagnosis. Disclosure of diagnosis, and flexibility of both employers and (occupational) healthcare professionals are important factors in this stage...
November 25, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29171109/a-systematic-review-of-quantitative-observational-studies-investigating-psychological-distress-in-testicular-cancer-survivors
#15
REVIEW
Allan 'Ben' Smith, Claudia Rutherford, Phyllis Butow, Ian Olver, Tim Luckett, Peter Grimison, Guy Toner, Martin Stockler, Madeleine King
OBJECTIVE: Testicular cancer (TC) affects young men and may cause psychological distress despite a good prognosis. This systematic review evaluated the prevalence, severity and correlates of anxiety, depression, fear of cancer recurrence (FCR) and distress in TC survivors. METHODS: A systematic search of literature published 1977-2017 was conducted to find quantitative studies including TC survivor-reported outcomes relevant to review objectives. The quality of included articles was assessed, and a narrative synthesis conducted...
November 23, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29168035/prevalence-and-correlates-of-high-fear-of-cancer-recurrence-in-late-adolescents-and-young-adults-consulting-a-specialist-adolescent-and-young-adult-aya-cancer-service
#16
Belinda Thewes, Suzanne E J Kaal, Jose A E Custers, Eveliene Manten-Horst, Rosemarie Jansen, Petra Servaes, Winette T A van der Graaf, Judith B Prins, Olga Husson
OBJECTIVE: High fear of cancer recurrence (FCR) is a frequently reported problem among cancer patients. Previous research has shown that younger age is associated with higher levels of FCR. However, little attention has been given to date about how FCR manifests itself among adolescent and young adult (AYA) cancer patients. This study explores the prevalence, correlates of high FCR, and its association with HRQoL in cancer patients in their late adolescence or young adulthood. METHODS: Seventy-three AYA cancer patients, aged 18-35 years at diagnosis, consulted the AYA team of the Radboud University Medical Center completed questionnaires including the Cancer Worry Scale (CWS), Quality of Life-Cancer Survivors (QOL-CS), and Hospital Anxiety and Depression Scale (HADS)...
November 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29167084/parent-s-experiences-of-their-children-suffering-febrile-seizures
#17
Emma Westin, Märta Sund Levander
PURPOSE: To explore parents' experiences of their child suffering febrile seizures. DESIGN AND METHOD: Seven mothers and four fathers with experience of one or several febrile seizures in their children were interviewed. A qualitative content analysis with an inductive approach was performed. RESULT: Five themes emerged; emotional experiences, in terms of anxiety and fear, and need for control, need for support, need for acknowledgement and need for comfort...
November 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29166308/an-evaluation-of-the-choice-for-contralateral-prophylactic-mastectomy-and-patient-concerns-about-recurrence-in-a-reconstructed-cohort
#18
Ian C Sando, Jessica I Billig, Shoshana W Ambani, Casey T Kraft, Kelley M Kidwell, Lin Zhong, Kevin C Chung, Adeyiza O Momoh
BACKGROUND: Rising contralateral prophylactic mastectomy rates are a subject of national concern. This study assessed (1) factors critical to patients when deciding on contralateral prophylactic mastectomy and (2) patients' quality of life related to concerns about recurrence after unilateral or bilateral breast reconstruction. METHODS: Patients with stage 0 to III breast cancer who underwent unilateral mastectomy or contralateral prophylactic mastectomy and breast reconstruction at a single institution between 2000 and 2012 were identified...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29149897/enablers-and-barriers-to-secondary-prophylaxis-for-rheumatic-fever-among-m%C3%A4-ori-aged-14-21-in-new-zealand-a-framework-method-study
#19
Hilary Barker, John G Oetzel, Nina Scott, Michelle Morley, Polly E Atatoa Carr, Keri Bolton Oetzel
BACKGROUND: Acute rheumatic fever (ARF) rates have declined to near zero in nearly all developed countries. However, in New Zealand rates have not declined since the 1980s. Further, ARF diagnoses in New Zealand are inequitably distributed--occurring almost exclusively in Māori (the indigenous population) and Pacific children--with very low rates in the majority New Zealand European population. With ARF diagnosis, secondary prophylaxis is key to prevent recurrence. The purpose of this study was to identify the perceived enablers and barriers to secondary recurrence prophylaxis following ARF for Māori patients aged 14-21...
November 17, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29142834/two-stage-thyroidectomy-in-the-era-of-intraoperative-neuromonitoring
#20
Christos Christoforides, Ioannis Papandrikos, Georgios Polyzois, Nikolaos Roukounakis, Gianlorenzo Dionigi, Kyriakos Vamvakidis
Background: The use of intraoperative neuromonitoring (IONM) provides surgeons with real time information about recurrent laryngeal nerves (RLN) functional integrity. Hence, allowing them to modify the initially scheduled bilateral procedure, to a two-stage thyroidectomy in cases of loss of signal (LOS) on the first side of resection resulting in minimization of bilateral RLN injury. The purpose of our study was to present our results since the implementation of the above mentioned process in both malignant and benign thyroid disease...
October 2017: Gland Surgery
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