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Intermittent claudication

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https://www.readbyqxmd.com/read/28087891/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#1
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
January 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28087551/cost-effectiveness-of-superficial-femoral-artery-endovascular-interventions-in-the-uk-and-germany-a-modelling-study
#2
Benjamin C Kearns, Steven M Thomas
OBJECTIVES: To assess the lifetime costs and cost-effectiveness of 5 endovascular interventions to treat superficial femoral arterial disease. DESIGN: A model-based health economic evaluation. An existing decision analytical model was used, with updated effectiveness data taken from the literature, and updated costs based on purchasing prices. SETTING: UK and German healthcare perspectives were considered. PARTICIPANTS: Patients with intermittent claudication of the femoropopliteal arteries eligible for endovascular treatment...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28065441/clinimetric-evaluation-of-the-vascular-quality-of-life-questionnaire-in-patients-with-lower-limb-ischaemia
#3
A P Conijn, T B K Santema, S Bipat, M J W Koelemay, R J de Haan
OBJECTIVES: Although commonly used to measure health related quality of life in patients with lower limb ischaemia, the measurement properties of the VascuQol and its assumed underlying health dimensions have not been studied in depth. The objective of this study was therefore to evaluate aspects of reliability and validity of the Dutch version of the VascuQol in patients with intermittent claudication (IC) and critical limb ischaemia (CLI). METHODS: Two datasets containing 195 patients with IC and 150 patients with CLI were used...
January 4, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28018500/the-effect-of-hachimi-jio-gan-ba-wei-di-huang-wan-on-the-quality-of-life-in-patients-with-peripheral-arterial-disease-a-prospective-study-using-kampo-medicine
#4
Koji Kawago, Shunya Shindo, Hidenori Inoue, Junetsu Akasaka, Shinya Motohashi, Go Urabe, Masahiro Sato, Hirotomo Uchiyama, Hitoshi Ogino
Objective: To assess whether Hachimi-jio-gan (HJG), a preparation of Kampo medicine (traditional Japanese medicine), improves quality of life (QOL) in patients with peripheral arterial disease (PAD). Materials and Methods: Among the patients with PAD being followed in the Department of Cardiovascular Surgery at Tokyo Medical University Hachioji Medical Center, those with intermittent claudication (IC) and in stable condition regarding PAD severity were registered. We registered the patients from April 2014 to March 2015...
2016: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/27998046/supervised-exercise-therapy-it-does-work-but-how-to-set-up-a-program
#5
David Hageman, Marijn M VAN DEN Houten, Steffie Spruijt, Lindy N Gommans, Marc R Scheltinga, Joep A Teijink
Intermittent claudication (IC) is a manifestation of peripheral arterial disease. IC has a high prevalence in the older population, is closely associated with other expressions of atherosclerotic disease and often co-exists in multimorbid patients. Treatment of IC should address reduction of cardiovascular risk and improvement of functional capacity and health-related quality of life (QoL). As recommended by contemporary international guidelines, the first-line treatment includes supervised exercise therapy (SET)...
December 19, 2016: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27990191/relief-of-lower-back-and-leg-pain-after-myelography
#6
Rui Guo, Toshihiko Sakakibara, Tetsutaro Mizuno, Koji Akeda, Tetsushi Kondo, Yuichi Kasai
INTRODUCTION: It is well-known that many patients will have adverse reactions such as headache and nausea after undergoing myelography, but we have often seen cases where symptoms such as lower back pain and leg pain were alleviated following myelography. To the best of our knowledge, such clinical cases of post-myelographic alleviation have not been reported. MATERIALS AND METHODS: A total of 325 patients with a degenerative lumbar spinal disorder who underwent myelography were prospectively investigated at four hospitals from April 2012 to March 2014 to survey the post-myelographic alleviation of lower back and leg pain prospectively...
2016: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/27979038/baseline-assessment-and-comparison-of-arterial-anatomy-hyperemic-flow-and-skeletal-muscle-perfusion-in-peripheral-artery-disease-the-cardiovascular-cell-therapy-research-network-patients-with-intermittent-claudication-injected-with-aldh-bright-cells-cctrn-pace
#7
Bharath Ambale Venkatesh, Victor Nauffal, Chikara Noda, Tomoki Fujii, Phillip C Yang, Judy Bettencourt, Erin P Ricketts, Michael Murphy, Nicholas J Leeper, Lem Moyé, Ray F Ebert, Raja Muthupillai, David A Bluemke, Emerson C Perin, Alan T Hirsch, João A C Lima
BACKGROUND: Peripheral artery disease (PAD) is important to public health as a major contributor to cardiovascular morbidity and mortality. Recent developments in magnetic resonance imaging (MRI) techniques permit improved assessment of PAD anatomy and physiology, and may serve as surrogate end points after proangiogenic therapies. METHODS: The PACE study is a randomized, double-blind, placebo-controlled clinical trial designed to assess the physiologic impact and potential clinical efficacy of autologous bone marrow-derived ALDH(br) stem cells...
January 2017: American Heart Journal
https://www.readbyqxmd.com/read/27974252/radiation-dosage-for-percutaneous-pad-treatment-is-different-in-cardiovascular-disciplines-results-from-an-eleven-year-population-based-registry-in-the-metropolitan-area-of-hamburg
#8
C-A Behrendt, H C Rieß, F Heidemann, H Diener, F Rohlffs, R Hohnhold, E S Debus
OBJECTIVE: The worldwide prevalence of peripheral artery disease (PAD) has evolved to an intervention as the primary treatment option and therefore radiation is used with escalating incidence. Dose area product (DAP) correlates well with the total energy imparted to the patient during fluoroscopic interventions. This study aims to determine whether there are any associations among stage of disease, gender, age, and expertise on the radiation dose in single endovascular treatments of PAD...
December 11, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27970174/tct-788-safety-and-efficacy-of-endovascular-therapy-for-octogenarians-with-peripheral-artery-disease-presenting-intermittent-claudication-due-to-aortoiliac-lesions
#9
Shota Okuno, Osamu Iida, Yoshimitsu Soga, Daizo Kawasaki, Yasutaka Yamauchi, Kenji Suzuki, Keisuke Hirano, Ryoji Koshida, Daisuke Kamoi, Junichi Tazaki, Michiaki Higashitani, Yoshiaki Shintani, Terutoshi Yamaoka, Shinya Okazaki, Nobuhiro Suematsu, Taketsugu Tsuchiya, Yusuke Miyashita, Norihiko Shinozaki, Antonella De Santis, Masaaki Uematsu
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27960614/long-term-individual-shear-rate-therapy-counterpulsation-enhances-plasma-nitrite-release-in-patients-with-pad
#10
Michèle Brix, Eva-Elina Buschmann, Andreas Zietzer, Jonnel Anthony Jaurigue, Lulu Li, Constantin Jungk, Ivo Buschmann, Doreen Janke, Philipp Hillmeister
BACKGROUND: Individual shear rate therapy (ISRT) has been designed as a novel non-invasive treatment option for peripheral artery disease (PAD) patients and has been shown to improve endothelial function and walking distance. The aim of this study was to elucidate the impact of ISRT on the level of nitric oxide in patient blood plasma and the expression of related molecular markers in peripheral blood mononuclear cells (PBMCs). Molecular diagnostic tests were performed for two ISRT trials...
December 14, 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27942099/study-of-pentoxifylline-effects-on-motility-and-viability-of-spermatozoa-from-infertile-asthenozoospermic-males
#11
Aliye Ghasemzadeh, Farid Karkon-Shayan, Solmaz Yousefzadeh, Mohammad Naghavi-Behzad, Kobra Hamdi
BACKGROUND: The quality of semen is one of the major parameters in male infertility. Pentoxifylline, a methylxanthine derivative, is an agent primarily used in the treatment of intermittent claudication and other vascular disorders. Studies have shown that pentoxifylline enhances the quality and quantity of sperms. In this study, we have investigated the in vitro effects of pentoxifylline on viability and motility of spermatozoa in samples of infertile oligoasthenozoospermic males. MATERIALS AND METHODS: In this observer-blinded clinical trial, semen samples of 25 infertile oligoasthenozoospermic males were collected in Alzahra Educational Medical Center of Tabriz University of Medical Sciences from August 2010 to August 2012...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27939742/long-term-primary-patency-rate-after-nitinol-self-expandable-stents-implantation-in-long-totally-occluded-femoropopliteal-tasc-ii-c-d-lesions-retrospective-study
#12
Mahmoud Farouk Elmahdy, Piergiovanni Buonamici, Maurizio Trapani, Renato Valenti, Angela Migliorini, Guido Parodi, David Antoniucci
BACKGROUND: Endovascular therapy for long femoropopliteal lesions using percutaneous transluminal balloon angioplasty or first-generation of peripheral stents has been associated with unacceptable one-year restenosis rates. However, with recent advances in equipment and techniques, a better primary patency rate is expected. So, this study was conducted to detect the long-term primary patency rate of nitinol self-expandable stents implanted in long, totally occluded femoropopliteal lesions (TASC II type C & D), and determine the predictors of reocclusion or restenosis in the stented segments...
November 18, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27932554/inflammatory-cytokine-levels-after-endovascular-therapy-in-patients-with-peripheral-artery-disease
#13
Yasushi Ueki, Takashi Miura, Yusuke Miyashita, Souichiro Ebisawa, Hirohiko Motoki, Atsushi Izawa, Jun Koyama, Uichi Ikeda
We evaluated the impact of endovascular therapy (EVT) on inflammatory cytokine levels and its relationship with in-stent restenosis in patients with peripheral artery disease. The study prospectively enrolled 35 patients with intermittent claudication who underwent EVT of the iliofemoral artery. Levels of interleukin 6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and tumor necrosis factor α (TNF-α) were measured using enzyme-linked immunosorbent assay before and at 2 hours, 4 hours, and 3 months after EVT...
December 8, 2016: Angiology
https://www.readbyqxmd.com/read/27932292/graduated-compression-stockings-does-not-decrease-walking-capacity-and-muscle-oxygen-saturation-during-six-minute-walk-test-in-intermittent-claudication-patients
#14
Bruno Remígio Cavalcante, Raphael Mendes Ritti-Dias, Antônio Henrique Germano Soares, Wagner Jorge Ribeiro Domingues, Glauco Fernandes Saes, Flávio Henrique Duarte, Aline de Paula da Cruz, Nelson Wolosker, Pedro Puech-Leão, Gabriel Grizzo Cucato, Antonio Eduardo Zerati
BACKGROUND: We analyze the effects of graduated compression stoking (GCS) on walking capacity and oxygen saturation in intermittent claudication (IC) patients. METHODS: Eighteen patients with IC performed the six-minute walking test in two conditions in random order: GCS or placebo sock. Onset claudication distance and total walking distance were obtained. The calf muscle oxygen saturation was continuously monitored before, during and after six-minute walk test...
December 5, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27908805/understanding-patient-acceptance-of-risk-with-treatment-options-for-intermittent-claudication
#15
Abigail H M Morbi, Sophie Coles, Mostafa Albayati, Ian M Nordon, Cliff Shearman
BACKGROUND: Intermittent claudication has a major impact on the quality of life and functional ability of the patient. However, when treating these patients, management is largely influenced by vascular surgeons' perceptions of risk. There is little information available regarding the level of risk that patients perceive to be acceptable, when considering complications of treatment. This study investigates patients' acceptance of risk associated with current management options for intermittent claudication and explores factors associated with greater risk acceptance...
November 28, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27903955/effect-of-diabetes-mellitus-on-walking-distance-parameters-after-supervised-exercise-therapy-for-intermittent-claudication-a-systematic-review
#16
David Hageman, Lindy Nm Gommans, Marc Rm Scheltinga, Joep Aw Teijink
Some believe that certain patients with intermittent claudication (IC) may be unsuitable for supervised exercise therapy (SET), based on the presence of comorbidities and the possibly increased risks. We conducted a systematic review (MEDLINE, EMBASE and CENTRAL) to summarize evidence on the potential influence of diabetes mellitus (DM) on the response to SET. Randomized and nonrandomized studies that investigated the effect of DM on walking distance after SET in patients with IC were included. Considered outcome measures were maximal, pain-free and functional walking distance (MWD, PFWD and FWD)...
November 30, 2016: Vascular Medicine
https://www.readbyqxmd.com/read/27890849/hybrid-treatment-of-a-suprarenal-aortic-aneurysm-with-an-infrarenal-aortobifemoral-surgical-graft-and-a-fenestrated-stent-graft
#17
Sebastian Nagel, Athanasios Katsargyris, Kyriakos Oikonomou, Eric L G Verhoeven
BACKGROUND: The aim of this study was to report a hybrid technique for the treatment of a suprarenal aortic aneurysm (SAA) in a patient with iliac occlusive disease. Initially, an infrarenal aortobifemoral surgical graft was implanted, followed by deployment of a fenestrated bifurcated stent graft at the suprarenal part of the aorta. METHODS: A 69-year-old man presented with a 51-mm saccular suprarenal aortic aneurysm and iliac occlusive disease with intermittent claudication...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27872352/additional-functional-outcomes-after-endovascular-treatment-for-intermittent-claudication
#18
Anne Sofie F Larsen, Morten B Jacobsen, Jarlis Wesche, Nils Einar Kløw
BACKGROUND: Endovascular treatment (EVT) for intermittent claudication (IC) is performed in selected patients where conservative treatment and training fail. Treatment outcomes reported in vascular registries (survival, limb-survival, and re-intervention rate) are inadequate for low-risk patients with IC. Additional measurements of blood flow reduction and functional impairment clarify the indication for treatment and facilitate outcome evaluation. PURPOSE: To analyze the additional outcome information on peripheral arterial pressures and walking capacity obtained from a local registry of EVT...
November 21, 2016: Acta Radiologica
https://www.readbyqxmd.com/read/27866700/angiopoietin-related-growth-factor-is-independently-associated-with-lower-extremity-peripheral-arterial-disease
#19
Hao Nie, Yue Liang, Hong-Xia Wang, Hua-Liang Ren, Yue-Wei Wang, Fang-Da Li, Yue-Hong Zheng
AIMS: The present study investigated the association of serum levels of angiopoietin-related growth factor (AGF) with lower extremity peripheral arterial disease (LEPAD). METHODS: The study group is comprised of 105 patients with lower extremity peripheral arterial disease. The control group consisted of 80 individuals without lower extremity peripheral arterial disease. Serum AGF concentrations were determined by enzyme-linked immunosorbent assay. The relationship between AGF and clinical and biochemical parameters was studied...
October 27, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27833919/the-impact-of-walking-exercises-and-resistance-training-upon-the-walking-distance-in-patients-with-chronic-lower-limb-ischaemia
#20
Maria Szymczak, Grzegorz Oszkinis, Marian Majchrzycki
Objective. The objective of this paper is to compare the impact of supervised walking and resistance training upon the walking distance in PAD patients. Materials and Methods. The examination involved 50 PAD patients at the 2nd stage of the disease according to Fontaine's scale. The participants were randomly allocated to two groups: one exercising on the treadmill (n = 24) and one performing resistance exercises of lower limbs (n = 26). Results. The 12-week program of supervised rehabilitation led to a significant increase in the intermittent claudication distance measured both on the treadmill and during the 6-minute walking test...
2016: BioMed Research International
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