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https://www.readbyqxmd.com/read/28224704/advanced-glycation-end-products-regulate-anabolic-and-catabolic-activities-via-nlrp3-inflammasome-activation-in-human-nucleus-pulposus-cells
#1
Yu Song, Yan Wang, Yukun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xinghuo Wu, Liang Kang, Cao Yang
Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL-1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL-1β production in the intervertebral disc, especially in nucleus pulposus (NP) cells, are unknown. In some tissues, advanced glycation end products (AGEs), which accumulate in NP tissues and promote its degeneration, increase oxidative stress and IL-1β secretion, resulting in disorders, such as obesity, diabetes mellitus and ageing...
February 22, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28211834/is-active-design-changing-the-workplace-a-natural-pre-post-experiment-looking-at-health-behaviour-and-workplace-perceptions
#2
Lina Engelen, Josephine Chau, Erika Bohn-Goldbaum, Sarah Young, Dominique Hespe, Adrian Bauman
BACKGROUND: Active Design is a relatively new concept and evaluation on its effects on healthy behaviour is lacking. OBJECTIVE: To investigate Active Design influence on workplace physical activity, sedentary behaviour, musculoskeletal complaints, and perceptions of the workplace and productivity. METHODS: Participants (n = 118 adults) moving from 14 workplaces into a new building completed an online questionnaire pre- and post-move. The questions related to health behaviours (physical activity, sitting time and sleep); musculoskeletal issues; perceptions of the office environment; productivity; and engagement...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28201922/diagnosis-of-osteoporosis-in-rural-arctic-greenland-a-clinical-case-using-plain-chest-radiography-for-secondary-prevention-and-consideration-of-tools-for-primary-prevention-in-remote-areas
#3
Inuuteq Fleischer, Louise K Schæbel, Nadja Albertsen, Vibeke N Sørensen, Stig Andersen
CONTEXT: Osteoporosis is a frequent disease in many populations. The hallmark is fragility fractures, which are harbingers of future fractures, disability, mortality and cost on society. The occurrence increases with age, low vitamin D level and smoking. Smoking rates are high, vitamin D is low and life expectancy is rising steeply in Greenland, as is the need for focus on osteoporosis. We report a case that uses a simple and readily available tool to diagnose osteoporosis at the hospital in Sisimiut, a town of 5000 inhabitants on the west coast of Greenland...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28167195/lumbar-scoliosis-reducing-lower-back-pain-and-improving-function-in-adulthood-a-case-report-with-a-2-year-follow-up
#4
Massimiliano Polastri, Michele Romano
BACKGROUND: Lower back pain (LBP) can persist into adulthood as a sequelae of adolescent lumbar scoliosis, particularly under certain conditions influenced by aspects of bodily biomechanics and/or other factors. Here we describe the use of tailored bracing used in an adult with pre-existing lumbar scoliosis suffering from LBP. CASE DESCRIPTION: A 40-year-old female presented with acute LBP. The subject complained of acute lumbar pain exacerbated when she was upright, and when she was engaged in the normal activities of daily life...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28166873/effect-of-work-boot-type-on-work-footwear-habits-lower-limb-pain-and-perceptions-of-work-boot-fit-and-comfort-in-underground-coal-miners
#5
Jessica A Dobson, Diane L Riddiford-Harland, Alison F Bell, Julie R Steele
Lower limb injuries are highly prevalent in underground coal mining. Wearing gumboots with inadequate ankle support was thought to contribute to these injuries. Despite the uptake of leather lace-up boots, which provide more ankle support, no recent research could be found investigating the effect of this alternative work boot in underground coal mining. Consequently, this study aimed to determine whether boot type (gumboot, leather lace-up boot) influenced work footwear habits, foot problems, lower limb pain, lower back pain, or perceptions of work boot fit and comfort in underground coal miners...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28162307/-503-trauma-exposure-and-pain-severity-among-people-with-chronic-lower-back-pain-moderated-mediation-by-thought-suppression-and-social-constraints
#6
S Pegram, M Lumley, D Latsch, M Jasinski, E Schuster, J Burns
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28154826/the-outcomes-of-minimally-invasive-versus-open-posterior-approach-spinal-fusion-in-treatment-of-lumbar-spondylolisthesis-the-current-evidence-from-prospective-comparative-studies
#7
REVIEW
Ai-Min Wu, Chun-Hui Chen, Zhi-Hao Shen, Zhen-Hua Feng, Wan-Qing Weng, Shu-Min Li, Yong-Long Chi, Li-Hui Yin, Wen-Fei Ni
Purpose. To investigate the evidence of minimally invasive (MI) versus open (OP) posterior lumbar fusion in treatment of lumbar spondylolisthesis from current prospective literatures. Methods. The electronic literature database of Pubmed, Embase, and Cochrane library was searched at April 2016. The data of operative time, estimated blood loss and length of hospital stay, visual analog scale (VAS) of both lower back pain and leg pain, Oswestry disability index (ODI), SF-36 PCS (physical component scores) and SF-36 MCS (mental component scores), complications, fusion rate, and secondary surgery were extracted and analyzed by STATA 12...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28149141/are-transitional-vertebra-and-spina-bifida-occulta-related-with-lumbar-disc-herniation-and-clinical-parameters-in-young-patients-with-chronic-low-back-pain
#8
Emine Eda Kurt, Aysegul Kuçukali Turkyilmaz, Yeliz Dadali, Hatice Rana Erdem, Figen Tuncay
OBJECTIVE: Lumbosacral transitional vertebra (LSTV) and spina bifida occulta (SBO) are widespread within the lumbosacral spine. Their connection to lumbar disc herniation (LDH) and/or lower back pain has been debated in the current literature; however, there is no consensus. The purpose of this study is to evaluate the relationship between the frequency of LSTV and SBO with that of LDH among young patients with chronic lower back pain. STUDY DESIGN: Cross-sectional...
October 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28145182/yoga-could-help-people-with-chronic-lower-back-pain
#9
(no author information available yet)
Practising yoga can reduce pain and increase functional ability in people with chronic, non-specific lower back pain, suggest the results of a Cochrane Review.
February 1, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28123921/relief-of-lumbar-symptoms-after-cervical-decompression-in-patients-with-tandem-spinal-stenosis-presenting-with-primarily-lumbar-pain
#10
Daniel R Felbaum, Islam Fayed, Jeffrey J Stewart, Faheem A Sandhu
OBJECTIVE: Tandem cervical and lumbar spinal stenosis (TSS) is classically described as intermittent claudication, gait disturbance, and clinical findings of mixed myelopathy and polyradiculopathy. Rarely, patients can present with TSS manifesting in isolated lumbar pain. Several reports have demonstrated improved lumbar back pain and radiculopathy after decompressive cervical spine procedures. We present six patients with dramatic resolution of lumbar spine related symptoms after decompression of the cervical spinal cord despite presenting solely with lower back complaints...
December 24, 2016: Curēus
https://www.readbyqxmd.com/read/28121529/the-disease-burden-of-the-most-common-autoimmune-diseases
#11
Jack Mccain
By some measures, the financial and health toll from inflammatory bowel disease, rheumatoid arthritis, and psoriasis is comparable to stroke and lower back pain. Collectively, they affect about 10 million patients in the United States. They are chronic conditions characterized by immune-mediated inflammation of unknown etiology and for which there is no cure.
July 2016: Managed Care
https://www.readbyqxmd.com/read/28108318/response-inhibition-set-shifting-and-complex-executive-function-in-patients-with-chronic-lower-back-pain
#12
Rytis Masiliūnas, Dalia Vitkutė, Edgaras Stankevičius, Vaidas Matijošaitis, Kęstutis Petrikonis
OBJECTIVE: The aim of our study was to evaluate how response inhibition, set shifting, and complex executive function (represented by risky decision-making) are altered in chronic lower back pain patients. MATERIALS AND METHODS: A total of 29 patients with chronic lower back pain (CLBP >6 months) aged 49-69 years and 30 healthy volunteers matched for age, gender, and education were enrolled in a case-control study. The study was conducted in the Departments of Neurology and Neurosurgery of Panevėžys Regional Hospital, Lithuania...
January 2, 2017: Medicina
https://www.readbyqxmd.com/read/28108224/effectiveness-of-monotherapy-and-combined-therapy-with-calcitonin-and-minodronic-acid-hydrate-a-bisphosphonate-for-early-treatment-in-patients-with-new-vertebral-fractures-an-open-label-randomized-parallel-group-study
#13
Shinya Tanaka, Akira Yoshida, Shinjiro Kono, Manabu Ito
BACKGROUND: Evidence related to the effectiveness of combination drug therapy for the treatment of osteoporosis is currently considered insufficient. Therefore, this study was performed to clarify the effects of monotherapy, and combination therapy, with a bisphosphonate (minodronic acid hydrate), a bone resorption inhibitor, and calcitonin (elcatonin), which is effective for the alleviation of pain due to vertebral fractures in osteoporotic patients. METHODS: Study participants comprised of 51 female subjects with post-menopausal osteoporosis, whose main complaint was acute lower back pain caused by vertebral fractures...
January 18, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28097198/intimal-sarcoma-of-the-descending-aorta-mimicking-aortitis
#14
Angela Pucci, Andrea De Martino, Maurizio Levantino, Raffaella Berchiolli, Fulvio Basolo, Uberto Bortolotti
We describe a 74-year-old male patient with an intimal sarcoma of the descending aorta mimicking aortitis. The patient presented with lower back pain, fever, and increased C-reactive protein, erythrocyte sedimentation rate, and immunoglobulin G4 (IgG4) serum levels, together with Staphylococcus epidermidis-positive blood cultures. These findings, together with evidence of a 49-mm pseudoaneurysm of the descending thoracic aorta, caused us to suspect aortitis. However, postoperative histology and immunohistochemistry demonstrated the presence of an intimal aortic sarcoma...
August 2016: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/28088887/-improvement-of-lumbal-motor-control-and-trunkmuscle-conditions-with-a-novel-low-back-pain-prevention-exercise-program
#15
Viktória Kovácsné Bobály, Brigitta Szilágyi, Alexandra Makai, Ákos Koller, Melinda Járomi
INTRODUCTION: Ballet dancers often suffer from low back pain. AIM: Low back pain can be reduced by strengthening the core muscles with the help of a special exercise program. MATERIALS AND METHODS: In the study 62 ballet dancer women (average age: 14.89 ± 1.21 years) were included. Intervention group: n = 30 participant, average age: 14.86 ± 1.00 years, control group: n = 32 participant, average age: 14.91 ± 1.37 years. We examined the pain intensity that occurs during training with visual analog scale, the habitual posture with photogrammetry, the abdominal muscle strength with Kraus-Weber test, the static muscle strength of the trunk muscles with core test and the lumbar motor control with leg lowering test...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28081028/second-order-peer-reviews-of-clinically-relevant-articles-for-the-physiatrist-early-physical-therapy-vs-usual-care-in-patients-with-recent-onset-low-back-pain-fritz-jm-magel-js-mcfadden-m-et-al-jama-2015-physical-therapy-may-not-help-acute-lower-back-pain-sufferers
#16
Venu Akuthota, Benjamin Marshall, Paul E Mintken, Margaret Schenkman, Dinesh Kumbhare
No abstract text is available yet for this article.
January 9, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28078869/high-level-laser-therapy-for-the-treatment-of-lower-back-pain-clinical-efficacy-and-comparison-of-different-wavelengths
#17
A Notarnicola, G Maccagnano, S Tafuri, M F Gallone, L Moretti, B Moretti
High energy laser therapy (HELT) could be a new alternative treatment for lower back pain (LBP), which is a significant public health problem. Nevertheless, differences between the various light waves of HELT have not yet been fully researched. Sixty-six patients with lower back pain were treated using a high energy laser therapy. They were randomized into three different protocols which differed according to wave length (650 nm, 810 nm and TRIAX, which is simultaneous emission of 810 nm, 980 nm e 1064 nm)...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28076822/an-in-vitro-analysis-of-the-size-and-shape-of-cryolesions-for-facet-joint-denervation
#18
T Wolter, Y Bozhkov, S M Knoeller
OBJECTIVES: Lumbar facet joint syndrome (LFJS) is the cause of lower back pain in 15-54% of the patients. Clinical studies of cryotherapy for LFJS have reported promising outcomes. However, few studies have focused on the technical aspects of cryoneurolysis for LFJS. The aim of the study was to determine the size and shape of cryolesions in vitro and to determine how they are affected by the duration of freezing, size of the cryoprobe and distance and angulation to an osseous boundary layer...
February 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28074248/pregnancy-associated-osteoporosis-a-case-control-study
#19
P Hadji, J Boekhoff, M Hahn, L Hellmeyer, O Hars, I Kyvernitakis
: The etiology and underlying mechanisms of pregnancy-associated osteoporosis (PAO) are still unknown, since no systematic analyses exist. Our results indicate that PAO is a heterogeneous, rare but severe disease including a substantial number of fractures with a significant delay from first symptom to diagnose. INTRODUCTION: Pregnancy-associated osteoporosis (PAO) is a rare but severe type of premenopausal osteoporosis. Most common symptom includes acute lower back pain due to vertebral fracture predominantly occurring in the last trimester of pregnancy or immediately postpartum...
January 10, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28072802/efficacy-of-adjuvant-10-hypertonic-saline-in-transforaminal-epidural-steroid-injection-a-retrospective-analysis
#20
Eun Young Joo, Won Uk Koh, Seong-Soo Choi, Jae-Hyung Choi, Ho-Soo Ahn, Hye Joo Yun, Jin-Woo Shin
BACKGROUND: Chronic lower back pain with or without radiculopathy represents an important medical, social, and economic problem. Many treatment modalities and techniques, including surgery and epidural administration of steroids, have been used to manage this pain. Hypertonic saline, which has been used as an adjunct to percutaneous epidural adhesiolysis, can also be injected via a transforaminal approach in expectation of longer-lasting effects. OBJECTIVES: This study aimed to determine the effect of adding hypertonic saline to conventional transforaminal epidural steroid injections (TFEI) to provide pain relief for chronic radiculopathy patients...
January 2017: Pain Physician
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