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https://www.readbyqxmd.com/read/28912408/-results-of-a-drug-use-survey-of-filgrastim-biosimilar-1-filgrastim-bs-syringe-for-inj-mochida-and-f
#1
Tsukasa Teshima, Nao Takigawa, Yuki Makita, Chinatsu Kushiya
With the aim of evaluating the safety and efficacy of filgrastim biosimilar 1(Filgrastim BS syringe for Inj. "MOCHIDA"and "F"), we conducted a drug use results survey of this product for its indications, including mobilization of hematopoietic stem cells into peripheral blood and chemotherapy-induced neutropenia. Of the 518 cases enrolled between August 2013 and July 2015, 495 were selected to be subjects of our safety and efficacy evaluations. 37 cases (7.47%)experienced side effects, which were mainly lower back pain(19, 3...
September 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28904718/-intrauterine-device-about-a-rare-complication-and-literature-review
#2
Adil Kallat, Ahmed Ibrahimi, Otheman Fahsi, Hachem El Sayegh, Ali Iken, Lounis Benslimane, Yassine Nouini
The intrauterine device (IUD) is the most common contraceptive method used in the world. Transuterine migration is a rare complication, accounting for 1/350 - 1/10000 insertions in the literature. We report the case of a 40-year old patient, who had had an IUD insertion 12-year before, presenting with pelvic and right lower back pain associated with intermittent hematuria and burning during urination. Radiological assessment showed calcific deposits on intra bladder IUD. The patient underwent cystostomy, without any difficulty, allowing stone and IUD extraction...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28890010/lumbosacral-subdural-hematoma-following-glioblastoma-multiforme-resection-possible-radiographic-evidence-for-the-downward-migration-of-intracranial-blood
#3
Gabriella M Paisan, Thomas J Buell, Daniel Raper, Ashok Asthagiri
Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors. We report a case of a 75-year-old male who developed a symptomatic lumbosacral SSDH after undergoing resection of a right temporal glioblastoma multiforme. The patient subsequently recovered and was discharged home. Over the next two weeks he developed progressively worsening symptoms of lower back pain, lower extremity weakness, and urinary retention...
September 7, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28878472/effects-of-the-centrifugal-contraction-exercise-of-the-rectus-abdominis-accompanied-with-the-isometric-exercise-of-the-transversus-abdominis-on-pain-and-balance-of-lower-back-pain-patients
#4
Jung-Ho Lee
[Purpose] The current study attempted to examine the effects of centrifugal contraction exercise of the rectus abdominis during the isometric contraction of the transversus abdominis on pain and balance of patients with chronic back pain. [Subjects and Methods] The subjects included thirty patients who were diagnosed with back pain due to causes other than neurological by a specialist after conducting a medical precision diagnosis. The experiment was performed after evenly dividing the subjects into two groups, namely, control and experimental, using a random method...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28878454/effects-of-pelvic-compression-belts-on-the-kinematics-and-kinetics-of-the-lower-extremities-during-sit-to-stand-maneuvers
#5
Jong Moon Kim, Hyun Dong Je, Hyeong-Dong Kim
[Purpose] To investigate the effects of a pelvic compression belt (PCB) and chair height on the kinematics and kinetics of the lower extremity during sit-to-stand (STS) maneuvers in healthy people. [Subjects and Methods] Twenty-two people participated in this study. They were required to perform STS maneuvers under four conditions. Hip joint moment and angular displacement of the hip, knee, and ankle were measured. A PCB was also applied below the anterior superior iliac spine. [Results] The angular displacement of the ankle joint increased while performing STS maneuvers from a normal chair with a PCB in phase 1, and decreased during phase 2 when performing STS maneuvers from a high chair...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28874985/an-updated-overview-of-low-back-pain-management-in-primary-care
#6
REVIEW
Jae-Young Hong, Kwang-Sup Song, Jae Hwan Cho, Jae Hyup Lee
Currently, guidelines for lower back pain (LBP) treatment are needed. We reviewed the current guidelines and high-quality articles to confirm the LBP guidelines for the Korean Society of Spine Surgery. We searched available databases for high-quality articles in English on LBP published from 2000 to the present year. Literature searches using these guidelines included studies from MEDLINE, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, and Embase. We analyzed a total of 132 randomized clinical trials, 116 systematic reviews, 9 meta-analyses, and 4 clinical guideline reviews...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28874973/inhibiting-vascular-endothelial-growth-factor-in-injured-intervertebral-discs-attenuates-pain-related-neuropeptide-expression-in-dorsal-root-ganglia-in-rats
#7
Jun Sato, Kazuhide Inage, Masayuki Miyagi, Yoshihiro Sakuma, Kazuyo Yamauchi, Masao Koda, Takeo Furuya, Junichi Nakamura, Miyako Suzuki, Go Kubota, Yasuhiro Oikawa, Takeshi Sainoh, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Kazuhisa Takahashi, Seiji Ohtori, Sumihisa Orita
STUDY DESIGN: An experimental animal study. PURPOSE: To evaluate effects of anti-vascular endothelial growth factor (VEGF) on the content and distribution of the calcitonin gene-related peptide (CGRP) in the dorsal ganglia in a rat model. OVERVIEW OF LITERATURE: Increased expression of VEGF in degenerative disc disease increases the levels of inflammatory cytokines and nerve ingrowth into the damaged discs. In animal models, increased levels of VEGF can persist for up to 2 weeks after an injury...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28868091/non-invasive-raman-spectroscopy-and-quantitative-real-time-pcr-distinguish-among-undifferentiated-human-mesenchymal-stem-cells-and-redifferentiated-nucleus-pulposus-cells-and-chondrocytes-in-vitro
#8
Franziska Ehlicke, Natascha Köster, Denise Salzig, Peter Czermak
BACKGROUND: The most common cause of lower back pain is the pathological degeneration of the nucleus pulposus (NP). Promising NP regeneration strategies involving human mesenchymal stem cells (hMSCs) would require specific markers to confirm successful differentiation into the NP lineage and to distinguish the articular cartilage (AC). OBJECTIVE: We sought specific NP mRNA markers that are upregulated in native NP cells but not in dedifferentiated NP cells, undifferentiated hMSCs or chondrocytes...
2017: Open Biomedical Engineering Journal
https://www.readbyqxmd.com/read/28864165/public-reporting-of-mri-of-the-lumbar-spine-for-low-back-pain-and-changes-in%C3%A2-clinical-documentation
#9
Jonathan A Flug, Kimberly E Lind
OBJECTIVE: OP-8 is the Medicare imaging efficiency metric for MRI of the lumbar spine for low back pain in the outpatient hospital. We studied trends in exclusion criteria coding over time by site of service after implementation of OP-8 to evaluate provider's response to public reporting. MATERIALS AND METHODS: We conducted a secondary data analysis using the Medicare Limited Data Set 5% sample for beneficiaries with MRI lumbar spine and lower back pain during 2009 to 2014...
August 30, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28858108/effect-of-bone-mineral-density-on-lumbar-discs-in-young-adults-a-case-control-study
#10
Nese Keser, Arzu Atici, Erhan Celikoglu, Pinar Akpinar, Ali F Ramazanoglu, İlknur Aktas
Bone mineral density (BMD) might be a risk factor for lumbar disc herniation (LDH) in young adults, but there is not enough data concerning this effect. Several studies have been performed on elderly and osteoporotic patients. Thus, we aimed to investigate the effect of BMD on the etiopathogenesis of LDH in young adults.One hundred patients (mean age: 38.45 ± 8.92 years; 50 men and 50 women) were enrolled this case-control study and classified into 2 groups, as follows. The case group (G-I) included 50 patients with symptomatic LDH who were hospitalized in the Physical Medicine and Rehabilitation Clinic, and the control group (G-II) included 50 patients with lower back pain but no finding of LDH detected using magnetic resonance imaging...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28845185/comparison-of-deep-tissue-massage-and-therapeutic-massage-for-lower-back-pain-disease-activity-and-functional-capacity-of-ankylosing-spondylitis-patients-a-randomized-clinical-pilot-study
#11
Mateusz Wojciech Romanowski, Maja Špiritović, Radosław Rutkowski, Adrian Dudek, Włodzimierz Samborski, Anna Straburzyńska-Lupa
OBJECTIVES: This study aims to compare the effectiveness of deep tissue massage (DTM) and therapeutic massage (TM) in the management of ankylosing spondylitis (AS) patients. MATERIALS AND METHODS: This was a small, randomized clinical pilot study. Subjects were 27 men with diagnosed AS, randomly assigned to DTM group or TM group. Subjects in each group had 10 sessions of massage. Outcomes included the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), Modified Schober Test, Finger to Floor Test, chest expansion, and pain intensity of lower back...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28844304/46-year-old-man-with-lower-back-pain
#12
Daniel S Childs, Sean I Tracy, Uma Thanarajasingam
No abstract text is available yet for this article.
August 22, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28842990/migraine-prophylaxis-and-acute-treatment-patterns-among-commercially-insured-patients-in-the-united-states
#13
J Michael Woolley, Machaon M Bonafede, Brett A Maiese, Robert A Lenz
OBJECTIVES: To describe prophylactic and acute medication treatment patterns, including timing, medication type, and duration of use in migraine patients initiating prophylaxis. BACKGROUND: Patients with migraine can be treated with acute and prophylactic therapies. Current treatment options for migraine prophylaxis are associated with poor tolerability and low adherence and persistence. METHODS: This retrospective cohort study used the Truven Health Analytics MarketScan(®) Research Databases to identify adults in the United States with a migraine diagnosis who initiated migraine prophylactic medication (index event) between January 1, 2008, and December 31, 2011...
August 26, 2017: Headache
https://www.readbyqxmd.com/read/28840995/novel-4-bp-intronic-deletion-c-1560-3_1560-6del-in-lemd3-in-a-korean-patient-with-osteopoikilosis
#14
In Young Yoo, Ju Sun Song, Chang Seok Ki, Jong Won Kim, Hoon Suk Cha, Yong Ki Min
Osteopoikilosis is an autosomal dominant bone disorder characterized by symmetric multiple osteosclerotic lesions throughout the axial and appendicular skeleton. Pathogenic variants in the LEMD3 have been identified as the cause of osteopoikilosis. LEMD3 encodes an inner nuclear membrane protein that interacts with bone morphogenetic protein (BMP) and transforming growth factor (TGF)-β pathways. We report the case of a 19-year-old man presenting with lower back pain and sciatica. His radiograph revealed bilateral and symmetrical multiple osteosclerotic bone lesions in both scapular areas...
November 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28839309/knowledge-around-back-pain-and-spinal-disorders-among-saudi-patients-a-cross-sectional-study
#15
Waleed Mohammad Awwad, Saud Mohammed Alfayez, Abdullah Nasser Bin Dous, Qais Abdulmohsin Alrabiei, Abdullah Abdulaziz Altowim, Abdulaziz Saud Almutair, Orfan Arafah
OBJECTIVE: To assess the knowledge of patients about low back pain and spinal disorders. METHODS: This cross-sectional study was conducted at King Saud University, Riyadh, Saudi Arabia, from December 2015 to February 2016, and comprised patients presenting with lower back pain. The low back pain knowledge questionnaire was translated to Arabic and distributed, after adding more questions, among patients. The scores were calculated as per the published guidelines...
August 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28836862/impact-of-uterine-fibroid-symptoms-on-health-related-quality-of-life-of-us-women-evidence-from-a-cross-sectional-survey
#16
Ahmed M Soliman, Mary Kay Margolis, Jane Castelli-Haley, Mahesh J Fuldeore, Charlotte D Owens, Karin S Coyne
BACKGROUND: Uterine fibroids (UF) are associated with significant health-related quality of life (HRQL) impact. This study examined the impact of UF symptoms on HRQL. METHODS: An online cross-sectional survey of 18 to 49 year US women was conducted and collected demographics, UF prevalence, symptoms, and HRQL using the UFS-QOL. Descriptive statistics were used to examine the impact of symptom presence, severity, bothersomeness, and number of UF symptoms on HRQL...
August 24, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28835212/spondylodiscitis-due-to-parvimonas-micra-diagnosed-by-the-melting-temperature-mapping-method-a-case-report
#17
Yoshitsugu Higashi, Shigeki Nakamura, Hideki Niimi, Tomohiro Ueno, Kaoru Matsumoto, Koyomi Kawago, Ippei Sakamaki, Isao Kitajima, Yoshihiro Yamamoto
BACKGROUND: It has been suggested that more than 100 bacterial species can be identified using only seven universal bacterial primer sets in the melting temperature (Tm) mapping method and that these findings can be obtained within 3 h of sterile site collection. CASE PRESENTATION: A 67-year-old Japanese man with type 2 diabetes visited our hospital complaining of progressive lower back pain for 2 months. The patient was suspected to have spondylodiscitis on magnetic resonance imaging of the spine...
August 23, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28828331/effects-of-a-complex-intervention-exercise-program-on-lumbar-extension-strength-and-stability-in-female-patients-with-lower-back-pain
#18
Soonyoung Kim, Kyoungkyu Jeon
No abstract text is available yet for this article.
June 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28817780/us-internists-awareness-and-use-of-overtreatment-guidelines-a-national-survey
#19
Kira L Ryskina, Eric S Holmboe, Elizabeth Bernabeo, Rachel M Werner, Judy A Shea, Judith A Long
OBJECTIVES: To assess physician views and perceived adoption of overtreatment guidelines and measure whether adoption of these guidelines influenced the recommendation of a targeted service. STUDY DESIGN: A cross-sectional survey mailed from July 2014 to January 2015 to 902 internists who completed residency between 2003 and 2013, randomly selected from the American Medical Association Masterfile. METHODS: Poisson regression was used to model the rate of recommending a targeted service included in the guidelines, based on the level of guideline adoption...
July 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28795908/structural-equation-modelling-of-lower-back-pain-due-to-whole-body-vibration-exposure-in-the-construction-industry
#20
Vitharanage Hashini Paramitha Vitharana, Thanwadee Chinda
Whole body vibration (WBV) exposure is a health hazard among workers, causing lower back pain (LBP) in the construction industry. This study examines key factors affecting LBP due to WBV exposure using the exploratory factor analysis and structural equation modelling. The results confirm five key factors, which are equipment, job-related, organizational, personal, and social- context, with their 17 associated items. The organizational factor is found the most important factor, as it influences the other four factors...
August 10, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
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