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https://www.readbyqxmd.com/read/28326305/implications-for-a-stem-cell-regenerative-medicine-based-approach-to-human-intervertebral-disk-degeneration
#1
REVIEW
Petra Kraus, Thomas Lufkin
The human body develops from a single cell, the zygote, the product of the maternal oocyte and the paternal spermatozoon. That 1-cell zygote embryo will divide and eventually grow into an adult human which is comprised of ~3.7 × 10(13) cells. The tens of trillions of cells in the adult human can be classified into approximately 200 different highly specialized cell types that make up all of the different tissues and organs of the human body. Regenerative medicine aims to replace or restore dysfunctional cells, tissues and organs with fully functional ones...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28302624/a-woman-with-lower-back-pain
#2
Tobenna J Oputa, Jamie A'Court
No abstract text is available yet for this article.
March 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28301442/effect-of-ankle-mobility-and-segment-ratios-on-trunk-lean-in-the-barbell-back-squat
#3
Emil Isager Fuglsang, Anders Stampe Telling, Henrik Sørensen
The barbell back squat is a popular exercise used for both performance enhancing and rehabilitation purposes. However, injuries are common and people with a history of lower back pain are especially vulnerable. Past studies have shown that higher trunk angles (less forward lean) generate less stress on the lower back; thus, it seems appropriate to investigate the factors presumed to influence the trunk angle. Therefore, the aim in this study was to investigate how ankle mobility and the segment ratios between the thoracic spine, thighs and shanks influence the trunk angle in the back squat...
March 13, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28290751/comparison-of-thoracic-and-lumbar-erector-spinae-muscle-activation-before-and-after-a-golf-practice-session
#4
Graeme G Sorbie, Fergal M Grace, Yaodong Gu, Julien S Baker, Ukadike C Ugbolue
Lower back pain is commonly associated with golfers. The study aimed: to determine whether thoracic- and lumbar-erector-spinae muscle display signs of muscular fatigue after completing a golf practice session, and to examine the effect of the completed practice session on club head speed, ball speed and absolute carry distance performance variables. Fourteen right-handed male golfers participated in the laboratory-based-study. Surface electromyography (EMG) data was collected from the lead and trail sides of the thoracic- and lumbar-erector-spinae muscle...
March 14, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28288602/is-being-a-regular-player-with-fewer-teammates-associated-with-musculoskeletal-pain-in-youth-team-sports-a-cross-sectional-study
#5
Takafumi Abe, Masamitsu Kamada, Jun Kitayuguchi, Shinpei Okada, Yoshiteru Mutoh, Yuji Uchio
BACKGROUND: Musculoskeletal pain (MSP) is a commonly reported symptom in youth sports players. Some sports-related risk factors have been reported, but previous studies on extrinsic risk factors did not focus on management of team members (e.g., regular or non-regular players, number of players) for reducing sports-related MSP. This study aimed to examine the association of playing status (regular or non-regular players) and team status (fewer or more teammates) with MSP in youth team sports...
March 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28288047/bertolotti-syndrome-demonstrated-on-18f-naf-pet-ct
#6
Sharjeel Usmani, Najeeb Ahmed, Fahad Marafi, Fareeda Al Kandari
Bertolotti syndrome is a form of low-back pain associated with lumbosacral transitional vertebrae. We report a case of a 34-year-old woman with breast cancer presented with severe low-back pain. F-NaF PET/CT demonstrates increased radiotracer uptake at the transverse-sacral articulation corresponding to hemisacralized left transverse process of L5 vertebra. Increased tracer uptake in patients with lumbosacral transitional vertebrae seems to correlate with lower-back pain symptoms. F-NaF PET/CT can be useful in evaluation of some uncommon causes of low-back pain...
March 10, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28288044/the-accessory-sacroiliac-joint-diagnosed-with-bone-spect-ct
#7
Ji-Hun Kang, Min-Woo Kim, Eun Ha Moon, Young Jun Kim, Ki Pi Yu
The accessory sacroiliac (SI) joint is not rare and can be one of the causes of lower back pain. We present a case of a 35-year-old woman with chronic lower back pain. Conventional radiography was equivocal, and bone scintigraphy showed a focus of mildly increased uptake in left SI joint region. SPECT/CT revealed increased uptakes in the accessory articulations between both sacral alae and iliac bones, and confirmed the diagnosis of accessory SI joint. This case illustrates the SPECT/CT findings of the accessory SI joint...
March 10, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28269810/comparison-of-trunk-electromyographic-muscle-activity-depends-on-sitting-postures
#8
DongGeon Lee, SeoJeong Yu, SunHae Song, Se-Han Lee, SeungHeon An, Hwi-Young Cho, Ki-Hun Cho, GyuChang Lee
BACKGROUND: Different postural positions can be characterized by the activation and relative contributions of different postural muscles, and may variously contribute to the recovery from or worsening of chronic lower back pain. OBJECTIVE: The present study aimed to investigates trunk muscle activities in four types of seated postures: cross-legged, long, side, and W-shaped. METHODS: Eight healthy adults participated in the study. Trunk muscle activities of the external oblique (EO), rectus abdominis (RA), latissimus dorsi (LD), and erector spinae (ES) muscles in each of the sitting postures including cross-legged, long, side, and W-shaped were collected utilizing surface electromyography (sEMG)...
February 27, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28269804/the-application-of-a-feasible-exercise-training-program-in-the-office-setting
#9
Ardalan Shariat, Eddie T C Lam, Mehdi Kargarfard, Shamsul B M Tamrin, Mahmoud Danaee
BACKGROUND: Previous research support the claim that people who work in offices and sit for a long time are particularly prone to musculoskeletal disorders. OBJECTIVE: The main objective of this paper is to introduce an exercise training program designed to decrease muscle stiffness and pain that can be performed in the office setting. METHODS: Forty healthy office workers (age: 28±5.3 years old; body mass: 87.2±10.2 kg; height: 1.79±0...
February 27, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28266756/high-frequency-spinal-cord-stimulation-in-surgery-na%C3%A3-ve-patients-a-prospective-single-center-study
#10
Sebastian A Ahmadi, Jan Vesper, Stefan Schu, Philipp J Slotty
INTRODUCTION: A multitude of evidence supporting the beneficial effects of spinal cord stimulation (SCS) in patients suffering from chronic pain syndromes following spinal surgery has been published in the last decade. Evidence is scarce, however, for the use of high frequency SCS (HF-SCS) in the treatment of surgery naïve patients suffering from lower back pain (LBP). METHODS: From June 2014 to April 2015, we prospectively enrolled patients suffering from LBP alone or in conjunction with leg pain in a trial of HF-SCS...
March 7, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28247084/anatomy-of-the-sacral-hiatus-and-its-clinical-relevance-in-caudal-epidural-block
#11
Hassan Bagheri, Figen Govsa
PURPOSE: Caudal epidural anesthesia (CEB) is widely used for the prevention of chronic lower back pain, the control of intraoperative analgesia such as genitourinary surgery and labor pain cases in sacral epidural space approach for the implementation of analgesia. CEB is an anesthetic solution used into the sacral canal via sacral hiatus (SH). For optimal access into the sacral epidural space, detailed anatomical landmarks of SH are required. This study aims at exploring the anatomical structures and differences of the SH by using the sacral bone as a guide point to failure criteria for reviewing the caudal epidural anesthesia and improving the criteria for success in practice...
February 28, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28246488/factors-for-predicting-favorable-outcome-of-percutaneous-epidural-adhesiolysis-for-lumbar-disc-herniation
#12
Sang Ho Moon, Jae Il Lee, Hyun Seok Cho, Jin Woo Shin, Won Uk Koh
Background. Lower back pain is a common reason for disability and the most common cause is lumbar disc herniation. Percutaneous epidural adhesiolysis has been applied to relieve pain and increase the functional capacity of patients who present this condition. Objectives. In this study, we retrospectively evaluated the factors which predict the outcome of percutaneous epidural adhesiolysis in patients who were diagnosed with lumbar disc herniation. Methods. Electronic medical records of patients diagnosed with lumbar disc herniation who have received percutaneous epidural adhesiolysis treatment were reviewed...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28224704/advanced-glycation-end-products-regulate-anabolic-and-catabolic-activities-via-nlrp3-inflammasome-activation-in-human-nucleus-pulposus-cells
#13
Yu Song, Yan Wang, Yukun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xinghuo Wu, Liang Kang, Cao Yang
Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL-1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL-1β production in the intervertebral disc, especially in nucleus pulposus (NP) cells, are unknown. In some tissues, advanced glycation end products (AGEs), which accumulate in NP tissues and promote its degeneration, increase oxidative stress and IL-1β secretion, resulting in disorders, such as obesity, diabetes mellitus and ageing...
February 22, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28211834/is-active-design-changing-the-workplace-a-natural-pre-post-experiment-looking-at-health-behaviour-and-workplace-perceptions
#14
Lina Engelen, Josephine Chau, Erika Bohn-Goldbaum, Sarah Young, Dominique Hespe, Adrian Bauman
BACKGROUND: Active Design is a relatively new concept and evaluation on its effects on healthy behaviour is lacking. OBJECTIVE: To investigate Active Design influence on workplace physical activity, sedentary behaviour, musculoskeletal complaints, and perceptions of the workplace and productivity. METHODS: Participants (n = 118 adults) moving from 14 workplaces into a new building completed an online questionnaire pre- and post-move. The questions related to health behaviours (physical activity, sitting time and sleep); musculoskeletal issues; perceptions of the office environment; productivity; and engagement...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28201922/diagnosis-of-osteoporosis-in-rural-arctic-greenland-a-clinical-case-using-plain-chest-radiography-for-secondary-prevention-and-consideration-of-tools-for-primary-prevention-in-remote-areas
#15
Inuuteq Fleischer, Louise K Schæbel, Nadja Albertsen, Vibeke N Sørensen, Stig Andersen
CONTEXT: Osteoporosis is a frequent disease in many populations. The hallmark is fragility fractures, which are harbingers of future fractures, disability, mortality and cost on society. The occurrence increases with age, low vitamin D level and smoking. Smoking rates are high, vitamin D is low and life expectancy is rising steeply in Greenland, as is the need for focus on osteoporosis. We report a case that uses a simple and readily available tool to diagnose osteoporosis at the hospital in Sisimiut, a town of 5000 inhabitants on the west coast of Greenland...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28167195/lumbar-scoliosis-reducing-lower-back-pain-and-improving-function-in-adulthood-a-case-report-with-a-2-year-follow-up
#16
Massimiliano Polastri, Michele Romano
BACKGROUND: Lower back pain (LBP) can persist into adulthood as a sequelae of adolescent lumbar scoliosis, particularly under certain conditions influenced by aspects of bodily biomechanics and/or other factors. Here we describe the use of tailored bracing used in an adult with pre-existing lumbar scoliosis suffering from LBP. CASE DESCRIPTION: A 40-year-old female presented with acute LBP. The subject complained of acute lumbar pain exacerbated when she was upright, and when she was engaged in the normal activities of daily life...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28166873/effect-of-work-boot-type-on-work-footwear-habits-lower-limb-pain-and-perceptions-of-work-boot-fit-and-comfort-in-underground-coal-miners
#17
Jessica A Dobson, Diane L Riddiford-Harland, Alison F Bell, Julie R Steele
Lower limb injuries are highly prevalent in underground coal mining. Wearing gumboots with inadequate ankle support was thought to contribute to these injuries. Despite the uptake of leather lace-up boots, which provide more ankle support, no recent research could be found investigating the effect of this alternative work boot in underground coal mining. Consequently, this study aimed to determine whether boot type (gumboot, leather lace-up boot) influenced work footwear habits, foot problems, lower limb pain, lower back pain, or perceptions of work boot fit and comfort in underground coal miners...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28162307/-503-trauma-exposure-and-pain-severity-among-people-with-chronic-lower-back-pain-moderated-mediation-by-thought-suppression-and-social-constraints
#18
S Pegram, M Lumley, D Latsch, M Jasinski, E Schuster, J Burns
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28154826/the-outcomes-of-minimally-invasive-versus-open-posterior-approach-spinal-fusion-in-treatment-of-lumbar-spondylolisthesis-the-current-evidence-from-prospective-comparative-studies
#19
REVIEW
Ai-Min Wu, Chun-Hui Chen, Zhi-Hao Shen, Zhen-Hua Feng, Wan-Qing Weng, Shu-Min Li, Yong-Long Chi, Li-Hui Yin, Wen-Fei Ni
Purpose. To investigate the evidence of minimally invasive (MI) versus open (OP) posterior lumbar fusion in treatment of lumbar spondylolisthesis from current prospective literatures. Methods. The electronic literature database of Pubmed, Embase, and Cochrane library was searched at April 2016. The data of operative time, estimated blood loss and length of hospital stay, visual analog scale (VAS) of both lower back pain and leg pain, Oswestry disability index (ODI), SF-36 PCS (physical component scores) and SF-36 MCS (mental component scores), complications, fusion rate, and secondary surgery were extracted and analyzed by STATA 12...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28149141/are-transitional-vertebra-and-spina-bifida-occulta-related-with-lumbar-disc-herniation-and-clinical-parameters-in-young-patients-with-chronic-low-back-pain
#20
Emine Eda Kurt, Aysegul Kuçukali Turkyilmaz, Yeliz Dadali, Hatice Rana Erdem, Figen Tuncay
OBJECTIVE: Lumbosacral transitional vertebra (LSTV) and spina bifida occulta (SBO) are widespread within the lumbosacral spine. Their connection to lumbar disc herniation (LDH) and/or lower back pain has been debated in the current literature; however, there is no consensus. The purpose of this study is to evaluate the relationship between the frequency of LSTV and SBO with that of LDH among young patients with chronic lower back pain. STUDY DESIGN: Cross-sectional...
October 2016: Eurasian Journal of Medicine
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