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https://www.readbyqxmd.com/read/29782338/chinese-patients-with-p-ala172phe-related-pfeiffer-syndrome-a-case-and-literature-review
#1
Shirely Sze Wing Cheng, Ivan Fai-Man Lo, Ho-Ming Luk
No abstract text is available yet for this article.
May 18, 2018: Clinical Dysmorphology
https://www.readbyqxmd.com/read/29781482/stabilization-of-organometallic-halide-perovskite-nanocrystals-in-aqueous-solutions-and-their-applications-in-copper-ion-detection
#2
Chunqing Ma, Ming-Fai Lo, Chun-Sing Lee
Stabilization of two-dimensional (2D) PEA2PbI4 (PEA is phenethylammonium) perovskite nanocrystals (PNCs) in water is achieved. By inhibiting the desorption process, the PNCs show exceptional stability for more than 2 months in PEA+ aqueous solutions. Stabilized PNCs are successfully applied for probing Cu2+ in aqueous solution.
May 21, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29780856/the-role-of-meaning-in-life-for-the-quality-of-life-of-community-dwelling-chinese-elders-with-low-socioeconomic-status
#3
Raymond Chi-Fai Chui
Objectives: There is limited research on the meaning in life among Chinese elders. This study aims to examine the association among functional disabilities, meaning in life, social network, and quality of life in community-dwelling Chinese elders with low socioeconomic status. Methods: A cross-sectional survey was used to collect data from 339 poor community-dwelling Chinese elders aged 60 and above. Results: The results showed that meaning in life and social network were significantly related to quality of life...
January 2018: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/29780619/hip-arthroscopy-for-femoroacetabular-impingement
#4
Rima Nasser, Benjamin Domb
The purpose of this article is to give a general overview of femoroacetabular impingement (FAI) and how it could be treated arthroscopically, with some details about indications, the procedure itself and some of the complications associated with the surgery.FAI is a dynamic condition of the hip that can be a source of pain and disability and could potentially lead to arthritis.When symptomatic, and if conservative treatment fails, FAI can be addressed surgically.The goal of surgical treatment for FAI is to recreate the spherical contour of the femoral head, improve femoral offset, normalize coverage of the acetabulum, repair/reconstruct chondral damage and repair/reconstruct the labrum to restore normal mechanics and joint sealing...
April 2018: EFORT Open Reviews
https://www.readbyqxmd.com/read/29777250/prevalence-of-temporomandibular-disorders-in-patients-with-hashimoto-thyroiditis
#5
Alina Grozdinska, Elisabeth Hofmann, Matthias Schmid, Ursula Hirschfelder
OBJECTIVES: Autoimmune thyroid disease (AITD), also known as Hashimoto thyroiditis (HT), is a degenerative inflammatory disease with high prevalence among women and has been associated with fibromyalgia and widespread chronic pain. The goal was to determine the frequency of temporomandibular disorders (TMD) in patients with HT. METHODS: In all, 119 women (age 19-60 years) were divided into a study (52 women diagnosed with HT) and a control (67 healthy individuals, of which 15 were excluded) group...
May 17, 2018: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/29774150/the-effect-of-off-hours-hospital-admission-on-mortality-and-clinical-outcomes-for-patients-with-upper-gastrointestinal-hemorrhage-a-systematic-review-and-meta-analysis-of-20-cohorts
#6
Xian Feng Xia, Philip Wai Yan Chiu, Kelvin Kam Fai Tsoi, Francis Ka Leung Chan, Joseph Jao Yiu Sung, James Yun Wong Lau
Objective: The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods: Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to identify eligible records for inclusion in this meta-analysis. A random-effects model was applied. Results: Twenty cohort studies were included for analysis...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29768998/tuber-lectins-with-potentially-exploitable-bioactivities
#7
Randy Chi Fai Cheung, Tzi Bun Ng, Jack Ho Wong, Ryno Naude, Krzysztof Rolka, Tak Fu Tse, Helen Chan, Ryan Tse, Stephen Cho Wing Sze
Lectins are a group of proteins or glycoproteins with various potentially exploitable bioactivities and have been capturing more interest recently. They have been isolated and reported from various tissues of a diversity of plant species. Tubers are modified and enlarged plant structures derived from stems or roots that are used for nutrient storage and asexual reproduction. A number of plants such as yam, taro and potato are grown for their edible tubers, and lectins are found to be one of the major storage proteins...
May 16, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29766174/efficient-nitrogen-fixation-to-ammonia-on-mxenes
#8
Mengmeng Shao, Yangfan Shao, Wenzhou Chen, Kin Long Ao, Rui Tong, Qing Zhu, Iat Neng Chan, Weng Fai Ip, Xingqiang Shi, Hui Pan
Active catalysts for nitrogen fixation (N2-fixation) have been widely pursued through constant efforts for industrial applications. Here, we report a family of catalysts, MXenes (M2X: M = Mo, Ta, Ti, and W; X = C and N), for application in N2-fixation based on density functional theory calculations. We find that the catalytic performance of MXenes strongly depends on the reaction energy in each reaction step. More exothermic steps lead to higher catalytic performance in the course of N2-fixation. We show that the reaction energy in N2-fixation is strongly affected by the charge transfer: (1) if N atoms gain more electrons in a step, the reaction is exothermic with a larger reaction energy; (2) if N atoms lose electrons in a step, the reaction is endothermic in general...
May 16, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29761113/differences-in-hip-joint-biomechanics-and-muscle-activation-in-individuals-with-femoroacetabular-impingement-compared-with-healthy-asymptomatic-individuals-is-level-ground-gait-analysis-enough
#9
Derek J Rutherford, Janice Moreside, Ivan Wong
Background: Femoroacetabular impingement (FAI) is a recognized cause of hip and groin pain and a significant factor in hip joint function during sport. Objective tests for understanding hip function are lacking in this population. Purpose: To determine whether biomechanical and electromyographic features of hip function during level-ground walking differ between a group diagnosed with FAI and those with no symptoms of FAI. Study Design: Controlled laboratory study...
May 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29758383/does-size-matter-venom-proteomic-and-functional-comparison-between-night-adder-species-viperidae-causus-with-short-and-long-venom-glands
#10
Francisco C P Coimbra, James Dobson, Christina N Zdenek, Bianca Op den Brouw, Brett Hamilton, Jordan Debono, Paul Masci, Nathaniel Frank, Lilin Ge, Hang Fai Kwok, Bryan G Fry
Night adders (Causus species within the Viperidae family) are amphibian specialists and a common source of snakebite in Africa. Some species are unique in that they have the longest venom glands of any viper, extending approximately 10% of the body length. Despite their potential medical importance and evolutionary novelty, their venom has received almost no research attention. In this study, venoms from a short-glanded species (C. lichtensteinii) and from a long-glanded species (C. rhombeatus) were compared using a series of proteomic and bioactivity testing techniques to investigate and compare the toxin composition and functioning of the venoms of these two species...
May 11, 2018: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/29753251/long-term-exposure-to-ambient-particulate-matter-pm-2-5-is-associated-with-platelet-counts-in-adults
#11
Zilong Zhang, Ta-Chien Chan, Cui Guo, Ly-Yun Chang, Changqing Lin, Yuan Chieh Chuang, Wun Kai Jiang, Kin Fai Ho, Tony Tam, Kam S Woo, Alexis K H Lau, Xiang Qian Lao
BACKGROUND: The prothrombotic effects of particulate matter (PM) may underlie the association of air pollution with increased risks of cardiovascular disease. This study aimed to investigate the association between long-term exposure to PM with an aerodynamic diameter ≤2.5 μm (PM2.5 ) and platelet counts, a marker of coagulation profiles. METHODS: The study participants were from a cohort consisting of 362,396 Taiwanese adults who participated in a standard medical examination program between 2001 and 2014...
May 9, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29748615/specific-targeting-of-point-mutations-in-egfr-l858r-positive-lung-cancer-by-crispr-cas9
#12
Alvin Ho-Kwan Cheung, Chit Chow, Jinglin Zhang, Yuhang Zhou, Tingting Huang, Kayla Ching-Kei Ng, Terry Cho-Tsun Or, Yoyo Yao Yao, Yujuan Dong, Jackie Mei-Wah Fung, Lei Xiong, Aden Ka-Yin Chan, Wai-Ming Raymond Lung, Wei Kang, Ka-Fai To
Cancer cells are defined genetically by the mutations they harbor, commonly single nucleotide substitutions. Therapeutic approaches which specifically target cancer cells by recognizing these defining genetic aberrations are expected to exhibit minimal side-effects. However, current protein-based targeted therapy is greatly limited by the range of genes that can be targeted, as well as by acquired resistance. We hypothesized that a therapeutic oligonucleotide-based strategy may address this need of specific cancer targeting...
May 10, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/29746497/peritoneal-dialysis-related-peritonitis-caused-by-pseudomonas-species-insight-from-a-post-millennial-case-series
#13
Wanhong Lu, Bonnie Ching-Ha Kwan, Kai Ming Chow, Wing-Fai Pang, Chi Bon Leung, Philip Kam-To Li, Cheuk Chun Szeto
BACKGROUND: Pseudomonas peritonitis is a serious complication of peritoneal dialysis (PD). However, the clinical course of Pseudomonas peritonitis following the adoption of international guidelines remains unclear. METHODS: We reviewed the clinical course and treatment response of 153 consecutive episodes of PD peritonitis caused by Pseudomonas species from 2001 to 2015. RESULTS: Pseudomonas peritonitis accounted for 8.3% of all peritonitis episodes...
2018: PloS One
https://www.readbyqxmd.com/read/29744786/correction-to-raised-serum-il-8-levels-are-associated-with-excessive-fatigue-in-female-carriers-of-x-linked-chronic-granulomatous-disease-in-the-uk
#14
Alexandra C Battersby, Alexander J Martin, Jessica Tarn, W F Ng, Catherine M Cale, David Goldblatt, Andrew R Gennery
The original version of the article, "Raised Serum IL-8 Levels Are Associated with Excessive Fatigue in Female Carriers of X-Linked Chronic Granulomatous Disease in the UK" incorrectly listed the name of the fourth author as Fai W. Ng. The correct spelling of the author's name is WF Ng.
April 23, 2018: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/29740983/ch-3-nh-3-pbi-3-and-hc-nh-2-2-pbi-3-powders-synthesized-from-low-grade-pbi-2-single-precursor-for-high-efficiency-perovskite-solar-cells
#15
Yong Zhang, Seul-Gi Kim, Do-Kyoung Lee, Nam-Gyu Park
High-efficiency perovskite solar cells are generally fabricated by using highly pure (>99.99 %) PbI2 mixed with an organic iodide in polar aprotic solvents. However, the use of such an expensive chemical may impede progress toward large-scale industrial applications. Here, we report on the synthesis of perovskite powders by using inexpensive low-grade (99 %) PbI2 and on the photovoltaic performance of perovskite solar cells prepared from a powder-based single precursor. Pure APbI3 [A=methylammonium (MA) or formamidinium (FA)] perovskite powders were synthesized by treating low-grade PbI2 with MAI or FAI in acetonitrile at ambient temperature...
May 9, 2018: ChemSusChem
https://www.readbyqxmd.com/read/29739301/sub-elite-football-players-with-hip-related-groin-pain-and-positive-flexion-adduction-internal-rotation-test-exhibit-distinct-biomechanical-differences-compared-with-the-asymptomatic-side
#16
Matthew G King, Adam I Semciw, Harvi F Hart, Anthony G Schache, Kane J Middleton, Josh J Heerey, Rintje Agricola, Kay M Crossley
Study Design Observational cross-sectional study. Background Hip-related groin pain is common in sub-elite football players and may be associated with altered hip biomechanics. Objectives To compare the hip biomechanics, bony hip morphology associated with femoroacetabular impingement (FAI) syndrome, and hip strength and range of motion between the symptomatic and asymptomatic limb of sub-elite football players with unilateral hip-related groin pain and a positive flexion adduction internal rotation test. Methods Fifteen sub-elite football (soccer) players with unilateral hip-related groin pain and a positive flexion adduction internal rotation test were recruited...
May 8, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29736035/controlling-magnetism-in-2d-cri-3-by-electrostatic-doping
#17
Shengwei Jiang, Lizhong Li, Zefang Wang, Kin Fai Mak, Jie Shan
The atomic thickness of two-dimensional materials provides a unique opportunity to control their electrical 1 and optical 2 properties as well as to drive the electronic phase transitions 3 by electrostatic doping. The discovery of two-dimensional magnetic materials4-10 has opened up the prospect of the electrical control of magnetism and the realization of new functional devices 11 . A recent experiment based on the linear magneto-electric effect has demonstrated control of the magnetic order in bilayer CrI3 by electric fields 12 ...
May 7, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29734501/using-multidimensional-topological-data-analysis-to-identify-traits-of-hip-osteoarthritis
#18
Jasmine Rossi-deVries, Valentina Pedoia, Michael A Samaan, Adam R Ferguson, Richard B Souza, Sharmila Majumdar
BACKGROUND: Osteoarthritis (OA) is a multifaceted disease with many variables affecting diagnosis and progression. Topological data analysis (TDA) is a state-of-the-art big data analytics tool that can combine all variables into multidimensional space. TDA is used to simultaneously analyze imaging and gait analysis techniques. PURPOSE: To identify biochemical and biomechanical biomarkers able to classify different disease progression phenotypes in subjects with and without radiographic signs of hip OA...
May 7, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29733746/the-less-is-more-in-therapeutic-antibodies-afucosylated-anti-cancer-antibodies-with-enhanced-antibody-dependent-cellular-cytotoxicity
#19
Natasha A Pereira, Kah Fai Chan, Pao Chun Lin, Zhiwei Song
Therapeutic monoclonal antibodies are the fastest growing class of biological therapeutics for the treatment of various cancers and inflammatory disorders. In cancer immunotherapy, some IgG1 antibodies rely on the Fc-mediated immune effector function, antibody-dependent cellular cytotoxicity (ADCC), as the major mode of action to deplete tumor cells. It is well-known that this effector function is modulated by the N-linked glycosylation in the Fc region of the antibody. In particular, absence of core fucose on the Fc N-glycan has been shown to increase IgG1 Fc binding affinity to the FcγRIIIa present on immune effector cells such as natural killer cells and lead to enhanced ADCC activity...
May 7, 2018: MAbs
https://www.readbyqxmd.com/read/29733696/mri-assessment-of-supra-and-infratrochanteric-femoral-torsion-association-with-femoroacetabular-impingement-and-hip-dysplasia
#20
Benjamin Fritz, Susanne Bensler, Michael Leunig, Patrick O Zingg, Christian W A Pfirrmann, Reto Sutter
OBJECTIVE: The objective of our study was to evaluate a novel measurement technique for assessing the supra- and infratrochanteric components of femoral torsion, establish reference values in healthy volunteers, and compare supra- and infratrochanteric torsion angles in patients with hip dysplasia and patients with femoroacetabular impingement (FAI) with those in healthy volunteers. MATERIALS AND METHODS: Femoral torsion was assessed in 380 patients and 61 healthy volunteers on MRI...
May 7, 2018: AJR. American Journal of Roentgenology
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