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Umbilical artery Doppler

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https://www.readbyqxmd.com/read/29121743/profiling-of-cardiovascular-and-cerebrovascular-disease-associated-microrna-expression-in-umbilical-cord-blood-in-gestational-hypertension-preeclampsia-and-fetal-growth-restriction
#1
Ilona Hromadnikova, Katerina Kotlabova, Katarina Ivankova, Yulia Vedmetskaya, Ladislav Krofta
BACKGROUND AND METHODS: Gene expression of 29 cardiovascular and cerebrovascular disease associated microRNAs was assessed in whole umbilical cord blood, compared between groups [47 gestational hypertension (GH), 56 preeclampsia (PE), 37 fetal growth restriction (FGR) and 44 normal pregnancies] and correlated with the severity of the disease with respect to clinical signs (mild PE vs. severe PE), delivery date (before and after 34weeks of gestation), and Doppler ultrasound parameters [pulsatility index (PI) in the umbilical artery, PI in the middle cerebral artery and the cerebroplacental ratio]...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29112084/feed-related-splanchnic-oxygenation-in-preterm-infants-with-abnormal-antenatal-doppler-developing-gut-complications
#2
Silvia Martini, Arianna Aceti, Isadora Beghetti, Giacomo Faldella, Luigi Corvaglia
Preterm infants with antenatal absent or reversed end diastolic flow (AREDF) in umbilical arteries are at major risk for gastrointestinal (GI) complications, such as necrotizing enterocolitis, intestinal perforation and feeding intolerance. Near-infrared spectroscopy (NIRS) provides continuous monitoring of splanchnic oxygenation (SrSO2) and might represent a useful tool to predict GI outcomes in this high-risk population.This observational, pilot study assessed feed-related SrSO2 patterns at enteral feeding introduction and full enteral feeding (FEF) achievement in twenty AREDF infants with gestational age ≤34 weeks...
November 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29110317/fetal-growth-standards-in-gastroschisis-reference-values-for-ultrasound-measurements
#3
Mariane Massaini Barbieri, João Renato Bennini, Marcelo Luís Nomura, Sirlei Siani Morais, Fernanda Garanhani Surita
OBJECTIVES: To create growth curves based on ultrasonography biometric parameters of fetuses with gastroschisis, comparing them with normal growth standards and to analyze umbilical artery (AU) Doppler velocimetry patterns. METHODS: A cohort study of 72 fetuses with gastroschisis, at gestational ages between 14 and 39 weeks was designed. Mean and standard deviation were calculated, with the 5th, 10th, 50th, 90th and 95th centiles being established for biometric parameters according to gestational age...
November 7, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29105215/re-outcome-of-monochorionic-twin-pregnancy-with-selective-intrauterine-growth-restriction-according-to-umbilical-artery-doppler-flow-pattern-of-smaller-twin-systematic-review-and-meta-analysis-d-buca-g-pagani-g-rizzo-a-familiari-m-e-flacco-l-manzoli-m-liberati
#4
COMMENT
https://www.readbyqxmd.com/read/29061514/bold-mri-demonstrates-acute-placental-and-fetal-organ-hypoperfusion-with-fetal-brain-sparing-during-hypercapnia
#5
Yehuda Ginosar, Yuval Gielchinsky, Nathalie Nachmansson, Lital Hagai, Joel Shapiro, Uriel Elchalal, Rinat Abramovitch
INTRODUCTION: We evaluated changes in placental and fetal hemodynamics in rodents during acute hypercapnia using BOLD-MRI and Doppler ultrasound. METHODS: Animals were anesthetized with pentobarbital and, in consecutive 4-min periods, breathed: air, 21%O2:5%CO2, and 95%O2:5%CO2. BOLD-MRI: Pregnant ICR mice (n = 6; E17.5) were scanned in a 4.7-T Bruker Biospec spectrometer. Placenta and fetal liver, heart and brain were identified on True-FISP images...
September 11, 2017: Placenta
https://www.readbyqxmd.com/read/29037551/ductus-venosus-doppler-and-the-postnatal-outcomes-of-growth-restricted-fetuses-with-absent-end-diastolic-blood-flow-in-the-umbilical-arteries
#6
Nobuhiro Hidaka, Yuka Sato, Saki Kido, Yasuyuki Fujita, Kiyoko Kato
OBJECTIVE: We aimed to evaluate the outcomes of growth-restricted fetuses with absent end-diastolic velocity in the umbilical arteries (UA-AEDV), and investigate the relationship between Doppler flow velocity waveforms in the ductus venosus (DV) and the clinical features. MATERIALS AND METHODS: This was a retrospective study of growth-restricted fetuses diagnosed with UA-AEDV delivered at our institution between 2013 and 2015. The time from diagnosis of UA-AEDV to delivery, postnatal survival, and developmental prognoses were the primary outcomes...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29025195/chromosomal-and-subchromosomal-anomalies-associated-to-small-for-gestational-age-fetuses-with-no-additional-structural-anomalies
#7
Ruan Peng, Yi Zhou, Hong-Ning Xie, Mei-Fang Lin, Ju Zheng
OBJECTIVES: To assess the chromosomal and subchromosomal anomalies in small for gestational age (SGA) fetuses with no additional structural anomalies and their clinical outcomes. METHODS: This study retrospectively reviewed the 128 SGA fetuses with no additional anomalies and underwent genetic testing with karyotyping and chromosomal microarray analysis (CMA). Stratified analysis was performed according to the existence of maternal risk factors for SGA (yes or no), gestational age at onset (before or after 32 weeks), presence of oligohydraminos (yes or no) and umbilical artery (UA) Doppler flow (normal or abnormal)...
October 12, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29024133/plasma-natriuretic-peptide-levels-in-fetuses-with-congenital-heart-defect-and-arrhythmia-a-single-center-prospective-study
#8
Takekazu Miyoshi, Takashi Umekawa, Hiroshi Hosoda, Takashi Asada, Akihiro Fujiwara, Ken-Ichi Kurosaki, Isao Shiraishi, Michikazu Nakai, Kunihiro Nishimura, Mikiya Miyazato, Kenji Kangawa, Tomoaki Ikeda, Jun Yoshimatsu, Naoto Minamino
OBJECTIVES: Diagnosing fetal heart failure remains challenging because it is difficult to know how well the fetal myocardium will perform as loading conditions change. In adult cardiology, natriuretic peptides (NPs) are established marker of heart failure. However, the number of studies investigating NP levels in fetuses is quite limited. The aim of this study was to evaluate the significance of plasma NP levels in the assessment of heart failure in fetuses with congenital heart defect (CHD) and arrhythmia...
October 11, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29019748/doppler-us-in-the-evaluation-of-fetal-growth-and-perinatal-health
#9
Kristen R Uquillas, Brendan H Grubbs, Ashley E Prosper, Ramen H Chmait, Edward G Grant, Daphne K Walker
Fetal growth restriction is commonly defined as an estimated fetal weight (EFW) that is below the 10th percentile for gestational age. It is associated with an increased risk of intrauterine demise, neonatal morbidity, and neonatal death; therefore, antenatal detection and surveillance with the optimization of delivery timing are necessary to improve pregnancy outcomes. If the estimated due date has been verified and the EFW is below the 10th percentile for gestational age, the underlying cause should be investigated, since the clinical management, outcome, and counseling options are largely dependent on the cause of the growth restriction...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28966042/pregnancy-in-women-with-corrected-aortic-coarctation-uteroplacental-doppler-flow-and-pregnancy-outcome
#10
Anne S Siegmund, Marlies A M Kampman, Caterina M Bilardo, Ali Balci, Arie P J van Dijk, Martijn A Oudijk, Barbara J M Mulder, Jolien W Roos-Hesselink, Gertjan Tj Sieswerda, Steven V Koenen, Krystyna M Sollie-Szarynska, Tjark Ebels, Dirk J van Veldhuisen, Petronella G Pieper
OBJECTIVE: Women with repaired coarctation of the aorta (rCoA) are at risk of hypertensive disorders and other complications during pregnancy. Hypertensive disorders in pregnant women are associated with inadequate uteroplacental flow, which is related to adverse offspring outcome. The aim of this study was to investigate the relationship of maternal cardiac function, placental function and pregnancy complications in women with rCoA. METHODS: We included 49 pregnant women with rCoA and 69 controls from the prospective ZAHARA-studies (Zwangerschap bij Aangeboren HARtAfwijkingen, pregnancy in congenital heart disease)...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28960438/evaluating-a-targeted-bedside-measure-of-cerebral-perfusion-in-a-nonhuman-primate-model-of-neonatal-hypoxic-ischemic-encephalopathy
#11
Eric S Peeples, Chikodinaka K Ezeokeke, Sandra E Juul, Pierre D Mourad
OBJECTIVES: To compare ultrasound-derived resistive indices (RIs) obtained at the level of the thalamus via fast Doppler ultrasound with traditional anterior cerebral artery measures in a model of neonatal hypoxic-ischemic encephalopathy and to correlate each with clinical outcomes. METHODS: Nine nonhuman primate neonates underwent no umbilical cord occlusion (n = 3), umbilical cord occlusion without hypothermia (n = 3), or umbilical cord occlusion with hypothermia (n = 3)...
September 29, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28954334/-pregnancy-outcome-of-planning-pregnancies-in-patients-with-sle
#12
Z P Zhan, Y F Zhan, Y Yang, D Y Chen, L Q Liang, X Y Yang
Objectives: To investigate the pregnancy outcomes in systemic lupus erythematosus (SLE) patients with planning pregnancy.And to evaluate the value of fetal umbilical artery Doppler. Methods: A total of 130 SLE patients with planning pregnancy were prospectively recruited from January 2013 to January 2017 at the First Affiliated Hospital of Sun Yat-sen University. Results: Thirty eight (29.2%) patients had active lupus, 30 with mild activity, 5 with moderate activity and 3 with severe activity.Active disease in the first, second and third trimesters occurred in 6, 11 and 21 cases respectively...
September 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28926826/a-low-cerebroplacental-ratio-at-20-24-weeks-of-gestation-can-predict-reduced-fetal-size-later-in-pregnancy-or-at-birth
#13
Edgar Hernandez-Andrade, Eli Maymon, Offer Erez, Homam Saker, Suchaya Luewan, Maynor Garcia, Hyunyoung Ahn, Adi L Tarca, Bogdan Done, Steven J Korzeniewski, Sonia S Hassan, Roberto Romero
AIM: To determine whether Doppler evaluation at 20-24 weeks of gestation can predict reduced fetal size later in pregnancy or at birth. METHODS: Fetal biometry and Doppler velocimetry were performed in 2,986 women with a singleton pregnancy at 20-24 weeks of gestation. Predictive performances of the umbilical artery pulsatility index (UA-PI) or the mean uterine artery pulsatility index (UtA-PI) >95th percentile, middle cerebral artery pulsatility index, or cerebroplacental ratio (CPR) <5th percentile for early small for gestational age (SGA; <34 weeks of gestation), late SGA (≥34 weeks of gestation), or SGA at birth (birthweight <10th percentile) were analyzed...
September 20, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28892981/effect-of-transdermal-nitroglycerine-on-doppler-velocity-waveforms-of-the-uterine-umbilical-and-fetal-middle-cerebral-arteries-in-patients-with-chronic-placental-insufficiency-a-prospective-rct
#14
Suruchi Gupta, Meenakshi Chauhan, Jyotsna Sen, Smiti Nanda
INTRODUCTION: Increase in Nitric Oxide (NO) may be important in vascular adaptation needed to accommodate increased uteroplacental blood flow as pregnancy advances. Hence, in certain conditions like Pregnancy Induced Hypertension (PIH) and Fetal Growth Restriction (FGR), NO donors may play an effective role in increasing uteroplacental perfusion. Transdermal route appears to be a safe and effective route. AIM: To evaluate the effect of nitroglycerine patch on Doppler velocity waveforms of the uterine, umbilical and fetal middle cerebral arteries in patients with chronic placental insufficiency...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28859279/the-superovulated-environment-independent-of-embryo-vitrification-results-in-low-birthweight-in-a-mouse-model
#15
Rachel Weinerman, Teri Ord, Marisa S Bartolomei, Christos Coutifaris, Monica Mainigi
Epidemiological studies suggest that babies born following in vitro fertilization (IVF) and fresh embryo transfer are of lower birthweight than babies born following frozen embryo transfer, although the mechanism responsible for this phenotype is not known. We developed a novel mouse model that isolates the independent effects of embryo freezing and the superovulated environment, which cannot be performed in humans. We transferred blastocysts that had been vitrified and warmed, mixed with with fresh blastocysts, into individual pseudopregnant recipients produced by either natural mating or mating following injection with equine chorionic gonadotropin and human chorionic gonadotropin and hCG (superovulation)...
July 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28818013/relationship-between-doppler-findings-and-fetal-brain-apparent-diffusion-coefficient-in-early-onset-intra-uterine-growth-restriction
#16
Mehmet Serdar Kutuk, Murside Sahin, Sureyya Burcu Gorkem, Selim Doganay, Ahmet Ozturk
OBJECTIVE: The aim of the study is to assess the relationship between uteroplacental Doppler sonography findings and cerebral diffusion measured by diffusion-weighted magnetic resonance imaging (DWI) in fetuses with early-onset intrauterine growth restriction (IUGR). MATERIALS AND METHODS: The study included 54 pregnant women with fetal IUGR and 15 healthy controls (n: 15). Fetuses with IUGR were classified into four groups based on Doppler findings: group 1 (n = 12), umbilical artery (UA) pulsatility index (PI) > 95pc; group 2 (n = 11), UA PI >95 pc and middle cerebral artery PI < 5pc; group 3 (n = 21), absent end-diastolic (A-EDF) in UA; group 4 (n = 10), reversed EDF in UA...
September 4, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28790780/doppler-indices-of-the-umbilical-and-fetal-middle-cerebral-artery-at-18-40-weeks-of-normal-gestation-a-pilot-study
#17
Satyabrat Srikumar, Jyotindu Debnath, R Ravikumar, H C Bandhu, V K Maurya
BACKGROUND: Doppler indices form an integral component of noninvasive evaluation of fetal well-being. There is paucity of information about normal obstetric Doppler indices, particularly from the Indian subcontinent. The aim of the study was to find the values of pulsatility index (PI), resistive index (RI) of umbilical artery (UA), and fetal middle cerebral artery (MCA) and calculate cerebro-placental ratio (CP ratio) for 18-40 weeks of normal gestation so that a reference range of these Doppler values can be postulated...
July 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28782146/cerebroplacental-ratio-in-reduced-fetal-movements-evidence-for-worsening-fetal-hypoxemia
#18
Julia Binder, Caitriona Monaghan, Baskaran Thilaganathan, José Morales-Roselló, Asma Khalil
OBJECTIVE: To investigate the fetal cerebroplacental ratio (CPR) in women presenting with reduced fetal movements (RFM). METHODS: This is a retrospective cohort study conducted over a 7-year period at a Fetal Medicine Unit at a tertiary referral centre. 4500 singleton pregnancies presenting with RFM after 36 weeks' gestation and 1527 control pregnancies at a similar gestation without RFM were analysed. Fetal biometry and Doppler parameters were recorded and converted into centiles and multiples of the median (MoM)...
August 7, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28770306/prenatal-echocardiographic-predictors-of-postnatal-management-strategy-in-the-fetus-with-right-ventricle-hypoplasia-and-pulmonary-atresia-or-stenosis
#19
Li Cao, Zhiyun Tian, Jack Rychik
Fetuses with pulmonary atresia or pulmonary stenosis with intact ventricular septum manifest variable degrees of right ventricle hypoplasia and inadequacy. We studied the relationship between prenatal echocardiographic parameters and their progression through gestation as potential predictors of postnatal single-ventricle or two-ventricle care strategy. Serial fetal echocardiograms of pulmonary atresia (n = 28) or severe pulmonary stenosis (n = 8) and intact ventricular septum were reviewed. Measurements included tricuspid valve and mitral valve diameter and Z scores, degree of tricuspid regurgitation, presence of subaortic stenosis, presence of coronary artery fistulae, and Doppler pulsatility indices in middle cerebral and umbilical artery...
December 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28768058/prenatal-influence-of-congenital-heart-defects-on-trajectories-of-cortical-folding-of-the-fetal-brain-using-three-dimensional-ultrasound
#20
Irene V Koning, Anne W van Graafeiland, Irene A L Groenenberg, Sofie C Husen, Attie T J I Go, Jeroen Dudink, Sten P Willemsen, Jerome M J Cornette, Régine P M Steegers-Theunissen
OBJECTIVE: The objective of the study is to investigate the prenatal influence of congenital heart defects (CHD) on trajectories of fetal cortical folding using three-dimensional ultrasound (3D US). METHOD: We included 20 CHD fetuses and 193 controls for studying the fetal brain at 22, 26 and 32 weeks' gestational age (GA). The Sylvian, insula and parieto-occipital fissure (POF) depths were measured using 3D US, and reliability was evaluated. Doppler indices of the umbilical artery and middle cerebral artery were measured to calculate the cerebro-placental ratio...
October 2017: Prenatal Diagnosis
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