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https://www.readbyqxmd.com/read/29404645/-from-stiff-man-syndrome-to-stiff-person-spectrum-disorders
#1
H-M Meinck, B Balint
The identification of new variants of the stiff man syndrome (SMS) and of new, probably pathogenic neuronal autoantibodies has led to the concept of stiff man (or person) spectrum disorders (SPSD). This is an expanding group of rare chronic autoimmune inflammatory diseases of the central nervous system (CNS) that have in common the main symptoms of fluctuating rigidity and spasms with pronounced stimulus sensitivity. These core symptoms are mandatory and can be accompanied by a wide variety of other neurological signs...
February 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29380650/demystifying-balint-culture-and-its-impact-an-autoethnographic-analysis
#2
Jeffrey L Sternlieb
Balint groups are a structured group process designed for physicians and other helping professionals to provide feedback to each other concerning troublesome patient encounters. The process of Balint groups has survived and even thrived for more than a half century since their inception, suggesting their inherent value. However, measuring the impact in order to communicate the nature of that value has been elusive. A recent literature review highlighted the equivocal nature of research results and suggested that well-designed qualitative research may be more effective in selecting target measures which could result in better evidence for this group process...
January 2018: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29380649/characterizing-the-good-enough-balint-group-a-work-in-progress
#3
C Paul Scott, Laurel Milberg, Richard Addison
No abstract text is available yet for this article.
January 2018: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29361519/curcumin-and-derivatives-function-through-protein-phosphatase-2a-and-presenilin-orthologues-in-dictyostelium-discoideum
#4
Marco Cocorocchio, Amy J Baldwin, Balint Stewart, Lou Kim, Adrian J Harwood, Christopher R L Thompson, Paul L R Andrews, Robin S B Williams
Natural compounds often have complex molecular structures and unknown molecular targets. These characteristics make them difficult to analyse using a classical pharmacological approach. Curcumin, the main curcuminoid of turmeric, is a complex molecule possessing wide-ranging biological activities, cellular mechanisms and roles in potential therapeutic treatment including Alzheimer's disease and cancer. Here, we investigate the physiological effects and molecular targets of curcumin in Dictyostelium discoideum We show curcumin causes acute effects on cell behaviour, reduces cell growth, and slows multicellular development...
December 28, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/29356533/access-to-fluorazones-by-intramolecular-dehydrative-cyclization-of-aromatic-tertiary-amides-a-synthetic-and-mechanistic-study
#5
Béla Mátravölgyi, Tamás Hergert, Erika Bálint, Péter Bagi, Ferenc Faigl
An efficient synthesis has been developed for the preparation of 9H-pyrrolo[1,2-a]indol-9-ones (fluorazones) from readily available anthranilic acid derivatives via a one-pot amide- and pyrrole-formation step, followed by an intramolecular cyclodehydration. The cyclodehydration process is mediated by the activation of aromatic tertiary amides by triflic anhydride (Tf2O). Comparison of various benzo-substituents is shown in order to demonstrate the high functional group tolerance of this transformation. In addition, study of the reaction mechanism is also presented to unfold the exact role of the applied base additive...
January 22, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29342011/utility-of-time-and-frequency-domain-parameters-of-heart-rate-variability-in-the-context-of-autonomic-disorders-characterized-by-orthostatic-dysfunction
#6
Jacquie Baker, Juan M Racosta, Brittany Balint, Kurt Kimpinski
PURPOSE: The clinical significance of heart rate variability in the context of autonomic dysfunction continues to be a matter of debate. A consensus is lacking on the best heart rate variability measures for clinical purposes. Therefore, the purpose of this study was to investigate the utility of heart rate variability parameters in healthy versus autonomic dysfunction. METHODS: Healthy young (n = 134), healthy older (n = 32), and patients with mild (postural tachycardia syndrome; n = 25) and severe (neurogenic orthostatic hypotension; n = 34) autonomic dysfunction were included...
January 16, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29315873/dominance-of-free-wall-radial-motion-in-global-right-ventricular-function-of-heart-transplant-recipients
#7
Bálint Károly Lakatos, Márton Tokodi, Alexandra Assabiny, Zoltán Tősér, Annamária Kosztin, Alexandra Doronina, Kristóf Rácz, Kinga Bianka Koritsánszky, Viktor Berzsenyi, Endre Németh, Balázs Sax, Attila Kovács, Béla Merkely
Assessment of right ventricular (RV) function using conventional echocardiography might be inadequate as the radial motion of the RV free wall is often neglected. Our aim was to quantify the longitudinal and the radial components of RV function using three-dimensional (3D) echocardiography in heart transplant (HTX) recipients. 51 HTX patients in stable cardiovascular condition without history of relevant rejection episode or chronic allograft vasculopathy and 30 healthy volunteers were enrolled. RV end-diastolic (EDV) volume and total ejection fraction (TEF) were measured by 3D echocardiography...
January 8, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29308001/chronic-kidney-disease-severely-deteriorates-the-outcome-of-gastrointestinal-bleeding-a-meta-analysis
#8
Roland Hágendorn, Nelli Farkas, Áron Vincze, Zoltán Gyöngyi, Dezső Csupor, Judit Bajor, Bálint Erőss, Péter Csécsei, Andrea Vasas, Zsolt Szakács, László Szapáry, Péter Hegyi, Alexandra Mikó
AIM: To understand the influence of chronic kidney disease (CKD) on mortality, need for transfusion and rebleeding in gastrointestinal (GI) bleeding patients. METHODS: A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or end-stage renal disease (ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization (LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model...
December 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29235909/the-role-of-balint-group-training-in-the-professional-and-personal-development-of-family-medicine-residents
#9
Marty Player, John R Freedy, Vanessa Diaz, Clive Brock, Alexander Chessman, Carolyn Thiedke, Alan Johnson
This paper presents a study based on the participation of PGY2 and PGY3 family medicine residents in Balint seminars that occurred twice monthly for 24 months. Balint groups were cofacilitated by leader pairs experienced with the Balint method. Prior to residency graduation, 18 of 19 eligible resident physicians (94.5%) completed 30- to 60-min semistructured interviews conducted by a research assistant. Resident physicians were told that these individual interviews concerned "…how we teach communication in residency...
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29235409/engaging-indigenous-maori-and-inward-migrating-asian-professionals-into-a-pakeha-white-european-dominated-balint-community-in-new-zealand
#10
Timothy McMichael
This inquiry began with two questions: How can the established predominately Pakeha/Caucasian (White European) Balint community in New Zealand more successfully engage both indigenous populations of both Maori and Pacifica origin into Balint work? And what is the existing Balint community doing to address the lack of Asian members of the Balint community in New Zealand, at a time when Asian health professionals are being recruited into the health sector at an increasingly high rate in comparison to White European entrants to the profession? These questions, and their preliminary answers presented here, invite the reader to reflect on both the challenges and opportunities in reaching out to groups different from our own...
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29235408/balint-work-and-the-creation-of-medical-knowledge
#11
John Muench
Michael Balint's pioneering work in primary care was not simply the application of psychodynamic theory to the complex problems and relationships encountered by clinicians. Rather, Balint's work was part of a wider conversation in Western epistemology that had already begun to break down the enlightenment rationalist agenda. Since the time of Descartes, we sought to find certain truth through decontextualizing and abstracting problems, and through separation of the observer from the thing observed, with a focus on finding universal timeless laws that could be generalized...
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29235407/creation-of-a-curriculum-for-the-balint-group-leader-education-fellowship
#12
Laurel Milberg, Albert Lichtenstein
No abstract text is available yet for this article.
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29235405/mapping-the-balint-groups-to-the-accreditation-council-for-graduate-medical-education-family-medicine-competencies
#13
Albert Lichtenstein, Jumana Antoun, Chris Rule, Katherine Knowlton, Jeffrey Sternlieb
Introduction Balint group discussions provide learning opportunities for many of the competencies and milestones put forward by the Accreditation Council for Graduate Medical Education. The current literature is mixed concerning the effect of Balint groups on communication skills and professionalism. Aim To map the content of the Balint discussion to the competencies and milestones put forward by the Accreditation Council for Graduate Medical Education. METHODOLOGY: A group who were both experts in Balint and members of the clinical competency committee of residency programs rated narratives that summarized Balint group discussions...
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29226753/balint-under-the-microscope-what-really-happens-in-balint-groups
#14
John Salinsky
No abstract text is available yet for this article.
January 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29199580/what-is-ganoderma-lucidum-in-the-molecular-era
#15
Viktor Papp, Bálint Dima, Solomon P Wasser
The scientific name Ganoderma lucidum has long been used in the global medicinal mushroom market, and many publications have proven its pharmacological properties and chemical components. Although several Ganoderma species have been described worldwide as having morphology considerably similar to that of G. lucidum s. str., this binomial is still the most frequently used in pharmacological studies. However, the use of particularly divergent nomenclature has caused major difficulties in the evaluation of the results of pharmacological studies...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29179663/balint-group-leadership-conceptual-foundations-and-a-framework-for-leadership-development
#16
Andrew Elder
This article is based on a talk given at the International Balint Federation leadership congress in Warsaw (September 2016). It explores the conceptual foundations of Balint group leadership and starts by emphasizing the mutuality between psychoanalysts and medical practitioners working together. The parallel process between consulting room and group, and subsequently from group back to the consulting room, is delineated as the central construct in understanding the role of the leader. Having proposed a conceptual model for thinking about leadership interventions, the article discusses developments in some contemporary approaches to leadership: coleadership, the use of role play, psychodrama, pushback, and morale...
July 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29167035/promoting-empathy-among-medical-students-a-two-site-randomized-controlled-study
#17
Céline Buffel du Vaure, Cédric Lemogne, Lucie Bunge, Annie Catu-Pinault, Nicolas Hoertel, Christian Ghasarossian, Marie-Eve Vincens, Eric Galam, Philippe Jaury
OBJECTIVE: To assess the effects of Balint groups on empathy measured by the Consultation And Relational Empathy Measure (CARE) scale rated by standardized patients during objective structured clinical examination and self-rated Jefferson's School Empathy Scale - Medical Student (JSPE-MS©) among fourth-year medical students. METHODS: A two-site randomized controlled trial were planned, from October 2015 to December 2015 at Paris Diderot and Paris Descartes University, France...
December 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29153681/various-levels-of-circulating-exosomal-total-mirna-and-mir-210-hypoxamir-in-different-forms-of-pregnancy-hypertension
#18
Orsolya Biró, Bálint Alasztics, Attila Molvarec, József Joó, Bálint Nagy, János Rigó
INTRODUCTION: Hypertension is a common complication during pregnancy, affecting 10% of pregnant women worldwide. Several microRNA (miRNA) were shown to be involved in hypertensive disorders of pregnancy. In preeclampsia (PE), placental dysfunction causes the enhanced release of extracellular vesicle-derived miRNAs. The hypoxia-sensitive hsa-mir-210 is the most common PE-associated miRNA, but its exosomal profile has not been investigated. OBJECTIVES: Our aims were to measure exosomal total-miRNA concentration and to perform expression analysis of circulating exosomal hsa-miR-210 in women affected by chronic hypertension (CHT) gestational hypertension (GHT) or PE...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29134099/assessment-of-owner-directed-aggressive-behavioural-tendencies-of-dogs-in-situations-of-possession-and-manipulation
#19
Anna Bálint, Gabriella Rieger, Ádám Miklósi, Péter Pongrácz
Excessive aggression is a common behaviour problem in dogs that can have various destructive effects on the affected people and the implicated dog. Aggressive behaviour directed towards the owner or other family members is one of the most frequently occurring aggressive phenotypes. Here, we examine the reliability of a short questionnaire assessing aggressive behaviours by two, contextually different behavioural tests: 'take away bone' and 'roll over'. Based on dogs' behaviour in the tests, we sorted dogs (N = 93) in two groups for each test, namely a less and a more disobedient/resistant group...
October 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29130134/is-it-possible-to-improve-prognostic-value-of-nccn-ipi-in-patients-with-diffuse-large-b-cell-lymphoma-the-prognostic-significance-of-comorbidities
#20
Darko Antic, Jelena Jelicic, Goran Trajkovic, Milena Todorovic Balint, Jelena Bila, Olivera Markovic, Ivan Petkovic, Vesna Nikolic, Bosko Andjelic, Vladislava Djurasinovic, Aleksandra Sretenovic, Mihailo Smiljanic, Vojin Vukovic, Biljana Mihaljevic
The prognostic value of the International Prognostic Index (IPI) has been re-evaluated in the rituximab-treated diffuse large B cell lymphoma (DLBCL) patients. Accordingly, National Comprehensive Cancer Network-IPI (NCCN-IPI) has been introduced to estimate prognosis of DLBCL patients. However, comorbidities that frequently affect elderly DLBCL patients were not analyzed. The aim of this study was to evaluate the prognostic significance of comorbidities using Charlson Comorbidity Index (CCI) in 962 DLBCL patients...
February 2018: Annals of Hematology
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