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embryo IVF oocyte implantation

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https://www.readbyqxmd.com/read/29132734/role-of-vitamin-e-and-d3-supplementation-in-intra-cytoplasmic-sperm-injection-outcomes-of-women-with-polycystic-ovarian-syndrome-a-double-blinded-randomized-placebo-controlled-trial
#1
Farnaz Fatemi, Afsaneh Mohammadzadeh, Mohammad Reza Sadeghi, Mohammad Mehdi Akhondi, Shayan Mohammadmoradi, Koorosh Kamali, Nicknam Lackpour, Sheida Jouhari, Simin Zafadoust, Sara Mokhtar, Ladan Giahi
BACKGROUND & AIMS: Ovulation induction has been proven to impose oxidative stress during ICSI treatment cycle. Also, data indicates that PCOS women show higher oxidative markers. Available data are not convincing about which antioxidant supplements have the potential to overcome oxidative stress in PCOS subjects. The aim of this trial was to investigate the possible role of combined vitamin E and D supplementation in the ICSI outcomes (oocyte number and quality, embryo number and quality, pregnancy rate) of PCOS subjects...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29124461/improvement-of-pregnancy-outcome-by-extending-embryo-culture-in-ivf-et-during-clinical-application
#2
Xiaopeng Zhao, Binbin Ma, Shaokang Mo, Lu Ma, Fei Chang, Liyuan Zhang, Fang Xu, Ling Wang
PURPOSE: The purpose of this study is to investigate the application value of the extended embryo culture for 7-8 h in day 3 morning during IVF-ET process. METHODS: Embryos were retrospectively assessed during 08:00-09:00 on the morning of day 3 in the control group, and were assessed once again at 16:00 in the afternoon in the extended culture (EC) group. The embryos with good developmental potential were preferentially selected to transfer. The cumulative pregnancy outcomes were analyzed in one oocyte retrieval cycle...
November 9, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29078039/effectiveness-of-seminal-plasma-in-ivf-treatment-a-systematic-review-and-meta-analysis
#3
Gabriele Saccone, Attilio Di Spiezio Sardo, Andrea Ciardulli, Claudia Caissutti, Marialuigia Spinelli, Daniel Surbek, Michael von Wolff
BACKGROUND: In in vitro fertilization (IVF) techniques only 20 to 25% of the transferred embryos lead to a pregnancy OBJECTIVE: To evaluate the beneficial effects of SP or semen applied at the time of oocyte aspiration or embryo transfer SEARCH STRATEGY: Electronic databases were searched from their inception until August 2017. SELECTION CRITERIA: We included all randomized controlled trials (RCTs) evaluating the effects of SP or semen in IVF treatment. Trials were considered if women were exposed to any kind of SP or semen (either SP/semen injection or sexual intercourse) around the time of oocyte pickup and embryo transfer...
October 27, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29037105/the-role-of-female-obesity-on-in-vitro-fertilization-outcomes
#4
Miro Kasum, Slavko Orešković, Ermin Čehić, Albert Lila, Emina Ejubović, Dragan Soldo
The aim of this review is to analyze the role of obesity on fertility outcome in women undergoing in vitro fertilization (IVF) with respect to clinical or live birth rates and pregnancy loss rates. Despite findings from several earlier and newer studies that obesity does not adversely affect pregnancy outcome in women attempting conception, numerous reports from mostly recent studies suggest that obesity undoubtedly impairs IVF outcomes. Obesity impairs ovarian responsiveness to gonadotrophin stimulation, requiring higher doses of medication, increased risk of cycle cancelation, pre-term delivery, low birth weight or miscarriage, and decreases implantation, clinical pregnancy or live birth rates compared to women of normal weight...
October 16, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28993105/dual-trigger-of-final-oocyte-maturation-in-poor-ovarian-responders-undergoing-ivf-icsi-cycles
#5
Jie Zhang, Yun Wang, Xiaoyan Mao, Qiuju Chen, Qingqing Hong, Renfei Cai, Shaozhen Zhang, Yanping Kuang
Previous studies show that a dual trigger ovulation regimen significantly improves number and maturity of retrieved oocytes for normal ovarian responders or patients with history of low oocyte yield. The current retrospective cohort study investigated whether dual trigger of final oocyte maturation may benefit IVF outcomes for poor ovarian responders fulfilling the Bologna criteria. Undertaken between May 2014 and August 2016, the study involved 1350 patients undergoing 1389 IVF/intracytoplasmic sperm injection treatment cycles...
September 21, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28985908/effect-of-the-male-factor-on-the-clinical-outcome-of-intracytoplasmic-sperm-injection-combined-with-preimplantation-aneuploidy-testing-observational-longitudinal-cohort-study-of-1-219-consecutive-cycles
#6
Rossella Mazzilli, Danilo Cimadomo, Alberto Vaiarelli, Antonio Capalbo, Lisa Dovere, Erminia Alviggi, Ludovica Dusi, Carlo Foresta, Francesco Lombardo, Andrea Lenzi, Herman Tournaye, Carlo Alviggi, Laura Rienzi, Filippo Maria Ubaldi
OBJECTIVE: To evaluate the impact of the male factor on the outcomes of intracytoplasmic sperm injection (ICSI) cycles combined with preimplantation genetic testing for aneuploidies (PGT-A). DESIGN: Observational longitudinal cohort study. SETTING: Private in vitro fertilization (IVF) center. PATIENT(S): A total of 1,219 oocyte retrievals divided into five study groups according to sperm parameters: normozoospermia (N), moderate male factor (MMF), severe oligoasthenoteratozoospermia (OAT-S), obstructive azoospermia (OA), and nonobstructive azoospermia (NOA)...
October 3, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28960429/the-effects-of-low-dose-human-chorionic-gonadotropin-combined-with-human-menopausal-gonadotropin-protocol-on-women-with-hypogonadotropic-hypogonadism-undergoing-ovarian-stimulation-for-in-vitro-fertilization
#7
Shutian Jiang, Yanping Kuang
OBJECTIVES: To investigate the effects of low-dose human chorionic gonadotropin (hCG) combined with human menopausal gonadotropin (HMG) protocol on cycle characteristics and outcomes of infertile women with hypogonadotropic hypogonadism (HH) undergoing ovarian stimulation for in vitro fertilization (IVF). DESIGN: A retrospective cohort study. SETTING: Tertiary-care academic medical centre. PATIENT(S): Forty-six infertile patients with HH and seventy-one infertile patients with tubal factor (TF) infertility undergoing IVF...
September 27, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28955073/comparison-of-embryo-morphokinetics-following-intracytoplasmic-sperm-injection-in-smoker-and-non-smoker-couples-are-the-results-different
#8
Ahmet Salvarci, Ali Sami Gurbuz, Sukru Uzman, Melek Kaya, Huseyin Gorkemli
OBJECTIVE: To assess early embryo development via time-lapse in smokers and non-smokers. METHODS: The retrospective study was conducted at Novafertil IVF centers in Konya, Turkey and comprised oocytes of both smoker and non-smoker couples subjected to in vitro fertilisation / introcytoplasmic sperm injection from 2012 to 2015. Age, basal follicle-stimulating hormone, number of stimulation days, amount of gonadotropin used, number of metaphase II oocytes, number of embryos transferred and pregnancy, abortus and clinical pregnancy rates were noted...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28931865/use-of-medroxyprogesterone-acetate-in-women-with-ovarian-endometriosis-undergoing-controlled-ovarian-hyperstimulation-for-in-vitro-fertilization
#9
Haiyan Guo, Yun Wang, Qiuju Chen, Weiran Chai, Lihua Sun, Ai Ai, Yonglun Fu, Qifeng Lyu, Yanping Kuang
This study investigated the use of medroxyprogesterone acetate (MPA) or a short protocol for controlled ovarian hyperstimulation (COH) in patients with advanced endometriosis who have normal ovarian function, and to compare cycle characteristics and pregnancy outcomes after frozen-thawed embryo transfer (FET). This was a retrospective case-control study of 244 patients with advanced endometriosis undering COH. The patients were allocated to three groups: the surgery group with MPA COH (62 patients, 71 IVF/ICSI cycles, 78 FET cycles); the aspiration group with MPA COH (85 patients had ovarian "chocolate" cysts (>3 cm) aspirated, 90 IVF/ICSI cycles, 76 FET cycles); and the short protocol group (97 patients, 101 IVF/ICSI cycles, 51 FET cycles)...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28915981/transcutaneous-electrical-acupoint-stimulation-improves-the-outcomes-of-in-vitro-fertilization-a-prospective-randomized-and-controlled-study
#10
Fan Qu, Fang-Fang Wang, Yan Wu, Jue Zhou, Nicola Robinson, Paul J Hardiman, Jie-Xue Pan, Yi-Jing He, Yu-Hang Zhu, Han-Zhi Wang, Xiao-Qun Ye, Ke-Lin He, Long Cui, Hong-Li Zhao, Ying-Hui Ye
OBJECTIVES: To explore whether transcutaneous electrical acupoint stimulation (TEAS) can improve the outcomes of in vitro fertilization (IVF). DESIGN: A prospective, randomized, and controlled study. SETTING: IVF center in a university hospital. PARTICIPANTS: Four hundred and eighty-one infertile patients with bilateral tubal blockage who were referred for IVF. Patients were randomized into four groups. INTERVENTION: TEAS was administered for 30min, respectively, at 24h before TVOR and two hours before ET...
September 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/28904494/vitamin-d-deficiency-does-not-influence-reproductive-outcomes-of-ivf-icsi-a-study-of-oocyte-donors-and-recipients
#11
Manish Banker, Dipesh Sorathiya, Sandeep Shah
BACKGROUND: Vitamin D and its active metabolite, 1,25-dihydroxy vitamin D (1,25-(OH)2D3), play a significant role in reproduction. AIM: To assess the effect of serum 25-hydroxy vitamin D level on oocyte quality and endometrial receptivity by studying oocyte donors and their recipients. MATERIALS AND METHODS: This prospective study consisted of two groups: Group A (recipient group) and Group B (donor group). All the participants of Groups A1 and B1 as well as Groups A2 and B2 were subcategorized into vitamin D-deficient (<20 ng/mL) and vitamin D replete-insufficient (20 to ≥30 ng/mL), respectively...
April 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28900763/the-association-between-fatty-acid-index-and-in-vitro-fertilization-outcomes
#12
Ashley M Eskew, Kelly C Wormer, Michelle L Matthews, H James Norton, Margaret A Papadakis, Bradley S Hurst
PURPOSE: Fatty acids have been shown to play an important role in oocyte competence and early implantation of the embryo. Our hypothesis-generating study sought to determine if individual fatty acids expressed as a percentage of total erythrocyte fatty acids are associated with embryo quality and other in vitro fertilization (IVF) outcomes. METHODS: This was a prospective cohort study at an academic fertility center. Sixty women undergoing their first IVF cycle were recruited...
September 13, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28895679/a-modern-approach-to-the-management-of-patients-candidate-to-assisted-reproductive-technologies
#13
Roberta Venturella, Alberto Vaiarelli, Daniela Lico, Filippo M Ubaldi, Fulvio Zullo, Costantino DI Carlo
The growing use of Assisted Reproductive Technologies (ART) and the incorrect information from mass media, determined in the public the wrong idea that the right moment of life for programming a pregnancy can be delayed well beyond the physiological fertile age. Spare and insufficient health authorities' interventions are driven to explain to the general population the reduction of the fertility potential of couples and particularly of women with advancing age. This situation, characterized by more and more women seeking for pregnancy after age 38-40 imposes to specialists in Reproductive Medicine an honest and transparent counselling...
September 12, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28886319/morphokinetic-analysis-of-human-embryo-development-and-its-relationship-to-the-female-age-a-retrospective-time-lapse-imaging-study
#14
N Akhter, M Shahab
Time-lapse imaging technique has provided embryologists with a unique chance of studying the embryo morphokineticsto select the most viable embryos for implantation in the field of IVF (In vitro fertilization).The conventional method of morphological evaluations has proved that maternal age affects the human embryo quality. This retrospective study carried out at Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan mainly focuses on the effect of female age on human embryo morphokinetics. A total number of 200 patients undergoing ICSI treatment cycles at the clinic were selected for the study and divided into five age groups (< 26, 26-30, 31-35, 36-40, and > 40 years)...
August 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28865549/effect-of-oocyte-vitrification-on-embryo-quality-time-lapse-analysis-and-morphokinetic-evaluation
#15
Ana Cobo, Aila Coello, Jose Remohí, Jose Serrano, Jose Maria de Los Santos, Marcos Meseguer
OBJECTIVE: To analyze whether oocyte vitrification may affect subsequent embryo development from a morphokinetic standpoint by means of time-lapse imaging. DESIGN: Observational cohort study. SETTING: University-affiliated private IVF center. PATIENT(S): Ovum donation cycles conducted with the use of vitrified (n = 631 cycles; n = 3,794 embryos) or fresh oocytes (n = 1,359 cycles; n = 9,935 embryos) over 2 years. INTERVENTIONS(S): None...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28854728/a-second-dose-of-kisspeptin-54-improves-oocyte-maturation-in-women-at-high-risk-of-ovarian-hyperstimulation-syndrome-a-phase-2-randomized-controlled-trial
#16
Ali Abbara, Sophie Clarke, Rumana Islam, Julia K Prague, Alexander N Comninos, Shakunthala Narayanaswamy, Deborah Papadopoulou, Rachel Roberts, Chioma Izzi-Engbeaya, Risheka Ratnasabapathy, Alexander Nesbitt, Sunitha Vimalesvaran, Rehan Salim, Stuart A Lavery, Stephen R Bloom, Les Huson, Geoffrey H Trew, Waljit S Dhillo
STUDY QUESTION: Can increasing the duration of LH-exposure with a second dose of kisspeptin-54 improve oocyte maturation in women at high risk of ovarian hyperstimulation syndrome (OHSS)? SUMMARY ANSWER: A second dose of kisspeptin-54 at 10 h following the first improves oocyte yield in women at high risk of OHSS. WHAT IS KNOWN ALREADY: Kisspeptin acts at the hypothalamus to stimulate the release of an endogenous pool of GnRH from the hypothalamus...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28835940/pregnancy-outcome-of-delayed-start-gnrh-antagonist-protocol-versus-gnrh-antagonist-protocol-in-poor-responders-a-clinical-trial-study
#17
Abbas Aflatoonian, Aflatoonian Hosseinisadat, Ramesh Baradaran, Maryam Farid Mojtahedi
BACKGROUND: Management of poor-responding patients is still major challenge in assisted reproductive techniques (ART). Delayed-start GnRH antagonist protocol is recommended to these patients, but little is known in this regards. OBJECTIVE: The goal of this study was assessment of delayed-start GnRH antagonist protocol in poor responders, and in vitro fertilization (IVF) outcomes. MATERIALS AND METHODS: This randomized clinical trial included sixty infertile women with Bologna criteria for ovarian poor responders who were candidate for IVF...
April 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28822715/reproductive-outcomes-of-segmented-in-vitro-fertilization-in-patients-diagnosed-with-endometriomas
#18
Kemal Ozgur, Hasan Bulut, Murat Berkkanoglu, Kevin Coetzee
STUDY OBJECTIVE: To assess the impact of ovarian endometriomas on endometrial receptivity in frozen embryo transfer (FET) of segmented in vitro fertilization (IVF) cycles. DESIGN: Retrospective, matched-control study (Canadian Task Force classification II-2). SETTING: A single, private assisted-reproduction technology center. PATIENTS: Thirty patients diagnosed with unilateral or bilateral endometriomas were compared with 60 patients without endometriomas in a population of 1894 patients who underwent segmented IVF treatment between September 2014 and September 2016...
August 16, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28810691/improvement-of-implantation-potential-in-mouse-blastocysts-derived-from-ivf-by-combined-treatment-with-prolactin-epidermal-growth-factor-and-4-hydroxyestradiol
#19
Miki Takeuchi, Misato Seki, Etsuko Furukawa, Akihito Takahashi, Kyosuke Saito, Mitsuru Kobayashi, Kenji Ezoe, Emiko Fukui, Midori Yoshizawa, Hiromichi Matsumoto
STUDY QUESTION: Can supplementation of medium with prolactin (PRL), epidermal growth factor (EGF) and 4-hydroxyestradiol (4-OH-E2) prior to embryo transfer improve implantation potential in mouse blastocysts derived from IVF? SUMMARY ANSWER: Combined treatment with PRL, EGF and 4-OH-E2 improves mouse blastocyst implantation rates, while alone, each factor is ineffective. WHAT IS KNOWN ALREADY: Blastocyst dormancy during delayed implantation caused by ovariectomy is maintained by continued progesterone treatment in mice, and estrogen injection rapidly activates blastocysts to implantation-induced status in vivo...
August 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28795047/influence-of-the-insemination-method-on-the-outcomes-of-elective-blastocyst-culture
#20
Caizhu Wang, Guixue Feng, Bo Zhang, Jinhui Shu, Hong Zhou, Xianyou Gan, Ruoyun Lin
OBJECTIVE: The aim of this study was to explore the effects of the insemination method on the outcomes of elective blastocyst culture. METHODS: We retrospectively analyzed the outcomes of elective blastocyst culture performed between January 2011 and December 2014. RESULTS: There were 2,003 cycles of conventional in vitro fertilization (IVF) and 336 cycles of intracytoplasmic sperm injection (ICSI), including 25,652 and 4,164 embryos that underwent sequential blastocyst culture, respectively...
June 2017: Clinical and Experimental Reproductive Medicine
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