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https://www.readbyqxmd.com/read/27753975/os-12-02-sleep-apnea-cardiovascular-endpoints-save-study-an-international-randomised-controlled-trial-to-determine-whether-continuous-positive-airways-pressure-treatment-for-obstructive-sleep-apnea-in-patients-with-cv-disease-prevents-secondary-cardiovascular
#1
Craig Anderson, Doug McEvoy, Jiguang Wang
OBJECTIVE: There is uncertainty over whether treatment of obstructive sleep apnea (OSA) can prevent serious cardiovascular (CV) events. DESIGN AND METHOD: SAVE (NCT00738179; ACTRN12608000409370) was designed to determine whether treatment of OSA with CPAP reduces the risk of serious CV events in patients with established CV disease. Participants were centrally randomised to CPAP treatment or usual care between 2008 and 2013,with follow-up completed late 2015 and the results will be announced in August 2016...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27735987/age-related-test-retest-reliability-of-isometric-trunk-torque-measurements-in-patiens-with-chronic-low-back-pain
#2
Thomas Kienbacher, Josef Kollmitzer, Phillipp Anders, Richard Habenicht, Christian Starek, Markus Wolf, Birgit Paul, Patrick Mair, Gerold Ebenbichler
OBJECTIVE: To investigate the short- and long-term reliability of isometric trunk strength measurements in patients with chronic low back pain in different age groups. DESIGN: Test-retest reliability study. PATIENTS: A total of 210 patients (age groups 18-39, 40-59 and 60-90 years). METHODS: Patients performed testing at baseline, 1-2 days (day 2) and 6 weeks. RESULTS: Only the oldest age group showed similar extension strength on all three test days All age groups showed significant changes in rotation and flexion scores from baseline to 6 weeks...
November 11, 2016: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27643372/os-12-02-sleep-apnea-cardiovascular-endpoints-save-study-an-international-randomised-controlled-trial-to-determine-whether-continuous-positive-airways-pressure-treatment-for-obstructive-sleep-apnea-in-patients-with-cv-disease-prevents-secondary-cardiovascular
#3
Craig Anderson, Doug McEvoy, Jiguang Wang
OBJECTIVE: There is uncertainty over whether treatment of obstructive sleep apnea (OSA) can prevent serious cardiovascular (CV) events. DESIGN AND METHOD: SAVE (NCT00738179; ACTRN12608000409370) was designed to determine whether treatment of OSA with CPAP reduces the risk of serious CV events in patients with established CV disease. Participants were centrally randomised to CPAP treatment or usual care between 2008 and 2013,with follow-up completed late 2015 and the results will be announced in August 2016...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27314861/defining-the-optimal-sequence-for-the-systemic-treatment-of-metastatic-breast-cancer
#4
J A Mestres, A B iMolins, L C Martínez, J I C López-Muñiz, E C Gil, A de Juan Ferré, S Del Barco Berrón, Y F Pérez, J G Mata, A G Palomo, J G Gregori, P G Pardo, J J I Mañas, A L Hernández, E M de Dueñas, N M Jáñez, S M Murillo, J S Bofill, P Z Auñón, P Sanchez-Rovira
Metastatic breast cancer is a heterogeneous disease that presents in varying forms, and a growing number of therapeutic options makes it difficult to determine the best choice in each particular situation. When selecting a systemic treatment, it is important to consider the medication administered in the previous stages, such as acquired resistance, type of progression, time to relapse, tumor aggressiveness, age, comorbidities, pre- and post-menopausal status, and patient preferences. Moreover, tumor genomic signatures can identify different subtypes, which can be used to create patient profiles and design specific therapies...
June 17, 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/26554810/nurses-own-recordkeeping-the-nursing-minimum-data-set-revisited
#5
Edward J Halloran, Diane C Halloran
There is no consistent, standardized, concise method for nurses to record information about their patients and clients that is conducive to store, retrieve, and use in patient and client care; to improve professional self-development; and to use in collaboration with patients and clients, their families, other nurses, doctors, hospitals, and health systems. Nurses gauge the health status of their patients and clients every day and are now in a position both to record their impressions for their own use and to share them with colleagues who care for the same patients and clients...
November 2015: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/26314449/-correlation-of-plasma-co-stimulatory-molecules-b7-h2-and-b7-h3-with-platelet-auto-antibodies-in-patients-with-immune-thrombocytopenic-purpura
#6
Bin Zuo, Yun-Xiao Zhao, Jian-Feng Yang, Yang He
OBJECTIVE: To investigate whether the plasma level of platelet auto- antibodies in ITP patients is related to that of co-stimulatory molecules sB7-H2 and sB7-H3. METHODS: A total of 61 ITP patients and 25 healthy controls from the First Affiliated Hospital of Soochow University from June 2012 to August 2013 were enrolled in this study. The expression levels of platelet auto-antibodies against 5 glycoproteins (GPIX, GP Ib, GP IIIa, GPIIb and P-selectin) in plasma were detected by flow cytometric immuno-beads array, and the expression of soluable co-stimulatory molecules sB7-H2 and sB7-H3 was measured by ELISA...
August 2015: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/26265411/-persistence-in-the-treatment-of-overactive-bladder-oab-with-mirabegron-in-a%C3%A2-multicentre-clinical-study
#7
MULTICENTER STUDY
A Martan, J Mašata, K Švabík, T Hanuš, J Krhut
OBJECTIVE: The objective of this monitoring was to evaluate persistence in the treatment of patients with overactive bladder syndrome (OAB) using mirabegron. DESIGN: Prospective clinical study. SETTING: 10 gynecological and urological departments in CZE. MATERIALS AND METHODS: This is an analysis of a prospective, multicenter monitoring which started in May 2014 and will continue for 1 year. This monitoring included patients 18 years old who have had symptoms of OAB for minimum 3 months...
August 2015: Ceská Gynekologie
https://www.readbyqxmd.com/read/26111283/-first-episode-psychosis-relationship-of-symptoms-initial-treatment-and-clinical-response
#8
Eren Yıldızhan, Ahmet Türkcan, Sibel İnan, Zehra Erenkuş, Özhan Yalçın, Ayten Erdoğan
OBJECTIVE: It was aimed to explore the relationship of clinical psychopathology and treatment response with "duration of untreated psychosis" (DUP) and "duration of untreated illness"(DUI) in 15-20 years old (mean age: 17,34 ± 1.69) inpatients in Turkey. METHOD: Mood disorders with psyhotic features were grouped as affective psychoses (18 patients, mean age: 17,28 ± 1,75); schizophrenia, schiozophreniform disorder and other psychotic disorders were grouped as non-affective psychoses (25 patients, mean age: 17,38 ± 1,68)...
2015: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/25849053/a-new-approach-in-the-diagnosis-of-upper-airway-resistance-syndrome-uars-pap-method
#9
Oğuz Köktürk, Ayşe Baha, Asiye Kanbay
INTRODUCTION: Upper airway resistance syndrome (UARS) is characterized by repeated number of arousals at night, and excessive daytime sleepiness or somnolence (EDS). It is often missed in classical polysomnographic diagnostic approaches and misdiagnosed as simple snoring or idiopathic hypersomnia, thereby is often left untreated. We propose that positive airway pressure (PAP), which has shown to be effective against UARS, can be used as a diagnostic tool as well. The study designed to test whether patients with high titration pressures can be diagnosed for UARS, and whether this pressure can be used as the treatment pressure in UARS...
2015: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/25723082/-urinary-incontinence-induced-by-the-antidepressants-case-report
#10
J Krhut, M Gärtner
AIM: Case study of the patient with urinary incontinence induced by the antidepressant mirtazapin and the review of the related literature. DESIGN: Case Report. SETTING: Department of Urology, University Hospital Ostrava-Poruba. CASE REPORT: A case of 55-years old patiens, who was reffered to the surgical treatment of the urinary incontinence. We found a major discrepancies during the evaluation that led us to suspect that this is not a common uncomplicated case of stress urinary incontinence...
January 2015: Ceská Gynekologie
https://www.readbyqxmd.com/read/24109522/postmastectomy-radiation-therapy-an-overview-for-the-practicing-surgeon
#11
REVIEW
Reshma Jagsi
Locoregional control of breast cancer is the shared domain and responsibility of surgeons and radiation oncologists. Because surgeons are often the first providers to discuss locoregional control and recurrence risks with patients and because they serve in a key gatekeeping role as referring providers for radiation therapy, a sophisticated understanding of the evidence regarding radiotherapy in breast cancer management is essential for the practicing surgeon. This paper synthesizes the complex and evolving evidence regarding the role of radiation therapy after mastectomy...
2013: ISRN Surgery
https://www.readbyqxmd.com/read/23771579/the-prognosis-of-self-reported-paresthesia-and-weakness-in-disc-related-sciatica
#12
L Grøvle, A J Haugen, B Natvig, J I Brox, M Grotle
PURPOSE: To explore how patients with sciatica rate the 'bothersomeness' of paresthesia (tingling and numbness) and weakness as compared with leg pain during 2 years of follow-up. METHODS: Observational cohort study including 380 patients with sciatica and lumbar disc herniation referred to secondary care. Using the Sciatica Bothersomeness Index paresthesia, weakness and leg pain were rated on a scale from 0 to 6. A symptom score of 4-6 was defined as bothersome...
November 2013: European Spine Journal
https://www.readbyqxmd.com/read/23713960/sutureless-aortic-valve-replacement-using-perceval-s-valve
#13
Shahzad G Raja
Surgical aortic valve replacement is the treatment of choice in patients with severe symptomatic aortic valve stenosis because it provides excellent early and long-term clinical outcomes in terms of hemodynamics, valve durability, and freedom from valve-related complications. In recent years, the number of high-risk patients being referred for surgical aortic valve replacement has increased. A considerable proportion of these patients are deemed operable despite the high risk. In order to modify the risk predominantly associated with duration of cardiopulmonary bypass and cross clamp time sutureless aortic valve technology has been developed...
August 2013: Recent Patents on Cardiovascular Drug Discovery
https://www.readbyqxmd.com/read/23700573/the-role-of-diverting-stoma-after-an-ultra-low-anterior-resection-for-rectal-cancer
#14
Seok In Seo, Chang Sik Yu, Gwon Sik Kim, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Jin Cheon Kim
PURPOSE: A diverting stoma is known to reduce the consequences of distal anastomotic failure following colorectal surgery. The aim of this study was to evaluate the efficacy of a diverting stoma after an ultra-low anterior resection (uLAR) for rectal cancer. METHODS: Between 2000 and 2007, 836 patients who underwent an uLAR were divided into two groups, depending on the fecal diversion: 246 received fecal diversion, and 590 had no diversion. Patient- and disease-related variables were compared between the two groups...
April 2013: Annals of Coloproctology
https://www.readbyqxmd.com/read/23682907/measuring-the-impacts-of-seclusion-on-psychiatry-inpatients-and-the-effectiveness-of-a-pilot-single-session-post-seclusion-counselling-intervention
#15
Fiona Whitecross, Amy Seeary, Stuart Lee
Despite the accumulation of evidence demonstrating patients' accounts of trauma associated with seclusion, the use of evidence-based post-seclusion debriefing is not apparent in the published work. This study aimed to identify the impacts seclusion has on an individual using the Impact of Events - Revised (IES-R), a standardized and widely used measure of trauma symptoms, and measure the effectiveness of a post-seclusion counselling intervention in mitigating the experience of seclusion-related trauma and reducing time spent in seclusion...
December 2013: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/23680756/hormones-and-dry-eye-syndrome-an-update-on-what-we-do-and-don-t-know
#16
REVIEW
Eduardo Melani Rocha, Flavio Mantelli, Luis Fernando Nominato, Stefano Bonini
PURPOSE OF REVIEW: Dry eye syndrome (DES) prevalence is large and its relationship with hormonal diseases is becoming clearer, although more complex. This review provides insight to this association as well as clarifying what remains unanswered about how to interpret and treat findings common to both DES and hormonal diseases. RECENT FINDINGS: Several sex hormone-related diseases are associated with DES. Hormone replacement therapy to correct such conditions has conflicting outcomes based on epidemiologic studies and clinical trials...
July 2013: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/23650670/-physician-patient-with-aids-relationship-as-a-model-of-clinical-relation-within-the-framework-of-the-social-security-institutions-in-mexico
#17
MULTICENTER STUDY
Edith Valdez-Martínez, Miguel Bedolla, Rosalía Rico
OBJECTIVE: To examine the nature and level of physician involvement during a clinical encounter with a patient with a chronic condition, such as AIDS, and to explore how it is understood and constructed by them. MATERIAL AND METHODS: Qualitative design with participant observation and semi-structured interviews, with physicians and patients, conducted in hospitals of Social Security Institutions in Mexico City Data were analyzed using the constant comparative method developed in the grounded theory tradition...
November 2011: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/23566123/navigating-the-legal-and-ethical-foundations-of-informed-consent-and-confidentiality-in-integrated-primary-care
#18
REVIEW
Cathy Hudgins, Sandra Rose, Peter Y Fifield, Steve Arnault
This article describes findings from ongoing research and analysis of current literature in addition to discussions with leaders in the field, communications with lawyers and administrators of advocacy and government agencies pertaining to integrated primary care (IPC). Standards of care are established based on a myriad of factors, including professional codes of ethics, case law, state and federal laws, professional standards, existing best practices, current professional guidelines, administrative rules and regulations, and licensing board regulations...
March 2013: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/23565902/migraine-predicts-physical-and-pain-symptoms-among-psychiatric-outpatients
#19
Ching-I Hung, Chia-Yih Liu, Shuu-Jiun Wang
BACKGROUND: No study has been performed to compare the impacts of migraine and major depressive episode (MDE) on depression, anxiety and somatic symptoms, and health-related quality of life (HRQoL) among psychiatric outpatients. The aim of this study was to investigate the above issue. METHODS: This study enrolled consecutive psychiatric outpatients with mood and/or anxiety disorders who undertook a first visit to a medical center. Migraine was diagnosed according to the International Classification of Headache Disorders, 2nd edition...
2013: Journal of Headache and Pain
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