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Meniscus repair

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https://www.readbyqxmd.com/read/28060534/is-it-necessary-to-repair-stable-ramp-lesions-of-the-medial-meniscus-during-anterior-cruciate-ligament-reconstruction
#1
Xin Liu, Hui Zhang, Hua Feng, Lei Hong, Xue-Song Wang, Guan-Yang Song
BACKGROUND: A special type of meniscal lesion involving the peripheral attachment of the posterior horn of the medial meniscus (PHMM), termed a "ramp lesion," is commonly associated with an anterior cruciate ligament (ACL) injury. However, its treatment is still controversial. Recently, stable ramp lesions treated with abrasion and trephination alone have been shown to have good clinical outcomes after ACL reconstruction. HYPOTHESIS: Stable ramp lesions treated with abrasion and trephination alone during ACL reconstruction will result in similar clinical outcomes compared with those treated with surgical repair...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28051883/hydrogels-for-precision-meniscus-tissue-engineering-a-comprehensive-review
#2
Ana Rey-Rico, Magali Cucchiarini, Henning Madry
The meniscus plays a pivotal role to preserve the knee joint homeostasis. Lesions to the meniscus are frequent, have a reduced ability to heal, and may induce tibiofemoral osteoarthritis. Current reconstructive therapeutic options mainly focus on the treatment of lesions in the peripheral vascularized region. In contrast, few approaches are capable of stimulating repair of damaged meniscal tissue in the central, avascular portion. Tissue engineering approaches are of high interest to repair or replace damaged meniscus tissue in this area...
January 4, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28028568/arthroscopic-all-inside-ramp-lesion-repair-using-the-posterolateral-transseptal-portal-view
#3
Sohrab Keyhani, Jin Hwan Ahn, René Verdonk, Mehran Soleymanha, Mohammadreza Abbasian
PURPOSE: The purpose of this study was to evaluate and describe the clinical results and outcomes of a novel method for all-inside suture repair of medial meniscus ramp lesions through posteromedial and posterolateral transseptal portals during anterior cruciate ligament (ACL) reconstruction. Further, this investigation compared the posterolateral view to the notch view for diagnosis and repair. METHODS: Between 2011 and 2014, 166 patients had ramp lesions concomitantly with ACL injury; 128 patients (107 men and 21 women) were enrolled in the study after qualification...
December 27, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28025802/the-effect-of-tissue-surface-modification-with-collagenase-and-addition-of-tgf-%C3%AE-3-on-the-healing-potential-of-meniscal-tears-repaired-with-tissue-glues-in-vitro
#4
Agnieszka Izabela Bochyńska, Gerjon Hannink, Renate Verhoeven, Dirk W Grijpma, Pieter Buma
The aim of the current in vitro study was to investigate if tissue surface modification with collagenase and addition of the TGF-β3 can increase the number of cells present in meniscus tears repaired with the use of newly developed tissue adhesives based on isocyanate-terminated block copolymers. Cylindrical explants were harvested from the inner part of bovine menisci. To simulate a full-thickness tear, the central core of the explants was removed and glued back into the defect, with or without incubation in collagenase solution prior to gluing...
January 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28012004/post-operative-deformation-and-extrusion-of-the-discoid-lateral-meniscus-following-a-partial-meniscectomy-with-repair
#5
Tomohiko Matsuo, Kazutaka Kinugasa, Kousuke Sakata, Tomoki Ohori, Tatsuo Mae, Masayuki Hamada
PURPOSE: The purpose of this study was to investigate the morphology of the discoid lateral meniscus sequentially following a partial meniscectomy with repair using magnetic resonance imaging (MRI). METHODS: Nine patients with a symptomatic discoid lateral meniscus with a peripheral tear were enrolled in this study, and a partial meniscectomy with repair was performed arthroscopically. An MRI examination was performed 2 weeks after surgery (before weight bearing was permitted) and again 6 months after surgery (when sporting activities could resume)...
December 23, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28005443/identification-and-characterization-of-adult-mouse-meniscus-stem-progenitor-cells
#6
Laura W Gamer, Rui Rui Shi, Ashira Gendelman, Dylan Mathewson, Jackson Gamer, Vicki Rosen
Meniscal damage is a common problem that accelerates the onset of knee osteoarthritis. Stem cell based tissue engineering treatment approaches have shown promise in preserving meniscal tissue and restoring meniscal function. The purpose of our study was to identify meniscus-derived stem/progenitor cells (MSPCs) from mouse, a model system that allows for in vivo analysis of the mechanisms underlying meniscal injury and healing. MSPCs were isolated from murine menisci grown in explant culture and characterized for stem cell properties...
December 22, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/28003668/concurrent-lateral-meniscal-repair-with-anterior-cruciate-ligament-reconstruction-induces-the-extrusion-of-the-lateral-meniscus-assessments-of-magnetic-resonance-images
#7
Naoko Kashihara, Takayuki Furumatsu, Yuya Kodama, Takaaki Tanaka, Toshifumi Ozaki
Concurrent meniscal repair with anterior cruciate ligament (ACL) reconstruction has shown good clinical outcomes, but it has a considerable risk of progressing to post-traumatic osteoarthritis of the knee. Here we investigated postoperative changes in the position of the lateral meniscus (LM) and assessed the short-term clinical results after concurrent LM repair with ACL reconstruction. Twentyseven patients underwent LM repair of a peripheral longitudinal tear concomitant with ACL reconstruction. We evaluated the preoperative and postoperative values of the Lysholm score and anteroposterior instability...
December 2016: Acta Medica Okayama
https://www.readbyqxmd.com/read/28002905/arthroscopic-all-inside-treatment-of-popliteomeniscal-fascicles-tears-surgical-technique-and-results-from-the-first-6-consecutive-patients
#8
R Simonetta, G Di Vico, R Papalia, S Vasta, V Denaro
Athletes whose knees are subjected to sudden changes of direction and high jumps such as martial arts athletes, dancers, wrestlers and football players are at higher risk of injuring popliteomeniscal fascicles. Painful squatting and mechanical symptoms such as locking sensation are common. Current available treatments includes open or arthroscopic in repair. Arthroscopic repair with all-inside device can relieve symptoms and restore knee function. Six patients from two surgical centers with isolated popliteomeniscal fascicles tears were treated with arthroscopic all-inside repair...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28002904/the-meniscus-vascularization-the-direct-correlation-with-tissue-composition-for-tissue-engineering-purposes
#9
A Di Giancamillo, L Mangiavini, I Tessaro, A Marmotti, R Scurati, G M Peretti
Meniscal lesions still represent an unsolved problem in clinical practice. Like the articular cartilage, meniscus has a scarce healing potential. Thus, when this tissue is damaged, the joint biomechanics is completely altered, leading to the development and progression of premature osteoarthritis. Therefore, in the last years, several tissue-engineering strategies have been developed to regenerate the meniscus with debated results. The comprehension of complex processes underlying meniscus maturation and structure is essential for a correct approach for the generation of a biomimetic meniscal substitute...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27956232/changes-in-contact-area-in-meniscus-horizontal-cleavage-tears-subjected-to-repair-and-resection
#10
Brandon S Beamer, Kempland C Walley, Stephen Okajima, Ohan S Manoukian, Miguel Perez-Viloria, Joseph P DeAngelis, Arun J Ramappa, Ara Nazarian
PURPOSE: To assess the changes in tibiofemoral contact pressure and contact area in human knees with a horizontal cleavage tear before and after treatment. METHODS: Ten human cadaveric knees were tested. Pressure sensors were placed under the medial meniscus and the knees were loaded at twice the body weight for 20 cycles at 0°, 10°, and 20° of flexion. Contact area and pressure were recorded for the intact meniscus, the meniscus with a horizontal cleavage tear, after meniscal repair, after partial meniscectomy (single leaflet), and after subtotal meniscectomy (double leaflet)...
December 9, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27940573/knee-osteoarthritis-is-associated-with-previous-meniscus-and-anterior-cruciate-ligament-surgery-among-elite-college-american-football-athletes
#11
Matthew V Smith, Jeffrey J Nepple, Rick W Wright, Matthew J Matava, Robert H Brophy
BACKGROUND: Football puts athletes at risk for knee injuries such meniscus and anterior cruciate ligament (ACL) tears, which are associated with the development of osteoarthritis (OA). Previous knee surgery, player position, and body mass index (BMI) may be associated with knee OA. HYPOTHESIS: In elite football players undergoing knee magnetic resonance imaging at the National Football League's Invitational Combine, the prevalence of knee OA is associated with previous knee surgery and BMI...
December 9, 2016: Sports Health
https://www.readbyqxmd.com/read/27932332/the-anterolateral-capsule-of-the-knee-behaves-like-a-sheet-of-fibrous-tissue
#12
Daniel Guenther, Amir A Rahnemai-Azar, Kevin M Bell, Sebastián Irarrázaval, Freddie H Fu, Volker Musahl, Richard E Debski
BACKGROUND: The function of the anterolateral capsule of the knee has not been clearly defined. However, the contribution of this region of the capsule to knee stability in comparison with other anterolateral structures can be determined by the relative force that each structure carries during loading of the knee. PURPOSE/HYPOTHESIS: The purpose of this study was to determine the forces in the anterolateral structures of the intact and anterior cruciate ligament (ACL)-deficient knee in response to an anterior tibial load and internal tibial torque...
December 8, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27929701/effect-of-serum-and-platelet-rich-plasma-on-human-early-or-advanced-degenerative-meniscus-cells
#13
Undine Freymann, Lucia Degrassi, Jan Philipp Krüger, Sebastian Metzlaff, Michaela Endres, Wolf Petersen
PURPOSE: The purpose of this in vitro study was to evaluate the migratory, proliferating & extracellular matrix (ECM) forming effect of human serum (HS) and platelet-rich plasma (PRP) on meniscus cells derived from human knees with early or advanced degenerative changes. MATERIALS AND METHODS: Medial menisci from knees with early degenerative changes (n=5; mean Kellgren score of 1) undergoing arthroscopic meniscal surgery and advanced degenerative changes (n=5; mean Kellgren score of 4) undergoing total knee replacement were collected...
December 8, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/27919916/posterior-meniscal-root-repairs-outcomes-of-an-anatomic-transtibial-pull-out-technique
#14
Robert F LaPrade, Lauren M Matheny, Samuel G Moulton, Evan W James, Chase S Dean
BACKGROUND: Outcomes after transtibial pull-out repair for posterior meniscal root tears remain underreported, and factors that may affect outcomes are unknown. PURPOSE/HYPOTHESIS: The purpose of this study was to compare patient-centered outcomes after transtibial pull-out repair for posterior root tears in patients <50 and ≥50 years of age. We hypothesized that improvement in function and activity level at minimum 2-year follow-up would be similar among patients <50 years of age compared with patients ≥50 years and among patients undergoing medial versus lateral root repairs...
December 5, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27895039/region-specific-effect-of-the-decellularized-meniscus-extracellular-matrix-on-mesenchymal-stem-cell-based-meniscus-tissue-engineering
#15
Kazunori Shimomura, Benjamin B Rothrauff, Rocky S Tuan
BACKGROUND: The meniscus is the most commonly injured knee structure, and surgical repair is often ineffective. Tissue engineering-based repair or regeneration may provide a needed solution. Decellularized, tissue-derived extracellular matrices (ECMs) have received attention for their potential use as tissue-engineered scaffolds. In considering meniscus-derived ECMs (mECMs) for meniscus tissue engineering, it is noteworthy that the inner and outer regions of the meniscus have different structural and biochemical features, potentially directing the differentiation of cells toward region-specific phenotypes...
November 28, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27894171/diagnosis-and-treatment-of-discoid-meniscus
#16
REVIEW
Jae-Gyoon Kim, Seung-Woo Han, Dae-Hee Lee
There is a greater incidence of discoid meniscus in Asian countries than in Western countries, and bilateral discoid menisci are also common. The discoid meniscus may be a congenital anomaly, and genetics or family history may play a role in the development of discoid menisci. Because the histology of discoid meniscus is different from that of normal meniscus, it is prone to tearing. Individuals with a discoid meniscus can be asymptomatic or symptomatic. Asymptomatic discoid menisci do not require treatment...
December 1, 2016: Knee Surgery & related Research
https://www.readbyqxmd.com/read/27894146/variables-associated-with-chondral-and-meniscal-injuries-in-anterior-cruciate-ligament-surgery
#17
E Lyle Cain, Glenn S Fleisig, Brent A Ponce, Hikel A Boohaker, Martha P George, Gerald McGwin, James R Andrews, Lawrence J Lemak, William G Clancy, Jeffrey R Dugas
This article aims to evaluate factors associated with chondral and meniscal lesions in primary and revision anterior cruciate ligament (ACL) reconstructions. ACL reconstructions from 2001 to 2008 at a single institution were retrospectively analyzed. Logistic regression was used to estimate the association between chondral and meniscal injuries and age, gender, tear chronicity, additional ligamentous injuries, sport type, and participation level. Of the 3,040 ACL reconstructions analyzed, 90.4% were primary reconstructions and 9...
November 28, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27893158/articular-cartilage-scores-in-cranial-cruciate-ligament-deficient-dogs-with-or-without-bucket-handle-tears-of-the-medial-meniscus
#18
Kathryn Kaufman, Brian S Beale, Howard D Thames, W Brian Saunders
OBJECTIVE: To compare articular cartilage scores in cranial cruciate ligament (CCL)-deficient dogs with or without concurrent bucket handle tears (BHT) of the medial meniscus. STUDY DESIGN: Retrospective case series. ANIMALS: Client-owned dogs treated with arthroscopy and tibial plateau leveling osteotomy or extracapsular repair for complete CCL rupture (290 stifles from 264 dogs). METHODS: Medical records and arthroscopic images were reviewed...
November 28, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27892399/a-suture-technique-for-easier-reduction-and-repair-of-bucket-handle-meniscal-tears-while-using-the-all-inside-devices
#19
Engin Çetinkaya, Ersin Kuyucu, Murat Gül, Osman Lapçin, Kutalmış Albayrak, Sarper Gürsu
Arthroscopic repair of bucket-handle meniscal tears is difficult due to their complex pathology. Many meniscal repair techniques such as all-inside, inside-out, and outside-in have been described for the treatment of these tears. Loss of reduction is a likely complication with the use of new-generation, all-inside suture instruments, as the tip of the needle is extracted following advancement of the first implant behind the capsule. The complication may be encountered quite often and renders the use of the meniscus repair instrument unusable and causes an irreparable iatrogenic injury in the meniscus...
2016: SICOT-J
https://www.readbyqxmd.com/read/27876676/anatomical-region-dependent-enhancement-of-3-dimensional-chondrogenic-differentiation-of-human-mesenchymal-stem-cells-by-soluble-meniscus-extracellular-matrix
#20
Benjamin B Rothrauff, Kazunori Shimomura, Riccardo Gottardi, Peter G Alexander, Rocky S Tuan
: Extracellular matrix (ECM) derived from decellularized tissues has been found to promote tissue neogenesis, most likely mediated by specific biochemical and physical signaling motifs that promote tissue-specific differentiation of progenitor cells. Decellularized ECM has been suggested to be efficacious for the repair of tissue injuries. However, decellularized meniscus contains a dense collagenous structure, which impedes cell seeding and infiltration and is not readily applicable for meniscus repair...
November 19, 2016: Acta Biomaterialia
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