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JOURNAL ARTICLE
Bence Marosi, Béla Kádár, Anna Bruzsa, Laura Kocsis, Katalin Kamotsay, János Sinkó, Bálint Gergely Szabó, Botond Lakatos
INTRODUCTION: Over the past decade, enterococcal bloodstream infection (BSI) shows increasing incidence globally among the elderly and in patients with comorbidities. In this study, we aimed to assess microbiological and clinical characteristics and long-term outcomes of BSIs caused by Enterococcus spp. in adult patients with and without active onco-hematological malignancies hospitalized at a national referral institute. METHODS: A prospective analysis of consecutive enterococcal BSI cases was conducted in the National Institute of Hematology and Infectious Diseases (Budapest, Hungary) between December 2019 and April 2022...
March 27, 2024: European Journal of Microbiology & Immunology
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JOURNAL ARTICLE
Marijana Virijevic, Nada Kraguljac-Kurtovic, Mirjana Mitrovic, Ljubomir Jakovic, Zoran Bukumuric, Nikola Pantic, Nikica Sabljic, Zlatko Pravdic, Mirjana Cvetkovic, Vesna Knezevic, Tijana Dragovic-Ivancevic, Irena Djunić, Jovan Rajic, Violeta Milosevic, Milena Todorovic-Balint, Ana Vidovic, Nada Suvajdzic-Vukovic
Examination of central nervous system (CNS) involvement is not routine diagnostic practice in adult patients with acute myeloid leukemia (AML). Therefore, many asymptomatic patients with CNS involvement might go undetected. The effect of CNS involvement on the AML disease course is not well defined, with conflicting results regarding clinical outcome. This study aimed to determine the incidence of asymptomatic CNS involvement in AML estimated by multiparametric flow cytometry of cerebrospinal fluid (MFC-CSF) at diagnosis, the related potential risk factors, and prognosis...
March 2024: Hematological Oncology
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JOURNAL ARTICLE
Esperanza Naredo, Maria Antonietta D'Agostino, Lene Terslev, Carlos Pineda, M Isabel Miguel, Joan Blasi, George A Bruyn, Marion C Kortekaas, Peter Mandl, Rodina Nestorova, Marcin Szkudlarek, Plamen Todorov, Violeta Vlad, Priscilla Wong, Catherine Bakewell, Emilio Filippucci, Alen Zabotti, Mihaela Micu, Florentin Vreju, Mohamed Mortada, José Alexandre Mendonça, Carlos A Guillen-Astete, Otto Olivas-Vergara, Annamaria Iagnocco, Petra Hanova, Ilaria Tinazzi, Peter V Balint, Sibel Zehra Aydin, David Kane, Helen Keen, Gurjit S Kaeley, Ingrid Möller
OBJECTIVES: The main objective was to generate a GLobal OMERACT Ultrasound DActylitis Score (GLOUDAS) in psoriatic arthritis and to test its reliability. To this end, we assessed the validity, feasibility and applicability of ultrasound assessment of finger entheses to incorporate them into the scoring system. METHODS: The study consisted of a stepwise process. First, in cadaveric specimens, we identified enthesis sites of the fingers by ultrasound and gross anatomy, and then verified presence of entheseal tissue in histological samples...
April 4, 2024: Annals of the Rheumatic Diseases
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JOURNAL ARTICLE
Zoltán Lippai, Bálint Péterfia, Gergő Papp, Katalin Dezső, Gábor Bedics, Zsuzsanna Pápai, Meindert H Lamers, Rosan Cm Kuin, Károly Szuhai, Zoltán Sápi
INTRODUCTION: Dedifferentiated liposarcoma (DDLPS) is a common form of liposarcoma with challenging treatment modalities. Pan-TRK immunopositivity can be often observed without NTRK gene fusion in soft tissue sarcomas with myogenic differentiation. Expression and the role of NTRK in DDLPS are under-studied. We sought to identify activating mutations of the NTRK genes. MATERIALS AND METHODS: 131 DDLPS patients were selected for pan-TRK immunohistochemistry and positive cases were analyzed by Sanger sequencing for NTRK1, NTRK2 and NTRK3 genes...
March 14, 2024: European Journal of Cancer
#25
REVIEW
Asher Hudson, Alexander Mullens, Sarah Hind, Tiffany Jamann, Peter Balint-Kurti
The pattern-triggered immunity (PTI) response is triggered at the plant cell surface by the recognition of microbe-derived molecules known as microbe- or pathogen-associated molecular patterns or molecules derived from compromised host cells called damage-associated molecular patterns. Membrane-localized receptor proteins, known as pattern recognition receptors, are responsible for this recognition. Although much of the machinery of PTI is conserved, natural variation for the PTI response exists within and across species with respect to the components responsible for pattern recognition, activation of the response, and the strength of the response induced...
March 2024: Molecular Plant Pathology
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JOURNAL ARTICLE
Arvin R Akhavan, Amy V Kontrick, Haley Egan, Stephanie A Balint, Bryan G Kane, Joseph B House, Charles S Graffeo, D Mark Courtney, Dave W Lu
INTRODUCTION: Emergency medicine (EM) has historically been among the most competitive specialties in the United States. However, in 2022 and 2023, 219 of 2921 and 554 of 3010 respective National Resident Matching Program positions were initially unfilled. Medical students' selection of a medical specialty is a complex process. To better understand recent trends in the EM residency match, this qualitative study explored through one-on-one interviews the rationale of senior medical students who seriously considered EM but ultimately pursued another specialty...
April 2024: AEM Education and Training
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JOURNAL ARTICLE
Péter Bacsur, Panu Wetwittayakhlang, Tamás Resál, Emese Földi, Béla Vasas, Bernadett Farkas, Mariann Rutka, Talat Bessissow, Waqqas Afif, Anita Bálint, Anna Fábián, Renáta Bor, Zoltán Szepes, Klaudia Farkas, Peter L Lakatos, Tamás Molnár
BACKGROUND: Different endoscopic scoring systems for assessing ulcerative colitis (UC) severity are available. However, most of them are not correlated with disease extent. OBJECTIVES: Our study aimed to compare the predictive value of the PanMay score versus the endoscopic Mayo (MES), Ulcerative Colitis Endoscopic Index of Severity (UCEIS), and Dublin score in predicting long-term outcomes of UC. DESIGN: This retrospective study enrolled consecutive UC patients who underwent colonoscopy before at least a 3-year follow-up...
2024: Therapeutic Advances in Gastroenterology
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JOURNAL ARTICLE
Daniel Krafft, Clifton G Scarboro, William Hsieh, Colleen Doherty, Peter Balint-Kurti, Michael Kudenov
Automation of plant phenotyping using data from high-dimensional imaging sensors is on the forefront of agricultural research for its potential to improve seasonal yield by monitoring crop health and accelerating breeding programs. A common challenge when capturing images in the field relates to the spectral reflection of sunlight (glare) from crop leaves that, at certain solar incidences and sensor viewing angles, presents unwanted signals. The research presented here involves the convergence of 2 parallel projects to develop a facile algorithm that can use polarization data to decouple light reflected from the surface of the leaves and light scattered from the leaf's tissue...
2024: Plant phenomics: a science partner journal
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JOURNAL ARTICLE
Andrew J Hamer, István Czeglédi, Blanka Gál, Péter Sály, Zoltán Szalóky, Bálint Preiszner, Tibor Erős
River-floodplain ecosystems play a crucial role in connecting landscape patches through hydrological connectivity, but they are among the most threatened ecosystems. Floodplains provide important habitat for amphibians by connecting aquatic and terrestrial habitats. Modifications to floodplain hydrology can impact amphibian communities, yet few studies have examined amphibian metacommunities in floodplain wetlands.In this study, we assessed patterns in amphibian breeding abundance in one of the largest floodplains of the Danube River, Hungary, relative to hydrological connectivity and multi-scale variables at 30 waterbody sites...
August 2023: Freshwater Biology
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JOURNAL ARTICLE
Bálint Károly Lakatos, Zvonimir Rako, Ádám Szijártó, Bruno R Brito da Rocha, Manuel J Richter, Alexandra Fábián, Henning Gall, Hossein A Ghofrani, Nils Kremer, Werner Seeger, Daniel Zedler, Selin Yildiz, Athiththan Yogeswaran, Béla Merkely, Khodr Tello, Attila Kovács
Three-dimensional (3D) echocardiography-derived right ventricular (RV) ejection fraction (EF) and global longitudinal strain (GLS) are valuable RV functional markers; nevertheless, they are substantially load-dependent. Global myocardial work index (GMWI) is a novel parameter calculated by the area of the RV pressure-strain loop. By adjusting myocardial deformation to instantaneous pressure, it may reflect contractility. To test this hypothesis, we enrolled 60 patients who underwent RV pressure-conductance catheterization to determine load-independent markers of RV contractility and ventriculo-arterial coupling...
March 18, 2024: Journal of Heart and Lung Transplantation
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JOURNAL ARTICLE
Elena Surkova, Bálint Károly Lakatos, Alexandra Fábián, Attila Kovács, Roxy Senior, Wei Li
We aimed to evaluate clinical and prognostic significance of myocardial work parameters of the systemic right ventricle (SRV). Thirty-eight patients with the SRV underwent echocardiographic assessment of the SRV systolic function including 3D-echocardiography derived ejection fraction, 2D longitudinal strain and myocardial work analysis. The study endpoint was the combination of all-cause mortality and heart transplantation. Global constructive work (GCW) and global work index (GWI) demonstrated moderate correlation with the 3DE-derived SRV ejection fraction (EF) (Rho 0...
March 20, 2024: International Journal of Cardiovascular Imaging
#32
REVIEW
Tünde Kilencz, Sára Bálint, Beatrix Mersich, Szilvia Papp, Ákos Ferencz, Lívia Balogh, Attila József Pulay, Kinga Farkas, János Réthelyi
Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset mental disorder, demonstrates genetical effects, and is characterized by attention deficit, hyperactivity, and impulsivity. While ADHD was previously only considered a childhood disorder, longitudinal studies over the past decades have proven that in a significant number of cases, the symptoms of the disorder can also be detected in adulthood, and therefore affects 2-4% of the adult population. In Hungary, adult ADHD programs started about 20 years ago and has been able to provide help to many adults living with ADHD...
2024: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
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JOURNAL ARTICLE
Róbert Wernigg, Bálint Hajduska-Dér
In recent decades a global problem in mental health has been the increase in the relative proportion of patients who do not receive care, which is associated with loss of life years and deterioration in quality of life. The practical application of artificial intelligence (AI) can help in the fields of data analysis, diagnosis, therapy planning, among others in psychiatric care, thus reducing the human resource input. Today's artificial narrow intelligence (ANI), also known as weak AI, can recognise patterns and correlations in large data sets with the help of machine learning procedures and to make autonomous decisions while making its own refinements...
2024: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
#34
JOURNAL ARTICLE
Bálint Jász, Szilvia Ambrus, Tamás Garay, Péter Schmidt, Péter Hermann, Szandra Körmendi, Máté Jász
BACKGROUND: Finding and registering the maxillary-mandibular jaw relation is crucial in dental practice. Several comparative studies have been conducted to investigate the reproducibility and accuracy of techniques for determining the centric relation (CR) position of the mandible. The aim of our study was to determine which of seven different CR determination methods had the smallest deviation from the theoretical zero with the help of a digital mandibular motion analyser. The chosen theoretical zero position, the maximal intercuspal position (MIP), is the most reproducible and widely used position...
March 18, 2024: BMC Oral Health
#35
JOURNAL ARTICLE
A Cole Burton, Christopher Beirne, Kaitlyn M Gaynor, Catherine Sun, Alys Granados, Maximilian L Allen, Jesse M Alston, Guilherme C Alvarenga, Francisco Samuel Álvarez Calderón, Zachary Amir, Christine Anhalt-Depies, Cara Appel, Stephanny Arroyo-Arce, Guy Balme, Avi Bar-Massada, Daniele Barcelos, Evan Barr, Erika L Barthelmess, Carolina Baruzzi, Sayantani M Basak, Natalie Beenaerts, Jonathan Belmaker, Olgirda Belova, Branko Bezarević, Tori Bird, Daniel A Bogan, Neda Bogdanović, Andy Boyce, Mark Boyce, LaRoy Brandt, Jedediah F Brodie, Jarred Brooke, Jakub W Bubnicki, Francesca Cagnacci, Benjamin Scott Carr, João Carvalho, Jim Casaer, Rok Černe, Ron Chen, Emily Chow, Marcin Churski, Connor Cincotta, Duško Ćirović, T D Coates, Justin Compton, Courtney Coon, Michael V Cove, Anthony P Crupi, Simone Dal Farra, Andrea K Darracq, Miranda Davis, Kimberly Dawe, Valerie De Waele, Esther Descalzo, Tom A Diserens, Jakub Drimaj, Martin Duľa, Susan Ellis-Felege, Caroline Ellison, Alper Ertürk, Jean Fantle-Lepczyk, Jorie Favreau, Mitch Fennell, Pablo Ferreras, Francesco Ferretti, Christian Fiderer, Laura Finnegan, Jason T Fisher, M Caitlin Fisher-Reid, Elizabeth A Flaherty, Urša Fležar, Jiří Flousek, Jennifer M Foca, Adam Ford, Barbara Franzetti, Sandra Frey, Sarah Fritts, Šárka Frýbová, Brett Furnas, Brian Gerber, Hayley M Geyle, Diego G Giménez, Anthony J Giordano, Tomislav Gomercic, Matthew E Gompper, Diogo Maia Gräbin, Morgan Gray, Austin Green, Robert Hagen, Robert Bob Hagen, Steven Hammerich, Catharine Hanekom, Christopher Hansen, Steven Hasstedt, Mark Hebblewhite, Marco Heurich, Tim R Hofmeester, Tru Hubbard, David Jachowski, Patrick A Jansen, Kodi Jo Jaspers, Alex Jensen, Mark Jordan, Mariane C Kaizer, Marcella J Kelly, Michel T Kohl, Stephanie Kramer-Schadt, Miha Krofel, Andrea Krug, Kellie M Kuhn, Dries P J Kuijper, Erin K Kuprewicz, Josip Kusak, Miroslav Kutal, Diana J R Lafferty, Summer LaRose, Marcus Lashley, Richard Lathrop, Thomas E Lee, Christopher Lepczyk, Damon B Lesmeister, Alain Licoppe, Marco Linnell, Jan Loch, Robert Long, Robert C Lonsinger, Julie Louvrier, Matthew Scott Luskin, Paula MacKay, Sean Maher, Benoît Manet, Gareth K H Mann, Andrew J Marshall, David Mason, Zara McDonald, Tracy McKay, William J McShea, Matt Mechler, Claude Miaud, Joshua J Millspaugh, Claudio M Monteza-Moreno, Dario Moreira-Arce, Kayleigh Mullen, Christopher Nagy, Robin Naidoo, Itai Namir, Carrie Nelson, Brian O'Neill, M Teague O'Mara, Valentina Oberosler, Christian Osorio, Federico Ossi, Pablo Palencia, Kimberly Pearson, Luca Pedrotti, Charles E Pekins, Mary Pendergast, Fernando F Pinho, Radim Plhal, Xochilt Pocasangre-Orellana, Melissa Price, Michael Procko, Mike D Proctor, Emiliano Esterci Ramalho, Nathan Ranc, Slaven Reljic, Katie Remine, Michael Rentz, Ronald Revord, Rafael Reyna-Hurtado, Derek Risch, Euan G Ritchie, Andrea Romero, Christopher Rota, Francesco Rovero, Helen Rowe, Christian Rutz, Marco Salvatori, Derek Sandow, Christopher M Schalk, Jenna Scherger, Jan Schipper, Daniel G Scognamillo, Çağan H Şekercioğlu, Paola Semenzato, Jennifer Sevin, Hila Shamon, Catherine Shier, Eduardo A Silva-Rodríguez, Magda Sindicic, Lucy K Smyth, Anil Soyumert, Tiffany Sprague, Colleen Cassady St Clair, Jennifer Stenglein, Philip A Stephens, Kinga Magdalena Stępniak, Michael Stevens, Cassondra Stevenson, Bálint Ternyik, Ian Thomson, Rita T Torres, Joan Tremblay, Tomas Urrutia, Jean-Pierre Vacher, Darcy Visscher, Stephen L Webb, Julian Weber, Katherine C B Weiss, Laura S Whipple, Christopher A Whittier, Jesse Whittington, Izabela Wierzbowska, Martin Wikelski, Jacque Williamson, Christopher C Wilmers, Todd Windle, Heiko U Wittmer, Yuri Zharikov, Adam Zorn, Roland Kays
Wildlife must adapt to human presence to survive in the Anthropocene, so it is critical to understand species responses to humans in different contexts. We used camera trapping as a lens to view mammal responses to changes in human activity during the COVID-19 pandemic. Across 163 species sampled in 102 projects around the world, changes in the amount and timing of animal activity varied widely. Under higher human activity, mammals were less active in undeveloped areas but unexpectedly more active in developed areas while exhibiting greater nocturnality...
March 18, 2024: Nature Ecology & Evolution
#36
JOURNAL ARTICLE
Laure Gossec, Andreas Kerschbaumer, Ricardo J O Ferreira, Daniel Aletaha, Xenofon Baraliakos, Heidi Bertheussen, Wolf-Henning Boehncke, Bente Appel Esbensen, Iain B McInnes, Dennis McGonagle, Kevin L Winthrop, Andra Balanescu, Peter V Balint, Gerd R Burmester, Juan D Cañete, Pascal Claudepierre, Lihi Eder, Merete Lund Hetland, Annamaria Iagnocco, Lars Erik Kristensen, Rik Lories, Rubén Queiro, Daniele Mauro, Helena Marzo-Ortega, Philip J Mease, Peter Nash, Wendy Wagenaar, Laura Savage, Georg Schett, Stephanie J W Shoop-Worrall, Yoshiya Tanaka, Filip E Van den Bosch, Annette van der Helm-van Mil, Alen Zabotti, Désirée van der Heijde, Josef S Smolen
OBJECTIVE: New modes of action and more data on the efficacy and safety of existing drugs in psoriatic arthritis (PsA) required an update of the EULAR 2019 recommendations for the pharmacological treatment of PsA. METHODS: Following EULAR standardised operating procedures, the process included a systematic literature review and a consensus meeting of 36 international experts in April 2023. Levels of evidence and grades of recommendations were determined. RESULTS: The updated recommendations comprise 7 overarching principles and 11 recommendations, and provide a treatment strategy for pharmacological therapies...
March 18, 2024: Annals of the Rheumatic Diseases
#37
JOURNAL ARTICLE
Borbála Vattay, Melinda Boussoussou, Milán Vecsey-Nagy, Márton Kolossváry, Dénes Juhász, Nóra Kerkovits, Hanna Balogh, Norbert Nagy, Miklós Vértes, Máté Kiss, Anikó Kubovje, Béla Merkely, Pál Maurovich Horvat, Bálint Szilveszter
PURPOSE: We aimed to identify the optimal reconstruction settings based on qualitative and quantitative image quality parameters on standard and ultra-high resolution (UHR) images using photon-counting CT (PCCT). METHOD: We analysed 45 patients, 29 with standard and 16 with UHR acquisition, applying both smoother and sharper kernel settings. Coronary CT angiography images were performed on a dual-source PCCT system using standard (0.4/0.6 mm slice thickness, Bv40/Bv44 kernels, QIR levels 0-4) or UHR acquisition (0...
March 12, 2024: European Journal of Radiology
#38
JOURNAL ARTICLE
Lili Holub, Bálint Gergely Szabó, Lőrinc Závorszky, Rózsa Hümpfner, Péter Andréka, Gellért Balázs Karvaly, Botond Lakatos
No abstract text is available yet for this article.
March 17, 2024: Orvosi Hetilap
#39
Aiden Ford, Zsofia A Kovacs-Balint, Arick Wang, Eric Feczko, Eric Earl, Óscar Miranda-Domínguez, Longchuan Li, Martin Styner, Damien Fair, Warren Jones, Jocelyne Bachevalier, Mar M Sánchez
No abstract text is available yet for this article.
March 15, 2024: Developmental Cognitive Neuroscience
#40
REVIEW
Xenia Gonda, Sara Balint, Janos Miklos Rethelyi, Peter Dome
While the currently prevailing theory of ADHD postulates a neurobiological background and core deficits of behavioural inhibition and executive functioning as the basis of ADHD symptoms, our current conceptualisation also acknowledges the essential contributory role of psychosocial, ecological, and cognitive factors. Considering the multifactorial background of ADHD, its treatment equally needs to be multifactorial involving, besides pharmacotherapy, skill development and psychotherapy as well, especially if we postulate the increasing contribution of social factors in the background of the increasing burden of ADHD...
March 14, 2024: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
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