keyword
MENU ▼
Read by QxMD icon Read
search

Architecture

keyword
https://www.readbyqxmd.com/read/28445803/jetvalve-rapid-manufacturing-of-biohybrid-scaffolds-for-biomimetic-heart-valve-replacement
#1
Andrew K Capulli, Maximillian Y Emmert, Francesco S Pasqualini, Debora Kehl, Etem Caliskan, Johan U Lind, Sean P Sheehy, Sung Jin Park, Seungkuk Ahn, Benedikt Weber, Josue A Goss, Simon P Hoerstrup, Kevin Kit Parker
Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. To overcome these limitations, in situ tissue engineering approaches aim to develop scaffold materials and manufacturing processes that elicit endogenous tissue remodeling and repair. Yet despite recent advances in synthetic materials manufacturing, there remains a lack of cell-free, automated approaches for rapidly producing biomimetic heart valve scaffolds...
April 18, 2017: Biomaterials
https://www.readbyqxmd.com/read/28445524/live-imaging-of-primary-ocular-vasculature-formation-in-zebrafish
#2
Tetsuya Hashiura, Eiji Kimura, Shizuko Fujisawa, Sayuri Oikawa, Shigenori Nonaka, Daijiro Kurosaka, Jiro Hitomi
Ocular vasculature consists of the central retinal and ciliary vascular systems, which are essential to maintaining visual function. Many researchers have attempted to determine their origins and development; however, the detailed, stepwise process of ocular vasculature formation has not been established. In zebrafish, two angioblast clusters, the rostral and midbrain organizing centers, form almost all of the cranial vasculature, including the ocular vasculature, and these are from where the cerebral arterial and venous angioblast clusters, respectively, differentiate...
2017: PloS One
https://www.readbyqxmd.com/read/28445521/next-generation-sequencing-to-dissect-the-genetic-architecture-of-kng1-and-f11-loci-using-factor-xi-levels-as-an-intermediate-phenotype-of-thrombosis
#3
Laura Martin-Fernandez, Giovana Gavidia-Bovadilla, Irene Corrales, Helena Brunel, Lorena Ramírez, Sonia López, Juan Carlos Souto, Francisco Vidal, José Manuel Soria
Venous thromboembolism is a complex disease with a high heritability. There are significant associations among Factor XI (FXI) levels and SNPs in the KNG1 and F11 loci. Our aim was to identify the genetic variation of KNG1 and F11 that might account for the variability of FXI levels. The KNG1 and F11 loci were sequenced completely in 110 unrelated individuals from the GAIT-2 (Genetic Analysis of Idiopathic Thrombophilia 2) Project using Next Generation Sequencing on an Illumina MiSeq. The GAIT-2 Project is a study of 935 individuals in 35 extended Spanish families selected through a proband with idiopathic thrombophilia...
2017: PloS One
https://www.readbyqxmd.com/read/28445459/the-effect-of-illumination-on-the-formation-of-metal-halide-perovskite-films
#4
Amita Ummadisingu, Ludmilla Steier, Ji-Youn Seo, Taisuke Matsui, Antonio Abate, Wolfgang Tress, Michael Grätzel
Optimizing the morphology of metal halide perovskite films is an important way to improve the performance of solar cells when these materials are used as light harvesters, because film homogeneity is correlated with photovoltaic performance. Many device architectures and processing techniques have been explored with the aim of achieving high-performance devices, including single-step deposition, sequential deposition and anti-solvent methods. Earlier studies have looked at the influence of reaction conditions on film quality, such as the concentration of the reactants and the reaction temperature...
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28445419/embedded-spherical-localization-for-micro-underwater-vehicles-based-on-attenuation-of-electro-magnetic-carrier-signals
#5
Daniel-André Duecker, A René Geist, Michael Hengeler, Edwin Kreuzer, Marc-André Pick, Viktor Rausch, Eugen Solowjow
Self-localization is one of the most challenging problems for deploying micro autonomous underwater vehicles ( μ AUV) in confined underwater environments. This paper extends a recently-developed self-localization method that is based on the attenuation of electro-magnetic waves, to the μ AUV domain. We demonstrate a compact, low-cost architecture that is able to perform all signal processing steps present in the original method. The system is passive with one-way signal transmission and scales to possibly large μ AUV fleets...
April 26, 2017: Sensors
https://www.readbyqxmd.com/read/28445417/ins-gnss-integration-for-aerobatic-flight-applications-and-aircraft-motion-surveying
#6
Edgar L V Hinüber, Christian Reimer, Tim Schneider, Michael Stock
This paper presents field tests of challenging flight applications obtained with a new family of lightweight low-power INS/GNSS (inertial navigation system/global satellite navigation system) solutions based on MEMS (micro-electro-mechanical- sensor) machined sensors, being used for UAV (unmanned aerial vehicle) navigation and control as well as for aircraft motion dynamics analysis and trajectory surveying. One key is a 42+ state extended Kalman-filter-based powerful data fusion, which also allows the estimation and correction of parameters that are typically affected by sensor aging, especially when applying MEMS-based inertial sensors, and which is not yet deeply considered in the literature...
April 26, 2017: Sensors
https://www.readbyqxmd.com/read/28445414/platform-architecture-for-decentralized-positioning-systems
#7
Zakaria Kasmi, Abdelmoumen Norrdine, Jörg Blankenbach
A platform architecture for positioning systems is essential for the realization of a flexible localization system, which interacts with other systems and supports various positioning technologies and algorithms. The decentralized processing of a position enables pushing the application-level knowledge into a mobile station and avoids the communication with a central unit such as a server or a base station. In addition, the calculation of the position on low-cost and resource-constrained devices presents a challenge due to the limited computing, storage capacity, as well as power supply...
April 26, 2017: Sensors
https://www.readbyqxmd.com/read/28445410/c-c-coupling-reactions-between-benzofurazan-derivatives-and-1-3-diaminobenzenes
#8
Gabriele Micheletti, Silvia Bordoni, Elena Chugunova, Carla Boga
Aromatic substitution reactions between 1,3-diaminobenzene and chloronitrobenzofurazan derivatives have never been reported so far. The aim of the current study was to synthesize novel electron-donor and -acceptor architectures of interest in applied fields and to provide new insights on the nucleophilic behavior of 1,3-diaminobenzenes. The reaction of 1,3-dipiperidinyl-, 1,3-dimorpholinyl-, 1,3-dipyrrolidinyl-, or 1,3-dimethylamino-benzene with 7-chloro-4,6-dinitrobenzofuroxan or with a series of chloro-nitrobenzofurazans has been carried out in mild conditions...
April 26, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28445203/considerations-for-refractive-surgery-in-the-glaucoma-patient
#9
Meleha Ahmad, Isaac Chocron, Anurag Shrivastava
PURPOSE OF REVIEW: Given the popularity of keratorefractive surgery, and an aging populous of patients who have undergone these procedures, there is an increasing need for updated management protocols. This is particularly relevant for patients with chronic progressive diseases such as glaucoma, due to the variety of related diagnostic and management challenges inherent to these diseases. Here, we will review the current literature to provide an update on the management of patients with glaucoma who are undergoing, or have had laser ablative refractive surgery...
April 25, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28445032/super-stretchable-nacre-mimetic-graphene-poly-vinyl-alcohol-composite-film-based-on-interfacial-architectural-engineering
#10
Nifang Zhao, Miao Yang, Qian Zhao, Weiwei Gao, Tao Xie, Hao Bai
Through designing hierarchical structures, particularly optimizing the chemical and architectural interactions at its inorganic/organic interface, nacre has achieved an excellent combination of contradictory mechanical properties such as strength and toughness, which is highly demanded yet difficult to achieve by most synthetic materials. Most techniques applied to develop nacre-mimetic composites have been focused on mimicking the 'brick-and-mortar' structure, but the interfacial architectural features, especially the asperities and mineral bridges of 'bricks', have been rarely concerned, which are of equal importance for enhancing mechanical properties of nacre...
April 26, 2017: ACS Nano
https://www.readbyqxmd.com/read/28444937/soluble-inorganic-nanoparticle-constructed-porous-coordination-frameworks-as-homogenized-heterogeneous-photocatalysts-for-suzuki-coupling-reaction-under-near-infrared-light
#11
Baodui Wang, Yuting Luo, Yong Peng, Weisheng Liu, Fengjuan Chen
Self-assembly has emerged as a promising method to control the structure and properties of ensembles of inorganic nanoparticles (NPs) for exploiting their collective effects. However, the rational assembly of inorganic NPs into soluble porous architectures as homogenized heterogeneous catalyst has been less studied. Here, we show that inorganic NPs can be used for the assembly of soluble porous coordination frameworks (PCFs) by atom-scale interfacial coordination-driven assembly strategy. Given large pore size, high dispersity in solution, strong absorption in the near-infrared range (NIR), and a long living electron-hole pair, the obtained soluble framework can serve as a platform for homogenize heterogeneous photocatalysts, which exhibited excellent activity, high apparent quantum efficiency, and recyclability to catalyze the noble metal free Suzuki coupling reaction under NIR light at room temperature...
April 26, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28444767/the-dual-orexin-receptor-antagonist-dora-22-lowers-histamine-levels-in-the-lateral-hypothalamus-and-prefrontal-cortex-without-lowering-hippocampal-acetylcholine
#12
Lihang Leon Yao, Andres Ramirez, Anthony J Roecker, Steven Fox, Jason Uslaner, Sean M Smith, Robert Hodgson, Paul J Coleman, John J Renger, Christopher J Winrow, Anthony L Gotter
Chronic insomnia is defined as a persistent difficulty with sleep initiation maintenance or non-restorative sleep. The therapeutic standard of care for this condition is treatment with gamma-aminobutyric acid (GABA)A receptor modulators, which promote sleep but are associated with a panoply of side effects, including cognitive and memory impairment. Dual orexin receptor antagonists (DORAs) have recently emerged as an alternative therapeutic approach that acts via a distinct and more selective wake-attenuating mechanism with the potential to be associated with milder side effects...
April 26, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28444433/boundaries-of-the-thoracic-paravertebral-space-potential-risks-and-benefits-of-the-thoracic-paravertebral-block-from-an-anatomical-perspective
#13
Esther A C Bouman, Judith M Sieben, Andrea J R Balthasar, Elbert A Joosten, Hans-Fritz Gramke, Maarten van Kleef, Arno Lataster
PURPOSE: Thoracic paravertebral block (TPVB) may be an alternative to thoracic epidural analgesia. A detailed knowledge of the anatomy of the TPV-space (TPVS), content and adnexa is essential in understanding the clinical consequences of TPVB. The exploration of the posterior TPVS accessibility in this study allows (1) determination of the anatomical boundaries, content and adnexa, (2) description of an ultrasound-guided spread of low and high viscous liquid. METHODS: In two formalin-fixed specimens, stratification of the several layers and the 3D-architecture of the TPVS were dissected, observed and photographed...
April 25, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28444144/congenital-zika-virus-infection-induces-severe-spinal-cord-injury
#14
Fernando S Ramalho, Aparecida Y Yamamoto, Luis L da Silva, Luiz Tm Figueiredo, Lenaldo B Rocha, Luciano Neder, Sara R Teixeira, Letícia A Apolinário, Leandra Nz Ramalho, Deisy M Silva, Conrado M Coutinho, Patrícia P Melli, Marlei J Augusto, Ligia B Santoro, Geraldo Duarte, Marisa M Mussi-Pinhata
We reported two fatal cases of congenital Zika virus (ZIKV) infection. Brain anomalies including atrophy of the cerebral cortex and brainstem, and cerebellar aplasia were observed. The spinal cord showed architectural distortion, severe neuronal loss and microcalcifications. The ZIKV proteins and flavivirus-like particles were detected in cytoplasm of spinal neurons, and spinal cord samples were positive for the ZIKV RNA.
April 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444127/hla-class-i-binding-prediction-via-convolutional-neural-networks
#15
Yeeleng S Vang, Xiaohui Xie
Motivation: Many biological processes are governed by protein-ligand interactions. One such example is the recognition of self and nonself cells by the immune system. This immune response process is regulated by the major histocompatibility complex (MHC) protein which is encoded by the human leukocyte antigen (HLA) complex. Understanding the binding potential between MHC and peptides can lead to the design of more potent, peptide-based vaccines and immunotherapies for infectious autoimmune diseases...
April 21, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28443904/na3v2-po4-3-nitrogen-sulfur-codoped-3d-porous-carbon-enabling-ultra-long-cycle-life-sodium-ion-batteries
#16
Yu Jiang, Haochuan Zhang, Hai Yang, Zhenyu Qi, Yan Yu
Na3V2(PO4)3 (NVP) is regarded as a promising cathode material for sodium ion batteries (NIBs) because of its 3D open structure suitable for Na insertion/extraction and high energy density. However, the NVP suffers from poor electrical conductivity, which restricts the rate performance and the long cycle performance of the NVP for NIBs. Here, the NVP particles embedded in the N,S co-doped 3D porous carbon matrix (denoted as NVP@3D-NSC) were prepared by a facile process. The NVP@3D-NSC can deliver high specific discharge capacities at high rates (54 mA h g(-1) at 80 C)...
April 26, 2017: Nanoscale
https://www.readbyqxmd.com/read/28443654/quantifying-the-self-assembly-behavior-of-anisotropic-nanoparticles-using-liquid-phase-transmission-electron-microscopy
#17
Binbin Luo, John W Smith, Zihao Ou, Qian Chen
For decades, one of the overarching objectives of self-assembly science has been to define the rules necessary to build functional, artificial materials with rich and adaptive phase behavior from the bottom-up. To this end, the computational and experimental efforts of chemists, physicists, materials scientists, and biologists alike have built a body of knowledge that spans both disciplines and length scales. Indeed, today control of self-assembly is extending even to supramolecular and molecular levels, where crystal engineering and design of porous materials are becoming exciting areas of exploration...
April 26, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28443589/significance-of-inverted-pattern-in-non-invasive-low-grade-papillary-urothelial-carcinoma-of-bladder
#18
Sehbal Arslankoz, İbrahim Kulaç, Dilek Ertoy Baydar
AIMS: The purpose of this study is to evaluate the impact of histological inverted pattern on recurrence in patients with newly diagnosed non-invasive low-grade papillary urothelial carcinoma of the urinary bladder. METHODS: A total of 81 patients with primary bladder non-invasive low-grade papillary urothelial carcinomadiagnosed in a single tertiary care center between 2000 and 2011 who had at least 1 year follow-up after an initial resection were included. All slides from each case were reviewed to determine the growth pattern (exophytic versus endophytic, i...
April 13, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28443507/synthesis-and-biological-activity-of-unnatural-enediynes
#19
Roberto Romeo, Salvatore V Giofrè, Maria A Chiacchio
The first reports of the natural enediyne anticancer antibiotics date back to the late 1980s; since then, a great deal of interest has been devoted to the chemistry, biology and potential medical applications of this family of compounds. The biological activity of enediynes is linked to the presence of a highly unsaturated hex-1-ene- 1,5-diyne system. The thermally induced transformation of this unit into a benzene  diradical (the Bergman cycloaromatization) is the key step of the antitumor properties of such compounds: 1,4-diaryl radicals are able to abstract H-atoms from the deoxyribose backbone of DNA, thus leading to DNA strand cleavage and ultimately cell death...
April 24, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28443296/data-of-sperm-entry-inability-in-drosophila-melanogaster-ovarian-follicles-that-are-depleted-of-s36-chorionic-protein
#20
Athanassios D Velentzas, Panagiotis D Velentzas, Stamatia Katarachia, Vassiliki E Mpakou, Issidora S Papassideri, Dimitrios J Stravopodis
This paper presents data associated with the research article entitled "Targeted downregulation of s36 protein unearths its cardinal role in chorion biogenesis and architecture during Drosophila melanogaster oogenesis" [1]. Drosophila chorion is produced by epithelial follicle cells and one of its functional serving role is egg fertilization through the micropyle, a specialized narrow channel at the anterior tip of the egg [2]. Sperm entry during fertilization is necessary for the egg to complete meiosis [3]...
June 2017: Data in Brief
keyword
keyword
14228
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"