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serpiginous choroiditis

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https://www.readbyqxmd.com/read/29117661/a-rare-case-of-infectious-multifocal-serpiginoid-choroiditis
#1
Miloš Mitrašević, Svetlana Jovanović, Filip Radotić, Snežana Pešić, Zorica Jovanović
Multifocal serpiginoid choroiditis is an infectious variety of serpiginous choroiditis. The disease is characterized by infectious etiology and overlapping clinical features in an intermediary form of acute posterior multifocal placoid pigment epitheliopathy and serpiginous choroiditis. In a 33-year-old patient, bilateral multiple placoid partially confluent chorioretinal lesions were diagnosed after a febrile flu-like episode. On the right eye, there was a progressive decrease in visual acuity. Later, the lesions had a prolonged progressive devastating clinical course and widespread distribution of placoid lesions, and took the form of serpiginoid choroiditis...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/28982952/swept-source-optical-coherence-tomography-angiography-in-serpiginous-choroiditis
#2
Daniela Montorio, Chiara Giuffrè, Elisabetta Miserocchi, Giulio Modorati, Riccardo Sacconi, Stefano Mercuri, Lea Querques, Giuseppe Querques, Francesco Bandello
BACKGROUND/AIMS: To analyse choroidal vascular density of affected and non-affected areas in active and inactive serpiginouschoroiditis (SC) by means of optical coherence tomography angiography (OCT-A). METHODS: In this cross-sectional and observational study, 22 eyes of 11 patients diagnosed with SC were included. All patients underwent blue-light fundus autofluorescence (spectralis Heidelberg retinalangiography+OCT) and swept-source OCT-A (AngioPlex Elite 9000 SS-OCT, Carl Zeiss Meditech) to analyse qualitative features and choroidal vessel density of areas considered affected, and the inner and the outer border of the lesions...
October 5, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28965349/forme-fruste-focal-choroidal-excavation-in-a-case-of-serpiginous-choroiditis
#3
Rupak Roy, Kumar Saurabh, Chinmayi Vyas, Preeti Sharma, Aditya Bansal
No abstract text is available yet for this article.
October 1, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28960121/multimodal-evaluation-of-patients-with-acute-posterior-multifocal-placoid-pigment-epitheliopathy-and-serpiginous-choroiditis
#4
Monique Mangeon, Claudio Zett, Camila Amaral, Eduardo Novais, Cristina Muccioli, Gabriel Andrade, Heloisa Nascimento, Rubens Belfort
PURPOSE: To evaluate retinal and choroidal changes in patients with non-granulomatous choroiditis using the multimodality imaging (MMI). METHODS: Eight eyes of four patients were analyzed. Three patients (six eyes) were diagnosed with serpiginous choroiditis (SC) and one patient (two eyes) with acute posterior multifocal placoid pigment epitheliopathy (APMPPE). The patients were imaged on the same day using the RTVue Avanti XR instrument OCT/OCTA (Optovue Inc, Fremont, CA), Heidelberg Retina Angiograph 2 FAF and FA (Heidelberg Engineering, Germany), and TRC50DXi Topcon FP (Topcon Medical Systems, Oakland, NJ)...
September 29, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28901810/the-incidence-of-ocular-tuberculosis-in-australia-over-the-past-10-years-2006-2015
#5
Erica Darian-Smith, Ming-Lee Lin, Lyndell L Lim, Peter McCluskey, Anthony J Hall
PURPOSE: To determine the incidence and clinical phenotype of ocular tuberculosis in Australia based on the mandatory jurisdictional health notification records for TB. METHODS: A whole population retrospective case series (Australia). Patients diagnosed with ocular tuberculosis were identified over the past 10 years (1 January 2006 to 31 December 2015) as recorded by individual Health Department jurisdictions per mandatory health notifications. The incidence rates were calculated based on the available Australian census data...
September 13, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28820170/paradoxical-worsening-of-a-case-of-tb-subretinal-abscess-with-serpiginous-like-choroiditis-following-the-initiation-of-antitubercular-therapy
#6
Sudha K Ganesh, B Sowkath Ali
A 37-year-old immunocompetent male patient presented with the blurring of vision, both eyes for the past1 year. Fundus examination revealed bilateral multiple subretinal abscesses with areas of healed serpiginous-like choroiditis. Laboratory investigations showed positive tuberculin skin test, positive QuantiFERON TB-Gold Test, and high resolution computed tomography chest showed enlarged mediastinal lymph nodes. The aqueous sample revealed polymerase chain reaction (PCR) positive for Mycobacterium tuberculosis (MTB) (MPB64 genome)...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28776591/presumed-tuberculosis-associated-uveitis-rising-incidence-and-widening-criteria-for-diagnosis-in-a-non-endemic-area
#7
N Krassas, J Wells, C Bell, M Woodhead, N Jones
PurposeTo assess the incidence, clinical ocular involvement and effectiveness of anti-tuberculous treatment in patients with chronic uveitis presumed to be associated with tuberculosis in a non-endemic community.Patients and methodsRetrospective case series of patients with uveitis and evidence of tuberculosis, with no other identified cause of uveitis, who underwent a 6-month course of standard anti-tuberculosis treatment between 2008 and 2015. The response to treatment was assessed at 6 and 12 months after initiation of treatment...
August 4, 2017: Eye
https://www.readbyqxmd.com/read/28418567/serpiginous-choroiditis
#8
Aseef H Ahmed, Buraa Kubaisi, C Stephen Foster
No abstract text is available yet for this article.
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28405483/treatment-results-in-serpiginous-choroiditis-and-multifocal-serpiginoid-choroiditis-associated-with-latent-tuberculosis
#9
Merih Oray, Zaur Zakiev, Tülin Çağatay, İlknur Tuğal-Tutkun
OBJECTIVES: To compare the results of systemic antitubercular therapy (ATT) and immunomodulatory therapy (IMT) in patients with serpiginous choroiditis (SC) or multifocal serpiginoid choroiditis (MSC). MATERIALS AND METHODS: The clinical records of 28 patients with SC and MSC were reviewed. Patients were divided into 2 groups according to the treatment applied. Group 1 included 12 patients with MSC and 5 with SC treated with ATT and corticosteroid (CS); group 2 included 9 patients with MSC and 2 with SC treated with conventional IMT, interferon alpha-2a, and/or CS monotherapy...
April 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28281863/multimodal-imaging-including-optical-coherence-tomography-angiography-in-serpiginous-choroiditis
#10
Seong Joon Ahn, Seung Hoon Park, Byung Ro Lee
PURPOSE: To report multimodal imaging in patients with serpiginous choroiditis. METHODS: A 60-year-old woman with active serpiginous choroiditis in the right eye was evaluated during the disease course with multimodal imaging, which included fluorescein angiography, swept-source optical coherence tomography (SS-OCT), OCT angiography, fundus autofluorescence (FAF), and retromode imaging. RESULTS: The patient had subretinal, yellowish lesion on the macula at presentation...
April 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28253223/observation-and-clinical-pattern-in-patients-with-white-dot-syndromes-the-role-of-color-photography-in-monitoring-ocular-changes-in-long-term-observation
#11
Joanna Brydak-Godowska, Joanna Gołębiewska, Monika Turczyńska, Joanna Moneta-Wielgoś, Agnieszka Samsel, Piotr K Borkowski, Michał Ciszek, Agnieszka Płonecka-Rodzoch, Aleksandra Kużnik-Borkowska, Joanna Ciszewska, Elżbieta Makomaska-Szaroszyk, Lidia B Brydak, Dariusz Kęcik
BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with observation period ranging from 5 months to 16 years. All patients underwent a complete ophthalmological examination and multimodal imaging studies...
March 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28112131/polymerase-chain-reaction-for-mycobacterium-tuberculosis-dna-detection-from-ocular-fluids-in-patients-with-various-types-of-choroiditis-in-a-referral-eye-center-in-india
#12
Jyotirmay Biswas, Mohmmad Salman Kazi, Vishvesh Ashokkumar Agarwal, Md Shahid Alam, K Lily Therese
AIMS: The aim of this study was to detect Mycobacterium tuberculosis (MTB) DNA with polymerase chain reaction (PCR) in aqueous or vitreous samples of patients suffering from choroiditis presumed to be infectious origin. SETTINGS AND DESIGN: Hospital-based, retrospective case-control study. SUBJECTS AND METHODS: In all, forty eyes of forty patients with choroiditis divided into two groups - Group A (serpiginous-like choroiditis, ampiginous choroiditis, multifocal choroiditis) and Group B (choroidal abscess, miliary tuberculosis (TB), choroidal tubercle) were analyzed retrospectively...
December 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058156/paradoxical-worsening-of-tubercular-serpiginous-like-choroiditis-after-initiation-of-antitubercular-therapy
#13
Ebru Esen, Selçuk Sızmaz, Zeynep Kunt, Nihal Demircan
In this study, a case with tubercular choroiditis showing severe macular edema and progression of choroidal lesions following initiation of antitubercular treatment is presented and the management of posterior uveitis associated with tuberculosis is evaluated. A 40-year-old female patient was admitted with decreased vision in her right eye and her fundoscopic examination revealed serpiginous choroiditis. It was learned from her medical history that she had taken antitubercular therapy 9 years ago. Mantoux tuberculin skin test showed an area of induration measuring 15 mm and a positive interferon-gamma release assay was documented...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28033230/serpiginous-choroiditis-imaged-by-optical-coherence-tomography-angiography
#14
Alaʼa El Ameen, Carl P Herbort
PURPOSE: To report a case of serpiginous choroiditis imaged with optical coherence tomography angiography (OCT-A). METHODS: Case report. RESULTS: Multimodal imaging and OCT-A were performed to investigate serpiginous choroiditis in a 65-year-old patient. Comparison between OCT-A images and intermediate and late phase indocyanine green angiography revealed that the hypofluorescent areas on indocyanine green angiography corresponded topographically to the dark areas seen in the choriocapillaris layer of OCT-A...
December 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27930457/novel-findings-on-optical-coherence-tomography-angiography-in-patients-with-tubercular-serpiginous-like-choroiditis
#15
Spoorti Krishna Reddy Mandadi, Aniruddha Agarwal, Kanika Aggarwal, Bruttendu Moharana, Ramandeep Singh, Aman Sharma, Reema Bansal, Mangat R Dogra, Vishali Gupta
PURPOSE: To analyze and describe the imaging characteristics of tubercular serpiginous-like choroiditis using optical coherence tomography angiography (OCTA) and to compare these findings with multimodal imaging. METHODS: In this prospective cross-sectional study, multimodal imaging was performed in subjects with tubercular serpiginous-like choroiditis using OCTA (Optovue RTVue XR Avanti), enhanced-depth imaging OCT (Heidelberg Spectralis), fundus autofluorescence, fluorescein angiography, and indocyanine green angiography...
September 2017: Retina
https://www.readbyqxmd.com/read/27853021/efficacy-of-reduced-dose-of-intravitreal-triamcinolone-acetonide-in-a-case-of-active-serpiginous-choroiditis
#16
Avirupa Ghose, Promod S Bhende, Jyotirmoy Biswas
Active serpiginous choroiditis (SC) is a vision-threatening condition which requires intensive treatment using corticosteroids and/or immunosuppressives, especially if the lesions are involving or encroaching on the macula. Use of oral and intravenous high-dose steroids are contraindicated in uncontrolled diabetics. Intravitreal steroid delivers a localized dose in such situations. This case report highlights the efficacy of reduced dose of intravitreal triamcinolone acetonide (2 mg) in the treatment of active SC...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27849419/short-term-intensive-immunosuppression-a-randomized-three-arm-study-of-intravenous-pulse-methylprednisolone-and-cyclophosphamide-in-macular-serpiginous-choroiditis
#17
Pradeep Venkatesh, Akshay Tayade, Varun Gogia, Shikha Gupta, Bhavin M Shah, Rajpal Vohra
PURPOSE: To compare the efficacy of pulse cyclophosphamide with pulse dexamethasone in acute macular serpiginous choroiditis (SC). METHODS: A total of 30 patients with macular SC were prospectively randomized into three treatment groups: group D (pulse dexamethasone); group C (pulse cyclophosphamide); and combination (pulse group DCP) administered for 3 days. Macular SC was defined as any active lesion involving/threatening macula. RESULTS: A total of 30 patients were enrolled, with 10 patients in each group...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27779556/multimodal-imaging-of-serpiginous-choroiditis
#18
Hashim Ali Khan, Muhammad Aamir Shahzad
PURPOSE: To report a case of atypical serpiginous choroiditis with previously unreported findings on optical coherence tomographic angiography. CASE REPORT: A 35-year-old otherwise healthy man had a 1-week history of vision loss in his right eye. The visual acuity in right eye was counting fingers at 1 meter. Fundoscopy showed a classic peripapillary serpiginous lesion and a solitary macular lesion. Fundus fluorescein angiography revealed early hypofluorescence of active lesions with gradual increase in fluorescence across the phase of angiogram...
February 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27754769/treatment-of-serpiginous-choroiditis-with-chlorambucil-a-report-of-17-patients
#19
Nazanin Ebrahimiadib, Bobeck S Modjtahedi, Samaneh Davoudi, C Stephen Foster
PURPOSE: To evaluate the efficacy of chlorambucil in the treatment of serpiginous choroiditis. METHODS: Patient records from the Massachusetts Eye Research and Surgery Institution (MERSI) were reviewed from over the past 10 years. In total, 17 patients with the diagnosis of serpiginous choroiditis treated with chlorambucil were identified. QuantiFERON gold was negative in all of them. Chlorambucil was started at 0.15 mg/kg and dosage was titrated up using weekly white blood cell (WBC) count to achieve a target cell number of 3...
October 18, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27256717/dexamethasone-intravitreal-implant-in-serpiginous-choroiditis
#20
Elisabetta Miserocchi, Luigi Berchicci, Lorenzo Iuliano, Giulio Modorati, Francesco Bandello
BACKGROUND/AIMS: To assess the efficacy and safety of dexamethasone (DEX) intravitreal implant in patients with active serpiginous choroiditis (SC) already receiving maximal tolerated systemic immunosuppressive therapy. METHODS: In this retrospective longitudinal study we evaluated patients receiving 0.7 mg DEX intravitreal implant for active SC despite maximal systemic immunosuppression. Medical history was reviewed over a period of 18 months for each patient...
March 2017: British Journal of Ophthalmology
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