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https://www.readbyqxmd.com/read/28731029/nrp2-is-sufficient-to-instruct-circuit-formation-of-mitral-cells-to-mediate-odour-induced-attractive-social-responses
#1
Kasumi Inokuchi, Fumiaki Imamura, Haruki Takeuchi, Ryang Kim, Hiroyuki Okuno, Hirofumi Nishizumi, Haruhiko Bito, Takefumi Kikusui, Hitoshi Sakano
Odour information induces various innate responses that are critical to the survival of the individual and for the species. An axon guidance molecule, Neuropilin 2 (Nrp2), is known to mediate targeting of olfactory sensory neurons (primary neurons), to the posteroventral main olfactory bulb (PV MOB) in mice. Here we report that Nrp2-positive (Nrp2(+)) mitral cells (MCs, second-order neurons) play crucial roles in transmitting attractive social signals from the PV MOB to the anterior part of medial amygdala (MeA)...
July 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28728998/sialylation-of-igg-antibodies-inhibits-igg-mediated-allergic-reactions
#2
Alexandra Epp, Juliane Hobusch, Yannic C Bartsch, Janina Petry, Gina-Maria Lilienthal, Carolien A M Koeleman, Simon Eschweiler, Christian Möbs, Ashley Hall, Suzanne C Morris, Dominique Braumann, Christine Engellenner, Josephine Bitterling, Johann Rahmöller, Alexei Leliavski, Robina Thurmann, Mattias Collin, Kelley W Moremen, Richard T Strait, Véronique Blanchard, Arnd Petersen, Timo Gemoll, Jens K Habermann, Frank Petersen, Andreas Nandy, Helga Kahlert, Michael Hertl, Manfred Wuhrer, Wolfgang Pfützner, Uta Jappe, Fred D Finkelman, Marc Ehlers
In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.
July 17, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28724776/inhibitory-circuits-of-the-mammalian-main-olfactory-bulb
#3
Shawn D Burton
Synaptic inhibition critically influences sensory processing throughout the mammalian brain, including the main olfactory bulb (MOB), the first station of sensory processing in the olfactory system. Decades of research across numerous laboratories have established a central role for granule cells (GCs), the most abundant GABAergic interneuron type in the MOB, in the precise regulation of principal mitral and tufted cell (M/TC) firing rates and synchrony through lateral and recurrent inhibitory mechanisms. In addition to GCs, however, the MOB contains a vast diversity of other GABAergic interneuron types, and recent findings suggest that, while fewer in number, these oft-ignored interneurons are just as important as GCs in shaping odor-evoked M/TC activity...
July 19, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28702724/acoustic-structure-of-alarm-calls-in-indian-sambar-rusa-unicolor-and-indian-muntjac-muntiacus-vaginalis-in-south-vietnam
#4
I A Volodin, E V Volodina, R Frey, S S Gogoleva, I V Palko, V V Rozhnov
The alarm call acoustic structure and nonlinear vocal phenomena of the Indian sambar (Rusa unicolor) and northern Indian muntjac (Muntiacus vaginalis) have been analyzed in detail as well as their vocal behavior in response to mobbing humans under natural conditions of southern Vietnam. The alarm calls of sambars, tonal barks separated by large intervals, were produced by animals standing on the place and gazing at a potentially dangerous object. Muntjacs flee off in danger and produced a series of dull barks interrupted with short intervals from a distance...
May 2017: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/28701085/book-review-misbehavior-in-organizations-a-dynamic-approach-cyberbullying-where-are-we-now-a-cross-national-understanding-infostorms-why-do-we-like-explaining-individual-behavior-on-the-social-net-stalker-hacker-voyeur-spy-a-psychoanalytic-study-of-erotomania
#5
Martin Guha
No abstract text is available yet for this article.
August 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28687652/high-temporal-and-spatial-variability-of-atmospheric-methane-oxidation-in-alpine-glacier-forefield-soils
#6
Eleonora Chiri, Philipp A Nauer, Edda-Marie Rainer, Josef Zeyer, Martin H Schroth
Glacier-forefield soils can provide a substantial sink for atmospheric CH4, facilitated by aerobic methane-oxidizing bacteria (MOB). However, MOB activity, abundance, and community structure may be affected by soil age, location in different forefield landforms, and temporal fluctuations in soil-physical parameters. We assessed spatial and temporal variability of atmospheric CH4 oxidation in an Alpine glacier forefield during the snow-free season 2013. We quantified CH4 flux in soils of increasing age and in different landforms (sandhill, terrace, floodplain) using soil-gas-profile and static flux-chamber methods...
July 7, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28646182/high-intensity-interval-training-improves-mitochondrial-function-and-suppresses-thrombin-generation-in-platelets-undergoing-hypoxic-stress
#7
Li-Hua Wu, Shao-Chiang Chang, Tieh-Cheng Fu, Ching-Hui Huang, Jong-Shyan Wang
This study elucidates how high-intensity interval training (HIT) and moderate-intensity continuous training (MCT) affect mitochondrial functionality and thrombin generation (TG) in platelets following hypoxic exercise (HE, 100 W under 12% O2 for 30 min). Forty-five healthy sedentary males were randomized to engage either HIT (3-minute intervals at 40% and 80%VO2max, n = 15) or MCT (sustained 60%VO2max, n = 15) for 30 minutes/day, 5 days/week for 6 weeks, or to a control group (CTL, n = 15) that did not received exercise intervention...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28636868/deadly-liver-mob-opening-the-door-improving-sexual-health-pathways-for-aboriginal-people-in-western-sydney
#8
Karen Biggs, Jennifer Walsh, Catriona Ooi
BACKGROUND: The Deadly Liver Mob project (DLM) is an incentive-based, peer-driven health promotion intervention for Aboriginal people, focusing on hepatitis C and offering education and screening for sexually transmissible infections (STI) and blood-borne viruses (BBV). This study aims to assess the DLM effect on attendance and STI/BBV screening, describe BBV risk factors and report infection rates among Aboriginal people attending Western Sydney Sexual Health Centre (WSSHC). METHODS: A retrospective review of Aboriginal clients during the first year of the DLM project was compared with Aboriginal clients who attended during the 5...
October 2016: Sexual Health
https://www.readbyqxmd.com/read/28593095/load-enhanced-movement-quality-screening-and-tactical-athleticism-an-extension-of-evidence
#9
Stephen M Glass, Randy J Schmitz, Christopher K Rhea, Scott E Ross
BACKGROUND: Military organizations use movement quality screening for prediction of injury risk and performance potential. Currently, evidence of an association between movement quality and performance is limited. Recent work has demonstrated that external loading strengthens the relationship between movement screens and performance outcomes. Such loading may therefore steer us toward robust implementations of movement quality screens while maintaining their appeal as cost effective, field-expedient tools...
June 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28585360/functional-and-phenotypic-analysis-of-basophils-allows-determining-distinct-subtypes-in-patients-with-chronic-urticaria
#10
M M Rauber, J Pickert, L Holiangu, C Möbs, W Pfützner
BACKGROUND: Chronic urticaria (CU) is a frequent skin disease characterized by relapsing appearance of pruritic hives. While clinical symptoms are due to the release of histamine by cutaneous mast cells, the underlying pathophysiology is still unknown. However, previous studies indicate that basophils might be of relevance. Besides, the occurrence of autoantibodies against IgE or its receptor, FcεRI, and the therapeutic efficacy of anti-IgE antibodies imply that IgE-mediated mechanisms also play an important role in CU...
June 5, 2017: Allergy
https://www.readbyqxmd.com/read/28560890/book-review-misbehavior-in-organizations-a-dynamic-approach-cyberbullying-where-are-we-now-a-cross-national-understanding-infostorms-why-do-we-like-explaining-individual-behavior-on-the-social-net-stalker-hacker-voyeur-spy-a-psychoanalytic-study-of-erotomania
#11
Martin Guha
No abstract text is available yet for this article.
May 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28554256/integration-of-methane-removal-in-aerobic-anammox-based-granular-sludge-reactors
#12
Celia M Castro-Barros, Long T Ho, Mari K H Winkler, Eveline I P Volcke
Combined partial nitritation-anaerobic ammonium oxidation (anammox) processes have been widely applied for nitrogen removal from anaerobic digestion reject water. However, such streams also contain dissolved methane that can escape to the atmosphere, hence contributing to global warming. This study investigates the possibility of integrating methane removal in aerobic anammox-based granular sludge reactors, through modelling and simulation. Methane removal could be established through aerobic methane-oxidizing bacteria (MOB), denitrifying anaerobic methane-oxidizing bacteria (damoB, NO2(-) + CH4à N2 + CO2), and/or archaea (damoA, NO3(-) + CH4à NO2(-) + CO2)...
June 8, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28522884/profiles-of-periglomerular-cells-in-the-olfactory-bulb-of-prokineticin-type-2-receptor-deficient-mice
#13
Atsuko Kubo, Mitsugu Sujino, Koh-Hei Masumoto, Atsuko Fujioka, Toshio Terashima, Yasufumi Shigeyoshi, Mamoru Nagano
Both prokineticin receptor 2 (pkr2) and prokineticin 2 (pk2) gene-deficient mice have hypoplasia of the main olfactory bulb (MOB). This hypoplasia has been attributed to disruption of the glomerulus that is caused by loss of afferent projection from olfactory sensory neurons (OSN), and to the impaired migration of granule cells, a type of interneuron. In the present study, we examined whether migration of the second type of interneuron, periglomerular cells (PGC), is dependent on the pkr2 expression by observing the localization of distinct subpopulations of PGC: calretinin (CR)-, calbindin (CB)- and tyrosine hydroxylase (TH)-expressing neurons...
April 27, 2017: Acta Histochemica et Cytochemica
https://www.readbyqxmd.com/read/28516137/a-curated-dataset-of-complete-enterobacteriaceae-plasmids-compiled-from-the-ncbi-nucleotide-database
#14
Alex Orlek, Hang Phan, Anna E Sheppard, Michel Doumith, Matthew Ellington, Tim Peto, Derrick Crook, A Sarah Walker, Neil Woodford, Muna F Anjum, Nicole Stoesser
Thousands of plasmid sequences are now publicly available in the NCBI nucleotide database, but they are not reliably annotated to distinguish complete plasmids from plasmid fragments, such as gene or contig sequences; therefore, retrieving complete plasmids for downstream analyses is challenging. Here we present a curated dataset of complete bacterial plasmids from the clinically relevant Enterobacteriaceae family. The dataset was compiled from the NCBI nucleotide database using curation steps designed to exclude incomplete plasmid sequences, and chromosomal sequences misannotated as plasmids...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28512362/-copenhagen-psychosocial-questionnaire-copsoq-psychometric-properties-of-selected-scales-in-the-polish-version
#15
Maria Widerszal-Bazyl
BACKGROUND: The Copenhagen Psychosocial Questionniare (COPSOQ) has many advantages as compared to other similar instruments, i.a., it is not related to one single theoretical model and it measures a wide spectrum of psychosocial working conditions that have shown proven impact on health. The aim of the article is to summarize information on psychometric properties of 11 scales in the Polish version: Quantitative Demands, Emotional Demands, Influence at Work, Social Support, Possibilities for Development, Meaning of Work, Role Clarity, Quality of Leadership, Job Insecurity, Job Satisfaction, and General Health...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28496397/conflicts-at-work-are-associated-with-a-higher-risk-of-cardiovascular-disease
#16
Louis Jacob, Karel Kostev
Background: Only few authors have analyzed the impact of workplace conflicts and the resulting stress on the risk of developing cardiovascular disorders. The goal of this study was to analyze the association between workplace conflicts and cardiovascular disorders in patients treated by German general practitioners. Methods: Patients with an initial documentation of a workplace conflict experience between 2005 and 2014 were identified in 699 general practitioner practices (index date). We included only those who were between the ages of 18 and 65 years, had a follow-up time of at least 180 days after the index date, and had not been diagnosed with angina pectoris, myocardial infarction, coronary heart diseases, or stroke prior to the documentation of the workplace mobbing...
2017: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/28487684/relative-abundance-and-diversity-of-bacterial-methanotrophs-at-the-oxic-anoxic-interface-of-the-congo-deep-sea-fan
#17
Sandrine Bessette, Yann Moalic, Sébastien Gautey, Françoise Lesongeur, Anne Godfroy, Laurent Toffin
Sitting at ∼5,000 m water depth on the Congo-Angola margin and ∼760 km offshore of the West African coast, the recent lobe complex of the Congo deep-sea fan receives large amounts of fluvial sediments (3-5% organic carbon). This organic-rich sedimentation area harbors habitats with chemosynthetic communities similar to those of cold seeps. In this study, we investigated relative abundance, diversity and distribution of aerobic methane-oxidizing bacteria (MOB) communities at the oxic-anoxic interface of sedimentary habitats by using fluorescence in situ hybridization and comparative sequence analysis of particulate mono-oxygenase (pmoA) genes...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28435006/horizontal-transfer-of-chromosomal-markers-mediated-by-the-large-conjugative-plasmid-pxo16-from-bacillus-thuringiensis-serovar-israelensis
#18
Lionel Makart, Florian Commans, Annika Gillis, Jacques Mahillon
pXO16, a large plasmid originating from Bacillus thuringiensis serovar israelensis, displays unique conjugation capacities: besides efficient self-transfer, it is able to mobilize and retro-mobilize non-conjugative plasmids, including those missing an oriT and/or a mob gene, also known as "non-mobilizable" plasmids. In this paper, another peculiar transfer property of pXO16 is described. This element is indeed able to transfer chromosomal loci at frequencies of ca. 10(-5)-10(-6) transconjugants/donor cell. Whereas most other chromosomal transfer systems occur via the integration of the conjugative elements into the chromosome prior to its transfer, pXO16 appears to transfer the chromosomal markers in the absence of physical integration, but rather through a "donation-type" mobilization...
April 20, 2017: Plasmid
https://www.readbyqxmd.com/read/28411218/the-conjugative-relaxase-trwc-promotes-integration-of-foreign-dna-in-the-human-genome
#19
Coral González-Prieto, Richard Gabriel, Christoph Dehio, Manfred Schmidt, Matxalen Llosa
Bacterial conjugation is a mechanism of horizontal DNA transfer. The relaxase TrwC of the conjugative plasmid R388 cleaves one strand of the transferred DNA at the oriT gene, covalently attaches to it, and leads the single-stranded DNA (ssDNA) into the recipient cell. In addition, TrwC catalyzes site-specific integration of the transferred DNA into its target sequence present in the genome of the recipient bacterium. Here, we report the analysis of the efficiency and specificity of the integrase activity of TrwC in human cells, using the type IV secretion system of the human pathogen Bartonella henselae to introduce relaxase-DNA complexes...
June 15, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28403499/psychische-belastungsfaktoren-in-der-arbeitswelt-modelle-und-pr%C3%A3-vention
#20
Florian Junne, Monika Rieger, Martina Michaelis, Christoph Nikendei, Harald Gündel, Stephan Zipfel, Eva Rothermund
Psycho-mental stressors and increased perceived stress in workplace settings may determine the onset and course of stress-related mental and psychosomatic disorders. For the description of psycho-mental stressors three distinct models have widely been used in the analyses of the matter: the Demand-Control-Model by Karasek and Theorell, the Effort-Reward-Imbalance Model by Siegrist, and the Model of Organisational Justice.The interactional or social dimension in work-place settings can be seen as a cross-sectional dimension to the above mentioned models...
April 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
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