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https://www.readbyqxmd.com/read/28636868/deadly-liver-mob-opening-the-door-improving-sexual-health-pathways-for-aboriginal-people-in-western-sydney
#1
Karen Biggs, Jennifer Walsh, Catriona Ooi
BACKGROUND: The Deadly Liver Mob project (DLM) is an incentive-based, peer-driven health promotion intervention for Aboriginal people, focusing on hepatitis C and offering education and screening for sexually transmissible infections (STI) and blood-borne viruses (BBV). This study aims to assess the DLM effect on attendance and STI/BBV screening, describe BBV risk factors and report infection rates among Aboriginal people attending Western Sydney Sexual Health Centre (WSSHC). METHODS: A retrospective review of Aboriginal clients during the first year of the DLM project was compared with Aboriginal clients who attended during the 5...
October 2016: Sexual Health
https://www.readbyqxmd.com/read/28593095/load-enhanced-movement-quality-screening-and-tactical-athleticism-an-extension-of-evidence
#2
Stephen M Glass, Randy J Schmitz, Christopher K Rhea, Scott E Ross
BACKGROUND: Military organizations use movement quality screening for prediction of injury risk and performance potential. Currently, evidence of an association between movement quality and performance is limited. Recent work has demonstrated that external loading strengthens the relationship between movement screens and performance outcomes. Such loading may therefore steer us toward robust implementations of movement quality screens while maintaining their appeal as cost effective, field-expedient tools...
June 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28585360/functional-and-phenotypic-analysis-of-basophils-allows-determining-distinct-subtypes-in-patients-with-chronic-urticaria
#3
Michèle Myriam Rauber, Julia Pickert, Lily Holiangu, Christian Möbs, Wolfgang Pfützner
BACKGROUND: Chronic urticaria (CU) is a frequent skin disease characterized by relapsing appearance of pruritic hives. While clinical symptoms are due to the release of histamine by cutaneous mast cells, the underlying pathophysiology is still unknown. However, previous studies indicate that basophils might be of relevance. Besides, the occurrence of autoantibodies against IgE or its receptor, FcεRI, and the therapeutic efficacy of anti-IgE antibodies imply that IgE-mediated mechanisms also play an important role in CU...
June 5, 2017: Allergy
https://www.readbyqxmd.com/read/28560890/book-review-misbehavior-in-organizations-a-dynamic-approach-cyberbullying-where-are-we-now-a-cross-national-understanding-infostorms-why-do-we-like-explaining-individual-behavior-on-the-social-net-stalker-hacker-voyeur-spy-a-psychoanalytic-study-of-erotomania
#4
Martin Guha
No abstract text is available yet for this article.
May 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28554256/integration-of-methane-removal-in-aerobic-anammox-based-granular-sludge-reactors
#5
Celia M Castro-Barros, Long T Ho, Mari K H Winkler, Eveline I P Volcke
Combined partial nitritation-anaerobic ammonium oxidation (anammox) processes have been widely applied for nitrogen removal from anaerobic digestion reject water. However, such streams also contain dissolved methane that can escape to the atmosphere, hence contributing to global warming. This study investigates the possibility of integrating methane removal in aerobic anammox-based granular sludge reactors, through modelling and simulation. Methane removal could be established through aerobic methane-oxidizing bacteria (MOB), denitrifying anaerobic methane-oxidizing bacteria (damoB, NO2(-) + CH4à N2 + CO2), and/or archaea (damoA, NO3(-) + CH4à NO2(-) + CO2)...
June 8, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28522884/profiles-of-periglomerular-cells-in-the-olfactory-bulb-of-prokineticin-type-2-receptor-deficient-mice
#6
Atsuko Kubo, Mitsugu Sujino, Koh-Hei Masumoto, Atsuko Fujioka, Toshio Terashima, Yasufumi Shigeyoshi, Mamoru Nagano
Both prokineticin receptor 2 (pkr2) and prokineticin 2 (pk2) gene-deficient mice have hypoplasia of the main olfactory bulb (MOB). This hypoplasia has been attributed to disruption of the glomerulus that is caused by loss of afferent projection from olfactory sensory neurons (OSN), and to the impaired migration of granule cells, a type of interneuron. In the present study, we examined whether migration of the second type of interneuron, periglomerular cells (PGC), is dependent on the pkr2 expression by observing the localization of distinct subpopulations of PGC: calretinin (CR)-, calbindin (CB)- and tyrosine hydroxylase (TH)-expressing neurons...
April 27, 2017: Acta Histochemica et Cytochemica
https://www.readbyqxmd.com/read/28516137/a-curated-dataset-of-complete-enterobacteriaceae-plasmids-compiled-from-the-ncbi-nucleotide-database
#7
Alex Orlek, Hang Phan, Anna E Sheppard, Michel Doumith, Matthew Ellington, Tim Peto, Derrick Crook, A Sarah Walker, Neil Woodford, Muna F Anjum, Nicole Stoesser
Thousands of plasmid sequences are now publicly available in the NCBI nucleotide database, but they are not reliably annotated to distinguish complete plasmids from plasmid fragments, such as gene or contig sequences; therefore, retrieving complete plasmids for downstream analyses is challenging. Here we present a curated dataset of complete bacterial plasmids from the clinically relevant Enterobacteriaceae family. The dataset was compiled from the NCBI nucleotide database using curation steps designed to exclude incomplete plasmid sequences, and chromosomal sequences misannotated as plasmids...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28512362/-copenhagen-psychosocial-questionnaire-copsoq-psychometric-properties-of-selected-scales-in-the-polish-version
#8
Maria Widerszal-Bazyl
BACKGROUND: The Copenhagen Psychosocial Questionniare (COPSOQ) has many advantages as compared to other similar instruments, i.a., it is not related to one single theoretical model and it measures a wide spectrum of psychosocial working conditions that have shown proven impact on health. The aim of the article is to summarize information on psychometric properties of 11 scales in the Polish version: Quantitative Demands, Emotional Demands, Influence at Work, Social Support, Possibilities for Development, Meaning of Work, Role Clarity, Quality of Leadership, Job Insecurity, Job Satisfaction, and General Health...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28496397/conflicts-at-work-are-associated-with-a-higher-risk-of-cardiovascular-disease
#9
Louis Jacob, Karel Kostev
Background: Only few authors have analyzed the impact of workplace conflicts and the resulting stress on the risk of developing cardiovascular disorders. The goal of this study was to analyze the association between workplace conflicts and cardiovascular disorders in patients treated by German general practitioners. Methods: Patients with an initial documentation of a workplace conflict experience between 2005 and 2014 were identified in 699 general practitioner practices (index date). We included only those who were between the ages of 18 and 65 years, had a follow-up time of at least 180 days after the index date, and had not been diagnosed with angina pectoris, myocardial infarction, coronary heart diseases, or stroke prior to the documentation of the workplace mobbing...
2017: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/28487684/relative-abundance-and-diversity-of-bacterial-methanotrophs-at-the-oxic-anoxic-interface-of-the-congo-deep-sea-fan
#10
Sandrine Bessette, Yann Moalic, Sébastien Gautey, Françoise Lesongeur, Anne Godfroy, Laurent Toffin
Sitting at ∼5,000 m water depth on the Congo-Angola margin and ∼760 km offshore of the West African coast, the recent lobe complex of the Congo deep-sea fan receives large amounts of fluvial sediments (3-5% organic carbon). This organic-rich sedimentation area harbors habitats with chemosynthetic communities similar to those of cold seeps. In this study, we investigated relative abundance, diversity and distribution of aerobic methane-oxidizing bacteria (MOB) communities at the oxic-anoxic interface of sedimentary habitats by using fluorescence in situ hybridization and comparative sequence analysis of particulate mono-oxygenase (pmoA) genes...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28435006/horizontal-transfer-of-chromosomal-markers-mediated-by-the-large-conjugative-plasmid-pxo16-from-bacillus-thuringiensis-serovar-israelensis
#11
Lionel Makart, Florian Commans, Annika Gillis, Jacques Mahillon
pXO16, a large plasmid originating from Bacillus thuringiensis serovar israelensis, displays unique conjugation capacities: besides efficient self-transfer, it is able to mobilize and retro-mobilize non-conjugative plasmids, including those missing an oriT and/or a mob gene, also known as "non-mobilizable" plasmids. In this paper, another peculiar transfer property of pXO16 is described. This element is indeed able to transfer chromosomal loci at frequencies of ca. 10(-5)-10(-6) transconjugants/donor cell. Whereas most other chromosomal transfer systems occur via the integration of the conjugative elements into the chromosome prior to its transfer, pXO16 appears to transfer the chromosomal markers in the absence of physical integration, but rather through a "donation-type" mobilization...
April 20, 2017: Plasmid
https://www.readbyqxmd.com/read/28411218/the-conjugative-relaxase-trwc-promotes-integration-of-foreign-dna-in-the-human-genome
#12
Coral González-Prieto, Richard Gabriel, Christoph Dehio, Manfred Schmidt, Matxalen Llosa
Bacterial conjugation is a mechanism of horizontal DNA transfer. The relaxase TrwC of the conjugative plasmid R388 cleaves one strand of the transferred DNA at the oriT, covalently attaches to it and leads the ssDNA into the recipient cell. In addition, TrwC catalyzes site-specific integration of the transferred DNA into its target sequence present in the genome of the recipient bacterium. Here, we report the analysis of the efficiency and specificity of the integrase activity of TrwC in human cells, using the Type IV Secretion System of the human pathogen Bartonella henselae to introduce relaxase-DNA complexes...
April 14, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28403499/psychische-belastungsfaktoren-in-der-arbeitswelt-modelle-und-pr%C3%A3-vention
#13
Florian Junne, Monika Rieger, Martina Michaelis, Christoph Nikendei, Harald Gündel, Stephan Zipfel, Eva Rothermund
Psycho-mental stressors and increased perceived stress in workplace settings may determine the onset and course of stress-related mental and psychosomatic disorders. For the description of psycho-mental stressors three distinct models have widely been used in the analyses of the matter: the Demand-Control-Model by Karasek and Theorell, the Effort-Reward-Imbalance Model by Siegrist, and the Model of Organisational Justice.The interactional or social dimension in work-place settings can be seen as a cross-sectional dimension to the above mentioned models...
April 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28394098/boron-dependency-of-molybdenum-boride-electrocatalysts-for-the-hydrogen-evolution-reaction
#14
Hyounmyung Park, Andrew Encinas, Jan P Scheifers, Yuemei Zhang, Boniface P T Fokwa
Molybdenum-based materials have been considered as alternative catalysts to noble metals, such as platinum, for the hydrogen evolution reaction (HER). We have synthesized four binary bulk molybdenum borides Mo2 B, α-MoB, β-MoB, and MoB2 by arc-melting. All four phases were tested for their electrocatalytic activity (linear sweep voltammetry) and stability (cyclic voltammetry) with respect to the HER in acidic conditions. Three of these phases were studied for their HER activity and by X-ray photoelectron spectroscopy (XPS) for the first time; MoB2 and β-MoB show excellent activity in the same range as the recently reported α-MoB and β-Mo2 C phases, while the molybdenum richest phase Mo2 B show significantly lower HER activity, indicating a strong boron-dependency of these borides for the HER...
May 8, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28385419/vital-signs-and-other-observations-used-to-detect-deterioration-in-pregnant-women-an-analysis-of-vital-sign-charts-in-consultant-led-uk-maternity-units
#15
G B Smith, R Isaacs, L Andrews, M Y K Wee, E van Teijlingen, D E Bick, V Hundley
BACKGROUND: Obstetric early warning systems are recommended for monitoring hospitalised pregnant and postnatal women. We decided to compare: (i) vital sign values used to define physiological normality; (ii) symptoms and signs used to escalate care; (iii) type of chart used; and (iv) presence of explicit instructions for escalating care. METHODS: One-hundred-and-twenty obstetric early warning charts and escalation protocols were obtained from consultant-led maternity units in the UK and Channel Islands...
May 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28382809/the-italian-version-of-the-trunk-impairment-scale-development-and-psychometric-properties
#16
Bruna Lombardi, Annalisa Orioli, Davide Casavola, Matteo Paci
BACKGROUND: The Trunk Impairment Scale (TIS) is a widely used tool aimed to evaluate trunk motor impairment for stroke patients. A validation trial of a translated form of the TIS was never conducted within an Italian population. AIM: To describe translation, cultural adaptation, and validation (internal consistency, reliability, and validity) of the Italian version of the TIS (TIS-I). DESIGN: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire...
April 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28378968/patient-aggression-towards-different-professional-groups-of-healthcare-workers
#17
Krystyna Kowalczuk, Elżbieta Krajewska-Kułak
INTRODUCTION: Patient aggression affects healthcare quality and, in extreme situations, may even lead to medical malpractice. Little is known, however, about the specific distribution of health care professionals' exposure to patient aggression in various countries. OBJECTIVE: The aim of this study was to assess the exposure of various professional groups of healthcare personnel to patient aggression, and to identify potential determinants (medical profession, age, gender, professional experience and employment at outpatient/inpatient healthcare units) of this exposure...
March 31, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28373298/mob1-mediated-phospho-recognition-in-the-core-mammalian-hippo-pathway
#18
Amber L Couzens, Shawn Xiong, James D R Knight, Daniel Y Mao, Sebastian Guettler, Sarah Picaud, Igor Kurinov, Panagis Filippakopoulos, Frank Sicheri, Anne-Claude Gingras
The Hippo tumor suppressor pathway regulates organ size and tissue homoeostasis in response to diverse signaling inputs. The core of the pathway consists of a short kinase cascade: MST1 and MST2 phosphorylate and activate LATS1 and LATS2, which in turn phosphorylate and inactivate key transcriptional coactivators, YAP1 and TAZ (gene WWTR1). The MOB1 adapter protein regulates both phosphorylation reactions firstly by concurrently binding to the upstream MST and downstream LATS kinases to enable the trans phosphorylation reaction, and secondly by allosterically activating the catalytic function of LATS1 and LATS2 to directly stimulate phosphorylation of YAP and TAZ...
June 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28357001/laser-assisted-non-surgical-periodontal-therapy-a-double-blind-randomized-clinical-trial
#19
Joseph D Everett, Jeffrey A Rossmann, David G Kerns, Ibtisam Al-Hashimi
The objective of this study was to examine potential benefits of using laser therapy for secular decontamination in conjunction with scaling and root planing in the treatment of chronic periodontitis. The study was performed on 173 teeth in 14 patients in a split-mouth design, one side received scaling and root planing followed by laser therapy using a carbon dioxide (CO2) laser with an ablative handpiece (test group); the contralateral side received scaling and root planing without laser (control group). Clinical and laboratory parameters were evaluated prior to treatment and at 3 and 6 months following therapy; clinical measurements were performed by two blinded examiners...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28346423/mob1-yap1-taz-nkx2-1-axis-controls-bronchioalveolar-cell-differentiation-adhesion-and-tumour-formation
#20
K Otsubo, H Goto, M Nishio, K Kawamura, S Yanagi, W Nishie, T Sasaki, T Maehama, H Nishina, K Mimori, T Nakano, H Shimizu, T W Mak, K Nakao, Y Nakanishi, A Suzuki
Mps One Binder Kinase Activator (MOB)1A/1B are core components of the Hippo pathway. These proteins, which coactivate LArge Tumour Suppressor homologue kinases, are also tumour suppressors. To investigate MOB1A/B's roles in normal physiology and lung cancer, we generated doxycycline (Dox)-inducible, bronchioalveolar epithelium-specific, null mutations of MOB1A/B in mice (SPC-rtTA/(tetO)7-Cre/Mob1a(flox/flox)/Mob1b(-/-); termed luMob1DKO mice). Most mutants (70%) receiving Dox in utero (luMob1DKO (E6.5-18.5) mice) died of hypoxia within 1 h post-birth...
March 27, 2017: Oncogene
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