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https://www.readbyqxmd.com/read/29778079/advances-in-understanding-the-response-of-fish-to-linear-alcohols-in-the-environment
#1
Scott E Belanger, Jane M Rawlings, Ricky Stackhouse
Short to long chain alcohols have a range of ecotoxicity to aquatic life driven by hydrophobic interactions with biological membranes. Carbon chain length and octanol:water partitioning coefficients are surrogates for hydrophobicity and strongly relate to aquatic toxicity. In these investigations, the toxicity of ethanol to 1-n-dodecanol to juvenile fish in standard acute toxicity tests is reviewed. Toxicity tests employing fish embryos (zebrafish Danio rerio and fathead minnow Pimephales promelas) in the Fish Embryo Test (OECD 236) format were conducted from C2 to C10 to compare against standard juvenile fish toxicity...
April 25, 2018: Chemosphere
https://www.readbyqxmd.com/read/29771804/preemptive-analgesia-decreases-pain-following-anorectal-surgery-a-prospective-randomized-double-blinded-placebo-controlled-trial
#2
Justin T Van Backer, Matthew R Jordan, Danielle T Leahy, Jesse S Moore, Peter Callas, Timothy Dominick, Peter A Cataldo
BACKGROUND: Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery. Both central and peripheral pain receptor sensitization are thought to contribute to postoperative pain. Blocking these receptors and preempting sensitization prevents hyperalgesia leading to lower pain medication requirements. Studies in the orthopedic, urologic, and gynecologic literature support this practice, but the use of preemptive analgesia in anorectal surgery is understudied...
May 15, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29768663/death-of-a-female-prostitute-due-to-intestinal-obstruction-by-an-unknown-substance
#3
Marek Dokoupil, Klára Marecová, Petr Handlos, Petr Březina
A young adult black female, known to be a prostitute and suspected of smuggling narcotics, was found dead in her apartment in a state of early decomposition. Oval-shaped gray-white masses of exogenous origin protruded from the anus. The autopsy showed dilatation of the folds of the large intestine, which were almost completely filled with these oval-shaped gray-white masses of foreign material. The uterus was enlarged with multiple large leiomyomas. Toxicological tests of blood and the foreign material revealed no toxicologically relevant substances...
May 16, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29762112/lumbar-discography-is-associated-with-poor-return-to-work-status-following-lumbar-fusion-surgery-in-a-workers-compensation-setting
#4
Joshua T Anderson, Jeffrey A O'Donnell, Arnold R Haas, Rick Percy, Stephen T Woods, Uri M Ahn, Nicholas U Ahn
Lumbar discography (LD) is used to guide surgical decision making in patients with degenerative disc disease (DDD). Its safety and diagnostic accuracy are under contention. This study evaluates LD's efficacy within the workers' compensation (WC) population. Multivariate logistic regression analysis was used to determine the impact that undergoing LD before lumbar fusion for DDD had on return to work (RTW) rates among 1407 WC subjects. Discography was negatively associated with RTW status (p = .042; OR 0.76); 22...
2018: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29759233/critical-review-of-dog-detection-and-the-influences-of-physiology-training-and-analytical-methodologies
#5
REVIEW
J E Hayes, P D McGreevy, S L Forbes, G Laing, R M Stuetz
Detection dogs serve a plethora of roles within modern society, and are relied upon to identify threats such as explosives and narcotics. Despite their importance, research and training regarding detection dogs has involved ambiguity. This is partially due to the fact that the assessment of effectiveness regarding detection dogs continues to be entrenched within a traditional, non-scientific understanding. Furthermore, the capabilities of detection dogs are also based on their olfactory physiology and training methodologies, both of which are hampered by knowledge gaps...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29757882/american-association-of-nurse-practitioners-national-nurse-practitioner-sample-survey-update-on-acute-care-nurse-practitioner-practice
#6
Ruth Kleinpell, Michelle L Cook, Diane L Padden
BACKGROUND AND PURPOSE: Data from national surveys on the practice of nurse practitioners (NPs) provides valuable information on aspects of practice, demographic characteristics of providers and patients, plans for continued employment, and role satisfaction. The American Association of Nurse Practitioners (AANP) has been conducting the AANP Sample Survey since 1988. METHODS: The most recent AANP Sample Survey was conducted in 2016 with a random stratified survey of 40,000 NPs...
March 2018: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29756302/velopharyngeal-dysfunction-from-intranasal-substance-abuse-case-series-and-review-of-literature
#7
Peng You, Linda Chow, Anne Dworschak-Stokan, Murad Husein
OBJECTIVE: Intranasal substance abuse with cocaine or opioids can result in complications involving the midline nasal and oral structures. When the defect involves the velopharyngeal musculature, this leads to velopharyngeal dysfunction (VPD). This article aims to illustrate this clinical entity through a series of four patients and a review of the literature. METHODS: A series of four cases of VPD due to intranasal narcotic use and their management are discussed...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29756066/postanaesthetic-shivering-from-pathophysiology-to-prevention
#8
REVIEW
Maria Bermudez Lopez
Postoperative shivering is a common complication of anaesthesia. Shivering is believed to increase oxygen consumption, increase the risk of hypoxemia, induce lactic acidosis, and catecholamine release. Therefore, it might increase the postoperative complications especially in high-risk patients. Moreover, shivering is one of the leading causes of discomfort for postsurgical patients. Shivering is usually triggered by hypothermia. However, it occurs even in normothermic patients during the perioperative period...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29754116/criminality-in-greece-during-the-years-of-financial-crisis-2008-2014
#9
G Tsouvelas, G Konstantakopoulos, A Vakirtzis, O Giotakos, T Papaslanis, V Kontaxakis
The link between poverty, unemployment and economic downturns and increases in crime rates has long been the subject of social science study. However, the relationships between these phenomena has not been studied sufficiently and through time in most European countries that suffered, or, like Greece, are still suffering the recent financial crisis. We examined if the recent financial crisis in Greece has coincided with an increase in crime, analyzing crime rates since the start of the financial crisis and over an extensive time period (7 years)...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29750761/-toradol%C3%A2-following-breast-surgery-is-there-an-increased-risk-of-hematoma
#10
Brittany N Nguyen, Ruth J Barta, Christine Stewart, Cherrie A Heinrich
BACKGROUND: Ketorolac tromethamine (Toradol), a nonsteroidal antiinflammatory drug, is used with increased frequency given its success in postoperative pain control and the subsequent decreased need for narcotics. Its use has been limited in plastic surgery for fear of postoperative bleeding and hematoma formation. In this study of breast surgery patients, we investigated whether ketorolac increased the risk of postoperative hematoma formation. METHODS: After obtaining institutional review board approval, we retrospectively reviewed the records of patients undergoing breast surgery (breast reduction and autologous or implant based reconstruction) from January 2012 through December 2014...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29750760/prospective-randomized-controlled-comparison-of-local-anesthetic-infusion-pump-versus-depofoam-bupivacaine-for-pain-management-after-unilateral-delayed-deep-inferior-epigastric-perforator-free-flap-reconstruction
#11
James Gatherwright, Rebecca Knackstedt, Amir Ghaznavi, Steven Bernard, Graham Schwarz, Andrea Moreira, Raffi Gurunluoglu, Risal Djohan
BACKGROUND: Effective postsurgical analgesia is a critical aspect of patient recovery. The goal of this prospective, randomized, controlled, blinded study was to examine the effect that liposomal bupivacaine delivered via a transversus abdominis plane (TAP) block has on pain control in women undergoing unilateral deep inferior epigastic perforator reconstruction. METHODS: IRB approval was granted for this prospective study. Patients were eligible if they were undergoing unilateral, delayed DIEP reconstruction...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29749582/naloxone-induced-non-cardiogenic-pulmonary-edema-a-case-report
#12
Nasheena Jiwa, Himesh Sheth, Richard Silverman
A 22-year-old man was admitted for an elective right-shoulder open subacromial decompression and distal clavicle excision. He received a single intravenous dose of fentanyl 50 μg for anesthesia. His procedure was completed without intra-operative complications; however, he developed post-operative respiratory depression in the setting of narcotic administration. He was given naloxone 0.2 mg intravenously once to reverse this effect, which subsequently led to acute hypoxic respiratory failure secondary to pulmonary edema shortly after administration of naloxone...
May 10, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29748122/the-tipping-point-for-931-elective-shoulder-arthroplasties
#13
Jeremy S Somerson, Jason E Hsu, Moni B Neradilek, Frederick A Matsen
BACKGROUND: A patient with arthritis usually experiences the progression of symptoms over time. At some stage, the patient may decide that the symptoms have reached a level of severity that leads him or her to elect to proceed with joint replacement; we refer to this degree of symptom severity as the "tipping point." Our goal was to study the factors that influenced the tipping point for patients undergoing elective shoulder arthroplasty. METHODS: We analyzed the characteristics of 931 patients undergoing shoulder arthroplasty to determine the factors affecting the tipping point as characterized by the patients' comfort and function at the time they determined their symptoms had progressed to the point when this elective surgery was merited...
May 7, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29746919/opioid-medication-use-in-the-surgical-patient-an-assessment-of-prescribing-patterns-and-utilization
#14
Wen Hui Tan, Jennifer Yu, Sara Feaman, Jared M McAllister, Lindsey G Kahan, Mary A Quasebarth, Jeffrey A Blatnik, J Christopher Eagon, Michael M Awad, L Michael Brunt
BACKGROUND: With the epidemic of prescription opioid abuse in the United States, rates of opioid-related unintentional deaths have risen dramatically. However, little data exists comparing postoperative opioid prescriptions with patient use. We sought to better elucidate this relationship in surgical patients. STUDY DESIGN: A prospective cohort study was conducted of narcotic-naïve patients undergoing open and laparoscopic abdominal procedures on a minimally invasive surgery service...
May 7, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29742667/total-laparoscopic-hysterectomy-under-regional-anesthesia
#15
Nash S Moawad, Estefania Santamaria Flores, Linda Le-Wendling, Martina T Sumner, F Kayser Enneking
BACKGROUND: Laparoscopic hysterectomies comprise a large proportion of all hysterectomies in the United States. Procedures completed under regional anesthesia pose a number of benefits to patients, but laparoscopic hysterectomies traditionally have been performed under general anesthesia. We describe a case of total laparoscopic hysterectomy under epidural anesthesia with the patient fully awake. CASE: A 51-year-old woman with abnormal uterine bleeding underwent an uncomplicated total laparoscopic hysterectomy, bilateral salpingectomy, and excision of endometriosis...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29738856/minimally-invasive-transforaminal-versus-direct-lateral-lumbar-interbody-fusion-effect-on-return-t-o-work-narcotic-usage-and-quality-of-life
#16
Terence Verla, Lona Winnegan, Rory Mayer, Jacob Cherian, Nasser Yaghi, Ali Palejwala, Ibrahim Omeis
No abstract text is available yet for this article.
May 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29732904/characterization-categorization-and-5-year-mortality-of-medicine-high-utilizer-inpatients
#17
Joyeeta G Dastidar, Min Jiang
BACKGROUND: Patients who are frequently admitted to Medicine inpatient services comprise a distinct subset of readmitted patients about whom not much is known. OBJECTIVE: We sought to characterize this group including mortality rates, with the goal of better understanding this population. DESIGN: Observational study of frequently hospitalized patients defined as 4 or more admissions over a 6-month period, with hospitalization defined as nonelective admission to the hospital...
January 1, 2018: Journal of Palliative Care
https://www.readbyqxmd.com/read/29732387/transversus-abdominis-plane-blockade-as-part-of-a-multimodal-postoperative-analgesia-plan-in-patients-undergoing-radical-cystectomy
#18
Richard S Matulewicz, Mehul Patel, Brian J Jordan, Jacqueline Morano, Brendan Frainey, Yasin Bhanji, Mahreen Bux, Antoun Nader, Shilajit D Kundu, Joshua J Meeks
Background: Radical cystectomy (RC) is a morbid procedure with frequent complications that may benefit from implementation of an enhanced recovery after surgery (ERAS) protocol. Objective: To examine the benefits of a multimodal analgesic plan that uses continuous transversus abdominis plane (TAP) blockade as part of an ERAS protocol after RC. Methods: A retrospective comparison of consecutive patients undergoing RC over a 4-year period was conducted...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29729360/intra-operative-onabotunlinumtoxin-a-reduces-post-operative-narcotic-and-anticholinergic-requirements-after-continent-bladder-reconstruction
#19
Molly E Fuchs, Nicholas Beecroft, Daryl J McLeod, Daniel G Dajusta, Christina B Ching
OBJECTIVE: To determine if intra-detrusor injection of Onobotulinumtoxin-A (BTX-A) would reduce post-operative narcotic and anticholinergic requirements in children undergoing open continent bladder reconstruction. METHODS: After IRB approval, we retrospectively reviewed all bladder reconstructions performed. Bladder reconstruction was defined as the following procedures in any combination: bladder neck reconstruction and sling, bladder neck closure, mitrofanoff, monti or bladder augmentation We identified 15 children who underwent reconstruction with BTX-A injection and compared these to 15 children who did not receive BTX-A...
May 2, 2018: Urology
https://www.readbyqxmd.com/read/29721629/direct-visualization-transversus-abdominis-plane-blocks-offer-superior-pain-control-compared-to-ultrasound-guided-blocks-following-open-posterior-component-separation-hernia-repairs
#20
J A Doble, J S Winder, S R Witte, E M Pauli
PURPOSE: Transversus abdominis plane (TAP) blockade with long-acting anesthetic can be used during open ventral hernia repair (VHR) with posterior component separation (PCS). TAP block can be performed under ultrasound guidance (US-TAP) or under direct visualization (DV-TAP). We hypothesized that US-TAP and DV-TAP provide equivalent postoperative analgesia following open VHR. METHODS: A retrospective review of patients undergoing open VHR with PCS who received TAP blocks with 266 mg of liposomal bupivacaine was performed...
May 2, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
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