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https://www.readbyqxmd.com/read/28549370/assessment-of-the-influence-of-key-abiotic-factors-on-the-alternative-microcystin-degradation-pathway-s-mlr-a-detailed-comparison-with-the-mlr-route-mlr
#1
Jesús Morón-López, Lucía Nieto-Reyes, Rehab El-Shehawy
Cyanobacterial proliferation and toxin production in water bodies around the world have led to global concern about the control of these issues. Indigenous bacteria have been shown to degrade the cyanotoxin microcystin (MC) in natural environments. The mlr cluster has been widely used as a marker for microcystin biodegradation; however, recent studies have shown that alternative pathway(s) also contribute to the natural removal of MCs in the ecosystem. The main objective of this study is to provide initial insights concerning how key abiotic factors affect the rate of MC biodegradation via alternative pathway(s) and to provide a detailed comparison with the mlr(+) pathway...
May 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28549360/-intercarpal-fusion-as-a-salvage-procedure-in-kienb%C3%A3-ck-disease
#2
M Puig-Zentella, J A Rivas-Montero, E Hernández-Méndez-Villamil, A J Espinosa-Gutiérrez
INTRODUCTION: Functional results of four surgical techniques to resolve the IIIB-IV Litchman's stage of the Kienböck disease were analyzed. We observed the evolution from 2000 to 2015. MATERIAL AND METHODS: Transversal retrospective study of 33 patients treated with different surgical techniques and evaluated with Quick-DASH scale, dynamometer and EVA. RESULTS: Less functional limitation was found in the patients who underwent the intercarpal fusion with or without neurotomy of the posterior interosseous...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28549354/the-facespan-the-perceptual-span-for-face-recognition
#3
Michael Papinutto, Junpeng Lao, Meike Ramon, Roberto Caldara, Sébastien Miellet
In reading, the perceptual span is a well-established concept that refers to the amount of information that can be read in a single fixation. Surprisingly, despite extensive empirical interest in determining the perceptual strategies deployed to process faces and an ongoing debate regarding the factors or mechanism(s) underlying efficient face processing, the perceptual span for faces-the Facespan-remains undetermined. To address this issue, we applied the gaze-contingent Spotlight technique implemented in an old-new face recognition paradigm...
May 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28549345/a-novel-synthetic-derivative-of-quercetin-8-trifluoromethyl-3-5-7-3-4-o-pentamethyl-quercetin-inhibits-bladder-cancer-growth-by-targeting-the-ampk-mtor-signaling-pathway
#4
Ting Tao, Caimei He, Jun Deng, Yanjun Huang, Qiongli Su, Mei Peng, Meiling Yi, Kwame Oteng Darko, Hui Zou, Xiaoping Yang
Quercetin is a naturally existing compound and shows attractive anticancer properties for a variety of solid tumors including glioma, bladder cancer, hepatocellular carcinoma, breast cancer, hematological malignancies and prostate carcinoma. However, these anticancer properties have not been clinically approved due to unclear mechanistic information and its low bioactivity. In our previous study, we elucidated that quercetin activates AMPK pathway which is the major mechanism for its unique anticancer effect in bladder cancer...
May 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28549326/electrochemical-decolorization-of-methyl-red-by-ruo2-iro2-tio2-electrode-and-biodegradation-with-pseudomonas-stutzeri-mn1-and-acinetobacter-baumannii-mn3-an-integrated-approach
#5
Kuppusamy Sathishkumar, Sivaji Sathiyaraj, Punniyakotti Parthipan, Agrawal Akhil, Kadarkarai Murugan, Aruliah Rajasekar
Textile effluent consists of enormous quantities of toxic dyes, which are being discharged into natural aqueous system and thus contaminate the water quality. Hence it is important to develop an eco-friendly and cost effective technology to treat the dyes contaminated wastewater. In this research, an integrated approach of electrochemical oxidation (EO) and biodegradation process (BP) was studied of methyl red (MR) dye. In EO, RuO2-IrO2-TiO2 is used as anode and titanium mesh electrode as cathode. This was followed by BP of the treated EO effluent...
May 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28549314/application-of-novel-metal-organic-framework-mil-53-fe-and-its-magnetic-hybrid-for-removal-of-pharmaceutical-pollutant-doxycycline-from-aqueous-solutions
#6
Shakiba Naeimi, Hossein Faghihian
As a pharmaceutical pollutant, doxycycline causes contamination when enters into the environment. In this research MIL-53(Fe), and its magnetic hybrid MIL-53(Fe)/Fe3O4 were synthesized and employed for removal of doxycycline from aqueous solutions. The adsorbents were characterized by XRD, SEM, BET, FTIR, EDAX, VSM and TG-DTG technique. The effect of different variables such as DOC concentration, pH, contacting time, and adsorbent dose on the removal efficiency was studied and under optimized conditions the adsorption capacity of 322mgg(-1) was obtained...
May 11, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28549304/landowner-preferences-for-wetlands-conservation-programs-in-two-southern-ontario-watersheds
#7
Ryan Trenholm, Wolfgang Haider, Van Lantz, Duncan Knowler, Pascal Haegeli
Wetlands in the region of Southern Ontario, Canada have declined substantially from their historic area. Existing regulations and programs have not abated this decline. However, reversing this trend by protecting or restoring wetlands will increase the supply of important ecosystem services. In particular, these actions will contribute to moderating the impacts of extreme weather predicted to result from climate change as well as reducing phosphorous loads in Lake Erie and ensuing eutrophication. Since the majority of land in the region is privately owned, landowners can play an important role...
May 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28549289/identifying-the-source-of-zn-in-soils-around-a-zn-smelter-using-pb-isotope-ratios-and-mineralogical-analysis
#8
Soo-Kyung Jeon, Man Jae Kwon, Jung-Seok Yang, Seunghak Lee
The contribution by anthropogenic sources to abnormally high Zn concentrations in soils with naturally abundant Zn was investigated at a contaminated site surrounding a Zn smelter in eastern Korea. Nineteen soil samples were collected within a 2km radius of the smelter, and analyzed for metal concentrations and Pb isotope ratios using an inductively coupled plasma-optical emission spectrometer and -mass spectrometer, respectively. Higher Zn concentrations in locations closer to the smelter implied that the smelter was the source of the Zn pollution...
May 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28549233/processing-the-papal-encyclical-through-perceptual-filters-pope-francis-identity-protective-cognition-and-climate-change-concern
#9
Asheley R Landrum, Robert B Lull, Heather Akin, Ariel Hasell, Kathleen Hall Jamieson
Previous research suggests that when individuals encounter new information, they interpret it through perceptual 'filters' of prior beliefs, relevant social identities, and messenger credibility. In short, evaluations are not based solely on message accuracy, but also on the extent to which the message and messenger are amenable to the values of one's social groups. Here, we use the release of Pope Francis's 2015 encyclical as the context for a natural experiment to examine the role of prior values in climate change cognition...
May 23, 2017: Cognition
https://www.readbyqxmd.com/read/28549212/synthesis-of-four-monoterpene-derived-organosulfates-and-their-quantification-in-atmospheric-aerosol-samples
#10
Yuchen Wang, Jingyun Ren, X H Hilda Huang, Rongbiao Tong, Jian Zhen Yu
Monoterpenes, a major class of biogenic volatile organic compounds, are known to produce oxidation products that further react with sulfate to form organosulfates. The accurate quantification of monoterpene-derived organosulfates (OSs) is necessary for quantifying this controllable aerosol source; however, it has been hampered by a lack of authentic standards. Here we report a unified synthesis strategy starting from the respective monoterpene through Upjohn dihydroxylation or Sharpless asymmetric dihydroxylation followed by mono-sulfation with sulfur trioxide-pyridine complex...
May 26, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28549204/setd5-gene-variant-associated-with-mild-intellectual-disability-a-case-report
#11
E Stur, L A Soares, I D Louro
The recent advent of exome sequencing has allowed for the identification of pathogenic gene variants responsible for a variety of diseases that were previously clinically diagnosed, with no underlying molecular etiology. Among these conditions, intellectual disability is a prevalent heterogeneous condition, presenting itself in a large spectrum of intensity, in some cases associated with congenital malformations, behavioral and various other intellectual development alterations. Here we report on a 36-year-old male patient, with a mild intellectual disability that remained undiagnosed at the molecular level for all his life...
May 25, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28549194/disentangling-timing-of-admixture-patterns-of-introgression-and-phenotypic-indicators-in-a-hybridizing-wolf-population
#12
M Galaverni, R Caniglia, L Pagani, E Fabbri, A Boattini, E Randi
Hybridization is a natural or anthropogenic process that can deeply affect the genetic make-up of populations, possibly decreasing individual fitness but sometimes favouring local adaptations. The population of Italian wolves (Canis lupus), after protracted demographic declines and isolation, is currently expanding in anthropic areas, with documented cases of hybridization with stray domestic dogs. However, identifying admixture patterns in deeply introgressed populations is far from trivial. In this study, we used a panel of 170,000 SNPs analysed with multivariate, Bayesian and local ancestry reconstruction methods to identify hybrids, estimate their ancestry proportions and timing since admixture...
May 26, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28549186/applying-within-family-differences-approaches-to-enhance-understanding-of-the-complexity-of-intergenerational-relations
#13
J Jill Suitor, Megan Gilligan, Karl Pillemer, Karen L Fingerman, Kyungmin Kim, Merril Silverstein, Vern L Bengtson
Objectives: The role of family relationships in the lives of older adults has received substantial attention in recent decades. Scholars have increasingly looked beyond simple models of family relations to approaches that recognize the complex and sometimes contradictory nature of these ties. One of the most exciting conceptual and methodological developments is the application of within-family differences approaches. In this paper, we focus on the ways in which such within-family approaches can extend the understanding of patterns and consequences of intergenerational ties in adulthood...
May 25, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28549184/coiled-coil-interactions-mediate-serine-integrase-directionality
#14
Kushol Gupta, Robert Sharp, Jimmy B Yuan, Huiguang Li, Gregory D Van Duyne
Serine integrases are bacteriophage enzymes that carry out site-specific integration and excision of their viral genomes. The integration reaction is highly directional; recombination between the phage attachment site attP and the host attachment site attB to form the hybrid sites attL and attR is essentially irreversible. In a recent model, extended coiled-coil (CC) domains in the integrase subunits are proposed to interact in a way that favors the attPxattB reaction but inhibits the attLxattR reaction. Here, we show for the Listeria innocua integrase (LI Int) system that the CC domain promotes self-interaction in isolated Int and when Int is bound to attachment sites...
May 26, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28549175/selfing-in-haploid-plants-and-efficacy-of-selection-codon-usage-bias-in-the-model-moss-physcomitrella-patens
#15
Péter Szövényi, Kristian K Ullrich, Stefan A Rensing, Daniel Lang, Nico van Gessel, Hans K Stenøien, Elena Conti, Ralf Reski
Long term reduction in effective population size will lead to major shift in genome evolution. In particular, when effective population size is small, genetic drift becomes dominant over natural selection. The onset of self-fertilization is one evolutionary event considerably reducing effective size of populations. Theory predicts that this reduction should be more dramatic in organisms capable for haploid than for diploid selfing. Although theoretically well-grounded, this assertion received mixed experimental support...
May 26, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28549123/working-conditions-in-the-explanation-of-occupational-inequalities-in-sickness-absence-in-the-french-sumer-study
#16
Isabelle Niedhammer, Thomas Lesuffleur, Sarah Memmi, Jean-François Chastang
: Explanations of social inequalities in sickness absence are lacking in the literature. Our objectives were to evaluate the contribution of various occupational exposures in explaining these inequalities in a national representative sample of employees. : The study was based on the cross-sectional sample of the SUMER 2010 survey that included 46 962 employees, 26 883 men and 20 079 women. Both sickness absence spells and days within the last 12 months, as health indicators, were studied. Occupation was used as a marker of social position...
May 25, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28549117/engineering-of-recombinant-wisteria-floribunda-agglutinin-specifically-binding-to-galnac%C3%AE-1-4glcnac-lacdinac
#17
Takashi Sato, Hiroaki Tateno, Hiroyuki Kaji, Yasunori Chiba, Tomomi Kubota, Jun Hirabayashi, Hisashi Narimatsu
Wisteria floribunda agglutinin (WFA) is a useful probe for distinguishing glycan structural alterations in diseases such as intrahepatic bile duct carcinoma and hepatic fibrosis; however, the gene encoding WFA has not been identified. Here, we identified the gene encoding WFA, and recombinant WFA was expressed in Escherichia coli and purified. The natural cDNA sequence obtained from wisteria seeds contained an open reading frame of 861 nucleotides encoding a WFA precursor, which included a hydrophobic signal peptide at the N-terminus, a propeptide at the C-terminus and a single cysteine (Cys) residue for dimer formation...
May 26, 2017: Glycobiology
https://www.readbyqxmd.com/read/28549080/life-history-traits-influence-the-strength-of-distance-and-density-dependence-at-different-life-stages-of-two-amazonian-palms
#18
Juanita Choo, Cecilia Carasco, Patricia Alvarez-Loayza, Beryl B Simpson, Evan P Economo
Background and Aims: Natural enemies are known to be important in regulating plant populations and contributing to species coexistence (Janzen-Connell effects). The strength of Janzen-Connell effects (both distance- and density-effects) varies across species, but the life history traits that may mediate such a variation are not well understood. This study examined Janzen-Connell effects across the life stages (seed through adult stages) of two sympatric palm species with distinct phenologies and shade tolerances, two traits that may mediate the strength and timing of Janzen-Connell effects...
May 26, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28549063/food-addiction-and-obesity-unnecessary-medicalization-of-hedonic-overeating
#19
REVIEW
Graham Finlayson
The concept of addiction is loaded with connotations and is often used for its political as much as its medical utility. The scientific case for 'food addiction' as a clinical phenotype currently rests on its association with generic diagnostic criteria for substance-related disorders being applied to everyday foods and eating-related problems. This has fused the concept of obesity with addiction regardless of whether it fits the definition. The hedonic, or reward, system can account for the ingestion of foods and drugs, confirming that they share neural substrates that differentiate liking and wanting...
May 26, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28549018/intimate-partner-violence-in-ophthalmology-a-global-call-to-action
#20
Ali R Cohen, Lynette M Renner, Erin M Shriver
PURPOSE OF REVIEW: Intimate partner violence (IPV) is a leading cause of death and disability worldwide. Despite increasing public awareness of IPV, little information is available regarding the prevalence, associated injury patterns, and impact of IPV as a mechanism of ocular and orbital trauma. The purpose of this review is to summarize the literature regarding the impact of IPV in ophthalmology and provide team members with guidance on appropriate practices for screening and referral...
April 25, 2017: Current Opinion in Ophthalmology
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